Filtry
wszystkich: 358
wybranych: 324
Wyniki wyszukiwania dla: gambit czluchowski
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Scuffing and rolling contact fatigue resistance of discrete laser spot hardened austempered ductile iron
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Regulation of the switch from early to late bacteriophage λ DNA replication
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Substrate Reduction Therapies for Mucopolysaccharidoses
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Osteoprotegerin gene polymorphism in diabetic Charcot neuroarthropathy
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Column base fixity in steel moment frames: Observations from instrumented buildings
PublikacjaThe rotational fixity of column base connections in Steel Moment Resisting Frames (SMRFs) strongly influences their seismic response. However, approaches for estimating base fixity have been validated only against laboratory test data. These approaches are examined based on strong motion recordings from four instrumented SMRF buildings in California to informbest practices for seismic response simulation. These buildings represent...
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Effects of Column Base Flexibility on Seismic Response of Steel Moment-Frame Buildings
PublikacjaSteel Moment Resisting Frames (SMRFs) are very popular lateral load resisting systems in many seismically active regions. However, their seismic response is strongly dependent on the rotational fixity of column base connections. Despite many studies (both experimental and numerical) in this particular area, available approaches for estimating column base flexibility have been validated only against laboratory test data. In the...
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Lotne kwasy tłuszczowe na składowisku odpadów: występowanie i oznaczanie = Volatile Fatty Acids in a landfill: occurrence and determination
PublikacjaLotne kwasy tłuszczowe (LKT) powstają podczas biodegradacji materii organicznej i dlatego są także obecne na składowiskach odpadów, gdzie odgrywają kluczową rolę w przetwarzaniu materii organicznej w metan. Optymalizacja tego procesu wymaga znajomości i kontroli stężenia LKT, a ponieważ one mają również negatywny wpływ na środowisko, ich zawartość powinna być monitorowana w odciekach surowych i oczyszczonych oraz ich odbieralnikach...
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Lipids and Lipid Mediators Associated with the Risk and Pathology of Ischemic Stroke
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Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis.
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Implementation of Solute Transport in the Vadose Zone into the “HYDRUS Package for MODFLOW”
PublikacjaThe “HYDRUS package for MODFLOW” is an existing MODFLOW package that allows MODFLOW to simultaneously evaluate transient water flow in both unsaturated and saturated zones. The package is based on incorporating parts of the HYDRUS‐1D model (to simulate unsaturated water flow in the vadose zone) into MODFLOW (to simulate saturated groundwater flow). The coupled model is effective in addressing spatially variable saturated‐unsaturated...
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Updating the Coupling Algorithm between HYDRUS and MODFLOW in the HYDRUS Package for MODFLOW
PublikacjaThe HYDRUS-based flow package for MODFLOW (the HPM or the HYDRUS package) is an existing unsaturated zone flow package for MODFLOW. In MODFLOW with the HPM, the groundwater modeling domain is discretized into regular grids that can be combined into multiple zones based on similarities in soil hydrology, topographical characteristics, and the depth to the groundwater. Each of these zones is assigned one unsaturated soil profile...
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Improving Accuracy of Respiratory Rate Estimation by Restoring High Resolution Features With Transformers and Recursive Convolutional Models
PublikacjaNon-contact evaluation of vital signs has been becoming increasingly important, especially in light of the COVID- 19 pandemic, which is causing the whole world to examine people’s interactions in public places at a scale never seen before. However, evaluating one’s vital signs can be a relatively complex procedure, which requires both time and physical contact between examiner and examinee. These re- quirements limit the number...
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Self-Association of Amphotericin B: Spontaneous Formation of Molecular Structures Responsible for the Toxic Side Effects of the Antibiotic
PublikacjaAmphotericin B (AmB) is a lifesaving antibiotic used to treat deep-seated mycotic infections. Both the pharmaceutical activity and highly toxic side effects of the drug rely on its interaction with biomembranes, which is governed by the molecular organization of AmB. In the present work we present detailed analysis of self-assembly of AmB molecules in different environments, interesting from the physiological standpoint, based...
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Self-assembly, stability and conductance of amphotericin B channels: bridging the gap between structure and function
PublikacjaAmphotericin B (AmB), one of the most powerful but also toxic drugs used to treat systemic mycoses, is believed to selectively permeabilize fungal cell membranes to ions in a sterol-dependent manner. Unfortunately, the structure of the biologically active AmB channels has long eluded researchers, obstructing the design of safer alternatives. Here, we investigate the structural and thermodynamic aspects of channel formation, stability,...
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Technika zwielokrotnionego nadawania i zbiorczego odbioru w telekomunikacji bezprzewodowej
PublikacjaPrzedstawiona technika, która będzie w pełni zastosowana w systemach trzeciej i czwartej generacji, umożliwia wydatne zwiększenie możliwości transmisyjnych toru nadawczo-odbiorczego. W wyniku tego oczekuje się uzyskanie przepływności ruchomych kanałów radiokomunikacyjnych do poziomu porównywalnego z tym, co aktualnie oferują stałe łącza światłowodowe. Oczekuje się, że pierwszym obszarem zastosowań opisanej techniki będą sieci WLAN...
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Expression of genes involved in neurogenesis, and neuronal precursor cell proliferation and development: Novel pathways of human ovarian granulosa cell differentiation and transdifferentiation capability in�vitro
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Differential expression profile between amygdala and blood during chronic lithium treatment in a rat model of depression – a pilot study
PublikacjaLithium is a mood stabilizer widely used in the pharmacotherapy of bipolar disorder and treatment‑resistant depression. Taking into account dysregulated inflammatory activity in depression and the immunomodulatory role of lithium, we hypothesized that genes associated with inflammatory responses may be potential biomarkers of lithium action. We aimed to compare gene expression changes between the brain and the periphery after...
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Micro and Macroelements in Honey and Atmospheric Pollution (NW and Central Poland)
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Is the Concept of Zero Waste Possible to Implement in Construction?
PublikacjaThe scientifically treated problem of reusing building materials appeared in the literature more than 50 years ago. This paper includes an analysis of the characteristics of recycled building materials, which is a prerequisite for rational recycling. The analysis and simulation of building stocks at different scales has led to the conclusion that the most important link in the transformation of the construction industry towards...
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Mechanism of Binding of Antifungal Antibiotic Amphotericin B to Lipid Membranes: An Insight from Combined Single-Membrane Imaging, Microspectroscopy, and Molecular Dynamics
PublikacjaAmphotericin B is a lifesaving polyene antibiotic used in the treatment of systemic mycoses. Unfortunately, the pharmacological applicability of this drug is limited because of its severe toxic side effects. At the same time, the lack of a well-defined mechanism of selectivity hampers the efforts to rationally design safer derivatives. As the drug primarily targets the biomembranes of both fungi and humans, new insights into the...
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Genes regulating programmed cell death are significantly upregulated in porcine immature oocytes
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Flow Control Algorithm for UMTS HSDPA
PublikacjaHSDPA (High Speed Downlink Packet Access) jest istotnym etapem ewolucji systemu UMTS. Pozwala na transmisję do użytkownika z prędkością dochodzącą do 14.4 Mbit/s; aby to umożliwić, wprowadzono w wersji 5 UMTS szereg nowych mechanizmów w warstwie fizycznej oraz MAC. W tej pracy przedstawiono szczegółową analizę jednego z nowych mechanizmów - algorytmu kontroli natężenia ruchu między MAC-hs i MAC-d. Zaproponowano nowy, efektywny...
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Novel markers of human ovarian granulosa cell differentiation toward osteoblast lineage: A microarray approach
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Analysis of expression of genes responsible for regulation of cellular proliferation and migration – microarray approach based on porcine oocyte model
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Preferred Benchmarking Criteria for Systematic Taxonomy of Embedded Platforms (STEP) in Human System Interaction Systems
PublikacjaThe rate of progress in the field of Artificial Intelligence (AI) and Machine Learning (ML) has significantly increased over the past ten years and continues to accelerate. Since then, AI has made the leap from research case studies to real production ready applications. The significance of this growth cannot be undermined as it catalyzed the very nature of computing. Conventional platforms struggle to achieve greater performance...
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A new potential mode of cardiorenal protection of KLOTHO gene variability in type 1 diabetic adolescents
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Abnormal Sphingolipid World in Inflammation Specific for Lysosomal Storage Diseases and Skin Disorders
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Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases
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Models in the Research Process of Psoriasis
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Non-steroidal anti-inflammatory drugs are safe with respect to the transcriptome of human dermal fibroblasts
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Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2
PublikacjaW pracy zidentyfikowaliśmy elementy struktury chemicznej dla 23 pochodnych imidazoakrydonu odpowiedzialne za ich rozpoznawanie przez transporter typu ABC, białko ABCG2. za transport tych związków przez pompę ABCG2 odpowiedzialne jest grupa hydroksylowa w pozycjach R1, R2 i R3 chromoforu. Stwierdziliśmy także, że zwiększanie ilości grup metylenowych łańcucha bocznego imidazoakrydonów powodowało zmniejszenie aktywnego transportu...
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Fully Automated AI-powered Contactless Cough Detection based on Pixel Value Dynamics Occurring within Facial Regions
PublikacjaIncreased interest in non-contact evaluation of the health state has led to higher expectations for delivering automated and reliable solutions that can be conveniently used during daily activities. Although some solutions for cough detection exist, they suffer from a series of limitations. Some of them rely on gesture or body pose recognition, which might not be possible in cases of occlusions, closer camera distances or impediments...
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Identifying Selected Tram Transport Risks
PublikacjaIn the area of transport infrastructure risks, infrastructure is inspected for safety. It is an element of transport safety management based on risk management and forms part of preventative activities and measures. As regards tram infrastructure which is a component of urban transport infrastructure, there are potential collisions with cars, cyclists and pedestrians. Data from Gdansk Buses and Trams...
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Actinidia (Mini Kiwi) Fruit Quality in Relation to Summer Cutting
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Actinidia (Mini Kiwi) Fruit Quality in Relation to Summer Cutting
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Estimation of smokers' exposure to mercury from combustible tobacco products, based on the approach used in food consumers’ exposure estimation
PublikacjaSmoking has been known to mankind for centuries, but it is only in recent decades that much attention has been paid to the harmfulness of this habit. Mercury inhalation is particularly dangerous in this respect and smoking creates extremely favorable conditions for the emission and targeted delivery of this element into the lungs. Despite this fact, a lack of a clear method for estimating the exposure of tobacco consumers to mercury...
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Badania statystyczne rezystancji izolacji silników szeregowych prądu stałego typu BGK pojazdów Dűwag N8C w wersji przed modernizacją, mające na celu ustalenie przyczyny występowania uszkodzeń tego typu silników – wyniki ekspertyzy
PublikacjaTramwaje serii N8C są największą liczebnie grupą pojazdów szynowych we flocie GAiT. Zgodnie z informacjami pozyskanymi od przewoźnika, w ostatnim czasie zaobserwowano zwiększenie częstości występowania uszkodzeń silników trakcyjnych tych pojazdów widoczne zwłaszcza dla wozów stacjonujących w zajezdni Nowy Port. Celem wyjaśnienia przyczyny tego stanu rzeczy wykonano statystyczne badania rezystancji izolacji uzwojeń wszystkich silników...
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Putative Biological Mechanisms of Efficiency of Substrate Reduction Therapies for Mucopolysaccharidoses
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Significant Down-Regulation of “Biological Adhesion” Genes in Porcine Oocytes after IVM
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New Gene Markers for Metabolic Processes and Homeostasis in Porcine Buccal Pouch Mucosa during Cells Long Term-Cultivation—A Primary Culture Approach
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Genes encoding proteins regulating fatty acid metabolism and cellular response to lipids are differentially expressed in porcine luminal epithelium during long-term culture
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Investigation of optical properties of Infitec and Active Stereo stereoscopic techniques for CAVE-type virtual reality systems
PublikacjaIn recent years, many scientific and industrial centres in the world developed virtual reality systems or laboratories. At present, among the most advanced virtual reality systems are CAVE-type (Cave Automatic Virtual Environment) installations. Such systems usually consist of four, five, or six projection screens arranged in the form of a closed or hemi-closed space. The basic task of such systems is to ensure the effect of user...
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Architekturführer Danzig: Gdansk Sopot Gdynia
PublikacjaIm Zweiten Weltkrieg bis auf die Grundmauern zerstört, wurde der historische Stadtkern der Hansestadt Danzig als polnisches Gdańsk wiederaufgebaut – ein Paradebeispiel für kritische Rekonstruktion in Polen und zugleich eine bis heute stark umstrittene Entscheidung. Zusammen mit dem mondänen Seebad Sopot und der modernen Hafenstadt Gdynia bildet die Bernsteinstadt eine Metropolregion an der polnischen Ostseeküste: die Dreistadt...
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Gustav Oelsners Werk aus polnischer Perspektive. das Erbe der moderne in der polnischen Architektur und Stadtplannung
PublikacjaDie Leistungen des Architekten Gustav Oelsner sind ein Beispiel für das gemeinsame Erbe der Region, das gemeinsam betrachtet werden sollte – ohne eine de facto künstliche Aufteilung in die Aktivitäten deutscher und polnischer Künstler. Eine solche Herangehensweise ist notwendig bei der Analyse der Biographie nicht nur des Altonaer Architekten, sondern vieler anderer, die das Schicksal der Geschichte in die nationale Einteilung...
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Effect of Base-Connection Strength and Ductility on the Seismic Performance of Steel Moment-Resisting Frames
PublikacjaColumn-base connections in steel moment-resisting frames (SMFs) in seismic regions are commonly designed to develop the capacity of adjoining column with an intent to develop a plastic hinge in the column member, rather than in the connection (i.e., a strong-base design). Recent research has shown base connections to possess high ductility, indicating that this practice may be not only expensive but also unnecessary. This suggests...
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Composites in energy storing prosthetic feet
PublikacjaComposites reinforced with carbon and glass fibers have become the commonly used material in the production of energy storing prosthetic feet (ESPF/elastic feet prostheses). Their properties ensure a stable and light structure that allows for accumulation, storage and release of energy during walking, thus ensuring an increase in gait efficiency. Depending on the modification of the composite in terms of fiber selection, their...
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Molecular organization of antifungal antibiotic amphotericin B in lipid monolayers studied by means of Fluorescence Lifetime Imaging Microscopy
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The lipid composition of Legionella dumoffii membrane modulates the interaction with Galleria mellonella apolipophorin III
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Expression Changes in Fatty acid Metabolic Processrelated Genes in Porcine Oocytes During in Vitro Maturation
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Maternal smoking Modulates Fatty Acid Profile of Breast Milk
PublikacjaAIM: We hypothesized that the fatty acid composition of breast milk can be affected by a smoking habit in the mother. Consequently, this study verified whether maternal smoking modulates, and if so to what extent, the breast milk fatty acid profile. METHODS: The study included 20 postpartum women who declared smoking more than five cigarettes daily throughout a period of pregnancy and lactation, and 136 non-smoking postpartum women....