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Wyniki wyszukiwania dla: CYGARA
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Zaawansowane rozwiązania projektowe aplikacji typu Rich Internet Application
PublikacjaRich Internet Application (RIA) jest modelem aplikacji internetowych zyskującym w ostatnim czasie coraz większą popularność. Jednym ze sposobów jego realizacji jest paradygmat AJAX. Stosowane w nowatorski sposób, istniejące od wielu lat technologie pozwalają osiągnąć niespotykane dotąd możliwości. Wieloletnie doświadczenia programistów powodują jednak, że w aplikacjach tego typu stosuje się często rozwiązania projektowe przeznaczone...
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Membrane cleaning and pretreatments in membrane distillation – a review
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Improving platelet‐RNA‐based diagnostics: a comparative analysis of machine learning models for cancer detection and multiclass classification
PublikacjaLiquid biopsy demonstrates excellent potential in patient management by providing a minimally invasive and cost-effective approach to detecting and monitoring cancer, even at its early stages. Due to the complexity of liquid biopsy data, machine-learning techniques are increasingly gaining attention in sample analysis, especially for multidimensional data such as RNA expression profiles. Yet, there is no agreement in the community...
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Novel Tools for Comprehensive Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants
PublikacjaFamilial hypercholesterolemia (FH) is an autosomal-dominant disorder caused mainly by substitutions in the low-density lipoprotein receptor (LDLR) gene, leading to an increased risk of premature cardiovascular diseases. Tremendous advances in sequencing techniques have resulted in the discovery of more than 3000 variants of the LDLR gene, but not all of them are clinically relevant. Therefore, functional studies of selected variants...
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A novel hierarchically-porous diamondized polyacrylonitrile sponge-like electrodes for acetaminophen electrochemical detection
PublikacjaA novel composite electrode material consisting of tangled fibrous polyacrylonitrile-based hierarchically-struc- tured nanocomposites has been produced by wet-spinning, carbonized and decorated with a carbon nano- architecture by microwave plasma-enhanced chemical vapor deposition and investigated as a metal-free electrode for the enhanced electrochemical detection of acetaminophen. Surprisingly, the hierarchical fiber ar- chitecture...
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Creating new voices using normalizing flows
PublikacjaCreating realistic and natural-sounding synthetic speech remains a big challenge for voice identities unseen during training. As there is growing interest in synthesizing voices of new speakers, here we investigate the ability of normalizing flows in text-to-speech (TTS) and voice conversion (VC) modes to extrapolate from speakers observed during training to create unseen speaker identities. Firstly, we create an approach for TTS...
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Decision making process using deep learning
PublikacjaEndüstri 4.0, dördüncü endüstri devrimi veya Endüstriyel Nesnelerin İnterneti (IIoT) olarak adlandırılan sanayi akımı, işletmelere, daha verimli, daha büyük bir esneklikle, daha güvenli ve daha çevre dostu bir şekilde üretim yapma imkanı sunmaktadır. Nesnelerin İnterneti ile bağlantılı yeni teknoloji ve hizmetler birçok endüstriyel uygulamada devrim niteliği taşımaktadır. Fabrikalardaki otomasyon, tahminleyici bakım (PdM – Predictive...
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Central Vagotonic Effects of Atropine Modulate Spectral Oscillations of Sympathetic Nerve Activity
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Deep Learning-Based, Multiclass Approach to Cancer Classification on Liquid Biopsy Data
PublikacjaThe field of cancer diagnostics has been revolutionized by liquid biopsies, which offer a bridge between laboratory research and clinical settings. These tests are less invasive than traditional biopsies and more convenient than routine imaging methods. Liquid biopsies allow studying of tumor-derived markers in bodily fluids, enabling the development of more precise cancer diagnostic tests for screening, disease monitoring, and...
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Mechanical, durability, depolluting and electrical properties of multifunctional mortars prepared with commercial or waste carbon-based fillers
PublikacjaCarbon-based fillers from industrial wastes and commercial ones were compared to improve the properties of lime-based mixes. As commercial fillers, graphene nanoplatelets and activated carbon were used, whereas as industrial wastes a char obtained by the gasification of biomasses and a used foundry sand were chosen. Carbon-based wastes were found to be a good cost-effective alternative to commercial carbon based fillers to increase...
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From ashes to porous hierarchical nanocarbon electrode: Upcycling secondary waste materials through self-catalytic chemical vapour deposition
PublikacjaMetal and metal oxide particles are abundant in various ash-based wastes. Utilizing these as catalyst sources for the fabrication of carbon nanomaterials could present a valuable approach to reduce our reliance on non-renewable and costly catalyst sources, thereby facilitating large-scale nanomaterial production. In this context, secondary waste materials (SWMs) are by-products resulting from the (complete or partial) combustion...
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Knowledge Management Approaches of Small and Medium-Sized KIBS Firms: a Descriptive Analysis of Four Countries
PublikacjaPurpose –There is evidence that small and medium sized enterprises (SMEs) do not manage knowledge the same way as large firms, and that they approach knowledge management (KM) in various ways. However, the literature on this topic is still scarce and fragmented. In order to fill this gap, the paper aims to single out and discuss the different features that characterize the approaches to KM adopted by small companies. Design/methodology/approach...
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Exploring the meaning of night shift placement in nursing education: A European multicentre qualitative study
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A characterization of peanut consumption in four countries: results from focus groups and their implications for peanut allergy prevalence
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Comparative study on the effectiveness of various types of road traffic intensity detectors
PublikacjaVehicle detection and speed measurements are crucial tasks in traffic monitoring systems. In this work, we focus on several types of electronic sensors, operating on different physical principles in order to compare their effectiveness in real traffic conditions. Commercial solutions are based on road tubes, microwave sensors, LiDARs, and video cameras. Distributed traffic monitoring systems require a high number of monitoring...
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Knowledge management approaches of small and medium-sized firms: a cluster analysis
PublikacjaPurpose This paper aims to categorise the approaches to knowledge management (KM) by companies. In the literature, there is no consensus on a universal or “best” approach to KM. Especially, this paper singles out and discusses the variegated features that characterise the implementation of KM by small- and medium-sized enterprises (SMEs) having different characteristics. Design/methodology/approach A cluster analysis was used...
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Higher Responsiveness to Rosuvastatin in Polygenic versus Monogenic Hypercholesterolemia: A Propensity Score Analysis
PublikacjaBackground: The monogenic defect in familial hypercholesterolemia (FH) is detected in ∼40% of cases. The majority of mutation-negative patients have a polygenic cause of high LDL-cholesterol (LDL-C). We sought to investigate whether the underlying monogenic or polygenic defect is associated with the response to rosuvastatin. Methods: FH Individuals were tested for mutations in LDLR and APOB genes. A previously established LDL-C-specific...
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IoT protocols, architectures, and applications
PublikacjaThe proliferation of embedded systems, wireless technologies, and Internet protocols have enabled the IoT to bridge the gap between the virtual and physical world enabling the monitoring and control of the environment by data processing systems. IoT refers to the inter-networking of everyday objects that are equipped with sensing, computation, and communication capabilities. These networks can collaboratively interact and perform...
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Electronic structure of intertwined kagome, honeycomb, and triangular sublattices of the intermetallics MCo2Al9 ( M = Sr, Ba)
PublikacjaIntermetallics are an important playground to stabilize a large variety of physical phenomena, arising from their complex crystal structure. The ease of their chemical tunabilty makes them suitable platforms to realize targeted electronic properties starting from the symmetries hidden in their unit cell. Here, we investigate the family of the recently discovered intermetallics MCo2Al9 (M=Sr, Ba) and we unveil their electronic structure....
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The beneficial use of nitric oxide during cardiopulmonary bypass on postoperative outcomes in children and adult patients: a systematic review and meta-analysis of 2897 patients
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Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia
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Platelet RNA Sequencing Data Through the Lens of Machine Learning
PublikacjaLiquid biopsies offer minimally invasive diagnosis and monitoring of cancer disease. This biosource is often analyzed using sequencing, which generates highly complex data that can be used using machine learning tools. Nevertheless, validating the clinical applications of such methods is challenging. It requires: (a) using data from many patients; (b) verifying potential bias concerning sample collection; and (c) adding interpretability...
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Investigation on the Sources and Impact of Trace Elements in the Annual Snowpack and the Firn in the Hansbreen (Southwest Spitsbergen)
PublikacjaWe present a thorough evaluation of the water soluble fraction of the trace element composition (Ca, Sr, Mg, Na, K, Li, B, Rb, U, Ni, Co, As, Cs, Cd, Mo, Se, Eu, Ba, V, Ge, Ga, Cr, Cr, P, Ti, Mn, Zr, Ce, Zn, Fe, Gd, Y, Pb, Bi, Yb, Al, Nb, Er, Nd, Dy, Sm, Ho, Th, La, Lu, Tm, Pr, Tb, Fe, In, Tl) and their fluxes in the annual snowpack and the firn of the Hansbreen (a tidewater glacier terminating in the Hornsund fjord, southwest...
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Health-related quality of life data from a phase 3, international, randomized, open-label, multicenter study in patients with previously treated mantle cell lymphoma treated with ibrutinib versus temsirolimus
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The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses ood intake and food-reinforced behavior but does not induce signs of nausea in rats
PublikacjaPrzeprowadzone badania biochemiczne wykazują, że związek AM4113 wiąże się z receptorem kanabinoidowym CB1, ale nie wykazuje właściwości odwrotnego agonisty (między innymi nie wpływa na powstawanie cyklicznego AMP). W testach na swobodne przemieszczanie się szczurów i znieczulenie związek AM4113 osłabia wpływ agonisty AM411 na receptor CB1. AM4113 wpływa na zachowanie szczurów związane z karmieniem oraz powoduje spadek łaknienia...
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Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study
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Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer
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The significant impact of age on the clinical outcomes of laparoscopic appendectomy
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Risk factors for serious morbidity, prolonged length of stay and hospital readmission after laparoscopic appendectomy - results from Pol-LA (Polish Laparoscopic Appendectomy) multicenter large cohort study
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Author Correction: Risk factors for serious morbidity, prolonged length of stay and hospital readmission after laparoscopic appendectomy - results from Pol-LA (Polish Laparoscopic Appendectomy) multicenter large cohort study
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Gendered Self-Views Across 62 Countries: A Test of Competing Models
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Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations
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Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study
PublikacjaThe variable configuration of Raman spectroscopic platforms is one of the major obstacles in establishing Raman spectroscopy as a valuable physicochemical method within real-world scenarios such as clinical diagnostics. For such real world applications like diagnostic classification, the models should ideally be usable to predict data from different setups. Whether it is done by training a rugged model with data from many setups...
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10Kin1day: A Bottom-Up Neuroimaging Initiative
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10Kin1day: A bottom-up neuroimaging initiative
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Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study
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coMpliAnce with evideNce-based cliniCal guidelines in the managemenT of acute biliaRy pancreAtitis): The MANCTRA-1 international audit
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Correction: Surgeons’ perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts: results from an international survey
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Time for a paradigm shift in shared decision-making in trauma and emergency surgery? Results from an international survey
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Surgeons’ perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts: results from an international survey
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Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
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Correction to: Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
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Effect of BMI on safety of bariatric surgery during the COVID-19 pandemic, procedure choice, and safety protocols – An analysis from the GENEVA Study
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30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data
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Safety of Bariatric Surgery in ≥ 65-Year-Old Patients During the COVID-19 Pandemic
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30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries
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Surgeons’ practice and preferences for the anal fissure treatment: results from an international survey
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Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries
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Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
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Global variation in anastomosis and end colostomy formation following left‐sided colorectal resection
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