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Search results for: activity in the older age
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Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity.
PublicationThe development of a new drug requires knowledge about its metabolic fate in a living organism, regarding the comprehensive assessment of both drug therapeutic activity and toxicity profiles. Electrochemistry (EC) coupled with mass spectrometry (MS) is an efficient tool for predicting the phase I metabolism of redox-sensitive drugs. In particular, EC/MS represents a clear advantage for the generation of reactive drug transformation...
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Comparative Analysis of Metabolic Variations, Antioxidant Profiles and Antimicrobial Activity of Salvia hispanica (Chia) Seed, Sprout, Leaf, Flower, Root and Herb Extracts
PublicationThe purpose of this study was to evaluate the phytochemical profiles of the seeds, sprouts, leaves, flowers, roots and herb of Salvia hispanica and to demonstrate their significant contribution to antioxidant and antimicrobial activities. Applied methods were: HPLC-DAD coupled with post-column derivatization with ABTS reagent, untargeted metabolomics performed by LC-Q-Orbitrap HRMS, and two-fold micro-dilution broth method, which...
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Heterogeneous oxidation of highly boron-doped diamond electrodes and its influence on the surface distribution of electrochemical activity
PublicationThe electrochemical active surface area (EASA) of polycrystalline boron-doped diamond (BDD) electrodes is heterogeneous and can be affected by numerous factors. There is a strong need for proper consideration of BDD heterogeneity in order to improve this material's range of application in electrochemistry. Localized changes in surface termination due to the influence of oxidation agent result in increased surface resistance. The...
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Effect of irradiation intensity and initial pollutant concentration on gas phase photocatalytic activity of TiO2 nanotube arrays
PublicationWell-organized TiO2 nanotube arrays were fabricated via one-step anodization process. The as-prepared TiO2 nanotubes were characterized by X-ray powder diffractometry (XRD), X-ray photoelectron spectroscopy (XPS), diffuse reflectance spectroscopy (DRS) and scanning electron microscopy (SEM). Photocatalytic activity of obtained photocatalyst was studied in reaction of toluene degradation in the gas phase using low powered and low...
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Molecular geometry and optical activity of helically chiral N-nitrosamines derived from 1,2,3,4-tetrahydro- and 1,2,3,4,7,8,9,10-octahydro-1,10-phenanthroline
PublicationX-ray crystallographic analysis of the title N-nitrosamines revealed that they assume helical conformations in the solid state. Nitrosamines 1b and 2b were resolved by inclusion crystallization with optically active diols (TADDOLs). The absolute configuration of the guest molecules in the complexes 1b·3b and 2b·3b was assigned as M. The optical activity of the resolved compounds is manifested by their solid state CD spectra, which...
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S09 Insights into the development of the physical activity environment policy index, a tool for benchmarking implementation of public policies to create healthy physical activity policy environments
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Introduction of Pro and Its Analogues in the Conserved P1 Position of Trypsin Inhibitor SFTI-1 Retains Its Inhibitory Activity
PublicationA number of monocyclic SFTI-1 analogues modified in the conserved inhibitor P1 position by Pro, its L-hydroxyproline (Hyp) derivative as well as mimetics with different ring size were synthesized by the solid-phase method. Replacement of Ser6 by Pro, Hyp, and a four-member ring, L-azetidine-2-carboxylic acid (Aze), retained trypsin or chymotrypsin inhibitory activity. The determined association equilibrium constants of these analogues...
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Evaluation of Gas Chromatography Stationary Phases Based on Morpholinium Ionic Liquids by McReynolds Constants and Activity Coefficients at Infinite Dilution
PublicationIn this work, four ionic liquids (ILs) based on the N-alkyl-N-methylmorpholinium cation ([Mor1,R], in which R = 2, 4, 8, or 10) and bis (trifluoromethanesulfonyl)imide anion were synthesized. Using GLC, a number of parameters describing the sorption properties of the investigated ILs were determined. The values of Kovats indices, McReynolds constants, and activity coefficients at infinite dilution were the basis for the evaluation...
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ECG measurement from the hand with standing - hands resting on the device - Woman 27 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the table top - Man 29 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the armrests of the chair - Woman 27 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the armrests of the chair - Woman 49 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with standing - hands resting on the device - Man 29 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the table top - Woman 27 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with standing - hands resting on the device - Woman 49 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the armrests of the chair - Man 29 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the table top - Woman 49 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with standing - hands resting on the device - Man 30 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the armrests of the chair - Man 30 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the table top - Woman 30 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with standing - hands resting on the device - Woman 30 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the armrests of the chair - Woman 30 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with standing - hands resting on the device - Man 53 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the table top - Man 30 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the armrests of the chair - Man 53 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the table top - Man 53 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with standing - hands resting on the device - Woman 24 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the table top - Woman 24 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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ECG measurement from the hand with elbows resting on the armrests of the chair - Woman 24 age
Open Research DataThe data set shows the measurements of the ECG signal from the hand made with the use of the proprietary measuring system, based on the AD8232 and STM32 chips. Thanks to such a constructed device, it is possible to measure the ECG signal in a non-standard way - from the hand. The results show the ECG signal for a specific hand and forearm position relative...
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Environmentally Friendly Fabrication of High-Efficient Fe-ZnO/Citric Acid-Modified Cellulose Composite and the Enhancement of Photocatalytic Activity in the Presence of H2O2
PublicationIn the present study, a novel Fe-ZnO/citric acid-modified cellulose composite (x%Fe-ZnOy% CAC) was synthesized using an environmentally friendly hydrothermal method. The obtained samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), UV−vis diffuse reflectance spectroscopy (DRS), Fourier transform infrared spectroscopy (FTIR), nitrogen physisorption, and electrochemical and photocurrent density...
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Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a dimericcRGD Peptide for Targeted Imaging of αVβ3 Integrin Activity
PublicationCyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α V β3 integrin. We report the synthesis, chemical characterization, and biological evaluation of two novel dimeric cyclic RGD-based molecular probes for the targeted imaging of α V β3 activity (a radiolabeled version, 64Cu-NOTA-PEG4-cRGD2, for PET imaging, and a fluorescent version, FITC-PEG4-cRGD2, for in...
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Ontological Modeling for Contextual Data Describing Signals Obtained from Electrodermal Activity for Emotion Recognition and Analysis
PublicationMost of the research in the field of emotion recognition is based on datasets that contain data obtained during affective computing experiments. However, each dataset is described by different metadata, stored in various structures and formats. This research can be counted among those whose aim is to provide a structural and semantic pattern for affective computing datasets, which is an important step to solve the problem of data...
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Photocatalytic degradation and pollutant-oriented structure-activity analysis of carbamazepine, ibuprofen and acetaminophen over faceted TiO2
PublicationPhotocatalytic degradation of carbamazepine, ibuprofen, acetaminophen and phenol was studied in the presence of anatase photocatalyst, exposing three different crystal facets in the majority of {0 0 1}, {1 0 0} or {1 0 1}. It was found that octahedral anatase particles exposing {1 0 1} facets allow to achieve the best degradation and mineralization of all persistent organic pollutants. This confirms that the previous findings,...
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Impact of the Alkyl Side Chains of Cations and Anions on the Activity and Renaturation of Lysozyme: A Systematic Study Performed Using Six Amino‐Acid‐Based Ionic Liquids
PublicationThe impact of the structure of ionic liquid on the activity and renaturation of lysozyme from the hen egg white (HEWL) was investigated. A set of six ionic liquids based on morpholinium cation and N-acylated amino acids as anions were exploited. The matrix used was based on two homologous series: one with N-acetyl-L-valinate [Val] as a common anion and morpholinium cation with a different number of carbon atoms in the n-alkyl chain...
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Enhanced Activity of P4503A4 and UGT1A10 Induced by Acridinone Derivatives C-1305 and C-1311 in MCF-7 and HCT116 Cancer Cells: Consequences for the Drugs’ Cytotoxicity, Metabolism and Cellular Response
PublicationActivity modulation of drug metabolism enzymes can change the biotransformation of chemotherapeutics and cellular responses induced by them. As a result, drug-drug interactions can be modified. Acridinone derivatives, represented here by C-1305 and C-1311, are potent anticancer drugs. Previous studies in non-cellular systems showed that they are mechanism-based inhibitors of cytochrome P4503A4 and undergo glucuronidation via UDP-glucuronosyltranspherase...
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Metodyka wdrażania Zarządzania Wiekiem w Przedsiebiorstwach i Organizacjach Publicznych uczestniczących w projekcie Best Agers Lighthouses
PublicationCelem artykułu jest przedstawienie metodyki wdrażania zarządzania wiekiem w małych i średnich przedsiębiorstwach i organizacjach publicznych Regionu Morza Bałtyckiego, opracowanej w ramach projektu Best Agers Lighthouses –Strategic Age Management for SME in the Baltic Sea Region. W artykule opisano m.in. sekwencję kluczowych działań podjętych podczas procesu wdrażania oraz strukturę podmiotową wspierającą współpracę uczestników...
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Antifungal activity of propolis extracts, screening and kinetic data
Open Research DataThis folder contains results of our studies aiming in determination of antifungal potential of ethanolic extracts of propolis and components of this product. In details, MIC, MFC values were determined and kill time assays were performed.
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The photocatalytic activity of MoS2 electrodes under sunlight illumination
Open Research DataThis dataset contains the results of the photocatalytic activities of the MoS2 and MoS2 modified by SnO2 were assessed through the photocatalytic reduction of Cr6+ under the sunlight illumination. In the experiment, 20 mg of the catalyst was distributed in the K2Cr2O7 aqueous solution (50 mL, 100 mg•L-1). The mixed solution was stirred for 30 min to...
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Synthesis and biological activity of mycophenolic acid-amino acid derivatives
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The Total Efficiency of Teaching Activity of Polish Higher Education Institutions
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A Novel Method for the Combined Photocatalytic Activity Determination and Bandgap Estimation
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A Biofeedback System that Uses the Game to Study Electrical Muscle Activity
PublicationThe aim of this project was to design a system that will allow performing repetitive muscle exercises using a biofeedback device. It is supposed to enhance the motivation and attractiveness of the performed tasks thanks to an interactive game developed for mobile devices with the Android operating system. The built-in calibration mechanisms enable the users to play a game that is independent of their abilities which evens out the...
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The neuroprotective activity of new phenylalanine-based AMPA receptor antagonists
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Hybrid nanolayers of star polymers and silver nanoparticles with antibacterial activity
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Photocatalytic activity and OH radical formation on TiO2 in the relation to crystallinity
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TiO2 Nanoparticles with High Photocatalytic Activity Under Visible Light
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Manganese dioxide (MnO2) nanoparticles influence on the nitrification and anammox activity
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Visible light activity and photoelectrochemical properties of nitrogen-doped TiO2.
PublicationFotokatalizatory TiO2 domieszkowane azotem zostały zsyntetyzowane z propanolanu tytanu (IV) lub chlorku tytanu (IV) i tiomocznika. Żółte proszki otrzymane po ogrzewaniu w temperaturach 400-600 st.C fotokatalizowały mineralizację 4-chlorofenolu w zakresie światła widzialnego (delta większe lub równe 455nm. W odróżnieniu od uprzednio opublikowanych wyników, zsyntetyzowane fotokatalizatory nie zawierały siarki, lecz zamiast tego azot...
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Photocatalytic activity and surface properties of carbon-doped titanium dioxide
PublicationTiO2 domieszkowany węglem otrzymano poprzez hydrolizę izopropanolanu tytanu(IV) i kalcynację w 350ºC w atmosferze powietrza przez 2h. Przeprowadzone badania wykazały, że fenol (0.21 mM) jest efektywnie degradowany w fazie wodnej, w obecności otrzymanego fotokatalizatora oraz światła z zakresu widzialnego (λ>400 nm). Pole powierzchni właściwej otrzymanego C-TiO2 wynosiło około 127 m2/g, fotokatalizator absorbuje światło z zakresu...
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Antimicrobial and surface activity of 1-alkyl-3-methylimidazolium derivatives
PublicationWiedza na temat zależności struktura-aktywność umożliwia projektowanie i syntezę nowych kationowych związków amfifilowych ze zoptymalizowaną aktywnością antymikrobową na rzecz przyszłego rozwoju nowych środków dezynfekujących, sanityzujących czy konserwujących. Potrzeba projektowania i identyfikowania nowych związków posiadających właściwości przeciwbakteryjne jest rezultatem pojawienia się bardziej odpornych mikroorganizmów w...