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Wyniki wyszukiwania dla: controlled drug delivery
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Corporate Governance 2022
Kursy OnlineThe course deals with a broadened view of Corporate Governance since: a) It explores the dynamic relationships among the ownership structures, the governance structures, and the strategies that firms adopt. b) It relates to a variety of firms, including the specific case of family controlled companies. c) It is declined into two complementary perspectives: the managerial perspective, and the historical perspective based on international...
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Sensorless Multiscalar Control of Five-Phase Induction Machine with Inverter Output Filter
PublikacjaThe paper presents a complete solution for speed sensorless control system for five-phase induction motor with voltage inverter, LC filter and nonlinear control of combined fundamental and third harmonic flux distribution. The control principle, also known as multiscalar control, nonlinear control or natural variables control, is based on a use of properly selected scalar variables in control feedback to linearize controlled system....
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The Creation of an Antimicrobial Coating on Contact Lenses by The Use of Nanocopper
PublikacjaThe aim of the research was to creation an antimicrobial coating on contact lens and examine the ability of copper nanoparticles to decrease microbial adhesion and prevent the growth of bacteria. The creation was based on the immersion method in solution with dispersed nanoparticles of copper at concentration 200 pm. There were evaluated follows factors: time of immersion and base to dispersed nanoparticles. Three solutions: ethyl...
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THE INFLUENCE OF THE URBAN DESIGN ON THE AIR EXCHANGE IN CITIES. SELECTED PROBLEMS IN POLISH REALITY
PublikacjaThe progress of the architecture and urbanism raises problems requiring interdisciplinary research conducted with the use of advanced experimental techniques and computer simulation. The fields of this research include aerodynamics, especially in intensively developed area of Environmental Wind Engineering (EWE). Aerodynamic phenomena occurring around buildings have a significant impact on the quality of the climate in the cities....
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Analysis of wave propagation in a bolted steel joint
PublikacjaThe paper presents results of numerical and experimental investigations of elastic wave propagation in a bolted single-lap joint. The research was carried out for both symmetric and antisymmetric Lamb wave modes. In experimental studies the PZT transducers were used to excite and register wave propagation signals. The controlled value of the torque during measurements was ensured by the use of high precision torque wrenches. Numerical...
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The Use of Free Adjustment and Msplit-Estimation for Determination of the Vertical Displacements in Unstable Reference System
PublikacjaThe problem of the determining of the displacements of engineering objects and their surroundings is the current and important issue in the field of engineering geodesy. Most control measurements are made in relation to reference points (stable points). On the other hand, sometimes it happens that it is not possible perform the measurements with reference to the stable points or identification of stable points is difficult. Therefore,...
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Materiał węglowy ptrzymany na bazie karbonizowanego chitozanu domieszkowanego platyną = CARBON MATERIAL RECEIVED THROUGH CARBONIZATION OF CHITOSAN DOPED WITH PLATINUM
PublikacjaThe aim of this work was to investigate the impact of porous carbons with high nitrogen content onthe platinum catalyst performance properties. The system may be applied as well as cathodic catalyst for oxygenreduction in microbial fuel cells.We report a simple route for preparation of dispersed Platinum on the carbon support. Chitosan powder wasprotonated using aqueous solution of organic acid. The water from the pores was removed...
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Eye-Gaze Tracking-Based Telepresence System for Videoconferencing
PublikacjaAn approach to the teleimmersive videoconferencing system enhanced by the pan-tilt-zoom (PTZ) camera, controlled by the eye-gaze tracking system, is presented in this paper. An overview of the existing telepresence systems, especially dedicated to videoconferencing is included. The presented approach is based on the CyberEye eye-gaze tracking system engineered at the Multimedia Systems Department (MSD) of Gdańsk University of Technology...
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Using an IEEE1149.1 Test Bus for Fault Diagnosis of Analog Parts of Electronic Embedded Systems
PublikacjaThe new solution of a BIST called the JTAG BIST for self-testing of analog parts of electronic embedded systems is presented in the paper. The JTAG BIST consists of the BCT8244A and SCANSTA476 integrated circuits of Texas Instruments controlled via the IEEE 1149.1 bus. The BCT8244A is a scan test device with octal buffers, and the SCANSTA476 is a 12-bit ADC with 8 analog input channels. Self-testing approach is based on the fault...
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SAMPLE-AND-HOLDING METHOD FOR GAS SENSING APPLIED FOR RESISTANCE GAS SENSORS
PublikacjaThe DC resistance of a Taguchi gas sensor is influenced by the ambient gas. To improve the selectivity and sensitivity of a sensor the fluctuation enhanced sensing (FES) was used. The paper proposes a novel methodology of utilizing FES technique that sample composition of an ambient atmosphere and hold it for further processing (sample-and-holding technique). The method uses the heated gas sensor to sample an ambient atmosphere...
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The distributed model predictive controller for the nuclear power plant turbo-generator set
PublikacjaTypically there are two main control loops with PI controllers operating at each turbo-generator set. In this paper a distributed model predictive controller DMPC, with local QDMC controllers for the turbine generator, is proposed instead of a typical PI controllers. The local QDMC controllers utilize step-response models for the controlled system components. These models parameters are determined based on the proposed black-box...
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Robustness Analysis of a Distributed MPC Control System of a Turbo-Generator Set of a Nuclear Plant – Disturbance Issues
PublikacjaTypically, there are two main control loops with PI controllers operating at each turbo-generator set. In this paper, a distributed model predictive controller with local quadratic model predictive controllers for the turbine generator is proposed instead of a set of classical PI controllers. The local quadratic predictive controllers utilize step-response models for the controlled system components. The parameters of these models...
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Analiza wielokryterialna wariantów systemu zaopatrzenia w wodę zespołu padów
PublikacjaJednym z istotnych problemów decyzyjnych na etapie potencjalnej eksploatacji gazu z formacji łupkowych jest wybór sposobu zaopatrzenia w wodę kopalni gazu łupkowego. Z uwagi na duże zapotrzebowanie na wodę do procesu szczelinowania kolejno przekazywanych do eksploatacji odwiertów wydobywczych, należy poszukiwać systemu zaopatrzenia w wodę, który zagwarantuje wymaganą jej ilość, a jednocześnie nie będzie zbyt dużym obciążeniem dla...
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Wpływ ścieków przemysłowych na energochłonność i efektywność procesów technologicznych w komunalnej oczyszczalni ścieków
PublikacjaW artykule skupiono się na przedstawieniu wpływu jakości i ilości ścieków przemysłowych wprowadzanych do sieci kanalizacyjnej PEWIK GDYNIA Sp. z o. o. na stabilność procesów technologicznych. Określono również wpływ ścieków przemysłowych na energochłonność i efektywność oraz na wzrost kosztów oczyszczania ścieków komunalnych w Grupowej Oczyszczalni Ścieków „Dębogórze” w latach 2012-2015.
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Postawy osób starszych wobec tradycyjnych i innowacyjnych kanałów dystrybucji usług finansowych
PublikacjaRosnący udział osób starszych w strukturze populacji stawia nowe wyzwania przed przedsiębiorstwami oferującymi produkty do nich skierowane. Przykładem takich produktów są usługi finansowe. Przedmiotem niniejszego tekstu są usługi ubezpieczeniowe i bankowe oferowane osobom starszym z wykorzystaniem tradycyjnych i nowoczesnych kanałów dystrybucji. Na podstawie przeglądu literatury sformułowano dwie hipotezy badawcze: H1: Cechy społeczno-demograficzne...
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Computational methods for calculation of binding free energy for ligand-receptor complexes
PublikacjaAccurate description of the molecular complexes energetic influence is required for understanding of many biological functions carried out by proteins. Therefore, estimation of binding free energy for ligand-receptor complexes is of highest importance for structure-based ligand design and drug discovery approaches.Experimental methods of determination of difference in Gibbs'es free energy have many limitations. Thus, computational...
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Radiosensitization of DNA in presence of Pt(II)-based compounds
PublikacjaX-ray irradiation of plasmid DNA in presence of platinum (II)-based compounds was carried out in order to assess the radiosensitization capabilities of these drugs. In present investigations pBR322 plasmid DNA was used to monitor the effectiveness of chosen compounds in inducing strand breaks. Samples were incubated in the presence of potential radiosensitisers: platinum (II) bromide and cis-diamminedibromoplatinum (II). The results...
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Synthesis and biological evaluation of novel analogues of batracylin with synthetic amino acids and adenosine: an unexpected effect on centromere segregation in tumor cells through a dual inhibition of topoisomerase IIa and Aurora B
PublikacjaIn the search for new anticancer agents we designed and synthesized batracylin derivatives with linking synthetic amino acid side chains of different lengths and adenosine. Unexpectedly, we have found that in water and the culture media adenosine–amino acid–BAT conjugates form supramolecular structures and this prevents these compounds from entering cells. Consequently, these compounds exerted no biological activity when tested...
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Recent progress in the development of steroid sulfatase inhibitors – examples of the novel and most promising compounds from the last decade
PublikacjaThe purpose of this review article is to provide an overview of recent achievements in the synthesis of novel steroid sulfatase (STS) inhibitors. STS is a crucial enzyme in the biosynthesis of active hormones (including estrogens and androgens) and, therefore, represents an extremely attractive molecular target for the development of hormone-dependent cancer therapies. The inhibition of STS may effectively reduce the availability...
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Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics – synthesis and properties
PublikacjaGlucosamine-6-phosphate synthase (GlcN-6-P synthase) is known as a promising target for antimicrobial agents and antidiabetics. Several compounds of natural or synthetic origin have been identified as inhibitors of this enzyme. This set comprises highly selective L-glutamine, amino sugar phosphate or transition state intermediate cis-enolamine analogues. Relatively low antimicrobial activity of these inhibitors, poorly penetrating...