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Search results for: INDYVIDUAL SFTW
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The presence of bacterial microcolonies on the maxillary sinus ciliary epithelium in healthy young individuals
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Combining CDKN1A gene expression and genome-wide SNPs in a twin cohort to gain insight into the heritability of individual radiosensitivity
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Perceived technostress while learning a new mobile technology: Do individual differences and the way technology is presented matter?
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Analogues of Trypsin Inhibitor SFTI-1 with Disulfide Bridge Substituted by Various Length of Carbonyl Bridges
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Investigation of peptide splicing using two‐peptide‐chain analogs of trypsin inhibitor SFTI‐1
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Fluorescent analogs of trypsin inhibitor SFTI-1 isolated from sunflower seeds-synthesis and applications
PublicationThis article describes the synthesis and enzymatic study of newly synthesized analogs of trypsin inhibitors SFTI-1 that were fluorescent labeled on their N-terminal amino groups. Two fluorescent derivatives of benzoxazole (3-[2-(4-diphenylaminophenyl) benzoxazol-5-yl]-L-alanine[(4NPh(2)) Ph] Box-Ala and 3-[2-(2', 4', 5'-trimethoxyphenyl) benzoxazol-5-yl]-l-alanine-[2,4,5-(OMe)3Ph] Box-Ala) were used as efficient fluorescent labels....
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Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data
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Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI‐1 as a starting structure
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Conformational studies of [Nphe5]SFTI-1 by means of 2D NMR spectroscopy in conjunction with molecular dynamics calculations
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Spliced analogues of trypsin inhibitor SFTI‐1 and their application for tracing proteolysis and delivery of cargos inside the cells
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Investigation of Serine‐Proteinase‐Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI‐1)
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Errorless Learning as a method of neuropsychological rehabilitation of individuals suffering from dementia in the course of Alzheimer’s disease
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The Role of Motivation to Reduce Obesity among Elderly People: Response to Priming Temptation in Obese Individuals
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When mere multiple group memberships are not enough: Individual self-expansion through involvement in social groups and self-efficacy belief
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Simultaneous determination of individual isothiocyanates in plant samples by HPLC-DAD-MS following SPE and derivatization with N-acetyl-l-cysteine
PublicationThe procedure for the isothiocyanates (ITCs) determination that involves derivatization with N-acetyl-l-cysteine (NAC) and separation by HPLC was developed. Prior to derivatization, plant ITCs were isolated and purified using solid-phase extraction (SPE). The optimum conditions of derivatization are: 500 μL of isopropanolic eluate obtained by SPE combined with 500 μL of derivatizing reagent (0.2 M NAC and 0.2 M NaHCO3 in water)...
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Peptide splicing in a double‐sequence analogue of trypsin inhibitor SFTI‐1 substituted in the P1 positions by peptoid monomers
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Application of adjusted subpixel method (ASM) in HRCT measurements of the bronchi in bronchial asthma patients and healthy individuals
PublicationBackground: Recently, we described a model system which included corrections of high-resolution computedtomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM).Objective: To verify the clinical application of ASM by comparing bronchial measurements obtained bymeans of the traditional eye-driven method, subpixel method alone and ASM in a group comprised ofbronchial asthma patients and healthy individuals.Methods:...
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Exercise-dependent BDNF as a Modulatory Factor for the Executive Processing of Individuals in Course of Cognitive Decline. A Systematic Review
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TNFA expression level changes observed in response to the Wingate Anaerobic Test in non-trained and trained individuals
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The Effect of the Body Mass Indexes of Young Healthy Individuals on the Glyacemic Indexes of Traditional and Modified Vegetarian Meals
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Frequency and Nuisance Level of Adverse Events in Individuals Receiving Homologous and Heterologous COVID-19 Booster Vaccine
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Remote Work Support Needs of Employees with Autism Spectrum Disorder in Poland: Perspectives of Individuals with Autism and Their Coworkers
PublicationBackground and Aims: With remote work becoming more common across industries, employees with autism may experience different work support needs from neurotypical peers. However, the specific remote work needs of this group of employees are underexplored in the literature. We aim to propose ways to assess workplace digital adaptation needs for individuals with autism and a framework for communicating these needs to employers. Methods:...
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Influence of COVID-19 on lifestyle behaviors in the Middle East and North Africa Region: a survey of 5896 individuals
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Short clinically-based prediction model to forecast transition to psychosis in individuals at clinical high risk state
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Arterial stiffness increases in response to an acute arterial load challenge induced by an isometric handgrip in healthy individuals
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Evaluation of the Combination of Muscle Energy Technique and Trigger Point Therapy in Asymptomatic Individuals with a Latent Trigger Point
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Inhibitory activity of double‐sequence analogues of trypsin inhibitor SFTI‐1 from sunflower seeds: an example of peptide splicing
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Hybrid analogues of SFTI-1 modified in P1 position by β- and γ-amino acids and N-substituted β-alanines
PublicationA series of compounds containing either non-proteinogenic beta-/gamma-amino acids or N-substituted beta-alanine residues (beta-peptoid units) in P-1 specificity position were synthesized based on the structure of sunflower trypsin inhibitor 1 (SFTI-1). The compounds were synthesized on a solid support; the N-substituted beta-alanines (beta Nhlys and beta Nhphe) were introduced into a peptidomimetic chain via a two-step approach...
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Introduction of Pro and Its Analogues in the Conserved P1 Position of Trypsin Inhibitor SFTI-1 Retains Its Inhibitory Activity
PublicationA number of monocyclic SFTI-1 analogues modified in the conserved inhibitor P1 position by Pro, its L-hydroxyproline (Hyp) derivative as well as mimetics with different ring size were synthesized by the solid-phase method. Replacement of Ser6 by Pro, Hyp, and a four-member ring, L-azetidine-2-carboxylic acid (Aze), retained trypsin or chymotrypsin inhibitory activity. The determined association equilibrium constants of these analogues...
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The Beneficial Role of Involvement in Alcoholics Anonymous for Existential and Subjective Well-Being of Alcohol-Dependent Individuals? The Model Verification
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The Camberwell Assessment of Need for the Elderly questionnaire as a tool for the assessment of needs in elderly individuals living in long-term care institutions
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APPLICATION OF ENTROPY-BASED METHODS TO DISTINGUISH HEALTHY INDIVIDUALS WITH NORMAL SINUS RHYTHM FROM PATIENTS WITH CONGESTIVE HEART FAILURE
PublicationIn this paper, we examined whether entropy-based methods are able to differentiate healthy individuals from patients with congestive heart failure. To this aim, we applied two methods: Permutation Entropy and Block Entropy. Long-term ECG recordings (75 000 RR intervals) were analyzed. The results proved that both methods can distinguish those groups on condition that the parameters are appropriately chosen.
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Cross-linking of sodium caseinate-structured emulsion with transglutaminase alters postprandial metabolic and appetite responses in healthy young individuals
PublicationThe physico-chemical and interfacial properties of fat emulsions influence lipid digestion and may affect postprandial responses. The aim of the present study was to determine the effects of the modification of the interfacial layer of a fat emulsion by cross-linking on postprandial metabolic and appetite responses. A total of fifteen healthy individuals (26·5 (sem 6·9) years and BMI 21·9 (sem 2·0) kg/m2) participated in a cross-over...
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Selection of peptomeric inhibitors of bovine α-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach
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Analogues of trypsin inhibitor SFTI-1 modified in the conserved P1′ position by synthetic or non-proteinogenic amino acids retain their inhibitory activity
PublicationA series of linear and monocyclic (with a disulfide bridge only) analogues of trypsin inhibitor SFTI-1 modified in the P-1 and/or P-1' positions were synthesized by the solid-phase method. In the substrate specificity P-1 position, Phe or N-benzylglycine (Nphe) were introduced, whereas the conserved Ser6 in Bownam-Birk (BBI) inhibitors was replaced by Hse (L-homoserine), Nhse [N-(2-hydroxyethyl)glycine], Sar, and Ala. Kinetic studies...
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Changes in the EPA and DHA content and lipids quality parameters of rainbow trout (Oncorhynchus mykiss, Walbaum) and carp (Cyprinus carpio, L.) at individual stages of hot smoking
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Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors
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Hostility bias or sadness bias in excluded individuals: Does anodal transcranial direct current stimulation of right VLPFC vs. left DLPFC have a mitigating effect?
PublicationExclusion has multiple adverse effects on individual’s well-being. It induces anger and hostile cognitions leading to aggressive behavior. The purpose of this study was to test whether exclusion would affect recognition of anger on ambivalent faces of the excluders. We hypothesized that exclusion would elicit more anger encoding (hostility bias) than inclusion, but this effect would be mitigated by anodal tDCS of right VLPFC...
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New Molecular Markers Involved in Regulation of Ovarian Granulosa Cell Morphogenesis, Development and Differentiation during Short-Term Primary In Vitro Culture—Transcriptomic and Histochemical Study Based on Ovaries and Individual Separated Follicles
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Spiritual experiences as a mediator between faith as well as religious practices and hope among sex addicted individuals from Poland participating in Sex and Love Addicts Anonymous (SLAA)
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Rtęć w rozwoju osobniczym kormorana czarnego i jej biomagnifikacja w odniesieniu do ryb w ekosystemie Zalewu Wiślanego = Mercury in the individual development of Great Cormorants and its biomagnification in relation birds- fish in the Vistula Lagoon
PublicationRtęć jest pierwiastkiem, który wykazuje zdolność do kumulacji w glebie, roślinach i organizmach zwierzęcych. Jej związki charakteryzują się zróżnicowanymi właściwościami chemicznymi i fizycznymi, włączane są w różnego rodzaju cykle przyrodnicze. Bardzo szkodliwe sa pary rtęci dostające się do organizmów poprzez drogi oddechowe. Substancje toksyczne mogą zostać również wchłonięte wraz z treścią pokarmową i poprzez krew rozprowadzane...
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Individual contributions of M X-ray line from Cu- and Co-like tungsten ions and L X-ray line from Ne-like molybdenum ions – Benchmarks for new approach to determine the high-temperature tokamak plasma parameters
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POSITIVE PSYCHOLOGICAL CAPITAL ENHANCES THRIVING IN THE MULTICULTURAL WORK ENVIRONMENT OF MULTINATIONAL CORPORATIONS
PublicationThe aim of the paper is to examine positive psychological capital (PsyCap) as well as individual factors in the relationship with thriving in the multicultural work environment of multinational corporations (MNCs). We conducted a quantitative study on the sample of 127 individuals from subsidiaries of various MNCs located in Poland and involved in intercultural interactions. The results of cross-sectional study show that employees...
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Electrode-based floating treatment wetlands: Insights into design operation factors influencing bioenergy generation and treatment performance
PublicationExponential increases in energy consumption and wastewater have often irreversible environmental impacts. As a result, bio-electrochemical devices like microbial fuel cells (MFCs), which convert chemical energy in organic matter to electricity using exoelectrogenic bacteria, have gained interest. However, operational factors affecting efficiency and energy output need further study. This research investigated bioenergy production...
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A Population-Based Method with Selection of a Search Operator
PublicationThis paper presents a method based on a population in which the parameters of individuals can be processed by operators from various population-based algorithms. The mechanism of selecting operators is based on the introduction of an additional binary parameters vector located in each individual, on the basis of which it is decided which operators are to be used to modify individuals’ parameters. Thus, in the proposed approach,...
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Solving highly-dimensional multi-objective optimization problems by means of genetic gender
PublicationPaper presents a computational optimization study using a genetic gender approach for solving multi-objective optimization problems of detection observers. In this methodology the information about an individual gender of all the considered solutions is applied for the purpose of making distinction between different groups of objectives. This information is drawn out of the fitness of individuals and applied during a current parental...
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Solving highly-dimensional multi-objective optimization problems by means of genetic gender
PublicationPaper presents a computational optimization study using a genetic gender approach for solving multi-objective optimization problems of detection observers. In this methodology the information about an individual gender of all the considered solutions is applied for the purpose of making distinction between different groups of objectives. This information is drawn out of the fitness of individuals and applied during a current parental...
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Gender approach to multi-objective optimization of detection systems by pre-selection of criteria
PublicationA novel idea of performing evolutionary computations for solving highly-dimensional multi-objective optimization (MOO) problems is proposed. The information about individual genders is applied. This information is drawn out of the fitness of individuals and applied during the parental crossover in the evolutionary multi-objective optimization (EMO) processes. The paper introduces the principles of the genetic-gender approach (GGA)...
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Gender approach to multi-objective optimization of detection systems by pre-selection of criteria
PublicationA novel idea of performing evolutionary computations for solving highly-dimensional multi-objective optimization (MOO) problems is proposed. The information about individual genders is applied. This information is drawn out of the fitness of individuals and applied during the parental crossover in the evolutionary multi-objective optimization (EMO) processes. The paper introduces the principles of the genetic-gender approach (GGA)...
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Gender approach to multi-objective optimization of detection systems by pre-selection of criteria
PublicationA novel idea of performing evolutionary computations for solving highly-dimensional multi-objective optimization (MOO) problems is proposed. The information about individual genders is applied. This information is drawn out of the fitness of individuals and applied during the parental crossover in the evolutionary multi-objective optimization (EMO) processes. The paper introduces the principles of the genetic-gender approach (GGA)...