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Wyniki wyszukiwania dla: BLOOD BACTERICIDAL ACTIVITY
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The Chemometric Evaluation of Antitumor Activity of Novel Benzensulfonamide Derivatives Based on their Physiochemical Properties
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Biological Activity of Compounds Exhibiting Local Anesthetics's Properties Evaluated by QSAR Approach
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Variation in Total Polyphenolics Contents of Aerial Parts of Potentilla Species and Their Anticariogenic Activity
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Activity evaluation of some psychoactive drugs with the application of QSAR/QSPR modeling methods
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Preparation of silver nanoparticles in reverse micelles and antibacterial activity of silver modified-paints
PublikacjaW publikacji została opisana metoda otrzymywania nanocząstek srebra oraz farb modyfikowanych srebrem i ich wpływ na zahamowanie rozwoju wybranych bakterii i grzybów. Podjęto również próbę porównania wpływu rodzaju prekursora srebra oraz substancji powierzchniowo czynnej na stabilność otrzymanych nanocząstek srebra. Przygotowane mikroemulsje zawierały od 500 do 2000 ppm srebra
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Electrochemical activity of composite material poly(3,4-ethylenedioxythiophene) modified by silver hexacyanoferrate
PublikacjaW pracy przedstawiono sposób slektrochemicznj syntezy materiału składającego się z polimeru przewodzącego poli(3,4-etylenodioksytiofen) (pEDOT) i nieorganicznej sieci typu redox heksacyjanożelazianu srebra (Aghcf). Materiał otrzymano na drodze dwuetapowej. Etap pierwszy polega na galwanostatycznej redukcji srebra na elektrodzie z węgla szklistego. Etap drugi to roztwarzanie srebra z jednoczesną polimeryzacją monomeru. Otrzymany...
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Comparison of the contents of bioactive compounds and the level of antioxidant activity in different kiwifruit cultivars
PublikacjaGłównym celem prowadzonych badań było stwierdzenie która z odmian owoców kiwi (''Hayward'', ''Daeheuhg'', ''Haenam'' oraz ''Bidan'') jest najbardziej odpowiednią z punktu widzenia konsumpcji przez człowieka. Z tego powodu w odpowiednio przygotowanych próbkach ekstraktów z owoców kiwi oznaczono:- profile związków bioaktywnych;- poziomy aktywności przeciwutleniającej. Wyniki pomiarów zawartości polifenoli (flawonoidy oraz kwasy fenolowe)...
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Developments in the synthesis and biological activity of Glycyl-L-Histydyl-L-Lysine derivatives
PublikacjaWe emphasize on the methods of the synthesis described in the literature and present the aspects of Gly-His-Lys structure modifications that played a key role in scientific research.
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Activity of isavuconazole and other triazole derivatives against clinical isolates of Aspergillus fumigatus
PublikacjaAspergillus fumigatus is the most frequent pathogen of the genus Asperillus, which is highly susceptible to triazole derivatives, especially to isavuconazole and voriconazole. Many countries face a growing problem of infections due to A. fumigatus showing acquired resistance to one or several triazoles. In medical centres, monitoring the susceptibility of isolated Aspergillus spp. is recommended. The aim of this study was to collect...
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Influence of Annealing Atmospheres on Photoelectrochemical Activity of TiO2 Nanotubes Modified with AuCu Nanoparticles
PublikacjaIn this article, we studied the annealing process of AuCu layers deposited on TiO2 nanotubes (NTs) conducted in various atmospheres such as air, vacuum, argon, and hydrogen in order to obtain materials active in both visible and UV–vis ranges. The material fabrication route covers the electrochemical anodization of a Ti plate, followed by thin AuCu film magnetron sputtering and further thermal treatment. Scanning electron microscopy...
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Encapsulation of Cs3Bi2Br9 perovskite photocatalyst with polythiophene for prolonged activity in oxidizing and humid environment
PublikacjaDespite their growing popularity in modern technology, halide perovskites suffer from susceptibility to oxidation, limiting their applications. Our aim was to enhance Cs3Bi2Br9 perovskite's performance in humid environments through polythiophene encapsulation. This extended its lifespan while preserving photocatalytic abilities, as demonstrated in toluene decomposition experiments. We confirmed the stability of Cs3Bi2Br9 encapsulated...
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Measuring pulse rate with a webcam — A non-contact method for evaluating cardiac activity
PublikacjaIn this paper the simple and robust method of measuring the pulse rate is presented. Elaborated algorithm allows for efficient pulse rate registration directly from face image captured from webcam. The desired signal was obtained by proper channel selection and principal component analysis. A developed non-contact method of heart rate monitoring is shown in the paper. The proposed technique may have a great value in monitoring...
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Catalytic activity of Ni-MgAl2O4 modified with transition metal (Ti, Mo, W) carbides as potential catalysts for resource recovery via dry reforming of waste plastics
PublikacjaThe growing amounts of plastic waste and CO2 emissions are two environmental threats that require urgent attention. Pyrolysis combined with dry reforming (PCDR) is a technology that allows both CO2 utilization and resource recovery from waste plastic. New catalysts for PCDR are crucial for developing efficient and stable processes that can be widely implemented in the industry. In this study, Ni/MgAl2O4 catalysts modified using different...
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Insightful studies of AuCu nanostructures deposited on Ti platform: Effect of rapid thermal annealing on photoelectrochemical activity supported by synchrotron radiation studies
PublikacjaIn this work, we present the influence of annealing atmospheres during rapid thermal annealing (40◦C/s) on nanostructured Ti platforms modified by 10 nm layer of AuCu alloy obtained via magnetron sputtering. The AuCu/Ti platform annealed under hydrogen atmosphere exhibits the best photoelectrochemical activity under visible light, i.e. 27 times higher photocurrent than for pure Ti dimpled platform, and the lowest reflectance with minimum...
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Hydrothermal modification of TiO2 nanotubes in water and alkali metal electrolytes (LiNO3, NaNO3, KNO3) – Direct evidence for photocatalytic activity enhancement
PublikacjaThe influence of hydrothermal annealing (HA) of TiO2 nanotubes (TiO2-NTs) in various baths (H2O, LiNO3, NaNO3, KNO3 performed for 4 h, 24 h, 64 h), on their photocatalytic and photoelectrocatalytic properties, was studied. The use of electrolytes was to enable the monitoring of photoactivity changes as a result of the expected impact on the population of hydroxyl groups on the surface. The assumption turned out to be correct and...
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Effects of Post-Harvest Elicitor Treatments with Ultrasound, UV- and Photosynthetic Active Radiation on Polyphenols, Glucosinolates and Antioxidant Activity in a Waste Fraction of White Cabbage (Brassica oleracea var. capitata)
PublikacjaBiosynthesis of phytochemicals in leaves of Brassica can be initiated by abiotic factors. The aim of the study was to investigate elicitor treatments to add value to waste of cabbage. A leaf waste fraction from industrial trimming of head cabbage was exposed to UV radiation (250–400 nm, 59 and 99 kJ m-2, respectively), photosynthetic active radiation (PAR, 400–700 nm, 497 kJ m-2), and ultrasound in water bath (35 kHz, at 15, 30...
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The overexpression of CPR and P450 3A4 in pancreatic cancer cells changes the metabolic profile and increases the cytotoxicity and pro-apoptotic activity of acridine antitumor agent, C-1748
PublikacjaDrug resistance is one of the major cause of pancreatic cancer treatment failure. Thus, it is still imperative to develop new active compounds and novel approach to improve drug efficacy. Here we present 9-amino-1-nitroacridine antitumor agent, C-1748, developed in our laboratory, as a candidate for pancreatic cancer treatment. We examined (i) the cellular response of pancreatic cancer cell lines: Panc-1, MiaPaCa-2, BxPC-3 and...
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Antitumor Activity of Triazine Mimic Antibiotics for DNA-binding Implications (Impressive Activity in Vitro Against a Variety of Tumor Types in the NCI-60 Screen): NSC 710607 To Fight HCT-116 Human Colon Carcinoma Cell Lines in Vivo Using the Hollow Fiber Assay and Xenograft Mouse Models
PublikacjaPurpose Successful clinical applications of DNA-directed selective cytotoxic agents disrupt the vital replication/transcription processes and ultimately lead to cancer cell death. This study aimed to examine the growth screen of two lead triazine compounds in a number of cell lines and xenografts and to develop anticancer agents with noncovalent binding affinity bringing fewer side effects. Methods The NCI initial hollow...
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Human red blood cells targeted metabolome analysis of glycolysis cycle metabolites by capillary electrophoresis using an indirect photometric detection method
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Replication of hepatitis C virus in peripheral blood mononuclear cells in patients with chronic hepatitis C treated with pegylated interferon alpha and ribavirin
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Current understanding of the effects of inspiratory resistance on the interactions between systemic blood pressure, cerebral perfusion, intracranial pressure, and cerebrospinal fluid dynamics
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Blood pressure control and cardiovascular risk profile in hypertensive patients from central and eastern European countries: results of the BP-CARE study
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Ambulatory Systolic Blood Pressure is Related to the Deletion Allele of the Angiotensin I Converting Enzyme Gene in Young Normotensives with Parental History of Hypertension
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Corrigendum to “Blood pressure disturbances and endothelial dysfunction markers in children and adolescents with type 1 diabetes” [Atherosclerosis 237 (2014) 129–134]
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New Gene Markers of Angiogenesis and Blood Vessels Development in Porcine Ovarian Granulosa Cells during Short-Term Primary Culture In Vitro
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Blood free Radicals Concentration Determined by Electron Paramagnetic Resonance Spectroscopy and Delayed Cerebral Ischemia Occurrence in Patients with Aneurysmal Subarachnoid Hemorrhage
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Viability and intracellular nitric oxide generation in the umbilical cord blood CD34+CD133– and CD34+CD133+ cell populations exposed to local anaesthetics
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Validated HPTLC method for determination of ledol and alloaromadendrene in the essential oil fractions of Rhododendron tomentosum plants and in vitro cultures and bioautography for their activity screening
PublikacjaRhododendron tomentosum (Ledum palustre) is a bog shrub used in traditional medicine for treatment of respiratory and rheumatic diseases. Due to the large variability of the chemical composition of its essential oil, depending on the habitat, the in vitro cultures were established as the alternative source of the volatile fraction. There is a need to monitor a quality of the field grown as well as in vitro plant material, especially...
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Synthesis of 3-(2-Alkylthio-4-chloro-5-methylbenzenesulfonyl)-2-(1-phenyl-3-arylprop-2-enylideneamino)guanidine Derivatives with Pro-Apoptotic Activity against Cancer Cells
PublikacjaThe untypical course of reaction between chalcones and benzenesulfonylaminoguanidines led to the new 3-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-2-(1-phenyl-3-arylprop-2- enylideneamino)guanidine derivatives 8–33. The new compounds were tested in vitro for their impact on the growth of breast cancer cells MCF-7, cervical cancer cells HeLa and colon cancer cells HCT-116 by MTT assay. The results revealed that the activity of...
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Novel 2-alkythio-4-chloro-N-[imino(heteroaryl)methyl]benzenesulfonamide Derivatives: Synthesis, Molecular Structure, Anticancer Activity and Metabolic Stability
PublikacjaA series of novel 2-alkythio-4-chloro-N-[imino-(heteroaryl)methyl]benzenesulfonamide derivatives, 8–24, were synthesized in the reaction of the N-(benzenesulfonyl)cyanamide potassium salts 1–7 with the appropriate mercaptoheterocycles. All the synthesized compounds were evaluated for their anticancer activity in HeLa, HCT-116 and MCF-7 cell lines. The most promising compounds, 11–13, molecular hybrids containing benzenesulfonamide...
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Antimicrobial Activity of Selected Antimicrobial Peptides Against Planktonic Culture and Biofilm of Acinetobacter baumannii
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Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats
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Characteristic of antioxidant activity of dry-cured pork loins inoculated with probiotic strains of LAB
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Application of Rotating Magnetic Fields Increase the Activity of Antimicrobials Against Wound Biofilm Pathogens
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Effect of intensive lipid-lowering therapies on cholinesterase activity in patients with coronary artery disease
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Effect of probiotic bacteria on antiradical activity of peptides isolated from dry-cured loins
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Synthesis of sulfanyl porphyrazines with bulky peripheral substituents – Evaluation of their photochemical properties and biological activity
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In vitro photodynamic activity of lipid vesicles with zinc phthalocyanine derivative against Enterococcus faecalis
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Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors
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Spectroelectrochemical analysis of TiO 2 electronic states – Implications for the photocatalytic activity of anatase and rutile
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Physical activity, life satisfaction and adjustment to illness in women after treatment of breast cancer
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A response to “Cardiovascular disease and obstructive sleep apnea: an underappreciated role for increased platelet activity?”
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Characterization of the Three New Kayviruses and Their Lytic Activity Against Multidrug-Resistant Staphylococcus aureus
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Hyperventilation alters arterial baroreflex control of heart rate and muscle sympathetic nerve activity
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The influence of fresh cabbage and sauerkraut juices on the activity of protective enzymes in human cell lines
PublikacjaMechanizmami przeciwrakotwórczego działania związków zawartych w kapuście jest m.in. metaboliczna aktywacja enzymów II fazy detoksykacji, indukcja enzymów naprawczych DNA oraz aktywnośc przeciwutleniająca. Do enzymów II fazy odtruwania należą m.in. S-transferazy glutationowe (GST) oraz oksydoreduktaza chinonowa NQO1 zwana też DT-diaforazą. GST katalizują reakcję sprzęgania glutationu z wieloma różnymi typami ksenobiotyków, ułatwiając...
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Lobularia libyca: Phytochemical Profiling, Antioxidant and Antimicrobial Activity Using In Vitro and In Silico Studies
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An In Vitro Antimicrobial, Anticancer and Antioxidant Activity of N–[(2–Arylmethylthio)phenylsulfonyl]cinnamamide Derivatives
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Effect of GO-Fe3O4 and rotating magnetic field on cellular metabolic activity of mammalian cells
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The covalent and non-covalent conjugation of graphene oxide with hydroxycamptothecin in hyperthermia for its anticancer activity
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Air temperature trends at Mount Śnieżka (Polish Sudetes) and solar activity, 1881–2012
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