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Search results for: INVERSE AGONIST
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Failure analysis of a high-speed induction machine driven by a SiC-inverter and operating on a common shaft with a high-speed generator
PublicationDue to ongoing research work, a prototype test rig for testing high-speed motors/generators has been developed. Its design is quite unique as the two high- speed machines share a single shaft with no support bearings between them. A very high maximum operating speed, up to 80,000 rpm, was required. Because of the need to minimise vibration during operation at very high rotational speeds, rolling bearings were used. To eliminate...
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Using AOP-Wiki to support the ecotoxicological risk assessment of nanomaterials: first steps in the development of novel adverse outcome pathways
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Space Vector Pulsewidth Modulation Strategy for Multilevel Cascaded H-Bridge Inverter With DC-Link Voltage Balancing Ability
PublicationSpace vector pulsewidth modulation (SVPWM) algorithms for cascaded H-bridge multilevel (CHB ML) inverter usually provide the possibility of using several combinations of active voltage vectors to generate the same output voltage vector. For preselected H-bridges, some of them may generate output voltages opposite to the assumed direction. This results in the change of the dc-link voltages of these H-bridges in the opposite direction...
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Inline Microstrip Bandpass Filter With Two Transmission Zeros and Increased Order Using Spurious Resonance of Frequency-Dependent Inverter
PublicationA design method for a class of fourth-order inline microstrip bandpass filter with two transmission zeros and 20% fractional bandwidth is presented. The filter consists of two quarter-wavelength transmission-line resonators coupled by a frequency-dependent inverter. The inverter is composed of two open-ended stubs that are connected by an interdigital capacitor and introduces two poles and two transmission zeros in the filter response....
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Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
PublicationThe genome feature of SARS-CoV-2 leads the virus to mutate and creates new variants of concern. Tackling viral mutations is also an important challenge for the development of a new vaccine. Accordingly, in the present study, we undertook to identify B- and T-cell epitopes with immunogenic potential for eliciting responses to SARS-CoV-2, using computational approaches and its tailoring to coronavirus variants. A total of 47 novel...
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Inhibiting Activity of HIV-1: Protease, Reverse Transcriptase and Integrase All Together by Novel Compounds Using Computational Approaches
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FPGA implementation of reverse residue conversion based on the new Chinese Remainder Theorem II- Part II,- Experimantal results
PublicationW pracy opisano realizację sprzętową konwertera z systemu resztowego do systemu binarnego. Konwerter jest oparty na nowej formie chińskiego twierdzenia o resztach CRT II. Teoretyczne aspekty takiej konwersji przedstawiono w części I. Implementację konwertera wykonano w środowisku Xilinx FPGA. Zaprezentowano ogólną architekturę konwertera, a także opisano realizację wybranych bloków. Podano ilość koniecznych zasobów sprzętowych...
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Feasibility Study GaN Transistors Application in the Novel Split-Coils Inductive Power Transfer System with T-Type Inverter
PublicationA promising solution for inductive power transfer and wireless charging is presented on the basis of a single-phase three-level T-type Neutral Point Clamped GaN-based inverter with two coupled transmitting coils. The article focuses on the feasibility study of GaN transistor application in the wireless power transfer system based on the T-type inverter on the primary side. An analysis of power losses in the main components of the...
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An investigation of structural responses of inverted pavements by numerical approaches considering nonlinear stress-dependent properties of unbound aggregate layer
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Opposing Age-Related Trends in Absolute and Relative Risk of Adverse Health Outcomes Associated With Out-of-Office Blood Pressure
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Comparison of the Antioxidant Properties of Green Macroalgae from Diverse European Water Habitats by Use of Several Semi-Quantitative Assays
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Artificial Intelligence-Based Weighting Factor Autotuning for Model Predictive Control of Grid-Tied Packed U-Cell Inverter
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Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
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Determination of Nine Intense Sweeteners in Foodstuffs by High-Performance Liquid Chromatography and Evaporative Light-Scattering Detection: Interlaboratory Study
PublicationW pracy przedstawiono wyniki badań międzylaboratoryjnych, opracowanej wcześniej metody jednoczesnego oznaczania dziewięciu słodzików o wysokiej mocy w produktach żywnościowych. W badaniach wzięło udział siedem laboratoriów (Belgia, Niemcy, Portugalia). W rezultacie dowiedziono, iż opracowana metoda umożliwia uzyskanie dokładnych, powtarzalnych i odtwarzalnych wyników analiz dla wszystkich badanych słodzików i typów żywności.
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PCR-Based Genotyping of Mycobacterium tuberculosis with New GC-Rich Repeated Sequences and IS6110 Inverted Repeats Used as Primers.
PublicationW pracy przedstawiono nową metodę genotypowania Mycobacterium tuberculosis. Zastosowanie oligonukleotydu Mtb1 5'-CCG-GCG-GGG-CCG-GCG-G lub Mtb2 5'-CGG-CGG-CAA-CGG-CGG-C wraz z oligonukleotydami specyficznymi do terminalnych sekwencji elementu insercyjnego IS6110 pozwala na różnicowanie szczepów Mycobacterium tuberculosis w metodzie PCR. Opracowana metoda może być wykorzystana w badaniach epidemiologicznych gruźlicy.
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Electroporation with Cisplatin against Metastatic Pancreatic Cancer:In VitroStudy on Human Primary Cell Culture
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Evaluation of effectiveness of hydrated lime additive in protecting asphalt concrete against water and frost
PublicationArtykuł przedstawia wyniki badań laboratoryjnych odporności betonu asfaltowego z dodatkiem wapna hydratyzowanego na działanie wody i mrozu. Niszczące oddziaływanie wody i mrozu oceniano przez zestawienie wytrzymałości na pośrednie rozciąganie i modułu sztywnosci sprężystej przed i po laboratoryjnej symulacji działania wody i mrozu zmodyfikowaną metodą Lottmana. Działanie 2 środków adhezyjnych (wapna hydratyzowanego i aminu tłuszczowego)...
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Comparative Assessment of Bacteriophage and Antibiotic Activity against Multidrug-Resistant Staphylococcus aureus Biofilms
PublicationProblems connected with biofilm-related infections and antibiotic resistance necessitate the investigation and development of novel treatment strategies. Given their unique characteristics, one of the most promising alternatives to conventional antibiotics are bacteriophages. In the in vitro and in vivo larva model study, we demonstrate that phages vB_SauM-A, vB_SauM-C, and vB_SauM-D are effective antibiofilm agents. The exposure...
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Microwave-assisted synthesis of a TiO2-CuO heterojunction with enhanced photocatalytic activity against tetracycline
PublicationA microwave method was used for the synthesis of TiO2-CuO oxide systems. A detailed investigation was made of the effect of the molar ratio of components (TiO2:CuO=9:1, 7:3, 5:5, 3:7, 1:9) on the crystalline structure and morphology. Transmission electron microscopy (TEM) confirmed the presence of octahedral and rod-shaped titania particles and sheet copper(II) oxide particles; moreover, HRTEM analysis indicated the presence of...
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The Impact of the Antigenic Composition of Chimeric Proteins on Their Immunoprotective Activity against Chronic Toxoplasmosis in Mice
PublicationToxoplasmosis may pose a serious threat for individuals with weakened or undeveloped immune systems. However, to date, there is no specific immunoprophylaxis for humans. Thus, the aim of this study was to evaluate the immunogenicity of three trivalent—SAG2-GRA1-ROP1L (SGR), SAG1L-MIC1-MAG1 (SMM), and GRA1-GRA2-GRA6 (GGG)—and two tetravalent—SAG2-GRA1-ROP1-GRA2 (SGRG) and SAG1-MIC1-MAG1-GRA2 (SMMG)—chimeric T. gondii proteins, as...
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Distributed protection against non-cooperative node behavior in multi-hop wireless networks
PublicationAn important security problem in today's distributed data networks is the prevention of non-cooperative behavior i.e., attacks consisting in the modification of standard node operation to gain unfair advantage over other system nodes. Such a behavior is currently feasible in many types of computer networks whose communication protocols are designed to maximize the network performance assuming full node cooperation. Moreover, it...
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Decision Support System to Improve the Effectiveness of Chemical Control Against Cutworms in Sugar Beet
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Characterization of the Three New Kayviruses and Their Lytic Activity Against Multidrug-Resistant Staphylococcus aureus
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Incorporation of engineered nanoparticles of biochar and fly ash against bacterial leaf spot of pepper
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Social support against depression in young adults’ group during COVID-19 pandemic.
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Vaccination Against Measles, Mumps, and Rubella in the Light of Current Epidemic Threats: Unjustified Postponement
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Antimicrobial Activity of Selected Antimicrobial Peptides Against Planktonic Culture and Biofilm of Acinetobacter baumannii
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Application of Rotating Magnetic Fields Increase the Activity of Antimicrobials Against Wound Biofilm Pathogens
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Potential of Biocellulose Carrier Impregnated with Essential Oils to Fight Against Biofilms Formed on Hydroxyapatite
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Innate Immune Response against Staphylococcus aureus Preincubated with Subinhibitory Concentration of trans-Anethole
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Photochemical properties and photocytotoxicities against wound bacteria of sulfanyl porphyrazines with bulky peripheral substituents
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In vitro photodynamic activity of lipid vesicles with zinc phthalocyanine derivative against Enterococcus faecalis
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Protection Against Electric Shock Using Residual Current Devices in Circuits with Electronic Equipment
PublicationW artykule przedstawiono problematykę stosowania wyłączników różnicowoprądowych w obwodach z urządzeniami elektronicznymi, które powodują, że prąd różnicowy ma zmienną częstotliwość lub jest odkształcony. Wyniki badań wskazują, że częstotliwość obiegająca od znamionowej oraz zawartość wyższych harmonicznych w prądzie różnicowym niekorzystnie wpływa na skuteczność ochrony przeciwporażeniowej przy zastosowaniu wyłączników różnicowoprądowych....
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Overflowing tests at the Polish DredgDikes research dike – stability of the dike surface against erosion
PublicationIn the project DredgDikes the different research dike embankments were tested with respect to overflowing water induced erosion. Therefore, flumes were installed on the land side embankments in which the effect of overflowing water on the vegetated surface was investigated. On the Polish DredgDikes research dike near Gdansk, Poland, two parallel flumes were installed and the surface of the dike made of different mixtures of...
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Early warning models against bankruptcy risk for Central European and Latin American enterprises
PublicationThis article is devoted to the issue of forecasting the bankruptcy risk of enterprises in Latin America and Central Europe. The author has used statistical and soft computing methods to program the prediction models. It compares the effectiveness of twelve different early warningmodels for forecasting the bankruptcy risk of companies. In the research conducted, the author used data on 185 companies listed on the Warsaw Stock Exchange...
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Immunizing the Hillcast Method against the Known-Plaintext Attack using Periodic Key Exchange
PublicationThis paper considers a Joint Fingerprinting and Decryption method, called Hillcast, for the copyright protection and traitor tracing in case of Video on Demand services. Because the method is based on the Hill cipher, it is vulnerable to a known-plaintext attack. The goal of this paper is to present an efficient periodic key exchange mechanism to make this method secure without compromising its scalability, imperceptibility or...
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The consequences of applying a new Polish Water Law Act for protection against urban flooding
PublicationPrevious legal regulations did not create conditions for a comprehensive solution to the problems of the urban melioration complex. For over 20 years, urban flooding caused by atmospheric precipitation has been systematically recurring in Poland. The article was elaborated on the experience resulting from the 2001 and 2016 floods in Gdansk (Poland). The newly adopted Water Law Act creates a foundation for a systemic solution...
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A tribological research on a reciprocating sliding contact of aluminum-ferrous composite against cast-iron.
PublicationOpisano badania kompozytów: silumin AlSi11-żelazo albo silumin AlSi11-stal narzędziowa N9 (otrzymanych in situ), a także samego siluminu AlSi11 w skojarzeniu z żeliwem 350, przy tarciu ślizgowym w ruchu posuwisto-zwrotnym. Stwierdzono wpływ sposobu otrzymywania materiału kompozytowego na zużycie i opory ruchu skojarzenia badawczego, w szczególności materiały te zużywały się wolniej, niż silumin AlSi11.
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Conformation-activity relationships of cyclo-constrained μ/5 opioid agonists derived from the N-terminal tetrapeptide segment of dermorphin/deltorphin
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Evaluation of reverse osmosis for improving quality of water utilized in hemodialysis devices (case study: Kerman University of Medical Sciences' hospitals)
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Evaluation of reverse osmosis for improving quality of water utilized in hemodialysis devices (case study: Kerman University of Medical Sciences' hospitals).
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Separation of Monovinyl and Divinyl Protochlorophyllides Using C30 Reverse Phase High Performance Liquid Chromatography Column: Analytical and Preparative Applications
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Diverse behavioral, monoaminergic and Fos protein responses to opioids in Warsaw high-alcohol preferring and Warsaw low-alcohol preferring rats
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Testing the positioning accuracy of GNSS solutions during the tramway track mobile satellite measurements in diverse urban signal reception conditions
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Testing the Positioning Accuracy of GNSS Solutions during the Tramway Track Mobile Satellite Measurements in Diverse Urban Signal Reception Conditions
PublicationMobile Global Navigation Satellite System (GNSS) measurements carried out on the railway consist of using satellite navigation systems to determine the track geometry of a moving railway vehicle on a given route. Their purposes include diagnostics, stocktaking, and design work in railways. The greatest advantage of this method is the ability to perform measurements in a unified and coherent spatial reference system, which...
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Protective Effect of Black Tea Against Ethanol-Induced Oxidative Modifications of Liver Proteins and Lipids
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Response to Claudio Schuftan on “Three decades of fighting against hunger in Africa: Progress, challenges and opportunities”
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Phytochemical Profiling and Larval Control of Erythrina variegata Methanol Fraction against Malarial and Filarial Vector
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THE PROTECTIVE MEASURES AGAINST SARS-COV-2 INFECTION IN THE SEAFOOD COMPANY FROM THE PERSPECTIVE OF THE EMPLOYEES
PublicationPurpose: To identify and discuss the protective measures implemented to prevent SARS-CoV-2 infection among employees. Design/methodology/approach: The four-stage course of research. Case study and structured interviews with all employees, directly and indirectly, involved in food processing. Research questions: (R1) What measures have been taken to prevent the risk of infection among employees? (R2) What activities and responsibilities...
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Evaluation of antimicrobial activities of powdered cuttlebone against Klebsiella oxytoca, Staphylococcus aureus, and Aspergillus flavus
PublicationBackground: The presence of medicines in the environment is considered as a serious threat to the human health. The entrance of these substances into the water sources causes soil pollution, which eventually leads to the environmental pollution and it creates some problems for the public health. Also, increasing antibiotic resistant bacteria has attracted the attention of researchers to the use of natural resources such as marine...