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Search results for: PATH
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Assessing pathways into a low carbon and climate responsible Gdansk
PublicationA basic question today is the sense of the use new ideas in shaping Polish cities- not as technologically advanced as others. The key is to understand good practices in designing and implementing new approaches. The comparative research Glasgow and Gdansk has been undertaken by Gdansk Development Agency in Jan 2014
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Argon plasma-modified bacterial cellulose filters for protection against respiratory pathogens
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Spectrum of Bacterial Pathogens from Urinary Infections Associated with Struvite and Metabolic Stones
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Various modes of action of dietary phytochemicals, sulforaphane and phenethyl isothiocyanate, on pathogenic bacteria
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Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids
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Voriconazole-Based Salts Are Active against Multidrug-Resistant Human Pathogenic Yeasts
PublicationVoriconazole (VOR) hydrochloride is unequivocally converted into VOR lactates and valinates upon reaction with silver salts of organic acids. This study found that the anticandidal in vitro activity of these compounds was comparable or slightly better than that of VOR. The Candida albicans clinical isolate overexpressing CaCDR1/CaCDR2 genes, highly resistant to VOR, was apparently more susceptible to VOR salts. On the other hand,...
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Self-healing ATM networks based on preplanned restoration of virtual paths
PublicationW pracy omówiono klasyfikację metod odtwarzania usług w samonaprawialnych sieciach ATM opartych na ścieżkach wirtualnych i o topologii kratkowej. Przedstawiono model z zaplanowanymi z góry ścieżkami zabezpieczającymi i wyniki badań przykładowej sieci w Polsce.
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Conducted EMI Propagation Paths in DC-AC Hard Switching Converter
PublicationIn order to limit the electromagnetic interference (EMI) in power electronics devices, knowledge about the phenomena connected with EMI generation and propagation is necessary. This papers describes the propagation paths in the 3 phase voltage source inverter using wide-band simulation and laboratory test with the signal processing method Wiener filtering, where the transfer functions between voltage across switches and the perturbation...
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Network Graph Transformation Providing Fast Calculation of Paths for Resilient Routing
PublicationProtection of transmission against failures can be appropriately dealt with by alternative paths. However, common schemes (e.g., Bhandaris scheme) are characterized by a remarkable delay while determining the transmission paths. This in turn may have a serious impact on serving dynamic demands (characterized by relatively short duration time). As a remedy to this problem, we introduce an approach to pre-compute the sets of disjoint...
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Importance of oxidative stress in the pathogenesis, diagnosis, and monitoring of patients with neuropsychiatric disorders, a review
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Notch signalling pathway as an oncogenic factor involved in cancer development
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Flavonoid biosynthetic pathways in plants: Versatile targets for metabolic engineering
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A Process-Centered Approach to the Description of Clinical Pathways—Forms and Determinants
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Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways
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A strategy towards the generation of testable adverse outcome pathways for nanomaterials
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Methane formation over TiO2–based photocatalysts: reaction pathways
PublicationThe effects of organic impurities adsorbed or incorporated into semiconductors structure on the photocatalytic products are noteworthy. For this purpose, the as-prepared Ag, Au and Pdmodified TiO2 samples were exposed to UV-vis irradiation in various gas atmospheres (CO2, N2, 600 ppm CO2 in N2, and 13CO2) in order to clarify the route of CH4 formation in the process of photocatalytic CO2 reduction. In the presented research it...
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Molecular targets for antifungals in amino acid and protein biosynthetic pathways
PublicationFungi cause death of over 1.5 million people every year, while cutaneous mycoses are among the most common infections in the world. Mycoses vary greatly in severity, there are long-term skin (ringworm), nail or hair infections (tinea capitis), recurrent like vaginal candidiasis or severe, life-threatening systemic, multiorgan infections. In the last few years, increasing importance is attached to the health and economic problems...
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Application of Rotating Magnetic Fields Increase the Activity of Antimicrobials Against Wound Biofilm Pathogens
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Effects of stressful physico-chemical factors on the fitness of the plant pathogenic bacterium Dickeya solani
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Increased risk of thyroid pathology in patients with thyroid hemiagenesis: results of a large cohort case–control study
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Detection of the Plant Pathogen Pseudomonas Syringae pv. Lachrymans on Antibody-Modified Gold Electrodes by Electrochemical Impedance Spectroscopy
PublicationThe present work describes an impedimetric immunosensor for Pseudomonas syringae pv. lachrymans (Psl) detection. This pathogen infects many crop species causing considerable yield losses, thus fast and cheap detection method is in high demand. In the assay, the gold disc electrode was modified with 4-aminothiophenol (4-ATP), glutaraldehyde (GA), and anti-Psl antibodies, and free-sites were blocked with bovine serum albumin (BSA)....
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Attributions of educational and professional paths: Analysing reasons for adolescent and young adults choices
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Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis
PublicationPsoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors regulating gene expression play a key role. In the “genomic era”, genome-wide association studies together with target genotyping platforms performed in different ethnic populations have found more than 50 genetic susceptible markers associated with the risk of psoriasis which have been identified so far. Up till now, the strongest association...
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Pathogenesis of psoriasis in the “omic” era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis
PublicationPsoriasis is a systemic disease that is strictly connected with metabolic disorders (insulin resistance, atherogenic dyslipidemia, arterial hypertension, and cardiovascular diseases). It occurs more often in patients with a more severe course of the disease. Obesity is specially an independent risk factor and it is associated with a worse treatment outcome because of the high inflammatory activity of visceral fatty tissue and...
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AOP173 key event associated pathway predictor – online application for the prediction of benchmark dose lower bound (BMDLs) of a transcriptomic pathway involved in MWCNTs-induced lung fibrosis
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Comparison of pathological staging and grading of urothelial bladder carcinoma in post-transurethral resection and post-radical cystectomy specimens
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THE EFFECT OF ALTERNATIVE CUTTER PATHS ON FLATNESS DEVIATIONS IN THE FACE MILLING OF ALUMINUM PLATE PARTS
PublicationIn this paper the relationships between the alternative machining paths and flatness deviations of the aluminum plate part, were presented. The flatness tolerance of the main surface of the plate part has crucial meaning due to the assembly requirement of piezoelectric elements on the radiator. The aluminum bodies under investigation are the base part of the radiators with crimped feathers for the train industry. The surface of...
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Robustness of Pathway Enrichment Analysis to Transcriptome-Wide Gene Expression Platform
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Prevalence of human pathogens of the clade Nakaseomyces in a culture collection—the first report on Candida bracarensis in Poland
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CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures
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Nitrogen pathways during sewage treatment in constructed wetlands in temporary climate
PublicationThe objectives of this paper is to estimate the role and quantity of the unit process responsible for removal or/and retention of nitrogen in different types of constructed wetlands in vegetation season and outside vegetation season. To estimate the role of the plant two objects inhabited one with willow and the other with reed were selected to assessment. Among anthers it was indicated that the concentrations of contamination...
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Comparison of nitrogen and VFA removal pathways in autotrophic and organotrophic anammox reactors
PublicationOrganotrophic anammox is a promising process for treating both nitrogen and organic containing wastewater than that of the traditional autotrophic anammox for sole nitrogen removal. However pathways of nitrogen removal particularly at metagenomic level in both processes are still unknown. Here we report, metabolic pathways of nitrogen removal in two lab-scale sequencing batch reactors (SBR), one autotrophic and another organotrophic...
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The Activity of Isoquinoline Alkaloids and Extracts from Chelidonium majus against Pathogenic Bacteria and Candida sp.
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Critical factors for the performance of chip array-based electrical detection of DNA for analysis of pathogenic bacteria
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Transcriptomics‐Based and AOP‐Informed Structure–Activity Relationships to Predict Pulmonary Pathology Induced by Multiwalled Carbon Nanotubes
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Comparison of IP-based and explicit paths for one-to-one fast reroute in MPLS networks
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UGT1A1gene polymorphism as a potential factor inducing iron overload in the pathogenesis of type 1 hereditary hemochromatosis
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Pathogenesis of psoriasis in the “omic” era. Part I. Epidemiology, clinical manifestation, immunological and neuroendocrine disturbances
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Tissue Factor and Tissue Factor Pathway Inhibitor in Chronically Inflamed Gallbladder Mucosa
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Ball milling treatment of Mn3O4 regulates electron transfer pathway for peroxymonosulfate activation
PublicationHeterogeneous metal catalysts have attracted considerable interest in advanced oxidation processes (AOPs) for wastewater treatment by activating peroxymonosulfate (PMS). However, it remains challenging to the rational design of efficient reaction pathway for high-performance contaminants removal by regulating the inherent structure of metal oxides. Herein, a high-energy ball milling method was employed to modulate the electronic...
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In Vitro Evaluation of Polihexanide, Octenidine and NaClO/HClO-Based Antiseptics against Biofilm Formed by Wound Pathogens
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Structural changes of bacterial cellulose due to incubation in conditions simulating human plasma in the presence of selected pathogens
PublicationBacterial nanocellulose (BNC) is a natural biomaterial with a wide range of medical applications. However, it cannot be used as a biological implant of the circulatory system without checking whether it is biodegradable under human plasma conditions. This work aimed to investigate the BNC biodegradation by selected pathogens under conditions simulating human plasma. The BNC was incubated in simulated biological fluids with or...
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Cuticular fatty acids of Galleria mellonella (Lepidoptera) inhibit fungal enzymatic activities of pathogenic Conidiobolus coronatus
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Fibronectin-, vitronectin- and laminin-binding proteins at the cell walls of Candida parapsilosis and Candida tropicalis pathogenic yeasts
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The ability of selected plant essential oils to enhance the action of recommended antibiotics against pathogenic wound bacteria
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Panax quinquefolium hairy root extracts and their effect in connections with antibiotics against pathogenic bacteria – preliminary study
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In vitro biodegradation of bacterial nanocellulose under conditions simulating human plasma in the presence of selected pathogenic microorganisms
PublicationThe Biodegradability of bacterial nanocellulose (BNC) was assessed based on a change in its properties under conditions simulating human plasma in the presence or absence of the pathogens Staphylococcus aureus, Candida albicans and Aspergillus fumigatus. It was shown that the dry mass of BNC did not change during 6 months of incubation, except for samples stored in the presence of moulds, where the dry mass reduced by 40 %. The...
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Optimized IP-based vs. explicit paths for one-to-one backup in MPLS fast reroute
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