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Wyniki wyszukiwania dla: CELL CYCLE, CELL PROTEOME, DIAMOND NANOFILM, EXTRACELLULAR MATRIX, INVASION, LIVER CANCER
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Polyamidoamine Dendrimers Decorated Multifunctional Polydopamine Nanoparticles for Targeted Chemo- and Photothermal Therapy of Liver Cancer Model
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2014 POSTER Serum proteome mass spectrometry analyses for identification of novel diagnostic biomarkers in breast cancer patients
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Partial-Body Irradiation in Patients with Prostate Cancer Treated with IMRT Has Little Effect on the Composition of Serum Proteome
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Cancer immune escape: the role of antigen presentation machinery
PublikacjaThe mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...
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Electrochemical oxidation of sulphamerazine at boron-doped diamond electrodes: Influence of boron concentration
PublikacjaThe boron-doped diamond (BDD) electrodes with different boron concentrations have been tested as electrode material for sulphamerazine (SRM) oxidation in water solution. An investigation of the electrode morphology and molecular structure was carried out using high resolution scanning electron microscopy (SEM) and Raman spectroscopy. Electrochemical results showed clearly that the kinetics and efficiency of SRM oxidation were dependent...
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Life cycle theories of savings and consumption
PublikacjaLife cycle theories of savings and consumption are the economics theories explaining the changes in saving and consumption in the subsequent phases of the human life cycle. There are two main approaches: (1) indicating the dependence of the level of savings and consumption on the average level of income over a long period of human life (life cycle hypothesis; LCH) or (2) on psychological factors, in particular self-control and...
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Synthesis and modification of reduced graphene oxide aerogels for biofuel cell applications
PublikacjaWe have carried out the preparation of reduced graphene oxide aerogels using eco-friendly method that is based on the Hummers method of graphite oxidation without the use of NaNO3 that produces toxic gases. To obtain a porous 3D structure of reduced graphene oxide, we performed the hydrothermal reduction at elevated temperature. We also prepared the rGO aerogel/CNT composite using multiwalled carbon nanotubes as linkers. The rGO...
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Thin Layer Deposition Methods in Solid Oxide Fuel Cell Technology
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Investigations on the immunosuppressive activity of derivatives of mycophenolic acid in immature dendritic cell
PublikacjaThe main activity of mycophenolic acid (MPA) and its analogs is the inhibition of proliferation of T cells. Here, we hypothesized that MPA and its conjugates inhibits also the activity of antigen-presenting cells (APC) including dendritic cells (DCs). We tested the effect of novel amino acid derivatives of MPA and conjugates of MPA with acridines/acridones on DCs by flow cytometry, ELISA and MLR assay. Both acridines/acridone derivatives...
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Assessment of the cell biovolume of phytoplankton widespread in coastal and inland water bodies
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Effect of brefeldin A and castanospermine on resistant cell lines as supplements in anticancer therapy
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Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia
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Molecular action of isoflavone genistein in the human epithelial cell line HaCaT
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Are Radicals Formed During Anion-Exchange Membrane Fuel Cell Operation?
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Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions
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P04.06 Temozolomide influence on global DNA methylation in glioblastoma cell lines
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Effects of Non-Opioid Analgesics on the Cell Membrane of Skin and Gastrointestinal Cancers
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TOLLIP Protein Expression Predicts Unfavorable Outcome in Renal Cell Carcinoma
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Temozolomide and sorafenib as programmed cell death inducers of human glioma cells
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First isolation of polysaccharidic ulvans from the cell walls of freshwater algae
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An Insight into the Stages of Ion Leakage during Red Blood Cell Storage
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“In situ” observations of carbon nanotube generation in CVD cell coupled to spectrometers
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Outdoor I-V measurements of air-cooled silicon solar cell
PublikacjaStosując radiator aluminiowy i przpływ powietrza z obu stron krystalicznego krzemowego ogniwa słonecznego osiągnięto skuteczne odprowadzanie ciepła i schłodzenie do temperatury otoczenia. Nową metodą (przy oświetleniu ogniwa i mniejszym napięciu) wyznaczono rezystancję szeregową i współczynnik nieidealności mierzonej charakterystyki I-V.
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Performance of a fuel cell optimized for in situ X-ray absorption experiments
PublikacjaKomercyjna komórka ogniwa paliwowego typu PEM została zmodyfikowana w celu realizacji pomiaru XAS w warunkach pracy ogniwa. Modyfikacja komórki miała na celu optymalizację jej parametrów pod kątem eksperymentu XAS realizowanego w modzie transmisyjnym i fluorescencyjnym, poprzez minimalizację absorpcji komórki, przy zachowaniu jej parametrów elektrochemicznych. W pracy zostały zaprezentowane szczegóły techniczne komórki a jej efektywność...
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Defect in Mitochondrial NADH-Dehydrogenase Genes in Canine Mast Cell Tumours
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Dabigatran: its protective effect against endothelial cell damage by oxysterol
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C90 PATHOLOGICAL CHARACTERISTICS OF UROTHELIAL CELL CARCINOMA OF THE BLADDER IN YOUNG PATIENTS
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Microbial fuel cell applications for removal of petroleum hydrocarbon pollutants: A review
PublikacjaBioelectrochemical systems (BESs) are considered as the potential approaches to remediate the environments contaminated by hydrocarbons. This review addresses the application of BESs particularly microbial fuel cells (MFCs) in degradation of petroleum hydrocarbons, including BTEXs, from soil, water, wastewater and sediments. Details on reactor design and critical issues are discussed. Aspects on electrodes, redox mediators and...
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Low frequency noise and DLTS as silicon solar cell characterization tools
PublikacjaPraca zawiera wyniki pomiarów DLTS próbek o powierzchni 1 mm2 krzemowych baterii słonecznych wykazujących znaczne niejednorodności wykryte za pomocą metody LBIV (Light Beam Induced Voltage). Wyniki pomiarów charakterystyk stałoprądowych oraz szumowych tych próbek zostały także przedstawione.
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A versatile analog CMOS cell: voltage - buffer /current - conveyor/ multiplier
PublikacjaW pracy przedstawiono koncepcję uniwersalnej komórki analogowej przeznaczonej dla programowalnych układów analogowych (FPAA). Komórka może pełnić funkcję bufora napięciowego, konwjora prądowego lub mnożnika analogowego. Układ przesymulowano w technologii CMOS 2 ćm.
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Performance studies of group parts machining with cell segments of flowline organisation
PublikacjaPrzedstawiono koncepcję modelowania analitycznego struktur gniazdowych systemów wytwarzania określonego spektrum przedmiotów, zorientowanych na spełnienie wymagań oszczędnej produkcji. Wykorzystano przy tym relacje podobieństwa ciągów znakowych, reprezentujących sekwencje dedykowanych do zasobów maszynowych, operacji procesu technologicznego, a których zróżnicowanie oceniano wg kryterium odległości Hamminga oraz Levenshteina. Przeprowadzono...
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Computational Methods for Liver Vessel Segmentation in Medical Imaging: A Review
PublikacjaThe segmentation of liver blood vessels is of major importance as it is essential for formulating diagnoses, planning and delivering treatments, as well as evaluating the results of clinical procedures. Different imaging techniques are available for application in clinical practice, so the segmentation methods should take into account the characteristics of the imaging technique. Based on the literature, this review paper presents...
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JOURNAL OF PROTEOME RESEARCH
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Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells
PublikacjaMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....
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Comparison of Selected Neural Network Models Used for Automatic Liver Tumor Segmentation
PublikacjaAutomatic and accurate segmentation of liver tumors is crucial for the diagnosis and treatment of hepatocellular carcinoma or metastases. However, the task remains challenging due to imprecise boundaries and significant variations in the shape, size, and location of tumors. The present study focuses on tumor segmentation as a more critical aspect from a medical perspective, compared to liver parenchyma segmentation, which is the...
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The use of Yttrium-90 Ibritumomab Tiuxetan ( 90 Y-IT) as a consolidation therapy in high-risk patients with diffuse large B-cell lymphoma ineligible for autologous stem-cell transplantation
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The Effect of Full-Cell Impregnation of Pine Wood (Pinus sylvestris L.) on Changes in Electrical Resistance and on the Accuracy of Moisture Content Measurement Using Resistance Meters
PublikacjaThe impact of the full-cell impregnation of pine wood was investigated with respect to changes in electrical resistance and the accuracy of moisture content measurement. This study compared the resistance of impregnated and untreated pine timber harvested from the northern part of Poland (Pomeranian region). The wood was impregnated by the vacuum-pressure method. The preservative (TANALITH E 3475) and coloring (TANATONE 3950) agents...
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Cytocompatibility of stabilized black phosphorus nanosheets tailored by directly conjugated polymeric micelles for human breast cancer therapy
PublikacjaThe novel procedure of few-layer black phosphorus (FLBP) stabilization and functionalisation was here proposed. The cationic polymer PLL and non-ionic PEG have been involved into encapsulation of FLBP to allow sufficient time for further nanofabrication process and overcome environmental degradation. Two different spacer chemistry was designed to bind polymers to tumor-homing peptides. The efficiency of functionalisation was examined...
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Application of Bladder Acellular Matrix in Urinary Bladder Regeneration: The State of the Art and Future Directions
PublikacjaConstruction of the urinary bladder de novo using tissue engineering technologies is the “holy grail” of reconstructive urology. The search for the ideal biomaterial for urinary bladder reconstruction has been ongoing for decades. One of the most promising biomaterials for this purpose seems to be bladder acellular matrix (BAM). In this review we determine the most important factors, which may affect biological and physical properties...
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Diamond Structures for Tuning of the Finesse Coefficient of Photonic Devices
PublikacjaFinesse coefficient is one of the most important parameters describing the properties of a resonant cavity. In this research, a mathematical investigation of the application of diamond structures in a fiber-optic Fabry–Perot measurement head to assess their impact on the finesse coefficient is proposed. We present modeled transmission functions of cavities utilizing a nitrogen-doped diamond, a boron-doped diamond, nanocrystalline...
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Exergy Losses in the Szewalski Binary Vapor Cycle
PublikacjaIn this publication, we present an energy and exergy analysis of the Szewalski binary vapor cycle based on a model of a supercritical steam power plant. We used energy analysis to conduct a preliminary optimization of the cycle. Exergy loss analysis was employed to perform a comparison of heat-transfer processes, which are essential for hierarchical cycles. The Szewalski binary vapor cycle consists of a steam cycle bottomed with...
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Looking for a minimum exergy destruction in hierarchical cycle
PublikacjaThe paper presents results of energy analysis, complemented with an exergy balance, of hierarchical thermodynamic cycle. Proposed cycle is a binary vapour cycle based on a model of real supercritical steam power plant. Energy analysis is used to preliminary optimization of the cycle and the exergy losses analysis is proposed to perform optimization of heat transfer processes, which are essential for hierarchical cycles. Proposed...
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3D Hierarchical Boron-Doped Diamond-Multilayered Graphene Nanowalls as an Efficient Supercapacitor Electrode
PublikacjaSynthesis of stable hybrid carbon nanostructure for high-performance supercapacitor electrode with long life-cycle for electronic and energy storage devices is a real challenge. Here, we present a one-step synthesis method to produce conductive boron-doped hybrid carbon nanowalls (HCNWs), where sp2-bonded graphene has been integrated with and over a three-dimensional curved wall-like network of sp3-bonded diamond. The spectroscopic...
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Structural and electronic properties of diamond-composed heterostructures
PublikacjaDiamond is a promising material for 21st century electronics due to its high thermal and electronic conductivity, biocompatibility, chemical stability, high wear resistance, and possibility of doping. However, the semiconductor properties of diamond, especially free-standing films, have not been fully explored. Nor have their integration with polymers and fragile materials and their applications as electronic components. In this...
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RAMAN DIAGNOSTICS OF CVD DIAMOND GROWTH
PublikacjaDevelopment of Raman spectroscopic system for diagnostics of growth of diamond and BDD (Boron- Doped-Diamond) thin films during μPA CVD (Microwave Plasma Assisted Chemical Vapour Deposition) process is described. Raman studies of such films were carried out as in-situ monitoring of film deposition as ex-situ measurements conducted for a sample outside the reaction vessel after manufacturing process. Modular system for the in-situ...
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Plasma free amino acid profiling as metabolomic diagnostic and prognostic biomarker in paediatric cancer patients: a follow‑up study
PublikacjaAmino acids (AAs) play a crucial role in cancer cell metabolism. Levels of 22 plasma AAs at the time of diagnosis and after treatment were established among 39 pediatric cancer patients and 33 healthy children. Glutamic acid levels decreased and tryptophan levels increased during treatment. Cancer patients presented significantly lower levels of glutamine and leucine post-treatment while levels of 12 other AAs were higher comparing...
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Diamond-based protective layer for optical biosensors
PublikacjaOptical biosensors have become a powerful alternative to the conventional ways of measurement owing to their great properties, such as high sensitivity, high dynamic range, cost effectiveness and small size. Choice of an optical biosensor's materials is an important factor and impacts the quality of the obtained spectra. Examined biological objects are placed on a cover layer which may react with samples in a chemical, biological...
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Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer
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OC-0265: Whole body response to radiation in head and neck and prostate cancer patient; the serum proteome comparative analysis
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Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27)
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