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Determination of biogenic amines in beers by LC-MS/MS
PublikacjaAnalysis of biogenic amines in beers was carried out by HPLC-MS/MS after their derivatization with p-toluenesulfonyl chloride (tosyl chloride). The developed method has been applied for analysis of eighteen biogenic amines in twelve samples of different kind of beers (Lager, Strong Lager, Schwarzbier, Weizenbier, Pils, nonalcoholic Pils, Stout). The method is sensitive and the results precise for majority of the analytes.
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Altered circadian genes expression in breast cancer tissue according to the clinical characteristics
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The impact of the Polish mass breast cancer screening program on prognosis in the Pomeranian Province
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Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
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Prognostic Significance of TOP2A Gene Dosage in HER-2-Negative Breast Cancer
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314 Osteopontin as a Potential Serum Marker in Early Breast Cancer-Preliminary Results
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Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease
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Application of a three‑dimensional (3D) breast cancer model to study macrophage polarization
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Hormonal Receptor Status Determines Prognostic Significance of FGFR2 in Invasive Breast Carcinoma
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FGF7 / FGFR2 – JunB signalling counteracts the effect of progesterone in luminal breast cancer
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Segmentation-Based BI-RADS Ensemble Classification of Breast Tumours in Ultrasound Images
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Impacting the Remedial Potential of Nano Delivery-Based Flavonoids for Breast Cancer Treatment
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The use of the static thermography in monitoring flap perfusion in breast reconstruction with TRAM flap
PublikacjaThis paper shows results of the static thermography for intraoperative and postoperative imaging of TRAM flap perfusion. The results were compared with the clinical examination of flap perfusion. The study was conducted on a group of 38 female patients who underwent breast reconstruction.
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Direct determination of cadaverine in the volatile fraction of aerobically stored chicken breast samples
PublikacjaTo supplement the currently used methods for poultry meat shelf life assessment, it might be necessary to develop a technique for rapid headspace analysis of volatiles with no prior sample preparation step. Biogenic amines, in particular cadaverine, are considered meat spoilage indicators. Described in this article are the results of a preliminary investigation of the applicability of proton transfer reaction mass spectrometry...
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Environmental exposure to cadmium in breast cancer – association with the Warburg effect and sensitivity to tamoxifen
PublikacjaThe association between cadmium and breast cancer remains unexplained due to inconsistent epidemiological data and unknown underlying mechanisms. This study aimed to assess the relationship between environmental exposure to cadmium and the Warburg effect in breast cancer and, thus, its possible interference with breast cancer treatment. The observational study in two groups of breast cancer patients indicated a positive correlation between...
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State of the art in sample preparation for human breast milk metabolomics—merits and limitations
PublikacjaHuman breast milk (HBM) contains metabolites that are diverse in chemical structure and concentration. These metabolites range from high-abundance to low-abundance compounds and from polar to nonpolar. This complex nature of HBM makes HBM samples difficult to analyze, especially in global metabolomic studies for the determination and characterization of complete sets of metabolites. In this review, the state of the art in sample...
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Segmentation-Based BI-RADS ensemble classification of breast tumours in ultrasound images
PublikacjaBackground: The development of computer-aided diagnosis systems in breast cancer imaging is exponential. Since 2016, 81 papers have described the automated segmentation of breast lesions in ultrasound images using arti- ficial intelligence. However, only two papers have dealt with complex BI-RADS classifications. Purpose: This study addresses the automatic classification of breast lesions into binary classes (benign vs. ma- lignant)...
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Laser beam angular stabilization system based on a compact interferometer and a precise double-wedge deflector
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Effect of Forecast Climate Changes on Water Needs of Giant Miscanthus Cultivated in the Kuyavia Region in Poland
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Custom FBGs inscription using modified phase mask method with precise micro- and nano-positioning
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Study on Technological Effects of a Precise Grooving of AlSi13MgCuNi Alloy with a Novel WCCo/PCD (DDCC) Inserts
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Deep-Learning-Based Precise Characterization of Microwave Transistors Using Fully-Automated Regression Surrogates
PublikacjaAccurate models of scattering and noise parameters of transistors are instrumental in facilitating design procedures of microwave devices such as low-noise amplifiers. Yet, data-driven modeling of transistors is a challenging endeavor due to complex relationships between transistor characteristics and its designable parameters, biasing conditions, and frequency. Artificial neural network (ANN)-based methods, including deep learning...
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Prognostic Value of TOP2A Gene Amplification and Chromosome 17 Polysomy in Early Breast Cancer
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Aggressive Phenotype of Cells Disseminated via Hematogenous and Lymphatic Route in Breast Cancer Patients
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Rapana thomasiana hemocyanin modified with ionic liquids with enhanced anti breast cancer activity
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Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells
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Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study
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Physical and psychological impairments of women with upper limb lymphedema following breast cancer treatment
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Nanosized zinc, epigenetic changes and its relationship with DMBA induced breast cancer in rats
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Physical activity, life satisfaction and adjustment to illness in women after treatment of breast cancer
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Effective kernel‐principal component analysis based approach for wisconsin breast cancer diagnosis
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Thyroid peroxidase (TPO) expressed in thyroid and breast tissues shows similar antigenic properties
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Expression of pendrin and NIS iodide transporters in human breast tumor and peri-tumoral tissue
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Patient with metastatic breast cancer presenting as acute cholecystitis with one-year survival on hormonotherapy
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Development of chromatographic and mass spectrometry conditions for untargeted lipidomic analysis of human breast milk
PublikacjaHuman breast milk (HBM) is a complex biofluid containing components which are essential for the proper growth of the newborn (for example nutrients such as carbohydrates, proteins, lipids) and also bioactive substances. According to the literature, most of studies involving HBM nutrients investigations focused essentially on the determination of proteins. The molecular composition of lipids in HBM is not well known as the protein...
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Decisional DNA for modeling and reuse of experiential clinical assessments in breast cancer diagnosis and treatment
PublikacjaClinical Decision Support Systems (CDSS) are active knowledge resources that use patient data to generate case specific advice. The fast pace of change of clinical knowledge imposes to CDSS the continuous update of the domain knowledge and decision criteria. Traditional approaches require costly tedious manual maintenance of the CDSS knowledge bases and repositories. Often, such an effort cannot be assumed by medical teams, hence...
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Active dynamic thermography method for TRAM flap blood perfusion mapping in breast reconstruction
PublikacjaThis paper presents the new method of the transverse rectus abdominis musculocutaneous flap blood perfusion mapping based on the active dynamic thermography. The method is aimed at aiding a surgeon during breast reconstruction procedure. A pair of dTnorm and t90_10 parameters were used as parametric image descriptors of the flap blood perfusion. The method was tested on 38 patients that were subjected to breast reconstruction procedure....
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Methylene Blue Near-Infrared Fluorescence Imaging in Breast Cancer Sentinel Node Biopsy
PublikacjaIntroduction: Fluorescence-based navigation for breast cancer sentinel node biopsy is a novel method that uses indocyanine green as a fluorophore. However, methylene blue (MB) also has some fluorescent properties. This study is the first in a clinical series presenting the possible use of MB as a fluorescent dye for the identification of sentinel nodes in breast sentinel node biopsy. Material and methods: Forty-nine patients with...
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Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
PublikacjaIncreased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...
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Human breast milk concentration of neopterin at various stages of lactation and during a single feeding
PublikacjaThe aim of this work was to determine the physiological level of neopterin in human breast milk, and to study its variability depending on the duration of a single feeding and the lactation stage. Breast milk samples from 74 women were collected between 2 and 4 days after delivery, and at 15, 30, and 90 days after delivery. Additionally, breast milk samples from eight women were collected before and after 7 and 15 min of breastfeeding....
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Analysis of transient thermal processes for improved visualization of breast cancer using IR imaging.
PublikacjaPrzedstawiono analizę możliwości i ograniczeń metod termograficznych w diagnostyce nowotworów piersi. Przeanalizowane termiczne modele numeryczne piersi z nowotworem pokazują, iż zastosowanie nowej metody aktywnej termografii dynamicznej z termicznym wymuszeniem zewnętrznym, może znacząco poprawić skuteczność wykrywania nowotworów piersi we wczesnym stadium ich rozwoju . Pokazano również wyniki badania klinicznego pacjentki...
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Short clinically-based prediction model to forecast transition to psychosis in individuals at clinical high risk state
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Impact of Investments and R&D Costs in Renewable Energy Technologies on Companies’ Profitability Indicators: Assessment and Forecast
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Precise Evaluation of Gas–Liquid Two-Phase Flow Pattern in a Narrow Rectangular Channel with Stereology Method
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Accuracy improvement of the prestressed concrete structures precise geometry assessment by use of bubble micro-sampling algorithm
PublikacjaPrestressed concrete structures are well-known technology for a vast period, but nevertheless, this very technology is a leading solution, currently used in construction industry. Prestressed concrete structures have a huge advantage over conventional methods because it uses the properties of concrete in a very efficient way. The main idea behind this technology is to introduce into the cross-section of the structure, the internal...
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Precise Bathymetry as a Step Towards Producing Bathymetric Electronic Navigational Charts for Comparative (Terrain Reference) Navigation
PublikacjaBathymetric Electronic Navigational Charts (bENCs) contain only bathymetry data and can be used in applications such as underwater positioning, dredging and piloting. According to International Hydrographic Organization (IHO) standard S-57, Electronic Navigational Charts (ENCs) contain depth information with pure density of depth contours. Typical depth contours encoded by Hydrographic Offices are limited to 2, 5, 10 and 20 m....
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Results of the application of tropospheric corrections from different troposphere models for precise GPS rapid static positioning
PublikacjaIn many surveying applications, determination of accurate heights is of significant interest. The delay caused by the neutral atmosphere is one of the main factors limiting the accuracy of GPS positioning and affecting mainly the height coordinate component rather than horizontal ones. Estimation of the zenith total delay is a commonly used technique for accounting for the tropospheric delay in static positioning. However, in the...
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Biological effects in photodynamic treatment combined with electropermeabilization in wild and drug resistant breast cancer cells
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A different methylation profile of circadian genes promoter in breast cancer patients according to clinicopathological features
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The effect of cabbage juice and its active components on transcription factor Nrf2 in breast cell lines
PublikacjaObniżenie zagrożenia chorobami nowotworowymi w przypadku diety bogatej w kapustę wiąże się ze zdolnością bioaktywnych związków tego warzywa do indukowania enzymów ochronnych 2. fazy będacych pod kontrolą czynnika transkrypcyjnego Nrf2. Zbadano wpływ soków z kapusty na poziom Nrf2 w komórkach unieśmiertelnionych i nowotworowych linii odpowiednio MCF10A i MCF-7. W obu przypadkach obserwowano wzrost poziomu tego czynnika oraz jego...