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Wyniki wyszukiwania dla: oligopeptide uptake
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Oligopeptide antifungals are exceptionally active against multidrug-resistant yeast
PublikacjaPermeazy peptydowe w komórkach drożdżowych są zdolne do transportu do wnętrza komórek oligopeptydów, zawierających w swojej strukturze niebiałkowe aminokwasy o właściwościach przeciwgrzybowych. Wśród szerokiego wachlarza tego rodzaju związków przebadanych pod względem aktywności biologicznej na wielolekoopornych komórkach drożdżowych, zaobserwowano liczna grupę, wykazującą zwiększoną aktywność względem komórek eksprymujących transportery...
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Transport deficiency is the molecular basis of Candida albicans resistance to antifungal oligopeptides
Publikacja(FMDP), an inhibitor of glucosamine-6-phosphate synthase, exhibited growth inhibitory activity against Candida albicans, with minimal inhibitory concentration values in the 0.05–50 mg/L range. Uptake by the peptide permeases was found to be the main factor limiting an anticandidal activity of these compounds. Di- and tripeptide containing FMDP (F2 and F3) were transported by Ptr2p/Ptr22p peptide transporters (PTR) and FMDP-containing...
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Peptide Permeases in Candida albicans
PublikacjaAims: The aim of this work was to characterize oligopeptide uptake in Candida albicans mutants in which the genes encoding putative peptide permeases were selectively disrupted. Initial velocities of transport of model oligopeptides, (Ala)2, (Ala)3, (Ala)4, and sensitivity of mutants to antifungal oligopeptides containing N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP) were determined and compared to those of the wild-type...
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Enhanced susceptibility to antifungal oligopeptides in yeast strains overexpressing ABC multidrug efflux pumps
PublikacjaPorównano podatność na działanie związków przeciwgrzybowych o strukturze oligopeptydowej oraz aminokwasowej szczepów Saccharomyces cerevisiae z usuniętymi genami kodującymi białka oporności wielolekowej oraz transformantów tych szczepów, zawierających geny CDR1, CDR2 lub MDR1, kodujące główne pompy wielolekowe Candida albicans. Rekombinowane szczepy nadprodukujące białka Cdr1p i Cdr2p wykazywały zwiększoną wrażliwość na wszystkie...
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Study on hydrogen uptake of functionalized carbon nanotubes
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Variation in global uptake of the Surgical Safety Checklist
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Cellular uptake of biotransformed graphene oxide into lung cells
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Water uptake analysis of acceptor-doped lanthanum orthoniobates
PublikacjaIn this work, lanthanum orthoniobates doped with either antimony, calcium, or both have been synthesized and studied. The water uptake of the investigated materials has been analyzed by means of thermogravimetric studies. The results show the difference between the thermodynamics of hydration between the lanthanum orthoniobate system and other proton conducting ceramics. The relation between the water uptake and effective acceptor...
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Uptake and Release of Double‐Walled Carbon Nanotubes by Mammalian Cells
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Mesoporous silica nanoflakes – Biocompatibility, cellular uptake and drug transport
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The biological role of prolyl oligopeptidase and the procognitive potential of its peptidic inhibitors from food proteins
PublikacjaProlyl oligopeptidase (POP) is a conserved serine protease belonging to proline-specific peptidases. It has both enzymatic and non-enzymatic activity and is involved in numerous biological processes in the human body, playing a role in e.g., cellular growth and differentiation, inflammation, as well as the development of some neurodegenerative and neuropsychiatric disorders. This article describes the physiological and pathological...
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Evaluating the antibacterial activity of muramyl dipeptide derivatives, retro-tuftsin derivatives, and anthraquinone oligopeptides against a range of pathogenic bacteria
PublikacjaSearch for new and efficient antibiotic is crucial because of microbial drug resistance and problems with side effects of the administered medication. In this study, we evaluate the in vitro microbiological activity of muramyl dipeptide derivatives, retro-tuftsin derivatives (i.e., tuftsin with reversed amino acid sequences), and combinations of retro-tuftsin derivatives with substituted anthraquinones. The potency of the investigated...
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Imprinted polymer particles for iron uptake: Synthesis, characterization and analytical applications
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Size-Dependent in Vitro Biocompatibility and Uptake Process of Polymeric Carbon Nitride
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Water uptake and energetics of the formation of barium zirconate based multicomponent oxides
PublikacjaA group of multi-component oxides based on BaZrO3 have been prepared using a solid-state reaction method and examined in terms of their water uptake and thermodynamics of formation. Depending on the type and amount of acceptor substitution, the synthesized compounds exhibit various proton defect concentrations, reaching up to 0.2 mol/mol for a compound containing 10 different elements in the B-sublattice, where 50% of them are...
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Structural Properties and Water Uptake of SrTi1−xFexO3−x/2−δ
PublikacjaIn this work, Fe-doped strontium titanate SrTi1−xFexO3−x/2−δ, for x = 0–1 (STFx), has been fabricated and studied. The structure and microstructure analysis showed that the Fe amount in SrTi1−xFexO3−x/2−δ has a great influence on the lattice parameter and microstructure, including the porosity and grain size. Oxygen nonstoichiometry studies performed by thermogravimetry at different atmospheres showed that the Fe-rich compositions...
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Uptake, tissue distribution, and metabolism of malachite green in the channel catfish (Ictalurus punctatus)
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Removal of diphenols using pine biochar. Kinetics, equilibrium, thermodynamics, and mechanism of uptake
PublikacjaThermal pyrolysis synthesized activated biochar from the Pinus elliottii sawdust (PS) at 600° C. The obtained activated biochar (PB600) was used for the removal of three diphenols, catechol (CAT), resorcinol (RES), and hydroquinone (HYD), which are utilized mainly in different industries. The PB600 was characterized by several analytical techniques. The BET surface area of 1473 m2.g−1 and a total pore volume of 0.707 cm3 g−1 was...
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Water uptake in protective organic coatings and its reflection in measured coating impedance
PublikacjaWater uptake in commercially available epoxy coating on mild steel using impedance spectroscopy and gravimetry was studied. The water content in the coating was determined using the Brasher-Kingsbury equation and various methods of coating capacitance calculation used in the literature. The obtained results were compared with reference gravimetric data. An overestimation of values obtained from impedance data in relation to gravimetric...
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Mapping of the Covid-19 Vaccine Uptake Determinants From Mining Twitter Data
PublikacjaOpinion polls on vaccine uptake clearly show that Covid-19 vaccine hesitancy is increasing worldwide. Thus, reaching herd immunity not only depends on the efficacy of the vaccine itself, but also on overcoming this hesitancy of uptake in the population. In this study, we revealed the determinants regarding vaccination directly from people’s opinions on Twitter, based on the framework of the 6As taxonomy. Covid-19 vaccine acceptance...
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Update in Anaesthesia
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Dental update
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Thrombosis Update
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Better Late Than Never: Predictors of Delayed COVID-19 Vaccine Uptake in Poland
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Study on size effect of the silica nanospheres with solid core and mesoporous shell on cellular uptake
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The impact of slowly biodegradable organic compounds on the oxygen uptake rate in activated sludge systems
PublikacjaThe hydrolysis process of slowly biodegradable substrate (Xs) have impact on the efficiencies of nutrient removal in activated sludge systems. Measurement of OUR and corresponding COD is accepted as a very useful tool to reflect the consumption of biodegradable substrates. The influence of the readily biodegradable substrate (Ss) in biological wastewater treatment systems has been extensively investigated, but little is known about...
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The impact of slowly biodegradable organic compounds on the oxygen uptake rate in activated sludge systems
PublikacjaThe hydrolysis process of slowly biodegradable substrate (Xs) have impact on the efficiencies of nutrient removal in activated sludge systems. Measurement of OUR and corresponding COD is accepted as a very useful tool to reflect the consumption of biodegradable substrates. The influence of the readily biodegradable substrate (Ss) in biological wastewater treatment systems has been extensively investigated, but little is known about...
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Influence of Dimerization of Lipopeptide Laur-Orn-Orn-Cys–NH2 and an N-terminal Peptide of Human Lactoferricin on Biological Activity
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Comparative in vitro study of single and four layer graphene oxide nanoflakes — Cytotoxicity and cellular uptake
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Systematic Water Uptake Energetics of Yttrium-Doped Barium Zirconate—A High Resolution Thermochemical Study
PublikacjaA combination of surface area analyzer and microcalorimetry was employed to investigate the in situ water uptake energetics and the mechanism of proton incorporation in yttrium-doped barium zirconate in the temperature range 200–400 °C. The BaZr1–xYxO3 solid solutions are made with variable yttrium content (x = 10, 20, and 30 mol %) by a controlled oxidant-peroxo synthesis method. The water uptake increases as the partial pressure...
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Photodynamic Inactivation of Candida albicans with Imidazoacridinones: Influence of Irradiance, Photosensitizer Uptake and Reactive Oxygen Species Generation
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Influence of iron content on water uptake and charge transport in BaCe0.6Zr0.2Y0.2−xFexO3−δ triple-conducting oxides
PublikacjaIn this work, we studied the BaCe0.6Zr0.2Y0.2−xFexO3−δ system which belongs to the triple-conducting oxides (TCOs) group. The electrochemical properties of BaCe0.6Zr0.2Y0.2−xFexO3−δ were investigated using electrochemical impedance spectroscopy (EIS) and the water uptake was analyzed using thermogravimetry (TG). All investigated materials exhibited water uptake, with proton concentration increasing with decreasing iron content....
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Water uptake kinetics and electrical transport in BaCe0.6Zr0.2Y0.1M0.1O3−δ (M = Tb, Pr, Fe) protonic conductors
PublikacjaBaCe0.6Zr0.2Y0.1M0.1O3−d (M = Fe, Pr, Tb) is a mixed conducting oxide in which three mobile charge carriers – oxygen ion, electron/hole, and protonic defects – are present. These types of materials have gained much interest as electrode materials for protonic ceramic fuel cells (PCFCs) and protonic ceramic electrolysis cells (PCECs). In this study, the water uptake and oxygen transport properties of different BaCe0.6Zr0.2Y0.1M0.1O3−d...
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Motors of influenza vaccination uptake and vaccination advocacy in healthcare workers: A comparative study in six European countries
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Evaluation and behaviour of slowly biodegradable substrate on mathematical modelling of oxygen uptake rate in activated sludge systems
PublikacjaThe effect of the readily biodegradable (Ss) fraction in activated sludge systems has been extensively investigated, but only minor information can be found about the effect of Xs on OUR in activated sludge systems. The aim of this study was to determine the evaluation and behaviour of Xs on mathematical modelling of OUR using ASM2d and its modification. The essential study was divided into two major parts: experimental investigation...
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Structure and water uptake in BaLnCo2O6−δ (Ln =La, Pr, Nd, Sm, Gd, Tb and Dy)
PublikacjaThe structure of BaLnCo2O6-δ (Ln =La, Pr, Nd, Sm, Gd, Tb and Dy) was studied by the means of synchrotron radiation powder X-ray diffraction, neutron powder diffraction and Transmission Electron Microscopy (TEM), while water uptake properties were analysed with the use of thermogravimetry (TG) and water adsorption isotherms. The structure refinement revealed that the dominant phase in all compositions was orthorhombic with an ordering...
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In vivo phytotoxic effect of yttrium-oxide nanoparticles on the growth, uptake and translocation of tomato seedlings (Lycopersicon esculentum)
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Ptaki Śląska
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Sustainable Conversion of Mixed Plastics into Porous Carbon Nanosheets with High Performances in Uptake of Carbon Dioxide and Storage of Hydrogen
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Interactive effects of vanadium and phosphorus on their uptake, growth and heat shock proteins in chickpea genotypes under hydroponic conditions
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Bioavailability evaluation, uptake of heavy metals and potential health risks via dietary exposure in urban-industrial areas
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HUMAN REPRODUCTION UPDATE
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Medico-Legal Update
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Update a simple hypoplastic constitutive model
PublikacjaW artykule omówiono uproszczona formę hipoplastycznego konstytutywnego prawa materiałowego do opisu zachowania się materiałów granulowanych. Wykonano symulacje testów elementów i porównano wyniki z doświadczeniami.
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Photodynamic Inactivation of Bacteria with Porphyrin Derivatives: Effect of Charge, Lipophilicity, ROS Generation, and Cellular Uptake on Their Biological Activity In Vitro
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Numerical modeling of PFAS movement through the vadose zone: Influence of plant water uptake and soil organic carbon distribution
PublikacjaIn this study, we investigated the effects of soil organic carbon (SOC) distribution and water uptake by plant roots on PFAS movement in the vadose zone with a deep groundwater table under temperate, humid climate conditions. Two series of numerical simulations were performed with the HYDRUS computer code, representing the leaching of historical PFOS contamination and the infiltration of water contaminated with PFOA, respectively. We...
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Quantum Dots as a Good Carriers of Unsymmetrical Bisacridines for Modulating Cellular Uptake and the Biological Response in Lung and Colon Cancer Cells
PublikacjaNanotechnology-based drug delivery provides a promising area for improving the efficacy of cancer treatments. Therefore, we investigate the potential of using quantum dots (QDs) as drug carriers for antitumor unsymmetrical bisacridine derivatives (UAs) to cancer cells. We examine the influence of QD–UA hybrids on the cellular uptake, internalization (Confocal Laser Scanning Microscope), and the biological response (flow cytometry...
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Silicon occurrence, uptake, transport and mechanisms of heavy metals, minerals and salinity enhanced tolerance in plants with future prospects: A review
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Electrical conductivity relaxation measurements - water uptake of BaCe0.6Zr0.2Y0.1Tb0.1O3-δ
Dane BadawczeFor Electrical Conductivity Relaxation (ECR) measurements, platinum reversible electrodes were applied in a four-probe arrangement and the BaCe0.6Zr0.2Y0.1Tb0.1O3-δ sample was measured in the ProboStat™ measurement system. The ECR measurements were performed in air in the temperature range of 450-800 ℃ after switching water partial pressure between...
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Interactive assessment of lignite and bamboo-biochar for geochemical speciation, modulation and uptake of Cu and other heavy metals in the copper mine tailing
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