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Search results for: IN VITRO METABOLIZM
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Interfacial behaviour of human bile and its substitution for in vitro lipolysis studies
PublicationThis study examined the interfacial evolution of individual bile salts (BSs) and their blends with phosphatidylcholine (BS/PC) to simulate the complex behaviour of human bile (HB) during lipolysis at the triglyceride/water interface. Using adsorption and desorption cycles, mimicking exposure to small intestinal fluids, we demonstrate that the interfacial behaviour of real HB can be replicated using simple mixtures of BSs and PC....
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Biological and mechanical properties of bone cement with nanoarticles - in vitro and in vivo research
PublicationDespite antibiotic preventive treatment both before and after implant implementation, the risks of infection are real. These infections develop at the implant surface a few months after inserting them into the body. To prevent the development of bacteria and reduce the risk of infection, implants coated with nanoparticles are used. The Mechanical Department of the Technical University of Gdansk carries out research into using bone...
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In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium
PublicationDespite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium–phosphate...
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The differentiation and transdifferentiation of epithelial cells in vitro – is it a new strategy in regenerative biomedicine?
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In Vitro Toxicological Screening of Stable and Senescing Cultures of Aphanizomenon, Planktothrix, and Raphidiopsis
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Protective effect of desloratadine against oxidative stress in human erythrocytes in vitro
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Formulation, characterisation and in vitro studies of doxorubicin-loaded silica–polydimethylsiloxane granules
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Synthesis and in vitro characterization of freeze-dried doxorubicin-loaded silica xerogels
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Size-Dependent in Vitro Biocompatibility and Uptake Process of Polymeric Carbon Nitride
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Agomelatine's antiglycoxidative action—In vitro and in silico research and systematic literature review
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Biodegradable macromolecular conjugates of citropin: Synthesis, characterization and in vitro efficiency study
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Metody oznaczania in vitro właściwości przeciwutleniających próbek żywności. Cz. I
PublicationWystępowanie większości chorób cywilizacyjnych może być rezultatem stresu oksydacyjnego prowadzącego do różnorodnych zmian w ludzkim organizmie, wywołanych działaniem tzw. reaktywnych form tlenu. Z tego też powodu pojawiło się olbrzymie zapotrzebowanie na szybkie testy umożliwiające pomiar całkowitej zawartości przeciwutleniaczy czy też ogólnej siły przeciwutleniającej produktów żywnościowych a w szczególności świeżych warzyw...
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Effects of local anesthetics on the respiratory burst of cord blood neutrophils in vitro
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COMPARISON OF PROPAGATION METHOD IN IN VITRO AND IN VIVO CONDITION OF Lonicera caerulea L.
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PROTOCOL FOR IN VITRO MASS PRODUCTION OF NEPHROLEPIS EXALTATA SCHOTT (BOSTON FERN)
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In vitro Culture and Bulblets Induction of Asiatic Hybrid Lily ‘Red Alert’
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In vitro and in vivo biological activities of azulene derivatives with potential applications in medicine
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Metaboliczny potencjał energetyczny miast
PublicationTekst przedstawia koncepcje przepływów energii w strukturach zurbanizowanych. Zaprezentowano kolejno: metabolizm jako próbę oznaczenia zmiany, cechy anaboliczne i kataboliczne w dynamice miasta, nowe zwiastuny metabolizmu, rozlewanie i kurczenie się miast oraz "chirurgów" metabolizmu polskich miast.
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Skin microbiota metabolism of natural products from comfrey root (Symphytum officinale L.)
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Interspecific allelopathy in cyanobacteria: Cylindrospermopsin and Cylindrospermopsis raciborskii effect on the growth and metabolism of Microcystis aeruginosa
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Glucose metabolism disorders in patients with non-functioning adrenal adenomas — single-centre experience
PublicationIntroduction: The presence of glucose metabolism disorders and their possible correlation with degree of cortisol secretion were evaluated in patients with non-functioning adrenal incidentalomas (NFAIs). Material and methods: The study group consisted of 131 patients with hormonally inactive adrenal incidentalomas....
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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The role of cytochrome P450 reductase (CPR) in metabolism of potent nitroacridine antitumor, C-1748
PublicationCelem pracy było poznanie molekularnego mechanizmu działania pochodnych 9-amino-1-nitroakrydyny. Zbadano przemiany enzymatyczne tych związków w różnych układach enzymatycznych: I. Szczurza frakcja mikrosomalna z reduktazą cytochromu P450. II. Rekombinantowe izoenzymy cytochromu P450 z wysokim i niskim poziomem reduktazy cytochromu P450. III. Frakcje mikrosomalne dzikiego typu oraz pozbawione genu kodującego reduktazę cytochromu...
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Impact of Paleo Diet on Body Composition, Carbohydrate and Fat Metabolism of Professional Handball Players
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Platelets in fetal growth restriction: role of reactive oxygen species, oxygen metabolism, and aggregation.
PublicationFetal growth restriction (FGR) is mainly caused by failure of the uteroplacental unit. Theexact pathogenesis remains unclear. The cause is thought to be related to abnormal platelet activation,which may...
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Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion
PublicationPURPOSE: In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing provokes questions concerning potential epigenetic alterations occurring in expanded cells in the context of usefulness for transplantation and safety. The purpose of this study was to investigate as to whether keratinocyte expansion is associated with changes in the activity...
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Specificity of Infant Digestive Conditions: Some Clues for Developing Relevant In Vitro Models
PublicationDigestion of nutrients is an essential function of the newborn infant gut to allow growth and development and understanding infant digestive function is essential to optimize nutrition and oral drug delivery. Ethical considerations prohibit invasive in vivo trials and as a consequence in vitro assays are often conducted. However, the choice of in vitro model parameters are not supported by an exhaustive analysis of the literature...
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PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke
PublicationIschemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...
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In vivo and in vitro study of a novel nanohydroxyapatite sonocoated scaffolds for enhanced bone regeneration
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The effect of electromagnetic field on reactive oxygen species production in human neutrophilsin vitro
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Anticancer properties of low molecular weight oat beta-glucan – An in vitro study
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Edible Flowers Extracts as a Source of Bioactive Compounds with Antioxidant Properties—In Vitro Studies
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Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids
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Preparation and in vitro characterisation of bioactive mesoporous silica microparticles for drug delivery applications
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Synthesis and in vitro characterization of freeze-dried doxorubicin-loaded silica/PEG composite
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Polyphenol-Enriched Composite Bone Regeneration Materials: A Systematic Review of In Vitro Studies
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In vitro enzyme inhibitory properties, antioxidant activities, and phytochemical profile of Potentilla thuringiaca
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In vitro anticariogenic effects of aerial parts of Drymocallis rupestris and its phytochemical profile
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In vitro anticariogenic effects of aerial parts of Potentilla recta and its phytochemical profile
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Cinnamon powder: an in vitro and in vivo evaluation of antifungal and plant growth promoting activity
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Butyrylcholinesterase signal sequence self-aggregates and enhances amyloid fibril formation in vitro
PublicationAlzheimer’s disease (AD) pathogenesis has been attributed to extracellular aggregates of amyloid β (Aβ) plaques and neurofibrillary tangles in the human brain. It has been reported that butyrylcholinesterase (BChE) also accumulates in the brain Aβ plaques in AD. We have previously found that the BChE substitution in 5′UTR caused an in-frame N-terminal extension of 41 amino acids of the BChE signal peptide. The resultant variant...
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Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome
PublicationBisphenols (BPs) have become a chemical group of special interest due to their ability to interfere with the endocrine system and their ubiquitous presence in the environment. As some of them possess mild estrogenic and anti-androgenic effects, they might be associated with the diagnosis of polycystic ovary syndrome (PCOS). Acting on multiple tissues, BPs exposure may lead to metabolic derangements characteristic for metabolic...
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IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection
PublicationCellular lipid metabolism plays a pivotal role in human cytomegalovirus (HCMV) infection, as increased lipogenesis in HCMV-infected cells favors the envelopment of newly synthesized viral particles. As all cells are equipped with restriction factors (RFs) able to exert a protective effect against invading pathogens, we asked whether a similar defense mechanism would also be in place to preserve the metabolic compartment from HCMV...
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Flavonoid biosynthetic pathways in plants: Versatile targets for metabolic engineering
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Carbon assimilation profiles of mucoralean fungi show their metabolic versatility
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The metabolic syndrome in hypertension: European society of hypertension position statement
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Electronic Cigarette Use and Metabolic Syndrome Development: A Critical Review
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The usefulness of fluorescence in detecting ischemia during bariatric and metabolic surgery
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A numerical scale to assess the outcomes of metabolic/bariatric surgery (NOMS)
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