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Wyniki wyszukiwania dla: ORGANIC PHOTOVOLTAIC CELL, PLANAR HETEROJUNCTION, SHOCKLEY-QUEISSER LIMIT, CHARGE TRANSPORT, EXCITONIC PHOTOVOLTAIC CELL
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Muscle Cell Morphogenesis, Structure, Development and Differentiation Processes Are Significantly Regulated during Human Ovarian Granulosa Cells In Vitro Cultivation
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Piperine Targets Different Drug Resistance Mechanisms in Human Ovarian Cancer Cell Lines Leading to Increased Sensitivity to Cytotoxic Drugs
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The Significance of MicroRNAs Expression in Regulation of Extracellular Matrix and Other Drug Resistant Genes in Drug Resistant Ovarian Cancer Cell Lines
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Assessment of immunomodulation and regulation of cell cycle in epithelium and stroma after Cidofovir injection in patients with recurrent respiratory papillomatosis—Pilot study
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The extended version of restriction analysis approach for the examination of the ability of low-molecular-weight compounds to modify DNA in a cell-free system
PublikacjaOne of the primary requirements in toxicology is the assessment of ability of chemicals to induce DNA covalent modification. There are several well-established methods used for this purpose such as 32P-Postlabeling or HPLC-MS. However, all of these approaches have difficult to overcome limitations, which prevents their use in genotoxin screening. Here, we describe the simple protocol exploiting specificity of restriction enzymes...
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Increased susceptibility of PARP-1 KO cells to antitumor triazoloacridone C-1305 is associated with permanent G2 cell cycle arrest.
PublikacjaTriazoloakrydon C-1305 jest nowym inhibitorem topoizomerazy II wykazującym wysoką aktywność przeciwnowotworową. W tej pracy badaliśmy działanie cytotoksyczne pochodnej C-1305 i jej analogu strukturalnego C-1533 wobec komórek fibroblastów mysich i dwóch mutantów, w których uszkodzono gen PARP-1. Jak wykazaliśmy, komórki z uszkodzonym genem PARP-1 są nadwrażliwe na działanie związku C-1305 w porównaniu z komórkami PARP-1 +/+ podczas...
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The influence of 4-substituted and unsubstituted derivatives of 1-nitroacridine on the cell cycle and induction of apoptosis in human cancer HT29 and HeLa S3.
PublikacjaZbadano wpływ pochodnych 1-nitroakrydyny C-1748 i C-857, w stężeniach biologicznie istotnych, na cykl życiowy oraz indukcję apoptozy komórek raka jelita grubego HT29 oraz raka szyjki macicy HeLa S3. Metodą cytometrii przepływowej wykazano, że 4-metylo-1-nitroakrydyna C-1748 powoduje akumulację komórek HT29 w fazie S i komórek HeLa S3 w fazie G2 cyklu komórkowego zaś związek C-857 indukuje akumulację komórek HT29 i HeLa S3 w fazie...
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One-tube cell lysis and DNA extraction procedure for PCR based detection of Mycobacterium ulcerans in aquatic insects, molluscs and fish.
PublikacjaMycobacterium ulcerans jest bakterią wywołującą choroby skóry u ludzi i zwierząt. W trakcie prowadzonych badań opracowano prostą w wykonaniu metodę ekstrakcji DNA Mycobacterium ulcerans z próbek środowiskowych oraz klinicznych. Opracowana metoda izolacji DNA może być przydatna w badaniu źródeł infekcji oraz dróg szerzenia się Mycobacterium ulcerans.
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Osteoblast and bacterial cell response on RGD peptide‐functionalized chitosan coatings electrophoretically deposited from different suspensions on Ti13Nb13Zr alloy
PublikacjaMetallic materials for long-term load-bearing implants still do not provide high antimicrobial activity while maintaining strong compatibility with bone cells. This study aimed to modify the surface of Ti13Nb13Zr alloy by electrophoretic deposition of a chitosan coating with a covalently attached Arg-Gly-Asp (RGD) peptide. The suspensions for coating deposition were prepared in two different ways either using hydroxyacetic acid...
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Biochar-mediated transformation of titanium dioxide nanoparticles concerning TiO2NPs-biochar interactions, plant traits and tissue accumulation to cell translocation
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C-Reactive Protein and White Blood Cell Count in Non-Infective Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis
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SMART GRID TECHNOLOGIES IN ELECTRIC POWER SUPPLY SYSTEMS OF PUBLIC TRANSPORT
PublikacjaNowadays the issue of electric energy saving in public transport is becoming a key area of interest, which is connected both with a growth in environmental awareness of the society and an increase in the prices of fuel and electricity. It can be achieved by reducing the transmission losses in a supply system or by the improving the usage of the regenerative breaking. The article presents an analysis of applying these two options...
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SMART GRID TECHNOLOGIES IN ELECTRIC POWER SUPPLY SYSTEMS OF PUBLIC TRANSPORT
PublikacjaNowadays the issue of electric energy saving in public transport is becoming a key area of interest which is connected both with a growth in environmental awareness of the society and an increase in the prices of fuel and electricity. It can be achieved by reducing of the transmission losses in supply system or by the improving of the usage of the regenerative breaking. The article presents an analysis of applying these two options...
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Developing a Metropolitan Transport System—Exemplified by the Gdansk–Gdynia–Sopot Metropolitan Area
PublikacjaAs regional centres with metropolitan functions, metropolises grow and develop depending on how well they can meet the area’s transport needs internally and externally, a result of their socio-economic relations. The transport system of a metropolitan area must ensure that people and goods can move efficiently, effectively and environmentally friendly. Over the last ten years, the transport system of the Gdańsk–Gdynia–Sopot Metropolitan...
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CYP3A4-dependent cellular response does not relate to CYP3A4-catalysed metabolites of C-1748 and C-1305 acridine antitumor agents in HepG2 cells
PublikacjaHigh CYP3A4 expression sensitizes tumor cells to certain antitumor agents while for others it can lower their therapeutic ef fi cacy. We have elucidated the in fl uence of CYP3A4 overexpression on the cellular response induced by antitumor acridine derivatives, C-1305 and C-1748, in two hepatocellular carcinoma (HepG2) cell lines, Hep3A4 stably transfected with CYP3A4 isoenzyme, and HepC34 expressing empty vector. The compounds...
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Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers
PublikacjaMultidrug resistance (MDR) remains a primary hindrance to curative cancer therapy. Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance. Sequestration of chemotherapeutics in lysosomes is an established mechanism of drug resistance. Here, we show that MDR cells display a marked increase in lysosome number. We further demonstrate that imidazoacridinones (IAs), which are cytotoxic fluorochromes,...
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PROGRAMMABLE YANG - BASED INTERFACE IN CONTROL OF OPTICAL TRANSPORT NETWORK
PublikacjaSince over a decade we observe intensive effort of research institutions and industrial consortia on extending flexibility and automation of the transport network control also known under the term network programmability. Key aspect of each programming interface is ability to evolve but also sensitivity to future modifications. As indicated in the past work in the specific context of optical transport networks an important criterion...
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Nutrient transport and acquisition by diatom chains in a moving fluid
PublikacjaThe role of fluid motion in delivery of nutrients to phytoplankton cells is a fundamental question in biological and chemical oceanography. In the study of mass transfer to phytoplankton, diatoms are of particular interest. They are non-motile, are often the most abundant components in aggregates and often form chains, so they are the ones expected to benefit most from enhancement of nutrient flux due to dissipating turbulence....
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Preferences and Transport Behavior of Gdansk Residents in the Light of the Result of Complex Traffic Survey
PublikacjaPreferences and transport behavior of the population are a fundamental aspect of research in public transport. Identifying the basic postulates of transport, the factors determining the specific behavior of transport and modal split allow to analyze the differences between the groups singled passengers and to prepare better offer of an urban transport. In Poland, still in many cities urban transport research is conducted ad hoc,...
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THE OPPORTUNITY FOR THE DEVELOPMENT OF TROLLEYBUS TRANSPORT WITH THE SUPPORT OF EUROPEAN UNION FOUNDS
PublikacjaThe article introduced the development of trolleybus transport in Poland during the last 10 years. Development that took place was wi support of the European Union.
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Pilot-Scale Studies of WO3/S-Doped g-C3N4 Heterojunction toward Photocatalytic NOx Removal
PublikacjaDue to the rising concentration of toxic nitrogen oxides (NOx) in the air, effective methods of NOx removal have been extensively studied recently. In the present study, the first developed WO3/S-doped g-C3N4 nanocomposite was synthesized using a facile method to remove NOx in air efficiently. The photocatalytic tests performed in a newly designed continuous-flow photoreactor with an LED array and online monitored NO2 and NO system...
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Design and Application of Magnetic Photocatalysts for Water Treatment. The Effect of Particle Charge on Surface
PublikacjaCore-interlayer-shell Fe3O4/SiO2/TiO2, CoFe2O4/SiO2/TiO2 and BaFe12O19/SiO2/TiO2 magnetic photocatalysts were obtained. A water-in-oil microemulsion system with suitable surfactants was used for functionalization of the magnetic core with silica interlayer and TiO2-based photocatalyst. Uncoated and coated particles were characterized by electrophoretic meaurements, X-ray diffractometry (XRD), scanning electron microscopy (SEM),...
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Functionalized nanodiamonds as a perspective green carbo-catalyst for removal of emerging organic pollutants
PublikacjaRapid industrial and urban development jointly with rising global population strongly affect the large-scale issues with drinking, groundwater, and surface water pollution. Concerns are not limited to environmental issues but also human health impact becoming serious global aspect. Organic pollution becomes a primarily serious hazard, therefore, the novel sophisticated approaches to treat them are thoroughly investigated. Among...
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Generation of charge carriers pairs in tetracene.
PublikacjaBadano mechanizmy odpowiedzialne za fotogenerację nośników ładunku w polikrystalicznych warstwach tetracenu.
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Implementation of Solute Transport in the Vadose Zone into the “HYDRUS Package for MODFLOW”
PublikacjaThe “HYDRUS package for MODFLOW” is an existing MODFLOW package that allows MODFLOW to simultaneously evaluate transient water flow in both unsaturated and saturated zones. The package is based on incorporating parts of the HYDRUS‐1D model (to simulate unsaturated water flow in the vadose zone) into MODFLOW (to simulate saturated groundwater flow). The coupled model is effective in addressing spatially variable saturated‐unsaturated...
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BODIPY‐Perylene Charge Transfer Compounds; Sensitizers for Triplet‐Triplet Annihilation Up‐conversion
PublikacjaBODIPY heterochromophores, asymmetrically substituted with perylene and/or iodine at the 2 and 6 positions were prepared and investigated as sensitizers for triplet-triplet annihilation up conversion (TTA-UC). Single-crystal X-ray crystallographic analyses show that the torsion angle between BODIPY and perylene units lie between 73.54 and 74.51, though they are not orthogonal. Both compounds show intense, charge transfer absorption...
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Fixed points of planar homeomorphisms of the form Identity + Contraction
PublikacjaW pracy dowodzi się, przy użyciu indeksu, istnienia punktów stałych dla planarnych homeomorfizmów, których orbity spełniają pewien geometryczny warunek.
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Compact Planar Balun for the UWB Dipole Feeding Network
PublikacjaW pracy opisano wyniki z badań numerycznych ultra szerokopasmowego symetryzatora planarnego o zredukowanych wymiarach. Układ został zaprojektowany w oparciu o konfigurację opisaną w literaturze. Względem konfiguracji bazowej, układ przeprojektowano na inne podłoże. W celu weryfikacji przydatności układu, przeprowadzono symulację anteny dipolowej zasilanej opisywanym symetryzatorem. Na podstawie otrzymanych rezultatów przekazano...
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Resonant and nonresonant excitation of waves in a planar magnetosonic flow
PublikacjaForced propagation of perturbations in a magnetosonic wave are considered. The driving force may be caused by stimulated Mandelstam–Brillouin scattering of optic waves or by intense magnetosonic exciter. Some heating-cooling function which takes into account radiative cooling and unspecified heating is taken into consideration, as well as nonlinearity of a medium. Both these factors make the excitation particular. The analytical...
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Local fixed point indices of iterations of planar maps
PublikacjaW artykule podana zostaje postać indeksów iteracji dla pewnej klasy odwzorowań planarnych. Podstawowymi narzędziami stosowanym w pracy są liczba Nielsena i indeks Conleya.
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Assessment of fitness for service of Cr-Mo steel tubes in catalytic reforming charge heaters
PublikacjaIn this paper characteristic features of metal dusting corrosion in high temperature gas mixtures of high carbon activity in catalytic reforming units, including Continuous Catalyst Regeneration (CCR) platformer are presented. Examples of 2.25Cr-1Mo and 9Cr-1Mo steel tubes at advanced stages of metal dusting process after long-term service in charge heaters are used to prove that destructive examinations are necessary to provide...
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A modelling approach to the transport support for the harvesting and transportation complex under uncertain conditions
PublikacjaThe article proposes a modelling approach based on structural and parametric identification of the transport support of the harvesting and transportation complex. The efficiency and effectiveness of the proposed methods of structural and parametric identification for the development of a system for harvesting and transportation complex operation has been proved. A mathematical model based on fuzzy logic has been developed. It reflects...
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Spectral dependences of photocurrent of the aluminium-nickel phthalocyanine-tetracene-aluminium heterojunction
PublikacjaAnalizowano charakterystyki spectralne fotoprądu płynącego przez heterozłącze tetracen-ftalocyjanina niklu. Obserwowany fotoprąd jest prądem dziurowym generowanym w trzech obszarach: w pobliżu obu elektrod Al i międzypowierzchni tetracen-ftalocyjanina niklu.
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Hopping or Tunneling? Tailoring the Electron Transport Mechanisms through Hydrogen Bonding Geometry in the Boron-Doped Diamond Molecular Junctions
PublikacjaMechanisms of charge transport in molecular junctions involving hydrogen bonds are complex and remain mostly unclear. This study is focused on the elucidation of the electron transfer in a molecular device consisting of two boron-doped diamond interfaces bound with an aromatic linker and a hydrogen bonding surrogating molecule. The projected local density of states (PLODS) analysis coupled with transmission spectra and current−voltage...
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Implementation of IMS/NGN Transport Stratum Based on the SDN Concept
PublikacjaThe paper presents the development and verification of software and a testbed aiming to demonstrate the ability of two telecommunication network concepts—Next Generation Network (NGN) and Software-Defined Networking (SDN)—to cooperate. The proposed architecture includes components of the IP Multimedia Subsystem (IMS) in its service stratum and of the SDN (controller and programmable switches) in its transport stratum, providing...
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Impact of Intelligent Transport Systems Services on the Level of Safety and Improvement of Traffic Conditions
PublikacjaThe positive effects of the services of Intelligent Transport Systems (ITS) on the level of transport systems operation was confirmed by long-term studies conducted, inter alia, in the USA, Japan and Europe. Benefits resulting from the application of ITS services can be presented through performance indicators. The indicators represent in a numerical or qualitative manner to what extent ITS services can contribute to improving...
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Probabilistic limit state analysis of framed structures. The Monte Carlo simulation.
PublikacjaW pracy opisano koncepcję rozkładu prawdopodobieństwa stanu granicznego konstrukcji. Koncepcja ta oparta jest na problemowo zorientowanej procedurze symulacyjnej Monte Carlo. Niezawodnosć lub prawdopodobieństwo awarii układu oblicza się na podstawie rozkładu prawdopodobieństwa stanu granicznego.
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Probabilistic limit state analysis of framed structures. The Monte Carlo simulation.
PublikacjaW pracy opisana jest koncepcja rozkładu prawdopodobieństwa stanu granicznego konstrukcji, oparta na specjalnej procedurze symulacyjnej Monte Carlo. Główną ideę stanowi obliczenie mnożnika obciażenia granicznego w każdym kroku symulacyjnym. Niezawodnosć lub prawdopodobieństwo awarii konstrukcji sa charakterystykami rozkładu prawdopopdobieństwa stanu granicznego. Szczegółowo opisano dwa warianty symulacji.
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Probability of limit state of bar structures. A modified Monte Carlo procedure
PublikacjaPraca poświecona jest zagadnieniom niezawodności i probabilistycznej analizie stanów granicznych układów prętowych. Główną ideę pracy stanowi rozkład prawdopodobieństwa stanu granicznego nośności ustroju, zdefiniowany na podstawie specjalnej procedury symulacyjnej Monte Carlo. W procedurze tej istotne jest wyznaczanie mnożników obciążenia granicznego w każdym kroku symulacyjnym. Charakterystykami rozkładu prawdopodobieństwa stanu...
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New Polymethoxyflavones from Hottonia palustris Evoke DNA Biosynthesis-Inhibitory Activity in An Oral Squamous Carcinoma (SCC-25) Cell Line
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Viability and intracellular nitric oxide generation in the umbilical cord blood CD34+CD133– and CD34+CD133+ cell populations exposed to local anaesthetics
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Prospective subgroup analyses of the randomized MCL-002 (SPRINT) study: lenalidomide versus investigator's choice in relapsed or refractory mantle cell lymphoma
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Lenalidomide versus investigator's choice in relapsed or refractory mantle cell lymphoma (MCL-002; SPRINT): a phase 2, randomised, multicentre trial
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Prospective study of brentuximab vedotin in relapsed/refractory Hodgkin lymphoma patients who are not suitable for stem cell transplant or multi-agent chemotherapy
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Outcome and prognostic factors in advanced Hodgkin's disease treated with high-dose chemotherapy and autologous stem cell transplantation: a study of 341 patients
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Efficacy of high-dose corticosteroid-based treatment for chronic lymphocytic leukemia patients with p53 abnormalities in the era of B-cell receptor inhibitors
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Synthesis of 7-oxo-7h-naphto[1,2,3-de]quinoline derivatives as potential anticancer agents active on multidrug resistant cell lines
PublikacjaOpierając się na naszym wcześniejszym stwierdzeniu, że tetracykliczne analogi antrachinonów z wbudowanym pierścieniem pirydynowym wykazują aktywną cytotoksyczność względem komórek z indukowaną opornością, przeprowadzono syntezę pochodnych 7-oxo-7h-nafto[1,2,3-de]chinoliny (3, 6-8, 10-12, 14,15 i 18) posiadających jeden lub dwa zasadowe łańcuchy boczne i różne podstawniki w pierścieniu pirydynowym, związków o potencjalnym działaniu...
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Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development
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‘Heart development and morphogenesis’ is a novel pathway for human ovarian granulosa cell differentiation during long‑term in�vitro cultivation‑a microarray approach
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Combination of ABT-737 and resveratrol enhances DNA damage and apoptosis in human T-cell acute lymphoblastic leukemia MOLT-4 cells
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