Filters
total: 1868
-
Catalog
- Publications 775 available results
- Journals 17 available results
- Conferences 1 available results
- People 117 available results
- Inventions 5 available results
- Projects 7 available results
- Laboratories 2 available results
- Research Teams 1 available results
- Research Equipment 1 available results
- e-Learning Courses 222 available results
- Events 100 available results
- Open Research Data 620 available results
displaying 1000 best results Help
Search results for: atp synthase
-
ATA Journal of Legal Tax Research
Journals -
Wave energy attenuation in fields of colliding ice floes – Part 1: Discrete-element modelling of dissipation due to ice–water drag
Publication -
Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system
Publication -
Long range molecular dynamics study of interactions of the eukaryotic glucosamine-6-phosphate synthase with fructose-6-phosphate and UDP-GlcNAc
PublicationGlucosamine-6-phosphate synthase (EC 2.6.1.16) is responsible for catalysis of the first and practically irreversible step in hexosamine metabolism. The final product of this pathway, uridine 5 diphospho Nacetyl- d-glucosamine (UDP-GlcNAc), is an essential substrate for assembly of bacterial and fungal cell walls. Moreover, the enzyme is involved in phenomenon of hexosamine induced insulin resistance in type II diabetes, which...
-
Beneficial effect of ovocystatin on the cognitive decline in APP/PS1 transgenic mice
Publication -
PORÓWNANIE PROJEKTÓW BUDOWY FARM WIATROWYCH Z WYKORZYSTANIEM METODY AHP
PublicationW referacie opisano porównanie projektów budowy farm wiatrowych będących w różnych stadiach realizacji przygotowania inwestycji. Metodą, którą wykorzystano do porównania projektów jest metodą analizy wielokryterialnej AHP (Analytic Hierarchy Process). Referat przedstawia opis metody oraz kryteriów, pod względem których porównano projekty. Wykazano, że dla projektu P2 czas zdobycia wszystkich niezbędnych...
-
PROBLEM RUCHU SMS A2P - JEGO ANALIZA I SPOSOBY ROZWIĄZANIA
PublicationRuch SMSowy typu A2P (Application to Person) jest dla operatorów źródłem problemów, które objawiają się dla jednych w postaci strat, a dla innych nieuprawnionymi zyskami. W artykule omówiono ten problem od strony technicznej, tzn. gdzie leży jego przyczyna i jak można przeciwdziałać temu zjawisku i mieć jednocześnie z tego tytułu korzyści.
-
The Impact of the Quality of Tap Water and the Properties of Installation Materials on the Formation of Biofilms
Publication -
Self-healing ATM networks based on preplanned restoration of virtual paths
PublicationW pracy omówiono klasyfikację metod odtwarzania usług w samonaprawialnych sieciach ATM opartych na ścieżkach wirtualnych i o topologii kratkowej. Przedstawiono model z zaplanowanymi z góry ścieżkami zabezpieczającymi i wyniki badań przykładowej sieci w Polsce.
-
Zastosowanie metody AHP do oceny zagrożeń na stanowiskach pracy.
PublicationW artykule przedstawiono podstawy wielokryterialnej metody wspomagania decyzji AHP (ang. Analytic Hierarchy Process) oraz jej zastosowanie do oceny zagrożeń na stanowiskach pracy.
-
Modification of quaternary structure of Candida albicans GlcN-6-P synthase and its desensitization to inhibition by UDP-GlcNAc by site-directed mutagenesis
PublicationSite-directed mutagenesis of the CaGFA1 gene encoding glucosamine-6-phosphate synthase from Candida albicans was performed. Desensitization of the enzyme to inhibition by UDPGlcNAc was achieved upon T487I and H492F substitutions at the UDP-GlcNAc binding site, exchange of D524, S525 and S527 for Ala at the dimer:dimer interface and construction of the tail-lock array (L434R and L460A) at the C-tail region. The first two sets if...
-
Synthesis, anticandidal activity of N3-(4-methoxyfumaroyl)-(S)-2,3-diaminopropanoic amide derivatives – Novel inhibitors of glucosamine-6-phosphate synthase
PublicationNovel FMDP amiders 4-6 have been synthesized and tested against Candida strains. The anticandidal activity has been confined only to Candida albicans. Anticandidal activity of the tested amides has correlated with their inhibitory activity of glucosamine-6-phosphate synthase in cell free extract from Candida albicans.
-
Development of biocompatible iron oxide-silicon oxide core-shell nanoparticles as subcellular delivery platform for glucosamine-6-phosphate synthase inhibitors
PublicationIn order to develop the preparation of iron oxide-silica coreshell nanoparticles (CSNPs), thesis deeply explores the cetyltrimethylammonium (CTA+) directed silica coating methods of the oleic-acid capped iron oxide nanoparticles (OA-IONPs) initialized under near-neutral pH conditions. It is demonstrated that the initial alkaline hydrolysis of ethyl acetate in the presence of CTA+ and OA-IONPs induces an unusual ligand exchange...
-
Comparison of AHP and Numerical Taxonomy Methods Based on Biogas Plant Location Analysis
PublicationThe paper presents a comparison of the multi-criteria Analytic Hierarchy Process (AHP) method and numerical taxonomy in biogas plant location selection. Biogas plants are sources that will significantly contribute to the implementation of the provisions of the energy and climate package for Poland by 2030. Increasing the share of energy produced from renewable sources, e.g. biogas plants, will increase the country’s energy security....
-
Growth of polymer brushes by “grafting from” via ATRP – Monte Carlo simulations
Publication -
Evaluating the performance of inverted pavement structure using the accelerated pavement test (APT)
Publication -
COMPARISION OF TWO WIND FARMS CONSTRUCTION PROJECTS USING F-AHP METHODP
PublicationReferat przedstawia porównanie projektów dwóch farm wiatrowych. Częścią referatu jest opis kryteriów, które muszą zostać uwzględnione w trakcie analizy porównawczej projektów budowy FW. Tego typu analiza znajduje zastosowanie w przypadku zakupu projektów inwestycyjnych będących w fazie przygotowania. Spowodowane jest to koniecznością uwzględnienia wymogów określonych w ustawodawstwie polskim...
-
Mechanism of Biofilm Formation on Installation Materials and Its Impact on the Quality of Tap Water
Publication -
SELF-ENUCLEATION OF BOTH EYES IN SCHIZOPHRENIA & INTELLECTUAL DISABILITY: A CURSE OR A BLESSING?
Publication -
SELF-ENUCLEATION OF BOTH EYES IN SCHIZOPHRENIA & INTELLECTUAL DISABILITY: A CURSE OR A BLESSING?
Publication -
Using the AHP Method to Select an Electronic Documentation Management System for Polish Municipalities
Publication -
Cross-layer mDNS/ARP integration for IEEE 802.11s Wireless mesh Network
PublicationPopularization of mobile computing devices created a need for robust, efficient and ubiquitous methods of communication and network access. At the same time, evolution and standardization of Wireless Local Area Network (WLAN) technologies made them an attractive solution for building of complex network systems. Moreover, growing maturity of WLAN standards such as IEEE 802.11 allows for introduction of WLAN architectures other than...
-
Analiza lokalizacji biogazowni metodami AHP i taksonomi numerycznej - porównanie metod
PublicationArtykuł przedstawia porównanie wielokryterialnej metody Analytic Hierarchy Proces oraz taksonomii numerycznej w oparciu o wybór lokalizacji biogazowni.
-
Sylwester Kaczmarek dr hab. inż.
PeopleSylwester Kaczmarek received his M.Sc in electronics engineering, Ph.D. and D.Sc. in switching and teletraffic science from the Gdansk University of Technology, Gdansk, Poland, in 1972, 1981 and 1994, respectively. His research interests include: IP QoS and GMPLS and SDN networks, switching, QoS routing, teletraffic, multimedia services and quality of services. Currently, his research is focused on developing and applicability...
-
AITP - AI Thermal Pedestrians Dataset
Open Research DataAITP is a pedestrian detection dataset consisting of 9178 annotated thermal images. The training set contains 7801 images on which15448 pedestrians were labeled. The test set has 1377 images on which 2731 objects were marked. All images are in PNG file format (120x160) captured with FLIR Lepton Thermal Camera on the streets of Gdańsk, Poland. All pedestrians...
-
AP Arqueologia Publica
Journals -
Two small RNAs conserved in Enterobacteriaceae provide intrinsic resistance to antibiotics targeting the cell wall biosynthesis enzyme glucosamine-6-phosphate synthase
PublicationFormation of glucosamine-6-phosphate GlcN6P) by enzyme GlcN6P synthase (GlmS) represents the first step in bacterial cell envelope synthesis. In Escherichia coli, expression of glmS is controlled by small RNAs (sRNAs) GlmY and GlmZ. GlmZ activates the glmS mRNA by base-pairing. When not required, GlmZ is bound by adapter protein RapZ and recruited to cleavage by RNase E inactivating the sRNA. The homologous sRNA GlmY activates...
-
Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis
PublicationCancer continues to be a leading cause of death worldwide, making the development of new treatment methods crucial in the fight against it. With cancer incidence rates increasing worldwide, ongoing research must focus on identifying new and effective ways to prevent and treat the disease. The combination of herbal extracts with chemotherapeutic agents has gained much interest as a novel strategy to combat cancer. Rumex obtusifolius...
-
Rotation Triggers Nucleotide-Independent Conformational Transition of the Empty β Subunit of F1-ATPase
PublicationF1-ATPase (F1) is the catalytic portion of ATP synthase, a rotary motor protein that couples proton gradients to ATP synthesis. Driven by a proton flux, the F1 asymmetric γ subunit undergoes a stepwise rotation inside the α3β3 headpiece and causes the β subunits’ binding sites to cycle between states of different affinity for nucleotides. These concerted transitions drive the synthesis of ATP from ADP and phosphate. Here, we study...
-
Syntheses, structures and chemical properties of unsaturated oligo(alkylene-ester-ether)diols
Publication -
The Syntheses and Crystal Structures of the First Disiloxane-1,3-dithiol and Its Cadmium Complex.
PublicationThe new silicon–sulfur compound: disiloxane-1,3-dithiol was obtained from silicon disulfide and 2,6-diisopropylphenol in a reaction catalyzed by imidazole or 4-(dimethylamino)pyridine (DMAP). Crystal structure of disiloxane–1,3-dithiol reveals a close-to-linear Si–O–Si angle and a mutual trans position of the two hydrosulfido groups. The compound forms a chelating mononuclear complex with cadmium ions.
-
A Convenient Way to Methylated 2-Imidazolines. Syntheses of Fluorene and Triazine Cyclic Diamidines
PublicationOne N-methyl- and 4-substituted 2-imidazolines are described. Fluorene bisimidazolines were obtained in good yield (64-92%), starting from 2,7-dicyanofluorene and ammonium sulfide. In a two-step procedure the crude bisthioamide was reacted with excess diaminoalkane-ethanol (1:1 mixt.) in an oil bath. This new procedure is superior over std. methods. For the sake of comparison, a new triazine bisimidazoline (I) was prepd. by...
-
Convenient Syntheses of N-Methylthioamides: A Migration of the H2S Molecule in the Thioamide-nitrile System
PublicationThe reaction of thioamides with the R1R2N-ZnCl ammoniates leads to N-mono-, N,N'-di-, N,N-disubstituted, and unsubstituted amidines with high concns. of amines in abs. ethanol. The efficient direct formation of the N,N'-dimethylamidine can be explained by a greater reactivity of methylamine compared with dimethylamine. Discovery of a new zwitterion (induced by a carbonyl oxygen) suggests that the stabilization in the thymine...
-
Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids
Publication -
Public Perception of Digital Contact Tracing App and Implications for Technology Acceptance and Use Models
PublicationGovernments are increasingly adopting digital contact tracing applications (DCT) as a key component of their response to the COVID-19 pandemic. However, governments are struggling to achieve widespread adoption of DCT necessary for obtaining the expected individual and public benefits associated with its use. Consequently, studies on DCT have focused on the barriers to DCT adoption in different contexts and possible ways of overcoming...
-
Molecular dynamics study on the role of solvation water in the adsorption of hyperactive AFP to the ice surface
PublicationUsing computer simulations, the early stages of the adsorption of the CfAFP molecule to the ice surface were analyzed. We found that the ice and the protein interact at least as early as when the protein is about 1 nm away from the ice surface. These interactions are mediated by interfacial solvation water and are possible thanks to the structural ordering of the solvent. This ordering leads to positional preference of the protein...
-
Subjective Preferences Towards Various Conditions of Self-Administered Questionnaires: AHP and Conjoint Analyses
Publication -
Investigation ofcis/trans ratios of peptide bonds in AVP analogues containingN-methylphenylalanine enantiomers
Publication -
Design and thermodynamic analysis of an H2O–LiBr AHP system for naval surface ship application
Publication -
Molecular picture of hydroxide anion hydration in aqueoussolutions studied by FT-IR ATR spectroscopy
PublicationHydratacja anionu hydroksylowego w wodnych roztworach wodorotlenków metali alkalicznych (LiOH, NaOH, KOH) została zbadana metodą spektroskopii oscylacyjnej FT-IR całkowitego wewnętrznego odbicia (ATR). Widma oscylacyjne wody dostarczają cennych informacji na temat stanu strukturalnego cząsteczek wody w sferach hydratacyjnych, wynikających ze sprzężeń oscylatorów w układzie. Wykazano, że drganie normalne rozciągające cząsteczki...
-
Metody walki z prowizorycznymi urządzeniami wybuchowymi w świetle doktryny AJP-3.15
PublicationW artykule przedstawiono założenia doktryny AJP-3.15, dotyczącej metod walki z prowizorycznymi urządzeniami wybuchowymi. Scharakteryzowano zagrożenia związane z IED oraz szczegółowo omówiono sposoby ich likwidacji i minimalizacji skutków ich użycia. Na tym tle, w skrócie zaprezentowano propozycję nowego systemu ochrony obiektów mobilnych przed tego typu atakami.
-
Zastosowanie metody AHP do porównania kryteriów wyboru lokalizacji budowy farmy wiatrowej
PublicationW artykule przedstawiono opis oraz porównanie kryteriów wyboru lokalizacji farmy wiatrowej. Kryteria te uwzględniają pomiary wietrzności na rozpatrywanym terenie, lokalizację turbin wiatrowych, lokalizację linii elektroenergetycznej służącej do przesyłu wyprodukowanej energii elektrycznej od farmy wiatrowej do stacji elektroenergetycznej (GPZ), infrastrukturę towarzyszącą, warunki techniczne przyłączenia do sieci elektroenergetycznej...
-
Zastosowanie metody AHP do porównania kryteriów wyboru lokalizacji budowy farmy wiatrowej
PublicationArtykuł przedstawia opis oraz porównanie kryteriów wyboru lokalizacji farmy wiatrowej. Kryteria te uwzględniają pomiary wietrzności na rozpatrywanym terenie, lokalizację turbin wiatrowych, lokalizację linii elektroenergetycznej służącej do przesyłu wyprodukowanej energii elektrycznej od farmy wiatrowej do stacji elektroenergetycznej (GPZ), infrastrukturę towarzyszącą, warunki techniczne przyłączenia do sieci elektroenergetycznej...
-
Short Term Monitor of Photodegradation Processes in Ranitidine Hydrochloride Observed by FTIR and ATR FTIR
PublicationThe effects of degradation of ranitidine hydrochloride exposed to UVB radiation (l = 310 nm) and oxygen in a weathering chamber were studied by Fourier Transform Infrared spectroscopy (FTIR) and Attenuated Total Reflectance Fourier Transform Infrared spectroscopy (ATR-FTIR). ATR-FTIR profile indicated that the degradation was spatially heterogeneous. Significant amounts of photoproducts were detected only in a directly...
-
Spektroskopia refleksyjna w podczerwieni (ATR-FTIR) w aspekcie badań trwałości leku
Publication -
Lean Startup as a New Way of Managing Technology Ventures Illustrated by the Example of Wlcome App
PublicationThe dot-com bubble in the 1990s made the technology industry aware that even excellent ideas backed by amazing teams are not sufficient to ensure a startup’s success. The biggest risk of startups is that they have to operate within many uncertainties, their market and customers are unknown, and their business model is not yet validated. Therefore, successful execution of such a venture requires a rigorous process that would validate...
-
Analysis of the impact of AOP on source code quality: Paradox of aspect-oriented separation of concerns
PublicationAlmost four decades ago, Parnas advocated modularity for the sake of changeability, independent development, and comprehensibility. The recipe for modularization is to define a clean interface, hide an implementation detail, keep low coupling and high cohesion. Although modules have taken many forms over the years from functions and procedures to classes, no form has been capable of expressing so-called crosscutting concerns in...
-
Degradation of bisphenol S – a contaminant of emerging concern - by synergistic ozone and percarbonate based AOP
PublicationDegradation of bisphenol S was studied using ozone activated by sodium percarbonate and the effectiveness of optimized process was compared with the peroxone process. The influence of several factors including sodium percarbonate concentration, ozone dose, pH, and water matrix were investigated. A synergetic coefficient of 3.84 was achieved for the combination of sodium percarbonate and ozone, confirming the effectiveness of this...
-
Zastosowanie spektroskopii ATR/FT-IR w badaniach polimerów zawierających ugrupowania pirolidonowe
PublicationW niniejszej pracy prezentujemy syntezę i analizę właściwości fizyko-chemicznych porowatych mikrosfer zawierających ugrupowania pirolidonowe otrzymanych technika suspensyjną. Ugrupowania pirolidonowe zostały wprowadzone w sieć polimerową w wyniku bezpośredniej reakcji z 1-winylo-2-pirolidonem (VP) z dimetakrylanem glikolu etylenowego (DMGE) oraz poprzez modyfikację pirolidonem grup epoksydowych obecnych w strukturze kopolimeru...
-
Enhancing environmental literacy through urban technology-based learning. The PULA app case
PublicationThis study addresses the need to enhance environmental literacy, focusing on urban adults through mobile applications, based on the example of PULA app that engages early adopters in gamified pro- environmental activities, offering insights into informal learning. Grounded in 'urban pedagogy,' the study combines semi-structured interviews with 17 application testers and quantitative data analysis, unveiling motivations, user feedback,...