Search results for: NERVE SHEATH TUMORS
-
Effects of perineural administration of ropivacaine combined with perineural or intravenous administration of dexmedetomidine for sciatic and saphenous nerve blocks in dogs
Publication -
Radiochemical Synthesis and Evaluation of Novel Radioconjugates of Neurokinin 1 Receptor Antagonist Aprepitant Dedicated for NK1R-Positive Tumors
Publication -
A targeted mass spectrometry immunoassay to quantify osteopontin in fresh-frozen breast tumors and adjacent normal breast tissues
Publication -
Effects of acute and long-term slow breathing exercise on muscle sympathetic nerve activity in untreated male patients with hypertension
Publication -
Expression of zinc finger transcription factors (ZNF143 and ZNF281) in serous borderline ovarian tumors and low-grade ovarian cancers
Publication -
Expression of selected epithelial–mesenchymal transition transcription factors in serous borderline ovarian tumors and type I ovarian cancers
Publication -
Coincidental Detection of Gastrointestinal Stromal Tumors During Laparoscopic Bariatric Procedures—Data and Treatment Strategy of a German Reference Center
Publication -
Identification of High-Risk Stage II Colorectal Tumors by Combined Analysis of the NDRG1 Gene Expression and the Depth of Tumor Invasion
Publication -
KRAS mutation testing in borderline ovarian tumors and low-grade ovarian carcinomas with a rapid, fully integrated molecular diagnostic system
Publication -
Molecular Heterogeneity of Papillary Thyroid Cancer: Comparison of Primary Tumors and Synchronous Metastases in Regional Lymph Nodes by Mass Spectrometry Imaging
Publication -
The associations between serum VEGF, bFGF and endoglin levels with microvessel density and expression of proangiogenic factors in malignant and benign ovarian tumors
Publication -
Expression-based decision tree model reveals distinct microRNA expression pattern in pediatric neuronal and mixed neuronal-glial tumors
Publication -
Analysis of pharmacotherapy regimen and costs in patients with drug-resistant epilepsy following vagus nerve stimulation therapy: a single-center study (Poland)
Publication -
Giant cell tumor of tendon sheath, NOS - Female, 61 - Tissue image [6260730021897531]
Open Research DataThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Giant cell tumor of tendon sheath, NOS - Female, 67 - Tissue image [626073002189481]
Open Research DataThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Automated Analysis of Images from Confocal Laser Scanning Microscopy Applied to Observation of Calcium Channel Subunits in Nerve Cell Model Line Subjected Electroporation and Calcium
Publication -
LanroNET, a non-interventional, prospective study to assess the resource utilization and cost of lanreotide autogel 120 mg in Polish patients with neuroendocrine tumors – results of interim analysis
Publication -
Corrigendum to “Rapid PD-L1 detection in tumors with PET using a highly specific peptide” [Biochemical and Biophysical Research Communications 483/1 (2017) 258–263]
Publication -
Automatic Detection of Nerves in Confocal Corneal Images with Orientation-Based Edge Merging
PublicationThe paper presents an algorithm for improving results of automatic nerve detections in confocal microscopy images of human corneal. The method is designed as a postprocessing step of regular detection. After the nerves are initially detected, the algorithms attempts to improve the results by filling unde-sired gaps between single nerves detections in order to correctly mark the entire nerve instead of only parts of it. This approach...
-
Connective and other soft tissue - Male, 54 - Tissue image [4130730006612131]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Connective and other soft tissue - Male, 54 - Tissue image [413073000661941]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Connective and other soft tissue - Male, 54 - Tissue image [4130730006613731]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Connective and other soft tissue - Male, 54 - Tissue image [4130730006615221]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Analytical method of determining dynamic properties of thermocouples used in measurements of quick – changing temperatures of exhaust gases in marine diesel engines
PublicationThe article presents selected issues of mathematical modeling of heat exchange between the thermocouple and the exhaust gas flowing them, in unsteady conditions. On the way of energy balancing consideration of thermodynamic processes developed differential equations describing the dynamic properties for three versions of the design sheathed thermocouples: with weld isolated from the sheath, with weld welded the sheath and with...
-
Deep convolutional neural network for predicting kidney tumour malignancy
PublicationPurpose: According to the statistics, up to 15-20% of removed solid kidney tumors turn out to be benign in postoperative histopathological examination, despite having been identified as malignant by a radiologist. The aim of the research was to limit the number of unnecessary nephrectomies of benign tumors. Methods or Background: We propose a machine-aided diagnostic system for kidney...
-
Analysis of unsteady flow forces on the thermowell of steam temperature sensor
PublicationIn this paper, 3D numerical analysis of unsteady flow forces acting on the measuring sheath of steam temperature is presented. According to that purpose, the CFD (Computation Fluid Dynamic [1]) approach has been used. The nonstationary of fluid acting on the measuring sheath such as: Strouhal frequency, amplitude of pressure, structure of vortex, peak of pressure, field of pressure, field of velocity etc. are studied analytically...
-
Analysis of Induced Voltages and Power Losses in High Voltage Power Cables for Selected Methods of Cables Sheaths Bonding
PublicationPower is increasingly supplied to city centres with 110 kV cable lines. This is a convenient way to supply power, and practically the only one possible in areas of dense urban development. A high-voltage cable contains a coaxial metallic sheath, in which in normal operation and in fault conditions (during short-circuits) significant line-to-earth voltages can be induced, which threatens electric shock and/or damage to the cable’s...
-
Laboratory research on the influence of swelling clay on the quality of borehole cementing and evaluation of clay-cutting wellbore tool prototype
PublicationSwelling clay phenomenon is frequently observed during oil and gas drilling operations and has a significant impact on the quality of cementing procedure. Certain types of clayey minerals increase their volume in contact with water-based drilling fluids. After drilling is completed, borehole remains unsupported and filled with waterbased drilling fluids for several hours, before a casing string is inserted and secured with cement....
-
Enhancing Renal Tumor Detection: Leveraging Artificial Neural Networks in Computed Tomography Analysis
PublicationRenal cell carcinoma is one of the most common cancers in Europe, with a total incidence rate of 18.4 cases per 100 000 population. There is currently significant overdiagnosis (11% to 30.9%) at times of planned surgery based on radiological studies. The purpose of this study was to create an artificial neural network (ANN) solution based on computed tomography (CT) images as an additional tool to improve the differentiation of...
-
Wykorzystanie tomografii komputerowej przy analizie jakości zacementowania - migracja gazu
PublicationArtykuł przedstawia opis zjawiska znanego w wiertnictwie otworowym jako migracja gazu. Opisano główne przyczyny powstawania tego negatywnego zjawiska polegającego na przepływie gazów a także płynów w zaczynie cementacyjnym lub kamieniu cementowym. Przygotowano próbki imitujące zacementowany odcinek rur okładzinowych. Skupiono się na wykorzystaniu tomografii komputerowej, oraz analizie zrekonstruowanego trójwymiarowego obrazu, w...
-
Comparison of Selected Neural Network Models Used for Automatic Liver Tumor Segmentation
PublicationAutomatic and accurate segmentation of liver tumors is crucial for the diagnosis and treatment of hepatocellular carcinoma or metastases. However, the task remains challenging due to imprecise boundaries and significant variations in the shape, size, and location of tumors. The present study focuses on tumor segmentation as a more critical aspect from a medical perspective, compared to liver parenchyma segmentation, which is the...
-
Recent advances in 3D bioprinted tumor models for personalized medicine
PublicationCancerous tumors are among the most fatal diseases worldwide, claiming nearly 10 million lives in 2020. Due to their complex and dynamic nature, modeling tumors accurately is a challenging task. Current models suffer from inadequate translation between in vitro and in vivo results, primarily due to the isotropic nature of tumors and their microenvironment's relationship. To address these limitations, hydrogel-based 3D bioprinting...
-
New perspective on the in vivo use of cold stress dynamic thermography in integumental reconstruction with the use of skin-muscle flaps
PublicationAmong the problems encountered by plastic surgeons is the reconstruction of defects following tumors. One of the reconstructive options is TRAM flap. Despite that anatomy is well-explored, marginal flap necrosis may develop. To minimize complications imaging examinations was designed to determine the degree of flap perfusion. One of them is the thermographic examination.
-
Modelling of MV and HV Cable Lines
PublicationOverhead and cable lines are fundamental elements of power systems. Participation of cable lines is smaller and their percentage decreases as voltage is increased. HV cable lines are often built with the use of cables which are composed of coaxial metallic sheaths. Such cables are also often used in MV networks. The sheath may operate in different confgurations. In the case of Polish MV network the sheaths are earthed at both ends....
-
Regenerative Drug Discovery Using Ear Pinna Punch Wound Model in Mice
PublicationThe ear pinna is a complex tissue consisting of the dermis, cartilage, muscles, vessels, and nerves. Ear pinna healing is a model of regeneration in mammals. In some mammals, including rabbits, punch wounds in the ear pinna close spontaneously; in common-use laboratory mice, they remain for life. Agents inducing ear pinna healing are potential regenerative drugs. We tested the effects of selected bioactive agents on 2 mm ear pinna...
-
Electro-optical transducer based on indium-tin-oxide-coated optical fiber for analysis of ionized media
PublicationThe paper introduces a concept of an optical fiber based electro-optical transducer for monitoring of ionized media, such as low-temperature plasma. It utilizes optical fiber with a section of a core coated with tailored indium tin oxide (ITO) thin film and thus combines the optical phenomena of lossy-mode resonance (LMR) with the electrostatic probe. ITO is an optically transparent and electrically conductive material and if its...
-
Orbital blowout trauma occurring at the workplace – clinical, biomechanical and legal aspects
PublicationIntroduction and objective: Craniofacial injury at the workplace may lead to orbital blowout fractures. The aim of the study is the development of own numerical model of the eye orbit, assessment of the damage zones, and comparing them with clinical examinations. In addition, the current legal status of patients after injuries is presented Material and methods: In laboratory tests performed on bones collected from the upper and...
-
Ultrasound and Clinical Preoperative Characteristics for Discrimination Between Ovarian Metastatic Colorectal Cancer and Primary Ovarian Cancer: A Case-Control Study
PublicationThe aim of this study was to describe the clinical and sonographic features of ovarian metastases originating from colorectal cancer (mCRC), and to discriminate mCRC from primary ovarian cancer (OC). We conducted a multi-institutional, retrospective study of consecutive patients with ovarian mCRC who had undergone ultrasound examination using the International Ovarian Tumor Analysis (IOTA) terminology, with the addition of evaluating...
-
Inhibition of T-type calcium channel disrupts Akt signaling and promotes apoptosis in glioblastoma cells.
PublicationGlioblastoma multiforme (GBM) are brain tumors that are exceptionally resitant to both radio- and chemotherapy regimens and novel approaches to treatment are needed. T-type calcium channels are one type of low voltage-gated channel (LVCC) involved in embryonic cell proliferation and differentiation; however they are often over-expressed in tumors, including GBM. In this study, we found that inhibition of T-type Ca channels in GBM...
-
Future of medicine: personalized oncology
PublicationUnderstanding genetic and epigenetic mechanisms of tumorigenesis allows identifying many vital mutations affected the formation of various malignancies. This led to the discovery of a new therapeutic approach, based on molecular mechanisms in the world of medicine, which is called personalized medicine (PM). This review aims to outline the state of the art of the personalized medicine in treatment, taking into account anti-cancer...
-
Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublicationPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
-
Selected Methods for the Chemical Phosphorylation and Thiophosphorylation of Phenols
PublicationThis Focus Review gathers together a selection of methods for the chemical phosphorylation of phenols that employ three‐ and four‐coordinate phosphorus compounds. Phosphorylated scaffolds can exhibit enhanced properties compared to their non‐phosphorylated analogues, such as increased biological activity and increased/decreased solubility; as such, phosphorus compounds have gained more and more interest in organic and medicinal...
-
Analysis of dynamics of a map-based neuron model via Lorenz maps
PublicationModeling nerve cells can facilitate formulating hypotheses about their real behavior and improve understanding of their functioning. In this paper, we study a discrete neuron model introduced by Courbage et al. [Chaos 17, 043109 (2007)], where the originally piecewise linear function defining voltage dynamics is replaced by a cubic polynomial, with an additional parameter responsible for varying the slope. Showing that on a large...
-
Recent trends in determination of neurotoxins in aquatic environmental samples
PublicationAnatoxins, saxitoxins, ciguatoxins, beta-N-methylamino-l-alanine and its isomers are groups of neurotoxins which have a highly specific effect on the nervous system of animals, including humans, by interfering with the transmission of nerve impulses. In order to assess the human exposure to these neurotoxins, selective, interlaboratory-validated analytical methods are being developed to facilitate obtaining reliable results on...
-
Nanodiamonds Doped with Manganese for Applications in Magnetic Resonance Imaging
PublicationNanodiamonds (NDs) are emerging with great potential in biomedical applications like biomarking through fluorescence and magnetic resonance imaging (MRI), targeted drug delivery, and cancer therapy. The magnetic and optical properties of NDs could be tuned by selective doping. Therefore, we report multifunctional manganese-incorporated NDs (Mn-NDs) fabricated by Mn ion implantation. The fluorescent properties of Mn-NDs were tuned...
-
Mirosław Andrusiewicz prof. dr hab. n. med. i n. o zdr.
PeopleDiplomas, degrees conferred in specific areas ̶ Post-doctoral degree in medical sciences (doctor habilitated) (discipline: medical biology) December 4, 2017; Title of academic achievement: "Analysis of selected genes involved in the control of pathological changes in cells derived from internal female reproductive organs"; Poznan University of Medical Sciences, Faculty of Medicine II; re-viewers: Prof. Katarzyna Ziemnicka,...
-
Zastosowanie specjalnego uziemienia żył powrotnych w liniach kablowych SN
PublicationW artykule porównano metody uziemiania żył powrotnych kabli średniego napięcia. Głównym kryterium oceny poszczególnych rozwiązań było ograniczenie strat w przesyle energii elektrycznej oraz zapewnienie ochrony przeciwprzepięciowej osłon kabli. Na podstawie symulacji kabli zamodelowanych w programie CYMCAP i otrzymanych wyników obciążalności prądowej i strat w linii zaprezentowano metodę krzyżowania żył powrotnych (CB – cross-bonding...
-
Incomplete Cross-Bonding in the MV Line. Experience from the Operation of MV Single Cable Lines
PublicationCable lines are one of the basic components of power systems. Medium and high voltage cables mainly comprise a metallic sheath, which is concentric to the main core conductor. There are several operating schemes of such cable lines, which differ in the place of earthing of sheaths and the possible use of the sheaths and/or conductors crossing. The sheaths cross-bonding is typically done in two places of one cable line section,...
-
Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
PublicationElectrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...
-
Chloroacridine derivatives as potential anticancer agents which may act as tricarboxylic acid cycle enzyme inhibitors
PublicationThe chloroacridines affect biological forms of melanoma in different ways. Amelanotic (Ab) melanoma (with inhibited melanogenesis and higher malignancy) was particularly sensitive to the action of the chloroacridines. The Ab melanoma cells died through apoptosis and through death without caspase activation. Diminished activity of TAC enzymes was noticed among Ab melanoma cells together with ATP/NAD depletion, especially in the...