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Wyniki wyszukiwania dla: reverse transcriptase
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Optimal conditions of ramentaceone and plumbagin separation and isolation from carnivorous plants extracts using reverse phase-high performance liquid chromatography (RP-HPLC)
PublikacjaPreparatywna chromatografia cieczowa jest szczególnie przydatną techniką do rozdzielania i izolacji użytecznych ilości substancji z różnych skomplikowanych mieszanin. Praca prezentuje optymalne warunki rozdzielania i izolacji ramentaceonu i plumbaginy uwzględniając maksymalną selektywność rozdzielania naftochinonów od substancji balastowych z chloroformowych ekstraktów roślinnych D. aliciae i D. capensis z zastosowaniem techniki...
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Moderate-to-severe obstructive sleep apnea is associated with telomere lengthening
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Severe hypodysfibrinogenemia in a young patient with pulmonary thromboembolism: a case report
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Numerical assessment of ultimate strength of severe corroded stiffened plates
PublikacjaThe objective of this work is to investigate numerically (using the non-linear FEM and the approach stipulated by the Common Structural Rules) the severe nonuniform corrosion degradation effect on the ultimate strength of stiffened plates and compare the results to the already published experimental works. Different factors governing structural behavior of corroded stiffened plates are investigated, such as corrosion degradation level,...
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IEEE Working Conference on Reverse Engineering
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Comparative analysis of mRNA transcripts of HT-29 cell line expressed in identical quantities for pathogenic E. coli strains UM146 and UM147 with control Escherichia coli Nissle 1917
PublikacjaAim of study was comparative analysis of mRNA transcripts of HT-29 cell line, expressed in identical quantities for the combination of pathogenic and non-pathogenic Escherichia coli strains. HT-29 confluent monolayers infection with two pathogenic E. coli strains UM146 and UM147 resulted in two sets of mRNA transcripts that were identical with RNA transcripts obtained for non-pathogenic one strain E. coli Nissle 1917. In this study...
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Synthesis of sol-gel mesoporous silica materials providing a slow release of doxorubicin
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Application of the simplified models to inverse flood routing in upper Narew river(Poland)
PublikacjaW pracy przedstawiono rozwiązanie zagadnienia odwrotnej transformacji przepływów z zastosowaniem uproszczonych modeli. Zastosowano model fali kinematycznej oraz równanie retencji. W pierwszym przypadku równanie całkowano w kierunku malejącego czasu zaś w drugim w kierunku przeciwnym do przepływu. Wykazano, że obydwa podejścia są równoważne. Modele zastosowano dla górnego odcinka Narwi.
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Expedited Geometry Scaling of Compact Microwave Passives by Means of Inverse Surrogate Modeling
PublikacjaIn this paper, the problem of geometry scaling of compact microwave structures is investigated. As opposed to conventional structures (i.e., constructed using uniform transmission lines), re-design of miniaturized circuits (e.g., implemented with artificial transmission lines, ATSs) for different operating frequencies is far from being straightforward due to considerable cross-couplings between the circuit components. Here, we...
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The risk assessment of adverse events of nursing activities as the element of quality management in healhcare
PublikacjaThe purpose of the paper is to present MedCARVER+Shock method and Pareto analysis and its usability for the risk assessment of adverse events of nursing activities. 888 activities carried out by all 190 nurses working at the District Hospital X located in Poland were taken into account. During the research the qualitative approach was used. As the result sixteen groups of nursing activities causing the highest risk of adverse events...
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Inverse surrogate models for fast geometry scaling of miniaturized dual-band couplers
PublikacjaRe-design of microwave structures for various sets of performance specifications is a challenging task, particularly for compact components where considerable electromagnetic (EM) cross-couplings make the relationships between geometry parameters and the structure responses complex. Here, we address geometry scaling of miniaturized dual-band couplers by means of inverse surrogate modeling. Our approach allows for fast estimation...
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Release and Transport of Toxic, Mobile Organic Compounds (Formaldehyde and Phenols) on an Arctic Glacier
PublikacjaAs a result of current deglaciation, the chemical cycles of many compounds, including toxic formaldehyde and phenols, are changing. However, the processes by which these chemicals are released have yet to be studied in situ. Here, we quantify fluxes of HCHO and phenols in a glacial catchment within one summer season, obtaining a net release from the glacier of 0.106 · 106 g formaldehyde and 0.255 · 106 g phenols, which can be interpreted...
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Preferences Towards Working in Culturally Diverse Teams at Different Stages of the Entrepreneurial Process
PublikacjaAs entrepreneurial teams become prevalent, it is important to study factors related to their creation and effectiveness. The goal of the current research was to analyze preferences towards working in a multicultural team (MCT) versus a single culture team (SCT) at different stages of the entrepreneurial process. The study involved students originating from various cultures with previous experience in both SCTs and MCTs as participants....
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Rapid dimension scaling of triple-band antennas by means of inverse surrogate modeling
PublikacjaGeometry scaling of antennas, i.e., finding optimum dimensions of the structure for given operating conditions and material parameters is an important yet challenging problem. In this paper, we discuss fast dimension scaling of triple-band antennas with respect to operating frequencies. We adopt the inverse surrogate modeling approach where the surrogate model is a function of the three operating frequencies of the antenna and...
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Exposure to non-opioid analgesics during pregnancy and the risk of adverse drug reactions
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A Novel Delivery System for the Controlled Release~of Antimicrobial Peptides: Citropin 1.1 and Temporin A
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Development of biodegradable polyesters with various microstructures for highly controlled release of epirubicin and cyclophosphamide
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Unmasking the COVID-19 Pandemic Prevention Gains: Excess Mortality Reversal in 2022
PublikacjaObjectives: The purpose of this study was to assess the long-term effectiveness of COVID-19 pandemic prevention measures in saving lives after European governments began to lift restrictions. Study design: Excess mortality interrupted time series.Methods: Country-level weekly data on deaths were fitted to the Poisson mixed linear model to estimate excess deaths. Based on this estimate, the percentage of excess deaths...
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INTELLECTUALS IN THE FACE OF HISTORIC TURMOIL: “THE REVENGE OF THE PRINTER” BY STANISLAV ROSOVETSKYJ AS ACADEMIC FICTION
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Magnetization Reversal Mechanism in Exchange-Biased Spring-like Thin-Film Composite
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Unraveling the Protective Effects of Cognitive Reserve on Cognition and Brain: A Cross-Sectional Study
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Effects of Single and Repeated Footshock on Dopamine Release and Metabolism in the Brains of Fischer Rats
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Self-ignition of hydrogen–nitrogen mixtures during high-pressure release into air
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Unmasking the COVID-19 pandemic prevention gains: excess mortality reversal in 2022
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Inverse surrogate modeling for low-cost geometry scaling of microwave and antenna structures
PublikacjaPurpose–The purpose of this paper is to investigate strategies for expedited dimension scaling ofelectromagnetic (EM)-simulated microwave and antenna structures, exploiting the concept of variable-fidelity inverse surrogate modeling.Design/methodology/approach–A fast inverse surrogate modeling technique is described fordimension scaling of microwave and antenna structures. The model is established using referencedesigns obtained...
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Stable and degradable microgels linked with cystine for storing and environmentally triggered release of drugs
PublikacjaEnvironmentally sensitive, degradable microgels based on poly(N-isopropylacrylamide) (pNIPA) crosslinked with the diacryloyl derivative of cystine (BISS) were synthesized by applying surfactant-free emulsion polymerization. pNIPA contributed the sensitivity to temperature to the microgels and the cross-linker made them degradable and sensitive to pH. The morphology of the microgels was investigated by using scanning and transmission...
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Comparison of direct and inverse methods of satellite observations downscaling for the coastal zone area
PublikacjaThe Earth observation satellite imaging systems have known limitations, especially regarding their spatial and temporal resolution. Therefore, approaches which aim to combine data retrieved from sensors of higher temporal and lower spatial resolution with the data characterized by lower temporal but higher spatial resolution are of high interest. This allows for joint utilization of the advantages of both these types of sensors....
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Probabilistic estimation of diverse soil condition impact on vertical axis tank deformation
PublikacjaThe calculations of fuel tanks should take into account the geometric imperfections of the structure as well as the variability of the material parameters of the foundation. The deformation of the tank shell can have a significant impact on the limit state of the structure and its operating conditions. The paper presents a probabilistic analysis of a vertical-axis, floating-roof cylindrical shell of a tank with a capacity of 50000...
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Accelerated Re-Design of Antenna Structures Using Sensitivity-Based Inverse Surrogates
PublikacjaThe paper proposes a novel framework for accelerated re-design (dimension scaling) of antenna structures using inverse surrogates. The major contribution of the work is a sensitivity-based model identification procedure, which permits a significant reduction of the number of reference designs required to render the surrogate. Rigorous formulation of the approach is supplemented by its comprehensive numerical validation using a...
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Globalized parametric optimization of microwave components by means of response features and inverse metamodels
PublikacjaSimulation-based optimization of geometry parameters is an inherent and important stage of microwave design process. To ensure reliability, the optimization process is normally carried out using full-wave electromagnetic (EM) simulation tools, which entails significant computational overhead. This becomes a serious bottleneck especially if global search is required (e.g., design of miniaturized structures, dimension scaling over...
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Global Design Optimization of Microwave Circuits Using Response Feature Inverse Surrogates
PublikacjaModern microwave design has become heavily reliant on full-wave electromagnetic (EM) simulation tools, which are necessary for accurate evaluation of microwave components. Consequently, it is also indispensable for their development, especially the adjustment of geometry parameters, oriented towards performance improvement. However, EM-driven optimization procedures incur considerable computational expenses, which may become impractical...
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Isolation Improvement in MIMO Antenna with a Simple Hybrid Technique of Orthogonal and Inverse Currents
PublikacjaThis paper presents a compact high-isolation multiple-input multiple-output (MIMO) antenna developed using a hybrid approach. The proposed technique combines induced orthogonal currents and self-inverse currents to enhance the antenna's performance. Orthogonal currents are generated by strategically etching open slots on the antenna patches, while self-inverse currents are introduced by integration of annular vias. By carefully...
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High-Dose Testosterone Propionate Treatment Reverses the Effects of Endurance Training on Myocardial Antioxidant Defenses in Adolescent Male Rats
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Journal of Interlibrary Loan, Document Delivery and Electronic Reserve
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In silico design of telomerase inhibitors.
PublikacjaTelomerase is a reverse transcriptase enzyme involved in DNA synthesis at the end of linear chromosomes. Unlike in most other cells, telomerase is reactivated most cancerous cells and, therefore, has become a promising new anticancer target. Despite extensive research, direct telomerase inhibitors have yet not been introduced to the clinics because of the complexity of this enzyme. Structures of this protein from simple organisms...
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Multimodal Approach For Polysensory Stimulation And Diagnosis Of Subjects With Severe Communication Disorders
Publikacjais evaluated on 9 patients, data analysis methods are described, and experiments of correlating Glasgow Coma Scale with extracted features describing subjects performance in therapeutic exercises exploiting EEG and eyetracker are presented. Performance metrics are proposed, and k-means clusters used to define concepts for mental states related to EEG and eyetracking activity. Finally, it is shown that the strongest correlations...
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The effect of disturbance caused by rivers flooding on ground beetles (Coleoptera: Carabidae)
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Internalized stigma and its correlates among patients with severe mental illness
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Severe oxidatively damaged DNA after cisplatin treatment of cancer patients
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Influence of Boron Carbide on Core Degradation During Severe Accidents in LWRs
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The efficiency comparison of ramentaceone isolation from Drosera aliciae plants using normal and reversed phase preparative liquid chromatography technique
PublikacjaW pracy zaprezentowano optymalne warunki otrzymywania ramentaceonu z chloroformowego ekstraktu z rośliny D. muscipula. Opracowano i przedstawiono dwie procedury otrzymywania ramantaceonu z wykorzystaniem NP-PLC i RP-PLC. Dla produktu o określonej czystości, porównano maksymalny stopień przeładowania kolumny, efektywność procesu wyrażoną jako ilość substancji otrzymanej w jednostce czasu oraz produktywność kolumny, wyrażoną jako...
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Rapid and sensitive determination of acrylamide in potato crisps using reversed-phase direct immersion single drop microextraction-gas chromatography
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Discrepancies in determination of biogenic amines in beer samples by reversed phase and hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry
PublikacjaBiogenic amines (BAs) are nitrogenous organic bases occurring mainly in fermented food and beverages as a result of free amino acids bacterial decarboxylation. The reversed phase liquid chromatography (RPLC) and hydrophilic interaction liquid chromatography (HILIC) based methods were compared in terms of usefulness for determination of BAs in beer samples. Analysis of BAs with the use of RPLC method were carried out after their...
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Comparison of conventional tacrolimus versus prolong release formula as initial therapy in heart transplantation
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The Effect of PEG Concentration on the Release Rate of Cisplatin from PEG-Modified Silica Xerogels
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Geographic information system for remote integration of diverse under-water acoustic sensor data
PublikacjaMaritime and port areas throughout the world are exposed to many different hazards, like pollution, terrorism and natural disasters. Early detection, identification and preparation of appropriateesponse strategies is especially important in the case of semi-enclosed basins like the Baltic Sea, mainly due to the marine ecosystems' continuous absorption of pollutants including oil, heavy metals and chemicals. Many of those agents...
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ENCAPSULATION OF ROXITHROMYCIN INTO GELLAN GUM MATRICES AND THE IMPACT OF OTHER NATURAL POLYMERS ON DRUG RELEASE
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On the estimation of the design loads on container stacks due to excessive acceleration in adverse weather conditions
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Assessing the Influence of a Rotating Magnetic Field on Ibuprofen Permeability from Diverse Pharmaceutical Formulations
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A European-wide dataset to uncover adaptive traits of Listeria monocytogenes to diverse ecological niches
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