wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: CANCER
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Infectious Agents and Cancer
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Journal of Gastric Cancer
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Cancer Management and Research
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Journal of Pancreatic Cancer
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Clinical Skin Cancer
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Clinical Cancer Drugs
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Cancer and Chemotherapy Reviews
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Gastric and Breast Cancer
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npj Breast Cancer
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Cancer Research and Clinic
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Lung Cancer Management
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Cancer Treatment and Research
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INTEGRATIVE CANCER THERAPIES
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Lung Cancer International
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Precision Cancer Medicine
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Blood Cancer Discovery
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Journal of Breast Cancer
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MOLECULAR CANCER RESEARCH
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JNCI Cancer Spectrum
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Radiology-Imaging Cancer
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JOURNAL OF CANCER EDUCATION
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NATURE REVIEWS CANCER
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Journal of Cancer Prevention
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Revisiones en Cancer
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ANTI-CANCER DRUGS
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Cancer Drug Resistance
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Annals of Pancreatic Cancer
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MOLECULAR CANCER THERAPEUTICS
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PEDIATRIC BLOOD & CANCER
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SEMINARS IN CANCER BIOLOGY
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SUPPORTIVE CARE IN CANCER
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Cancer immune escape: the role of antigen presentation machinery
PublikacjaThe mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...
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Cancer-selective, single agent chemoradiosensitising gold nanoparticles
PublikacjaTwo nanometre gold nanoparticles (AuNPs), bearing sugar moieties and/or thiol-polyethylene glycol-amine (PEG-amine), were synthesised and evaluated for their in vitro toxicity and ability to radiosensitise cells with 220 kV and 6 MV X-rays, using four cell lines representing normal and cancerous skin and breast tissues. Acute 3 h exposure of cells to AuNPs, bearing PEG-amine only or a 50:50 ratio of alpha-galactose derivative and...
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Role of the Synergistic Interactions of Environmental Pollutants in the Development of Cancer
PublikacjaThere is a growing awareness that the large number of environmental pollutants we are exposed to on a daily basis are causing major health problems. Compared to traditional studies that focus on individual pollutants, there are relatively few studies on how pollutants mixtures interact. Several studies have reported a relationship between environmental pollutants and the development of cancer, even when pollutant levels are below...
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Towards Cancer Patients Classification Using Liquid Biopsy
PublikacjaLiquid biopsy is a useful, minimally invasive diagnostic and monitoring tool for cancer disease. Yet, developing accurate methods, given the potentially large number of input features, and usually small datasets size remains very challenging. Recently, a novel feature parameterization based on the RNA-sequenced platelet data which uses the biological knowledge from the Kyoto Encyclopedia of Genes and Genomes, combined with a classifier...
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Gene copy numbers of HER family in breast cancer
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Circadian Gene Polymorphisms Associated with Breast Cancer Susceptibility
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Neural network breast cancer relapse time prognosis
PublikacjaPrzedstawiono architekturę i wyniki testowania sztucznej sieci neuronowej w prognozowaniu czasu nawrotu choroby u kobiet chorych na raka piersi. Sieć neuronowa uczona była na danych zgromadzonych przez 20 lat. Dane opisują grupę 439 pacjentów za pomocą 40 parametrów. Spośród tych parametrów wybrano 6 najistotniejszych: liczbę przerzutowych węzłów chłonnych, wielkość guza, wiek, skalę według Blooma oraz stan receptorów estrogenowych...
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Coping strategies and sexual satisfaction in bladder cancer males
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High-grade serous ovarian cancer: the clone wars
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The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies
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Single nucleotide polymorphisms associated with papillary thyroid cancer
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Probiotic Bacteria: A Promising Tool in Cancer Prevention and Therapy
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Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface
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Novel Inhibitor-Based Therapies for Thyroid Cancer—An Update
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Inhibitors of angiogenesis in cancer therapy – synthesis and biological activity
PublikacjaAngiogenesis is the process of formation of new capillaries from preexisting blood vessels. Angiogenesis is involved in normal physiological processes, and plays an important role in tumor invasion and development of metastases. Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis. VEGF is a mitogen for vascular endothelial cells and stimulates their proliferation. By inhibiting the biological activity of...
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Cancer stem cells in drug resistance and drug screening: can we exploit the cancer stem cell paradigm in search for new antitumor agents?
PublikacjaPraca przedstawia przegląd literatury dotyczącej hipotezy komórek pierwotnych nowotworu, w szczególności w ich oporności na istniejące terapie. Dyskutowane jest także zagadnienie możliwości wykorzystania wiedzy o tych komórkach do konstrukcji nowych testów do badań przesiewowych in vitro w celu poszukiwania nowych leków przeciwnowotworowych.
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Survival time prognosis under a Markov model of cancer development
PublikacjaIn this study we look at a breast cancer data set of women from Pomerania region collected in year 1987-1992 in the Medical University of Gdańsk. We analyze the clinical risk factors in conjunction with Markov model of cancer development. We evaluate Artificial Neural Network (ANN) survival time prediction via a simulation study.
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Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
PublikacjaPurpose: Surgical resection of hepatocellular carcinoma can be associated with recurrence resulting from the degeneration of residual volume of the liver. The objective was to assess the possibility of using a biocompatible nanofilm, made of a colloid of diamond nanoparticles (nfND), to fill the side after tumour resection and optimize its contact with proliferating liver cells, minimizing their cancerous transformation. Methods:...
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Folate/homocysteine metabolism and lung cancer risk among smokers
PublikacjaBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
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Serum mass profile signature as a biomarker of early lung cancer
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An inherited NBN mutation is associated with poor prognosis prostate cancer
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The presence of prostate cancer at biopsy is predicted by a number of genetic variants
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(CA)n Microsatellite polymorphism of ERBB-1 in breast cancer
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A deletion in CHEK2 of 5,395 bp predisposes to breast cancer in Poland
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XPD Common Variants and their Association with Melanoma and Breast Cancer Risk
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Cancer Familial Aggregation (CFA) and G446A polymorphism in ARLTS1 gene
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Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways
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Microbiota-derived metabolites in colorectal cancer patients in preoperative period
PublikacjaShort-chain fat-ty acids (SCFAs) are microbial derived metabo-lites, which have multiple beneficial properties. The amount of SCFAs depends on several fac-tors, such as age, diet (mainly intake of dietary fiber), and overall health condition. The normal proportion between SCFAs is 3:1:1 for acetate, proprionate and butyrate, respectively. In col-orectal cancer (CRC) patients, microbiota alter-ations have been shown. Consequently,...
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Common variants of xeroderma pigmentosum genes and prostate cancer risk
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Sulforaphane inhibits growth of phenotypically different breast cancer cells
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The ICTBioMed NCIP Hub: Cancer research in a science gateway consortium
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Notch signalling pathway as an oncogenic factor involved in cancer development
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The role of Snail1 transcription factor in colorectal cancer progression and metastasis
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Nuclear quantum effects in a HIV/cancer inhibitor: The case of ellipticine
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Pemphigus foliaceus in a patient with skin cancer with metastases to lymph nodes
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VEGF – targeted therapy for the treatment of cervical cancer – literature review
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Analysis of 5-Methylcytosine in DNA of Breast and Colon Cancer Tissues
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C-reactive Protein as a Diagnostic and Prognostic Factor of Endometrial Cancer
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The effects of RNA editing in cancer tissue at different stages in carcinogenesis
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Bladder cancer detection using a peptide substrate of the 20S proteasome
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Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis
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C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
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Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
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Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
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Biological Effects of Cold Atmospheric Pressure Plasma on Skin Cancer
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The p53-mediated cytotoxicity of photodynamic therapy of cancer: Recent advances
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Clinical Relevance of Circulating Tumor Cells in Prostate Cancer Management
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The Role of miRNA-7 in the Biology of Cancer and Modulation of Drug Resistance
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New Unsymmetrical Bisacridine Derivatives Noncovalently Attached to Quaternary Quantum Dots Improve Cancer Therapy by Enhancing Cytotoxicity toward Cancer Cells and Protecting Normal Cells
PublikacjaThe use of nanoparticles for the controlled drug delivery to cells has emerged as a good alternative to traditional systemic delivery. Quantum dots (QDs) offer potentially invaluable societal benefits such as drug targeting and in vivo biomedical imaging. In contrast, QDs may also pose risks to human health and the environment under certain conditions. Here, we demonstrated that unique combination of nanocrystals core components...
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Stage I non-small-cell lung cancer: long-term results of lobectomy versus sublobar resection from the Polish National Lung Cancer Registry†
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Comparison of peptide cancer signatures identified by mass spectrometry in serum of patients with head and neck, lung and colorectal cancers: Association with tumor progression
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Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract
PublikacjaThe present article includes data on the possible selective cytotoxic effect of extract of Ribes nigrum L. growing at high Armenian landscape. For this purpose, different non-cancer (microglial BV-2 wild type (Wt), acyl-CoA oxidase 1 (ACOX1) deficient (Acox1-/-) and cancer (human colon adenocarcinoma HT29 and human breast cancer MCF7) cell lines were applied. R. nigrum leaf ethanol extract showed a growth inhibition effect towards...
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Assestment of the anti-cancer activity of the copper complexes with imidazole and pivalato ligands
PublikacjaDespite the development of science and technology progress so far there have not been found effective drugs for cancer. Many coordination compounds were investigated due to their antitumor potential. The most known cis-diamminedichloroplatinum(II) is used as anti-cancer therapeutic agent. The copper complexes are the coordination compounds possessing anti-tumour properties. Their capability to kill cancer cells is mainly linked...
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Predictions of cervical cancer identification by photonic method combined with machine learning
PublikacjaCervical cancer is one of the most commonly appearing cancers, which early diagnosis is of greatest importance. Unfortunately, many diagnoses are based on subjective opinions of doctors—to date, there is no general measurement method with a calibrated standard. The problem can be solved with the measurement system being a fusion of an optoelectronic sensor and machine learning algorithm to provide reliable assistance for doctors...
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cDNA sequencing improves the detection of P53 missense mutations in colorectal cancer
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Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines
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MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
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Severe oxidatively damaged DNA after cisplatin treatment of cancer patients
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RAGE as a Novel Biomarker for Prostate Cancer: A Systematic Review and Meta-Analysis
PublikacjaThe receptor for advanced glycation end-products (RAGE) has been implicated in driving prostate cancer (PCa) growth, aggression, and metastasis through the fueling of chronic inflammation in the tumor microenvironment. This systematic review and meta-analysis summarizes and analyzes the current clinical and preclinical data to provide insight into the relationships among RAGE levels and PCa, cancer grade, and molecular effects....
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The rs1447295 and DG8S737 markers on chromosome 8q24 and cancer risk in the Polish population
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublikacjaDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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Insights into oral microbiome and colorectal cancer – on the way of searching new perspectives
PublikacjaMicrobiome is a keystone polymicrobial community that coexist with human body in a beneficial relationship. These microorganisms enable the human body to maintain homeostasis and take part in mechanisms of defense against infection and in the absorption of nutrients. Even though microbiome is involved in physiologic processes that are beneficial to host health, it may also cause serious detrimental issues. Additionally, it has been...
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Cadmium, arsenic, selenium and iron– Implications for tumor progression in breast cancer
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Metachronous adenocarcinoma in a gastric tube after radical surgery for oesophageal cancer
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A common nonsense mutation of the BLM gene and prostate cancer risk and survival
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Breast Cancer Heterogeneity Investigation: Multiple k-Means Clustering Approach
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Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer
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Erratum to: Sulforaphane inhibits growth of phenotypically different breast cancer cells
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The Influence of Antitumor Unsymmetrical Bisacridines on 3D Cancer Spheroids Growth and Viability
PublikacjaThe culture of 3D spheroids is a promising tool in drug development and testing. Recently, we synthesized a new group of compounds, unsymmetrical bisacridines (UAs), which exhibit high cytotoxicity against various human cell lines and antitumor potency against several xenografts. Here, we describe the ability of four UAs—C-2028, C-2041, C-2045, and C-2053—to influence the growth of HCT116 and H460 spheres and the viability of HCT116...