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Search results for: GRAF PLANARNY
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Unraveling the Interplay between DNA and Proteins: A Computational Exploration of Sequence and Structure-Specific Recognition Mechanisms
PublicationMy PhD dissertation focused on DNA-protein interactions and the recognition of specific DNA sequences and structures. I discovered that acidic amino acid residues (Asp/Glu) play a crucial role by exhibiting a preference for cytosine. Their contribution to binding affinity depends on nearby cytosines, balancing electrostatic repulsion with specific interactions. Acidic residues act as negative selectors, discouraging non-cytosine...
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Hat problem on odd cycles
PublicationThe topic is the hat problem in which each of n players is randomly fitted with a blue or red hat. Then everybody can try to guess simultaneously his own hat color by looking at the hat colors of the other players. The team wins if at least one player guesses his hat color correctly, and no one guesses his hat color wrong; otherwise the team loses. The aim is to maximize the probability of a win. In this version every player can...
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Radio Channel Measurements in Off-Body Communications in a Ferry Passenger Cabin
PublicationThis paper presents an off-body radio channel measurements in a ferry passenger cabin at 2.45 GHz band, for static sleeping scenarios with different body orientation and on-body antennas placements, and also for upper and lower sleeping berths. The measurements have been performed with two types of on-body wearable receiving antennas: FlexPIFA (flexible planar inverted F antenna), and FlexNotch (flexible adhesive-backed notch antenna)...
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Preclusion of irreversible destruction of Dr adhesin structures by a high activation barrier for the unfolding stage of the fimbrial DraE subunit
PublicationFimbrie Dr uropatogennych szczepów Escherichia coli stanowią przykład eksponowanych powierzchniowo struktur adhezyjnych podlegających biogenezie według zakonserwowanego, pośród bakterii Gram-ujemnych, systemu "chaperone-usher" ("białko opiekuńcze-zewnątrzbłonowe białko kanałowe"). Powyższe struktury adhezyjne są niezbędne w procesie specyficznej adhezji bakterii do receptorów zlokalizowanych na powierzchni docelowych komórek gospodarza....
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A two-plasmid Escherichia coli system for expression of Dr adhesins
PublicationPraca opisuje konstrukcję wydajnego systemu produkcji fimbrii Dr. System składa się z dwóch plazmidów. Plazmid pACYCpBAD-DraC-C-His zawiera pod kontrolą promotora arabinozowego gen draC kodujący białko kanałotwórcze DraC. Plazmid pET-30b-sygDraBE zawiera pod kontrolą promotora T7lac geny draB i draE kodujące odpowiednio białko opiekuńcze DraB oraz adhezynę DraE. Oba plzamidy posiadają różne ori replikacji co pozwala na ich jednoczesne...
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Use of a wastewater recovery product (struvite) to enhance subtropical seagrass restoration
PublicationSeagrasses are in decline worldwide, and their restoration is relatively expensive and unsuccessful compared to other coastal systems. Fertilization can improve seagrass growth in restoration but can also release nutrients and pollute the surrounding ecosystem. A slow-release fertilizer may reduce excessive nutrient discharge while still providing resources to the seagrass's rhizosphere. In this study, struvite (magnesium ammonium...
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Urinary Tract Infections of Escherichia coli Strains of Chaperone-Usher System
PublicationZakażenia dróg moczowych stanowią bardzo poważny problem zdrowotny i ekonomiczny dotyczący milionów ludzi, każdego roku na całym świecie. Najbardziej rozpowszechnionym czynnikiem etiologicznym tego typu infekcji bakteryjnych, obejmujących górne i dolne drogi moczowe, są szczepy E. coli, reprezentujące około 80% przypadków. Uropatogenne szczepy E. coli produkują kilka czynników urowirulentncyh, które można podzielić na dwa główne...
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Prime-Boost Vaccination with Toxoplasma Lysate Antigen, but Not with a Mixture of Recombinant Protein Antigens, Leads to Reduction of Brain Cyst Formation in BALB/c Mice
PublicationIntroduction Infection with the ubiquitous parasite Toxoplasma gondii is a threat for immunocompro- mised patients and pregnant women and effective immune-prophylaxis is still lacking. Methods Here we tested a mixture of recombinant T . gondii antigens expressed in different develop- mental stages, i.e., SAG1, MAG1 and GRA7 (SMG), and a lysate derived from T . gondii tachyzoites (TLA) for prophylactic vaccination against cyst formation....
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Computer-Aided Diagnosis of COVID-19 from Chest X-ray Images Using Hybrid-Features and Random Forest Classifier
PublicationIn recent years, a lot of attention has been paid to using radiology imaging to automatically find COVID-19. (1) Background: There are now a number of computer-aided diagnostic schemes that help radiologists and doctors perform diagnostic COVID-19 tests quickly, accurately, and consistently. (2) Methods: Using chest X-ray images, this study proposed a cutting-edge scheme for the automatic recognition of COVID-19 and pneumonia....
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Tuning of photocatalytic activity by creating a tridentate coordination sphere for palladium
PublicationThe synthesis and characterisation of an asymmetric potential bridging ligand bmptpphz (bmptpphz = 2,17-bis(4-methoxyphenyl)tetrapyrido[3,2-a:2’,3’-c:3’’,2’’-h:2’’’,3’’’-j] phenazine) is presented. This ligand contains a 1,10-phenanthroline (phen) and a 2,9-disubstituted phen sphere and possesses a strong absorbance in the visible. Facile coordination of the phen sphere to a Ru(tbbpy)2 core leads to Ru(bmptpphz) ([(tbbpy)2Ru(bmptpphz)](PF6)2;...
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Regulation of LPS assembly via controlled proteolysis and sensing of LPS stress in Escherichia coli
PublicationLipopolysaccharide (LPS) is a complex glycolipid, essential for the bacterial viability and along with phospholipids, it constitutes the major amphiphilic component of outer membrane (OM) in most of the Gram-negative bacteria, including Escherichia coli. LPS molecules confer an effective permeability barrier to the OM and play a crucial role in bacteria-environment and -host interactions. The synthesis and accumulation of this...
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The Antimicrobial Potential of Bacteria Isolated from Honey Samples Produced in the Apiaries Located in Pomeranian Voivodeship in Northern Poland
PublicationThe principal objective of this study was to determine whether the honeys produced in apiaries located in Pomeranian Voivodeship (Northern Poland) contain bacteria producing metabolites with growth inhibition potential against important human and animal pathogens. The pathogens included Staphylococcus aurues, Staphyloccocus epidermidis, Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, and Candida albicans. From...
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Expedited Re-Design of Multi-Band Passive Microwave Circuits Using Orthogonal Scaling Directions and Gradient-Based Tuning
PublicationGeometry scaling of microwave circuits is an essential but challenging task. In particular, the employment of a given passive structure in a different application area often requires re-adjustment of the operating frequencies/bands while maintaining top performance. Achieving this necessitates utilization of numerical optimization methods. Nonetheless, if the intended frequencies are distant from the ones at the starting point,...
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Crystal and electronic structures of Ni(II) silanethiolates containing flexible diamine ligands
PublicationFive nickel(II) complexes containing aliphatic diamines and tri-tert-butoxysilanethiolate ligand have been synthesized for the purpose of studying their structural, spectral (IR, UV–Vis, HF EPR) and thermal properties. Complexes (1)–(5) have been prepared in high yield by reactions of [Ni{SSi(OtBu)3}2(NH3)(H2O)] with 1.3-propanediamine (L1), 1,6-hexanediamine (L2), or 1,7-heptanediamine (L3). The X-ray structures were determined...
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Synthesis, structural characterization and reactivity of new trisubstituted N1-acylamidrazones: solid state and solution studies
PublicationA series of new linear trisubstituted N1-acylamidrazones have been investigated using a variety of analytical techniques and theoretical calculations to check the influence of the type of N1-acyl substituent on the resonance forms and conformational behavior in the solid state and in solution. The 1D- and 2D-NMR experiments, supported by computational studies, revealed that in solution all amidrazones exhibit conformational syn/anti...
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Structural and spectroscopic analysis of a new family of monomeric diphosphinoboranes
PublicationWe present a series of amino- and aryl(diphosphino)boranes R2PB(R’’)PR’2, where R2P, R’2P = tBu2P, tBuPhP, Ph2P, Cy2P, and R’’ = iPr2N, Ph, which were obtained via the metathesis reaction of iPr2NBBr2 or PhBBr2 with selected lithium phosphides. The structures of isolated diphosphinoboranes were characterized in the solid state and in solution by means of X-ray diffraction and NMR spectroscopy, respectively. The utility of these...
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Rapid multi-objective optimization of antennas using nested kriging surrogates and single-fidelity EM simulation models
PublicationEver increasing performance requirements make the design of contemporary antenna systems a complex and multi-stage process. One of the challenges, pertinent to the emerging application areas but also some of the recent trends (miniaturization, demands for multi-functionality, etc.), is the necessity of handling several performance figures such as impedance matching, gain, or axial ratio, often over multiple frequency bands. The...
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Homoleptic mono-, di-, and tetra-iron complexes featuring phosphido ligands: a synthetic, structural, and spectroscopic study
PublicationWe report the first series of homoleptic phosphido iron complexes synthesized by treating either the β-diketiminato complex [(Dippnacnac)FeCl2Li(dme)2] (Dippnacnac = HC[(CMe)N(C6H3-2,6-iPr2)]2) or [FeBr2(thf )2] with an excess of phosphides R2PLi (R = tBu, tBuPh, Cy, iPr). Reaction outcomes depend strongly on the bulkiness of the phosphido ligands. The use of tBu2PLi precursor led to an anionic diiron complex 1 encompassing a planar...
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Mechanism of recognition of parallel G-quadruplexes by DEAH/RHAU helicase DHX36 explored by molecular dynamics simulations
PublicationBecause of high stability and slow unfolding rates of G-quadruplexes (G4), cells have evolved specialized helicases that disrupt these non-canonical DNA and RNA structures in an ATP-dependent manner. One example is DHX36, a DEAH-box helicase, which participates in gene expression and replication by recognizing and unwinding parallel G4s. Here, we studied the molecular basis for the high affinity and specificity of DHX36 for parallel-type...
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On Fast Multi-objective Optimization of Antenna Structures Using Pareto Front Triangulation and Inverse Surrogates
PublicationDesign of contemporary antenna systems is a challenging endeavor, where conceptual developments and initial parametric studies, interleaved with topology evolution, are followed by a meticulous adjustment of the structure dimensions. The latter is necessary to boost the antenna performance as much as possible, and often requires handling several and often conflicting objectives, pertinent to both electrical and field properties...
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A nanoscaled contactless thermometer for biological systems
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Aging and Hypertension – Independent or Intertwined White Matter Impairing Factors? Insights From the Quantitative Diffusion Tensor Imaging
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Comparison of antimicrobial activity of selected, commercially available wound dressing materials
PublicationOBJECTIVE: The aim of our study was to examine the antimicrobial potential of eight selected, commercially available wound dressings containing different antimicrobial agents: silver, chlorhexidine acetate, povidone-iodine, and manuka honey. METHOD: The materials were tested against four reference strains of bacteria: Staphylococcus aureus (PCM 2051), Staphylococcus epidermidis (PCM 2118), Pseudomonas aeruginosa (ATCC 27853),...
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Exploiting multi-interface networks: Connectivity and Cheapest Paths
PublicationLet G = (V,E) be a graph which models a set of wireless devices (nodes V) that can communicate by means of multiple radio interfaces, according to proximity and common interfaces (edges E). The problem of switching on (activating) the minimum cost set of interfaces at the nodes in order to guarantee the coverage of G was recently studied. A connection is covered (activated) when the endpoints of the corresponding edge share at...
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Near-Field Wireless Sensing of Plastics and Papers Using Frugal Peel-Off Passive Tag
PublicationThis article presents a novel frugal approach of testing plastics and papers using a near-field microwave sensing technique with a peel-off tag. The proposed sensing technique involves two electrical entities: the sensor, which may be regarded as a reader, and a disposable tag. The reader is a modified design of a gap-coupled microstrip line (GCML) sensor, while the passive tag is a standard double-ring complementary split-ring...
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Generalized Formulation of Response Features for Reliable Optimization of Antenna Input Characteristics
PublicationElectromagnetic (EM)-driven parameter adjustment has become imperative in the design of modern antennas. It is necessary because the initial designs rendered through topology evolution, parameter sweeping, or theoretical models, are often of poor quality and need to be improved to satisfy stringent performance requirements. Given multiple objectives, constraints, and a typically large number of geometry parameters, the design closure...
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Chemical Composition and Antimicrobial Activity of New Honey Varietals
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Social health and dementia: a European consensus on the operationalization of the concept and directions for research and practice
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The noncanonical disulfide bond as the important stabilizing element of the immunoglobulin fold of the Dr fimbrial DraE subunit
PublicationAdhezyny fimbrialne bakterii patogennych stanowią liniowe asocjaty białkowe odpowiedzialne za wiązanie do specyficznych receptorów na powierzchni komórek gospodarza. Biogeneza tych struktur odbywa się przez system sekrecji typu chaperone/usher zakonserwowany pośród bakterii Gram-ujemnych. Powyższe struktury adhezyjne charakteryzują się wysoką odpornością na denaturację i deasocjację, powodowane przez temperaturę lub chemiczne czynniki...
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Formaldehyd w różnych formach opadów i osadów atmosferycznych na terenach o wysokim stopniu zurbanizowania
PublicationNajwiększy udział w dostawie zanieczyszczeń z atmosfery do powierzchni ziemi w regionach położonych w znacznych odległościach od źródeł emisji ma depozycja mokra. Opady atmosferyczne będące produktem kondensacji pary wodnej zawartej w atmosferze, na skutek adiabatycznego ochładzania się powietrza, opadają na powierzchnię ziemi (deszcz, śnieg, mżawka, krup, grad), unoszą się w powietrzu (mgła) albo osiadają (rosa, szron, szadź)....
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The value of less Light – Sustainable architectural lighting design
PublicationSince its beginning, the art of external illumination has substantially influ-enced the creation and the perception of architecture and the night-time urban environment. In her lecture, the author examines and defines the significant interdisciplinary conditions related to architectural lighting design that have evolved over the years, starting from the first simple exterior lighting projects to the more modern, complex concepts...
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Global defensive sets in graphs
PublicationIn the paper we study a new problem of finding a minimum global defensive set in a graph which is a generalization of the global alliance problem. For a given graph G and a subset S of a vertex set of G, we define for every subset X of S the predicate SEC ( X ) = true if and only if | N [ X ] ∩ S | ≥ | N [ X ] \ S | holds, where N [ X ] is a closed neighbourhood of X in graph G. A set S is a defensive alliance if and only if for...
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Dielectric Spectroscopy Studies and Modelling of Piezoelectric Properties of Multiferroic Ceramics
PublicationCompounds and solid solutions of bismuth ferrite (BiFeO3)—barium titanate (BaTiO3) system are of great scientific and engineering interest as multiferroic and potential high-temperature lead-free piezoelectric materials. In the present paper, the results of research on the synthesis and characterisation of 0.67Bi1.02FeO3–0.33BaTiO3 (67BFBT) ceramics in terms of crystal structure and dielectric and piezoelectric properties are reported....
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Solubility of Methane in Water: Some Useful Results for Hydrate Nucleation
PublicationIn this paper, the solubility of methane in water along the 400 bar isobar is determined by computer simulations using the TIP4P/Ice force field for water and a simple LJ model for methane. In particular, the solubility of methane in water when in contact with the gas phase and the solubility of methane in water when in contact with the hydrate has been determined. The solubility of methane in a gas–liquid system decreases as temperature...
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Dlaczego warto uczyć się matematyki?
Publication„Matematyka, jako wyraz myśli ludzkiej, odzwierciedla czynną wolę, kontemplacyjny rozum i dążenie do doskonałości estetycznej. Jej podstawowymi elementami są: logika i intuicja, analiza i konstrukcja, uogólnianie i indywidualizowanie. Różne tradycje podkreślały różne spośród tych aspektów, jednak tylko gra tych przeciwstawnych sił, walka o ich syntezę stanowi o żywotności, użyteczności i ogromnym znaczeniu matematyki” – cytat ten...
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Effects of La0.8Sr0.2MnO3 and Ag electrodes on bismuth-oxide-based low-temperature solid electrolyte oxygen generators
PublicationIn this study, La0.8Sr0.2MnO3 (LSM) was used as the ceramic electrode in a (Bi1.50Y0.50)0.98Zr0.04O3+δ (BYO)-based solid electrolyte oxygen generator (SEOG) and its performance was compared with that of a previously studied high-fire Ag electrode. Among La0.6Sr0.4Co0.2Fe0.8O3, LaNi0.6Fe0.4O3, Cu1.4Mn1.6O4, and LSM materials, only LSM materials did not trigger any chemical reaction or interdiffusion with BYO at temperatures up to...
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Fast multi-objective optimization of antenna structures by means of data-driven surrogates and dimensionality reduction
PublicationDesign of contemporary antenna structures needs to account for several and often conflicting objectives. These are pertinent to both electrical and field properties of the antenna but also its geometry (e.g., footprint minimization). For practical reasons, especially to facilitate efficient optimization, single-objective formulations are most often employed, through either a priori preference articulation, objective aggregation,...
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Aortic stiffness is not only associated with structural but also functional parameters of retinal microcirculation
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Bile salts in digestion and transport of lipids
PublicationBecause of their unusual chemical structure, bile salts (BS) play a fundamental role in intestinal lipid digestion and transport. BS have a planar arrangement of hydrophobic and hydrophilic moieties, which enables the BS molecules to form peculiar self-assembled structures in aqueous solutions. This molecular arrangement also has an influence on specific interactions of BS with lipid molecules and other compounds of ingested food...
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Thromboelastometric Analysis of Anticancer Cerrena unicolor Subfractions Reveal Their Potential as Fibrin Glue Drug Carrier Enhancers
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A Single-Center Experience of Renal Transplantation in Elderly Patients: A Paired-Kidney Analysis
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Biofilm formation as a virulence determinant of uropathogenic Escherichia coli Dr+ strains
PublicationInfekcje dróg moczowych stanowią największy problem zdrowotny dotykający miliony osób populacji ludzkiej każdego roku. Uropatogenne szczepy Escherichia coli są najczęstszym czynnikiem etiologicznym odpowiedzialnym za wywoływanie górnych i dolnych dróg moczowych. Powyższe szczepy bakteryjne produkują szereg czynników wirulentnych pośród, których wyróżnić można eksponowane powierzchniowo polimeryczne struktury adhezyjne (fimbrie/pile)...
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A five-year retrospective study shows increasing rates of antimicrobial drug resistance in Cabo Verde for both Staphylococcus aureus and Escherichia coli
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A five-year retrospective study shows increasing rates of antimicrobial drug resistance in Cabo Verde for both Staphylococcus aureus and Escherichia coli
PublicationObjectives Data on baseline drug resistance is important in informing future antimicrobial stewardship programs. So far, no data on the antimicrobial drug resistance of clinical isolates was available for the African archipelago of Cabo Verde. Methods We have performed a retrospective analysis over five-years (2013-17) of the antimicrombial drug susceptibility profiles of clinical isolates in the two main hospitals of Cabo Verde....
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Doskonalenie strumienia wartości
PublicationKsiążka ta ma na celu praktyczne ujęcie problemu optymalizacji przedsiębiorstwa opartej na koncepcji Lean (z ang. Lean – szczupły) i jej narzędziu Mapowania Strumienia Wartości. ---- Tu pobierzesz jej pełną treść w wersji elektronicznej: https://drive.google.com/file/d/1xNrdiuOHKpyjzG5dY3ocFG8fp2hY1b9C/view?usp=sharing ---- Prezentowane...
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Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations
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Gendered Self-Views Across 62 Countries: A Test of Competing Models
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10Kin1day: A Bottom-Up Neuroimaging Initiative
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10Kin1day: A bottom-up neuroimaging initiative
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Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment
PublicationWe present the results for CAPRI Round 50, the 4th joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of 12 targets, including 6 dimers, 3 trimers, and 3 higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly...