Filters
total: 674
filtered: 650
Search results for: ANTIOXIDANT PEPTIDES
-
In Vitro Antiproliferative and Antioxidant Effects of Extracts from Rubus caesius Leaves and Their Quality Evaluation
Publication -
Determination of phytochemical composition and antioxidant capacity of 22 old apple cultivars grown in Poland
Publication -
Identification of antioxidant polyphenolics from Jasione montana based on a preliminary LC-MS profiling
Publication -
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells
Publication -
Variability of Hordeum vulgare L. Cultivars in Yield, Antioxidant Potential, and Cholinesterase Inhibitory Activity
Publication -
Characteristic of antioxidant activity of dry-cured pork loins inoculated with probiotic strains of LAB
Publication -
Role of Litsea cubeba Essential Oil in Agricultural Products Safety: Antioxidant and Antimicrobial Applications
Publication -
Antimicrobial and antioxidant activities of Cinnamomum cassia essential oil and its application in food preservation
Publication -
Analysis of antioxidant capacity and polyphenol content of Goji fruit products available on the European market
Publication -
Ginsenoside and phenolic compounds in hydromethanolic extracts of American ginseng cell cultures and their antioxidant properties
Publication -
Lobularia libyca: Phytochemical Profiling, Antioxidant and Antimicrobial Activity Using In Vitro and In Silico Studies
Publication -
An In Vitro Antimicrobial, Anticancer and Antioxidant Activity of N–[(2–Arylmethylthio)phenylsulfonyl]cinnamamide Derivatives
Publication -
Selenium and mercury concentrations, Se:Hg molar ratios and their effect on the antioxidant system in wild mammals
Publication -
Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients
Publication -
Sperm Antioxidant Biomarkers and Their Correlation with Clinical Condition and Lifestyle with Regard to Male Reproductive Potential
Publication -
Mineral Composition and Antioxidant Potential in the Common Poppy (Papaver rhoeas L.) Petal Infusions
Publication -
Chemical Composition and Antioxidant Properties of Powders Obtained from Different Plum Juice Formulations
Publication -
EDS1-Dependent Cell Death and the Antioxidant System in Arabidopsis Leaves is Deregulated by the Mammalian Bax
Publication -
Comparison of bioactive compounds, antioxidant and antiproliferative activities of Mon Thong durian during ripening
PublicationCelem przeprowadzonych badań było oszacowanie zmian zawartości związków odżywczych, związków bioaktywnych, kwasów tłuszczowych oraz przeciwutleniaczy w owocach duriana w trakcie różnych etapów procesu dojrzewania. W badaniach wykorzystano testy CURRAC, DPPH, ABTS i FRAP. Stwierdzono, że całkowita zawartość polifenoli, flawonoidów, kwasu askorbimowego, tanin oraz poziom aktywności przeciwutleniającej jest dla owoców niedojrzałych,...
-
Structural, physico-chemical and antioxidant characteristics of 2,2′-bipyridyl(iminodiacetato)oxidovanadium(IV) dihydrate
Publication -
The effect of convective heating and microwave heating on antioxidant enzymes in pooled mature human milk
PublicationThe effects of convective and microwave heating at constant temperature (62.5, 66 and 70 °C) on the activity of antioxidant enzymes (superoxide dismutase, SOD; catalase, CAT; glutathione peroxidase, GPx) in pooled mature human milk were compared. Activities of the enzymes were determined using spectrophotometric kits. Activity of GPx decreased significantly in the first stage of heating when milk samples were warmed to pasteurisation...
-
Assessment of Lipophilicity Indices Derived from Retention Behavior of Antioxidant Compounds in RP-HPLC
PublicationReverse phase high pressure liquid chromatography was employed in order to evaluate the lipophilicity of antioxidant compounds from different classes, such as phenolic acids, flavanones, flavanols, flavones, anthocyanins, stilbenes, xantonoids, and proanthocyanidins. The retention time of each compound was measured using five different HPLC columns: RP18 (LiChroCART, Purosphere RP-18e), C8 (Zorbax, Eclipse XDBC8), C16-Amide (Discovery...
-
PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke
PublicationIschemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...
-
Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes
PublicationSelf-assembling peptides can be used for the regeneration of severely damaged skin. They can act as scaffolds for skin cells and as a reservoir of active compounds, to accelerate scarless wound healing. To overcome repeated administration of peptides which accelerate healing, we report development of three new peptide biomaterials based on the RADA16-I hydrogel functionalized with a sequence (AAPV) cleaved by human neutrophil elastase...
-
Tissue fixed with formalin and processed without paraffin embedding is suitable for imaging of both peptides and lipids by MALDI-IMS
Publication -
Taste-active peptides and amino acids of pork meat as components of dry-cured meat products: An in-silico study
Publication -
Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds
Publication -
Rapid PD-L1 detection in tumors with PET using a highly specific peptide
Publication -
Imunofan - RDKVYR peptide - stimulates skin cell proliferation and promotes tissue repair
PublicationRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical...
-
The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative
PublicationAcridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely analysed in antimicrobial therapy, although bioactive peptides could be used as nanocarriers to smuggle antimicrobial compounds. An octaarginine conjugate of an imidazoacridinone derivative (Compound 1-R8) synthetized by us exhibited high antifungal activity against reference...
-
A Novel Cryptic Clostridial Peptide That Kills Bacteria by a Cell Membrane Permeabilization Mechanism
PublicationThis work reports detailed characteristics of the antimicrobial peptide Intestinalin (P30), which is derived from the LysC enzyme of Clostridium intestinale strain URNW. The peptide shows a broader antibacterial spectrum than the parental enzyme, showing potent antimicrobial activity against clinical strains of Gram-positive staphylococci and Gram-negative pathogens and causing between 3.04 ± 0.12 log kill for Pseudomonas aeruginosa...
-
Imunofan—RDKVYR Peptide—Stimulates Skin Cell Proliferation and Promotes Tissue Repair
PublicationRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today’s science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical specialties. In this study, we...
-
Cyclic Peptidic Furin Inhibitors Developed by Combinatorial Chemistry
Publication -
Biological activity of conjugates of muramyl dipeptides with batracylin derivatives
PublicationW artykule opisano aktywność biologiczną koniugatów muramylo-dipeptydów z batracyliną lub pochodnymi batracyliny. Badania przeprowadzone w Akademii Medycznej w Gdańsku miały na celu oznaczenie immunomodulacyjnych właściwości tych koniugatów wobec subpopulacji leukocytów krwi obwodowej hodowanych w obecności komórek nowotworowych (K562, WEHI164, Ab melanoma). Leukocyty izolowane były z krwi obwodowej uzyskanej od zdrowych ochotników....
-
Biological activity of conjugates of muramyl dipeptides with batracylin derivatives
PublicationZaprezentowano immunomodulacyjne właściwości nowych koniugatów batracyliny (BAT) z pochodnymi muramylodipeptydów wobec subpopulacji leukocytów krwi obwodowej hodowanych w obecności komórek linii nowotworowych. Leukocyty izolowane były z krwi obwodowej uzyskanej od zdrowych ochotników. Zbadane koniugaty MDP lub nor-MDP z batracyliną wykazały silniejsze własności hamujące proliferację komórek wybranych linii nowotworowych (K562,...
-
Identification of Polyphenols from Coniferous Shoots as Natural Antioxidants and Antimicrobial Compounds
Publication -
EFFECT OF ANTIOXIDANTS ON THE STABILITY OF PITCH- BASED POLYMER TO THERMO-OXIDATIVE ACTION
PublicationThe influence of stabilizers – hydrogen donors – on the processes of thermooxidative destruction of pitch-based polymer has been investigated. It is shown that Irganox has not stabilizing effect on pitch-based polymer and melamine slightly retards the destructive process. A mixture of melamine and Irganox exhibits synergetic stabilizing effect and at the optimum ratio it can be used to prevent unwanted thermooxidative processes...
-
Antibacterial and antioxidant activity of the secondary metabolites from in vitro cultures of alice sundew (drosera aliciae)
PublicationRośliny owadożerne (D. aliciae) produkują metabolity wtórne, farmakologicznie czynne substancje. Na wzrost akumulacji tychże substancji w tkankach roślin owadożernych ma wpływ dodatek elicytora. W pracy przedstawiono zarówno optymalizacje warunków hodowli roślin, jak również prawdopodobne mechanizmy działania bakteriobójczego. Końcowego oznaczenia zawartości metabolitów w ekstraktach roślinnych dokonano techniką chromatografii...
-
In Vitro Screening for Anti-Acetylcholinesterase and Antioxidant Activities of Hottonia palustris L. Extracts and Their Unusual Flavonoids
Publication -
Comparison of Antioxidant Activity of Protein Isolates Derived from Selected Dry-Cured Meat Products
Publication -
PARTIAL WHEAT FLOUR REPLACEMENT WITH GLUTEN-FREE FLOURS IN BREAD - QUALITY, TEXTURE AND ANTIOXIDANT ACTIVITY
Publication -
Thermal processing of pasta enriched with black locust flowers affect quality, phenolics, and antioxidant activity
Publication -
The Antioxidant Properties of Selected Varieties of Pumpkin Fortified with Iodine in the Form of Potassium Iodide and Potassium Iodate
Publication -
Biosynthesis of zinc oxide nanoparticles with antimicrobial, anticancer, antioxidant and photocatalytic activities by the endophytic Alternaria tenuissima
Publication -
The Physicochemical, Antioxidant, and Color Properties of Thin Films Based on Chitosan Modified by Different Phenolic Acids
Publication -
Uncertainty of antioxidant profiling in complex mixtures using liquid chromatography involving post-column derivatisation
PublicationThe main goal of this paper is to discuss the problems associated with antioxidant profiling in complex samples using a high-throughput HPLC system coupled with post-column derivatisation reactor. Based on the experimental data reported in the literature, we demonstrated that improper optimisation of temperature and/or pH assay conditions performed using an on-line derivatisation reactor may substantially change the antioxidant...
-
LC–MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes
PublicationGalanga (Alpinia officinarum Hance) is a pungent and aromatic rhizome, which is a member of the ginger family (Zingiberaceae). The rhizomes of this plant have been used as a traditional medicine in far east countries for relieving stomach ache, invigorating the circulatory system, treating colds, and reducing swelling. The aim of this study was to investigate antioxidant and anticholinergic properties of galanga. For this purpose,...
-
Chemical composition, antioxidant and anticancer effects of the seeds and leaves and indigo (polygonum tinctorium Ait.) Plant
PublicationSeeds and leaves of indigo (Polygonum tinctorium Ait.) plant were investigated and compared with another medicinal plant named prolipid for their properties such as chemical composition, antioxidant, and anticancer effects by Fourier transform infrared, three-dimensional fluorescence spectroscopy, and electrospray ionization-MS in negative mode. It was found that polyphenols, flavonoids, and flavanols were significantly higher...
-
Interactions between bioactive components determine antioxidant, cytotoxic and nutrigenomic activity of cocoa powder extract
PublicationNumerous studies have shown, rather disappointingly, that isolated bioactive phytochemicals are not as biologically effective as natural plant products. Such a discrepancy may be explained by the concept of food synergy, which was verified in this research for cocoa extract versus its major components with regard to cancer chemoprevention. The evaluation embraced the relationship between redox properties evaluated in cell-free systems...
-
Activity of antimicrobial peptides and conventional antibiotics against superantigen positive Staphylococcus aureus isolated from patients with atopic dermatitis
Publication