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Search results for: PSORIASIS GENETICS, GWAS, EPIGENETIC CHANGES, MIRNA
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Fast Algorithms for Identification of Time-Varying Systems with Both Smooth and Discontinuous Parameter Changes
PublicationThe problem of noncausal identification of a time-varying linear system subject to both smooth and occasional jump-type changes is considered and solved using the preestimation technique combined with the basis function approach to modeling the variability of system parameters. The proposed estimation algorithms yield very good parameter tracking results and are computationally attractive.
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Seabed Topography Changes in the Sopot Pier Zone in 2010–2018 Influenced by Tombolo Phenomenon
PublicationBathymetric surveys of the same body of water, performed at regular intervals, apart from updating the geospatial information used to create paper and electronic maps, allow for several additional analyses, including an evaluation of geomorphological changes occurring in the coastal zone. This research is particularly important in places where the shape of the coastal zone has been violently disturbed, including by human activity....
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Determination of bulk solid concentration changes during granular flow in a silo with ECT sensors
PublicationW artykule przedstawiono wyniki doświadczeń pomiaru zmian koncentracji materiału granulowanego podczas przepływu silosowego. Zmiany zostały pomierzone przy pomocy tomografu. Doświadczenia wykonano w silosie cylindrycznym dla 2 różnych szorstkości ścian i różnych zagęszczeń suchego piasku.
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Regional and sectoral assessment on climate-change in Pakistan: Social norms and indigenous perceptions on climate-change adaptation and mitigation in relation to global context
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Kinetics of pollutants removal in hybrid treatment wetlands – Case study comparison
PublicationRecent years have seen an increasing interest in hybrid constructed wetland (HCW) systems for domestic sewage treatment. This paper is focused on kinetics of removal of the main pollutants occurring in wastewater i.e. organics expressed as chemical oxygen demand, biochemical oxygen demand and total nitrogen. The purpose of the article is to compare different HCW configurations in terms of mass removal rates (MRR) and removal rate...
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Kinetics of aquation of [Co(ODA)(H2O)3] induced by Fe(III)
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Kinetics of Flavoenzyme-Catalyzed Reduction of Tirapazamine Derivatives: Implications for Their Prooxidant Cytotoxicity
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Novel investigation of pyrolysis mechanisms and kinetics for functional groups in biomass matrix
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Nanocomposite of cement/graphene oxide – Impact on hydration kinetics and Young’s modulus
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Luminescence kinetics in silica gel doped with Tb3+ ions and ZnS:Mn2+ nanocrystals
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Kinetics and Mechanism of Potassium Persulphate/L-Serine Initiated Polymerization of Methylmethacrylate
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Crystallization kinetics of poly(ethylene adipate) investigated by differential scanning calorimetry
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Cure kinetics of epoxy/MWCNTs nanocomposites: Isothermal calorimetric and rheological analyses
PublicationA combinatorial route has been applied in cure kinetics study of epoxy nanocomposites containing multi-walled carbon nanotubes (MWCNTs) based on differential scanning calorimetry and rheokinetic analyses under isothermal conditions. Pristine and amine-modified MWCNTs bearing primary and secondary amines were used at very low concentrations (0.1 and 0.3 wt.% based on epoxy weight). Model-free and model-fitting methods were applied...
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Cure kinetics of epoxy/MWCNTs nanocomposites: Nonisothermal calorimetric and rheokinetic techniques
PublicationNonisothermal calorimetric and isothermal rheokinetic analyses were used to study cure kinetics of epoxy/anhydride systems containing very low concentration of pristine and amine-functionalized multiwalled carbon nanotubes (MWCNTs). Isoconversional methods were applied in calorimetric modeling of cure kinetics. Eα vs. α dependency and autocatalytic nature of curing were identified for both types of nanocomposites by isoconversional...
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Thermal-Resistant Polyurethane/Nanoclay Powder Coatings: Degradation Kinetics Study
PublicationIn the present study, thermal degradation kinetics of polyurethane (PU) powder coatings reinforced with organo-modified montmorillonite (OMMT) was investigated. PU nanocomposites were prepared in different concentrations of 1, 3, and 5 wt.% of OMMT via the extrusion method. The microstructure of the nanocomposites was observed by scanning electron microscope (SEM) illustrating uniform dispersion of OMMT nano-clay platelets in the...
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Ab initio chemical kinetics of Isopropyl acetate oxidation with OH radicals
PublicationGlobal reactivity descriptors of isopropyl acetate (IPA) and thermo-kinetic aspects of its oxidation via OH radicals have been studied. Transition state theory (TST) was utilized to estimate the bimolecular rate constants. Ten oxidation pathways have been investigated, and all of them are exothermic. The potential energy diagram has been sketched using different pre- and post-reactive complexes for all reaction pathways. Rate coefficient...
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Aplication of theory of constraints thinking process in change management
PublicationW rozdziale przedstawiono schemat realizacji zmiany z wykorzystaniem metodologii zgodnego z Teorią Ograniczeń Logicznego Wnioskowania. Scharakteryzowano ponadto cel i zakres stosowania poszczególnych narzędzi Logicznego Wnioskowania w zarządzaniu zmianą. Zaprezentowano również zastosowanie Logicznego Wnioskowania w pokonywaniu kolejnych warstw oporu wobec zmian oraz omówiono rolę poszczególnych narzędzi w tym zakresie.
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Learning from Mistakes. A Study on Maturity and Adaptability to Change
PublicationLearning culture matters; company culture must support continuous improvement. Organizational learning is a process of identifying and modifying mistakes that result from interactions between co-workers. The article aims to explore the learning power via errors, using the level of organizational maturity as a moderator. Companies need to know how organizational maturity may moderate the adaptability to change via the acceptance...
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A review of phase change materials and heat enhancement methodologies
PublicationPhase change materials (PCMs) are an efficient alternative to store and release heat at a specific range of temperature. Here PCMs and heat enhancement methodologies for PCM storage are reviewed. A short overview of PCMs and their applications is presented in addition to the progress during the last 10 years. Heat enhancement techniques, that is, extended surfaces, multiple and composite PCMs, and encapsulation techniques, are...
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Overview of Fading Channel Modeling
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The Boltzmann sequence-structure channel
PublicationWe rigorously study a channel that maps binary sequences to self-avoiding walks in the two-dimensional grid, inspired by a model of protein statistics. This channel, which we also call the Boltzmann sequence-structure channel, is characterized by a Boltzmann/Gibbs distribution with a free parameter corresponding to temperature. In our previous work, we verified experimentally that the channel capacity has a phase transition for...
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Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
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The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability
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Life-long norepinephrine transporter (NET) knock-out leads to the increase in the NET mRNA in brain regions rich in norepinephrine terminals
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The influence of statin monotherapy and statin-ezetimibe combined therapy on FoxP3 and IL 10 mRNA expression in patients with coronary artery disease
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Spor o sušestvovanii mira : vremâ i sposób sušestvovaniâ / Roman Ingarden ; przeł. Janina Kubka, Maxim W. Lebiediew
PublicationPrzekład na język rosyjski paragrafu 27 ''Wstępne uwagi o czasie konkretnym'', paragraf 28 ''Sposób istnienia zdarzeń'' i paragrafu 29 ''Sposób istnienia procesu''. Pierwszego Tomu ''Sporu o istnienie świata'' Romana Ingardena, wydanie Warszawa 1987.
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Social entrepreneurship and its hybridity determining resource challenges and chances
PublicationIn this conceptual paper, the author aims to grasp what are the particular challenges and opportunities in social entrepreneurship, in terms of resource access and mobilization, considering the hybrid nature of social enterprise. To this end, the author points to the nature of hybridity and discusses what advantages and disadvantages are inherent in financial, human and physical resources access for social enterprises as hybrid...
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Specific Chemical and Genetic Markers Revealed a Thousands-Year Presence of Toxic Nodularia spumigena in the Baltic Sea
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Genetic Determinants of Antagonistic Interactions and the Response of New Endophytic Strain Serratia quinivorans KP32 to Fungal Phytopathogens
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Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent <i>CARD11</i> mutations
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Linezolid-Resistant Enterococcus spp. Isolates from Foods of Animal Origin—The Genetic Basis of Acquired Resistance
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Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli
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Genetic inactivation and chemical inhibition of PARP-1 lead to increased cytotoxicity to antitumor triazoloacridone C-1305
PublicationOkreśliliśmy aktywność cytotoksyczną związku C-1305 wobec komórek z obniżoną aktywnością PARP-1 w wyniku działania inhibitora tego enzymu związku NU1025. Dane wskazują, że w zależności od rodzaju inhibitora topoizomerazy II obniżenie aktywności PARP-1 przez związek NU1025 prowadzi do zwiększenia bądź obniżenia cytotoksyczności tych leków. Działanie NU1025 prowadzi również do re-aktywacji szlaku p53 w komórkach HeLa, czego jak dotąd...
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A Simple Model of Linkage Disequilibrium and Genetic Drift in Human Genomic SNPs: Importance of Demography and SNP Age
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Liver Cirrhosis in Chronic Hepatitis B Patients Is Associated with Genetic Variations in DNA Repair Pathway Genes
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Molecular characterization of drug-resistant Mycobacterium tuberculosis strains from Poland by use of multiple genetic markers
PublicationW pracy przedstawiono wyniki genotypowania wielolekoopornych szczepów Mycobacterium tuberculosis, izolowanych od pacjentów z Polski.
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Hierarchical Estimation of Human Upper Body Based on 2D Observation Utilizing Evolutionary Programming and 'Genetic Memory'
PublicationNew method of the human body pose estimation based on single camera 2D observation is presented. It employs 3D model of the human body, and genetic algorithm combined with annealed particle filter for searching the global optimum of model state, best matching the object's 2D observation. Additionally, motion cost metric is employed, considering current pose and history of the body movement, favouring the estimates with the lowest...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Quantitative Analysis of Biofilm Formed on Vascular Prostheses by Staphylococcus Epidermidis with Different ica and aap Genetic Status
PublicationOBJECTIVES: This study aims to examine biofilm formed on vascular prostheses by Staphylococcus epidermidis with different ica and aap genetic status, and to evaluate the effect of antibiotic-modified prostheses on bacterial colonization. METHODS: Biofilm formation was determined using fluorescence microscopy imaging. Quantitative analysis was conducted using the biofilm coverage ratio (BCR) calculations. RESULTS: Our investigations...
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SPATIAL-TEMPORAL DETECTION OF CHANGES ON THE SOUTHERN COAST OF THE BALTIC SEA BASED ON MULTITEMPORAL AERIAL PHOTOGRAPHS
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Temporal changes in the content of labile and stabile mercury forms in soil and their inflow to the southern Baltic Sea
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Changes in Hydrographic Conditions Associated with 2005–2007 Storm Surges in the Odra Mouth — a Numerical Study
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The impact of drying and steaming processes on surface color changes of tension ad normal beech wood
PublicationThe aim of the article is to present the influence of high temperature to selected properties of beech wood (Fagus sylvatica L.). The properties such as moisture content, color changes and longitudinal warping were analyzed. The quality of beech wood is determined based on structure and properties of wood, frequency of defects in wood material. The tension wood is considered as an important wood defect causing negative alterations...
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Structural changes of water caused by non-electrolytes: Volumetric and compressibility approach for urea-like analogues
PublicationHydration of thiourea (TU), hydroxyurea (HU, hydroxycarbamide), acetone (AC, 2-propanone) and dimethyl sulfoxide (DMSO) has been investigated with the help of the volumetric and compression measurement. The apparent molar volumes and the apparent molar isentropic (adiabatic) compression have been calculated from the density and speed of sound data at temperatures ranging from 288.15 to 308.15 K at atmospheric pressure (0.1 MPa)....
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DNA Methylation Changes Induced by Redox-Active Compounds—Choosing the Right PCR-Based Method
PublicationThe impact of catechins on the expression profile of redox-related genes in HT29 cell line has been studied recently by our group using Oxidative Stress RT2 Profiler PCR Array. Within the examined panel of 84 genes, the down-regulation of SRXN1 gene was unique among other up-regulated genes. We hypothesized that the observed down-regulation resulted from DNA methylation and have exploited this observation to choose the proper strategy...
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Reliability of Multi-rotor UAV’s Flight Stabilization Algorithm in Case of Object’s Working Point Changes
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Chemical and Enzymatic Changes of Different Soils during Their Acidification to Adapt Them to the Cultivation of Highbush Blueberry
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Phase Transitions and Structural Changes in DPPC Liposomes Induced by a 1-Carba-Alpha-Tocopherol Analogue
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Structural and Microhardness Changes After Turning of the AISI 1045 Steel for Minimum Quantity Cooling Lubrication
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