Filtry
wszystkich: 1492
-
Katalog
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: PROTEIN GENE EXPRESSION
-
Journal of Genetic Syndromes & Gene Therapy
Czasopisma -
Recent Advances in DNA and Gene Sequences
Czasopisma -
The hydration properties of protein stabilizer, trimethylamine-N-oxide in aqueous solutions of N-methylacetamide – The volumetric and compressibility studies between 288.15 and 308.15 K
PublikacjaApparent molar volumes and apparent molar isentropic compressions of the protein stabilizer, trimethylamine-N-oxide (TMAO) were determined from the densities and speed of sound measured at T = (288.15, 298.15 and 308.15) K in aqueous solutions of N-methylacetamide (NMA) at four different concentrations (2, 4, 6 and 8 mol/kg). The concentration dependencies of the calculated quantities extrapolated to the infinite dilution lead...
-
Chiral Pyrazolo[4,3-e][1,2,4]triazine Sulfonamides—Their Biological Activity, Lipophilicity, Protein Affinity, and Metabolic Transformations
PublikacjaReferring to our previous laboratory results related to the tyrosinase and urease inhibition by pyrazolo[4,3-e][1,2,4]triazine sulfonamides, we examined here in silico the mechanism of action at the molecular level of the investigated pyrazolotriazine sulfonamides by the molecular docking method. The studied compounds being evaluated for their cytotoxic effect against cancer cell lines (MCF-7, K-562) and for recombinant Abl and...
-
First recurrent large genomic rearrangement in the BRCA1 gene found in Poland
Publikacja -
Statistical Integration of p-values for Enhancing Discovery of Radiotoxicity Gene Signatures
Publikacja -
Iron overload and HFE gene mutations in Polish patients with liver cirrhosis
Publikacja -
K-ras gene mutation as an early prognostic marker of colon cancer
Publikacja -
Vitamin D Metabolism Gene Polymorphisms and Their Associated Disorders: A Literature Review
Publikacja -
Clinical presentation of Y189C mutation of the NOTCH3 gene in the Polish family with CADASIL
Publikacja -
Adverse Childhood Experiences and Methylation of the FKBP5 Gene in Patients with Psychotic Disorders
Publikacja -
HPV16 E6 Gene Transcripts in Primary Type II Endometrial Carcinomas
Publikacja -
Role of the disulfide bond in stabilizing and folding of the fimbrial protein DraE from uropathogenic Escherichia coli
PublikacjaDr fimbriae are homopolymeric adhesive organelles of uropathogenic Escherichia coli composed of DraE subunits, responsible for the attachment to host cells. These structures are characterized by enormously high stability resulting from the structural properties of an Ig-like fold of DraE. One feature of DraE and other fimbrial subunits that makes them peculiar among Ig-like domain-containing proteins is a conserved disulfide bond...
-
Gene Alogia magister
Osoby -
A bifunctional chimeric protein consisting of MutS and beta-galactosidase
Publikacja -
The protein folding problem: global optimization of force fields
Publikacja -
Lipid-protein interactions in membranes: a molecular modelling study
Publikacja -
Effect of increased protein intake on the risk of female infertility
Publikacja -
Copper containing protein sites - structure, properties and models
PublikacjaEnzymy organizmów żywych katalizują wiele reakcji stosowanych w przemyśle chemicznym. Przykładem potencjalnego zastosowania enzymu w produkcji jest synteza L-Dopy przy udziale tyrozynazy. Ze względu na możliwe praktyczne zastosowanie w katalizie, otrzymano i opisano wiele prostych modeli miejsc aktywnych enzymów. W artykule opisano niektóre modele białek zawierających miedź.
-
A bifunctional chimeric protein consisting of MutS and beta-galactoside
PublikacjaPraca pokazuje konstrukcję DNA plazmidowego kodującego bifunkcjonalne białko chimeryczne złożone z MutS Thermus thermophilus i beta-galaktozydazy E.coli, optymalizację jego ekspresji i oczyszczania. Białko to testowano w metodzie wykrywania mutacji punktowych, wykorzystując kolorymetryczne mierzenie aktywności domeny reporterowej beta galaktozydazy.
-
Electrosynthesis of potato starch–whey protein isolate complexes
Publikacja -
The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana
Publikacja -
The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana
Publikacja -
Role of Oligosaccharide Chain Polarity in Protein–Glycosaminoglycan Interactions
Publikacja -
Extracellular matrix metalloproteinase inducer (EMMPRIN) expression correlates positively with active angiogenesis and negatively with basic fibroblast growth factor expression in epithelial ovarian cancer
Publikacja -
CD73 Expression as a Potential Marker of Good Prognosis in Breast Carcinoma
Publikacja -
Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Publikacja -
Nicotinamide phosphoribosyltransferase expression in thyroid glands of patients with Graves' disease
Publikacja -
Comprehensive analysis of microRNA expression profile in malignant glioma tissues
Publikacja -
A novel cold-active β-D-galactosidase with transglycosylation activity from the Antarctic Arthrobacter sp. 32cB - gene cloning, purification and characterization
PublikacjaA gene encoding a novel β-D-galactosidase from the psychrotolerant Antarctic bacterium Arthrobacter sp. 32cB was isolated, cloned and expressed in Escherichia coli. The active form of recombinant β-D-galactosidase consists of two subunits with a combined molecular weight of approximately 257 kDa. The enzyme's maximum activity towards o-nitrophenyl-β-D-galactopyranoside was determined as occurring at 28 °C and pH 8.0. However, it...
-
Long-range, water-mediated interaction between a moderately active antifreeze protein molecule and the surface of ice
PublikacjaUsing molecular dynamics simulations, we show that a molecule of moderately active antifreeze protein (type III AFP, QAE HPLC-12 isoform) is able to interact with ice in an indirect manner. This interaction occurs between the ice binding site (IBS) of the AFP III molecule and the surface of ice, and it is mediated by liquid water which separates these surfaces. As a result, the AFP III molecule positions itself at a specific orientation...
-
Monocyte Chemoattractant Protein-Induced Protein 1 (MCPIP1) Enhances Angiogenic and Cardiomyogenic Potential of Murine Bone Marrow-Derived Mesenchymal Stem Cells
Publikacja -
Optical method supported by machine learning for dynamics of C‐reactive protein concentrations changes detection in biological matrix samples
PublikacjaIn this article we present the novel spectroscopy method supported with machine learning for real-time detection of infectious agents in wastewater. In the case of infectious diseases, wastewater monitoring can be used to detect the presence of inflammation biomarkers, such as the proposed C-reactive protein, for monitoring inflammatory conditions and mass screening during epidemics for early detection in communities of concern,...
-
Prognostic Significance of TOP2A Gene Dosage in HER-2-Negative Breast Cancer
Publikacja -
Germline mutations in theCHEK2 kinase gene are associated with an increased risk of bladder cancer
Publikacja -
Gene set enrichment for reproducible science: comparison of CERNO and eight other algorithms
Publikacja -
Proteins Structure Models in the Evaluation of Novel Variant (C.472_477del) in the MOCS2 Gene
Publikacja -
Association of ENAM gene single nucleotide polymorphisms with dental caries in Polish children
Publikacja -
Research Trends of Vitamin D Metabolism Gene Polymorphisms Based on a Bibliometric Investigation
Publikacja -
The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease
Publikacja -
Relationship between polymorphism in the CRH gene and the traits of body conformation of Salers cows
Publikacja -
Cloning of the thermostable alpha-amylase gene from Pyrococcus woesei in Escherichia coli.
PublikacjaGen kodujący alfa-amylazę z Pyrococcus woesei klonowano do plazmidów pET21d(+)lub pYTB2, którymi transformowano komórki Escherichia coli. Otrzymana rekombinantowa alfa amylaza wykazuje maksymalną aktywność przy pH 5.6 w temperaturze 95 stC i przejawia około 24 % początkowej aktywności nawet po 2 godz. inkubacji w 120 stC. Duża termostabilność otrzymanego preparatu świadczy o jego przydatności do enzymatycznego upłynniania skrobi.
-
Software tools for identification, visualization and analysis of protein tunnels and channels
Publikacja -
C-reactive Protein as a Diagnostic and Prognostic Factor of Endometrial Cancer
Publikacja -
Assessment of chemical‐crosslink‐assisted protein structure modeling in CASP13
Publikacja -
C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
Publikacja -
Nutritional value, protein and peptide composition of edible cricket powders
Publikacja -
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Publikacja -
Structural Analysis of a Peptide Fragment of Transmembrane Transporter Protein Bilitranslocase
Publikacja -
Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70
PublikacjaThe J-domain protein Zuotin is a multi-domain eukaryotic Hsp70 co-chaperone. Though it is primarily ribosome-associated, positioned at the exit of the 60S subunit tunnel where it promotes folding of nascent polypeptide chains, Zuotin also has off-ribosome functions. Domains of Zuotin needed for 60S association and interaction with Hsp70 are conserved in eukaryotes. However, whether the 4-helix bundle (4HB) domain is conserved remains...