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Search results for: COPPER PEPTIDES
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Design of novel microstrip directional coupler for differential signal decoupling
PublicationThis study describes a concept of a novel microstrip directional coupler for differential signal decoupling, which can be used to digital signal overhearing on printed-circuit-boards. The complete design method is proposed with rules given analytically. Considered methodology is suitable for synthesis of couplers with low coupling factors, which have negligible influence on the transmission in main line. Theoretical considerations...
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A CMRC-based compact rat-race coupler with harmonic suppression
PublicationIn this paper, an eective miniaturization technique exploiting compact microstrip resonant cells has been discussed and experimentally validated on the basis of a 3-dB microstrip rat-race coupler. The application of the method proposed has resulted in 91 % circuit area reduction in comparison to a conventional rat-race coupler. Experimental results show good agreement with theoretical characteristics, as well as an additional eect,...
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The Doppler effect in a bistatic system for determining the position of moving targets
PublicationThe article presents the theoretical analysis and the results of numerical calculations of the Doppler effect it occurs in a system designed to determine the position and speed of a moving target. The transmitter is the source of the signal and it emits a sinusoidal, acoustic and continuous wave. Signal reflected off a moving target is received by four hydrophones. Based on the signals, four Doppler shifts are determined and inserted...
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A robust design of a numerically demanding compact rat-race coupler
PublicationA fast and accurate design procedure of a computationally expensive microwave circuit has been presented step-by-step and experimentally validated on the basis of a compact rat-race coupler (RRC) comprising slow-wave resonant structures (SWRSs). The final compact RRC solution has been obtained by means of a sequential optimization scheme exploiting the implicit space mapping (ISM) algorithm. A well-suited surrogate optimization...
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Receiver of Doppler multistatic system for moving target detection and tracking
PublicationThe article presents a method for solving major structural problems that occur in the receiver used in the multistatic Doppler system, aimed at determination of the trajectory and velocity of a moving target. In the system two transmitters emit acoustic continuous sinusoidal waves at different frequencies. The signals, scattered from a moving target are received by four hydrophones. Beside of the echoes, much larger signals coming...
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Miniaturized dual‐band branch‐line coupler with enhanced bandwidth
PublicationIn this letter, a miniaturized hybrid dual-band branch-line coupler (BLC) with enhanced fractional bandwidths is proposed. Compact size and bandwidth enhancement are obtained using meandered transmission line sections with broken symmetry between cross-coupling branches. The circuit is designed at a low numerical cost using surrogate-assisted techniques. The optimized design features small size of only 0.25λg×0.19λg(28% miniaturization...
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Wideband Highly-Selective Bandpass Filtering Branch-Line Coupler
PublicationThis paper presents a novel design of a wideband highly-selective bandpass filtering branch-line coupler (FBLC). By integrating a coupled microstrip line, and an open-ended stub at each port of a single-section BLC, bandpass filtering characteristics with excellent selectivity and broad operating bandwidth have been achieved. The proposed circuit has been verified through EM simulations and physical measurements of the fabricated...
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Modelling of planar movement dynamics of upper limb
PublicationThe original model describing planar movement dynamics of upper limb is presented. The upper limb is modelled as two-joints system loaded by external forces and internal forces of striated skeletal muscles. A behaviour of each muscle is modelled as a system composed of serially linked rheologic fragments that have different mechanical properties. These muscle models allow us to simulate a behaviour of short fusiform muscle (3DOF...
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Bounds on the Cover Time of Parallel Rotor Walks
PublicationThe rotor-router mechanism was introduced as a deterministic alternative to the random walk in undirected graphs. In this model, a set of k identical walkers is deployed in parallel, starting from a chosen subset of nodes, and moving around the graph in synchronous steps. During the process, each node maintains a cyclic ordering of its outgoing arcs, and successively propagates walkers which visit it along its outgoing arcs in...
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Bounds on the cover time of parallel rotor walks
PublicationThe rotor-router mechanism was introduced as a deterministic alternative to the random walk in undirected graphs. In this model, a set of k identical walkers is deployed in parallel, starting from a chosen subset of nodes, and moving around the graph in synchronous steps. During the process, each node successively propagates walkers visiting it along its outgoing arcs in round-robin fashion, according to a fixed ordering. We consider...
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Crystal structure, DFT-study and NLO properties of the novel copper(I) nitrate π,σ-coordination compound based on 1-allyl-3-norbornan-thiourea
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The molecular function of kallikrein‐related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer
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Synthesis and SAR Studies of Antibacterial Peptidyl Derivatives Based upon the Binding Site of Human Cystatin C
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Peptydowe koniugaty antrachinonów i ich aktywność biologiczna = Peptidyl anthraquinone conjugates and its biological activity
PublicationW artykule opisano syntezę i aktywność biologiczną peptydowych koniugatów antrachinonów. Koniugaty takie są nie tylko potencjalnymi chemoterapeutykami, ale także odgrywają rolę barwnych ligandów w metodach oczyszczania białek, technikach histochemicznych i badaniu helikalnej struktury DNA z zastosowaniem spektroskopii UV i UV-Vis.
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Probing the binding selected metal ions and biologically active substances to the antimicrobial peptide LL-37 using DSC, ITC measurements and calculations
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The influence of a synthetic growth hormone‐releasing hormone analogue G11 and opioid peptide biphalin on selected fibroblasts parameters relevant to wound healing
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Comparison of peptide cancer signatures identified by mass spectrometry in serum of patients with head and neck, lung and colorectal cancers: Association with tumor progression
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Electrochemical detection of bacterial endotoxin lipopolysaccharide (LPS) on gold electrode modified with DAL-PEG-DK5-PEG-OH - Antimicrobial peptide conjugate
PublicationThis work describes fabrication of gold electrodes modified with peptide conjugate DAL-PEG-DK5-PEG-OH that enables ultra-sensitive detection of lipopolysaccharide (LPS) isolated from the reference strain of Escherichia coli O26:B6. The initial step of the established procedure implies immobilization of the fully protected DAL-PEG-DK5-PEG-OH peptide on the surface of the gold electrode previously modified by cysteamine. Then side...
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Characteristics of silver-dopped carbon nanotube coating destined for medical applications
PublicationCarbon nanotubes are materials demonstrating outstanding mechanical, chemical, and physical properties and are considered coatings of titanium implants. The present research is aimed to characterize the microstructure and properties of the multi-wall carbon nanotubes (MWCNTs) layer decorated with silver nanoparticles (Ag NPs) on the Ti13Nb13Zr alloy destined for long-term implants. The electrophoretic deposition of coatings...
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Improvement of Fingerprinting Method based on Hill Cipher by using Frequency Domain
PublicationThe main goal of this paper is to present the advantages of a digital fingerprinting in a frequency domain over a pixel domain, in case of VoD services (Video on Demand). The paper presents basic issues of a multimedia data protection by digital fingerprinting. It also describes threats to embedded fingerprints from both collusion attacks and from a transmission itself. Possible solution was presented on the example of the DCT...
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A New Coupler Concept for Contactless High-Speed Data Transmission Monitoring
PublicationThis paper presents a new concept of a couplerthat can be applied to high-speed data transmission contactlessmeasurements. The proposed approach is dedicated for differentialsignal transmission monitoring in microstrip coupled lineson printed circuit boards (PCBs). The coupler, produced on aseparate PCB, is overlayed on the transmission line with thedifferential signal and delivers decoupled differential signal tothe main measurement...
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A compact microstrip rat-race coupler constituted by nonuniform transmission lines
PublicationIn this work, a step-by-step development of a compact microstrip rat-race coupler (RRC) has been presented and discussed. A high degree of miniaturization has been obtained by substituting six quarter-wavelength uniform atomic building blocks of a RRC by their nonuniform counterparts. The miniaturization procedure has been realized in three progressive steps: (i) the first layout solution of a miniaturized RRC has been acquired...
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Novel structure and design of enhanced-bandwidth hybrid quadrature patch coupler
PublicationA novel structure and design optimization procedure of an enhanced-bandwidth hybrid quadrature patch coupler is proposed. Improved performance of the circuit has been obtained by parameterizing the coupler sections using splines, which introduces additional degrees of freedom. Due to computational complexity of the parameter adjustment problem, a sequential design procedure is applied. In each iteration, a selected number of spline...
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Underwater Navigation Ssystem Based on Doppler Shift – Measurements and Error Estimations
PublicationA new acoustic navigation system was developed to determine the position and speed of moving underwater objects such as divers and underwater vehicles. The path of an object and its speed were determined by the Doppler shifts of acoustic signals emitted by a transmitter placed on the object and received by four hydrophones installed at the periphery of the monitored body of water. The position and speed measurements were affected...
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Experimental and computational study on mechanical behaviour of carpentry corner log joints
PublicationThis work concerns experimental and numerical research on carpentry joints used in historic wooden buildings in southeastern Poland and western Ukraine. These structures are mainly sacred buildings, and the types of corner log joints characteristic of this region are primarily saddle-notch and dovetail joints; thus, these two types of joints were analysed in this study. The modelling of historic timber structures is a complex...
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Ruddlesden-Popper-type Nd2-xNi1-yCuyO4±δ layered oxides as candidate materials for MIEC-type ceramic membranes
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INFLUENCE OF DREDGER POWER PLANT TYPE AND DREDGER SIZE ON OUTPUT OF POWER PLANT INSTALLED ON TRAILING SUCTION HOPPER DREDGER
PublicationThis paper presents results of investigations dealing with influence of parameters characterizing size of suction hopper dredger as well as type of power system on magnitude of total output of combustion engines installed in dredger power plant.
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The X-ray crystallographic structures, spectral and magnetic properties of nickel(II), copper(II) and cobalt(II) complexes with tetra(3-iso-propylpyrazol-1-yl)borate
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Interference-Free Determination of Trace Copper in Freshly Ripened Honeys by Flame Atomic Absorption Spectrometry Following a Preconcentration by Solid-Phase Extraction and a Two-Step Elution Process
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Adsorption behavior and corrosion inhibitive characteristics of newly synthesized cyano-benzylidene xanthenes on copper/sodium hydroxide interface: Electrochemical, X-ray photoelectron spectroscopy and theoretical studies
PublicationElegant process for synthesis of 3-(7H-dibenzo[c,h]xanthen-7-yl)benzaldehyde (3), as new starting material to create a set of novel xanthene analogues, 2-(3-(7H-dibenzo[c,h]xanthen-7-yl)benzylidene)malononitrile (4), 3-(3-(7H-dibenzo[c,h]xanthen-7-yl)phenyl)-2-cyanoacrylic acid (5), and Ethyl-3-(3-(7H-dibenzo[c,h]xanthen-7-yl)phenyl)-2-cyanoacrylate (6), was achieved starting with available materials under mild conditions. Various...
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Automatic Detection of Cloud Cover over the Baltic Sea
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Snow Cover Studies: a Review on the Intensity of Human Pressure
PublicationSnow cover should be treated as a highly dynamic medium. A variety of physical and chemical processes interact to alter its chemical composition and affect the metamorphism of its individual crystals and layers; this, in turn, has a direct influence on their mutual adhesion, and ultimately on the stability of the entire snow cover. The literature data here reported provide basic information on the forms of solid precipitation,...
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The paired-domination and the upper paired-domination numbers of graphs
PublicationIn this paper we obtain the upper bound for the upper paired-domination number and we determine the extremal graphs achieving this bound. Moreover we determine the upper paired- domination number for cycles.
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The Examination of the Upper Layers of the Seabed by the Means of the Acoustic Methods
PublicationPropagation of acoustic waves in the sea, in particular in shallow sea, depends on several factors. The basic of them are source power and frequency of acoustic waves, spatial distribution inhomogeneous medium in which acoustic wave propagates, and distributions of speed of sound and density of seawater. The coastal conditions, which limit water medium from above (free surface of the sea) and from bottom (the seabed), are no less...
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On trees attaining an upper bound on the total domination number
PublicationA total dominating set of a graph G is a set D of vertices of G such that every vertex of G has a neighbor in D. The total domination number of a graph G, denoted by γ_t(G), is the minimum cardinality of a total dominating set of G. Chellali and Haynes [Total and paired-domination numbers of a tree, AKCE International Journal of Graphs and Combinatorics 1 (2004), 69-75] established the following upper bound on the total domination...
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Relationship between album cover design and music genres.
PublicationThe aim of the study is to find out whether there exists a relationship between typographic, compositional and coloristic elements of the music album cover design and music contained in the album. The research study involves basic statistical analysis of the manually extracted data coming from the worldwide album covers. The samples represent 34 different music genres, coming from nine countries from around the world. There are...
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The Arctic mutation alters helix length and type in the 11–28 β-amyloid peptide monomer—CD, NMR and MD studies in an SDS micelle
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Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin
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Peptide dendrimers as antifungal agents and carriers for potential antifungal agent—N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐ diaminopropanoic acid—synthesis and antimicrobial activity
PublicationA series of peptide dendrimers and their conjugates with antimicrobial agent FMDP (N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐diamino‐propanoic acid) were synthesized. The obtained compounds were tested for the antibacterial and antifungal activity. All novel dendrimers displayed much better activity against the tested strains than FMDP itself. Moreover, their conjugates with FMDP also exhibited antimicrobial activity. The most promising molecules...
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The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA
PublicationMatrix metalloproteinases (MMPs) are extracellular matrix degradation factors, promoting cancer progression. Hence, they could provide an enzyme-assisted delivery of doxorubicin (DOX) in cancer treatment. In the current study, the intercalation process of DOX and tetrapeptide-DOX, the product of the MMPs' cleavage of carrier-linked DOX, into dsDNA was investigated using stationary and time-resolved fluorescence spectroscopy, UV-Vis...
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New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases
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Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis)
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Magnetic hydrophobic deep eutectic solvents for orbital shaker-assisted dispersive liquid-liquid microextraction (MAGDES-OS-DLLME) - determination of nickel and copper in food and water samples by FAAS
PublicationIn this work, a cheap and widely applicable dispersive liquid-liquid microextraction (DLLME) method was developed for the extraction of Ni(II) and Cu(II) from water and food samples and analysis using flame atomic absorption spectrometry. DLLME was assisted by orbital shaker, while ferrofluid as an extractant was based on deep eutectic solvent (DES). This ferrofluid was made of hydrophobic DES (hDES), composed of lauric acid and...
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Suppression of distortions in signals received from Doppler sensor for vehicle speed measurement
PublicationDoppler sensors are commonly used for movement detection and speed measurement. However, electromagnetic interference and imperfections in sensor construction result in degradation of the signal to noise ratio. As a result, detection of signals reflected from moving objects becomes problematic. The paper proposes an algorithm for reduction of distortions and noise in the signal received from a simple, dual-channel type of a Doppler...
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Novel structure and EM-driven design of miniaturized microstrip rat-race coupler
PublicationIn this paper, a novel structure and design procedure of a miniaturized microstrip rat-race coupler (RRC) is described. Small size of the RRC is achieved by folding the transmission lines of the conventional circuit into its interior, as well as by implementation of the structure on three layers. The final size of the coupler realized for the operating frequency of 1 GHz is only 220 mm2, which gives over 95% footprint reduction...
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A compact seven-section rat-race hybrid coupler incorporating pbg cells
PublicationA conventional rat-race coupler has been doubly miniaturized: (i) characteristic impedances and electrical lengths of microstrip sections have been adequately modified as the first step of size reduction and (ii) T-shaped PBG cells have been implemented to diminish strip section length as the second step of circuit rat-race couplerminiaturization. The experimental results show good agreement with theoretical characteristics. Furthermore,...
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Comparison of Doppler Effect Estimation Methods for MFSK Transmission in Multipath Hydroacoustic Channel
PublicationUnderwater wireless communication remains a challenging topic, particularly for applications such as wreck penetration where multipath and Doppler effects are very intense. These effects are becoming even more difficult to mitigate for fast data transmission systems that utilize wideband signals. Due to the low propagation speed of acoustic wave in the water, there is a significant difference between the Doppler shift for lower...
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Historical carpentry corner log joints—Numerical analysis within stochastic framework
PublicationThe paper presents the results of numerical analysis performed on historical, traditional carpentry corner logjoints of two basic topologies: the short-corner dovetail connection and the saddle notch connection. These types of carpentry joints are commonly used in currently preserved objects of wooden architecture. All connections have been modelled in pinewood, which has been defined in the Finite Element software MSC.Marc/Mentat...
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Slow-wave resonant structures in branch-line coupler miniaturization: a case study
PublicationA case study of novel slow-wave resonant structures dedicated to efficient microstrip branch-line coupler size reduction has been presented. A compact 3-dB branch-line coupler has been designed to mimic the performance of its conventional counterpart, simultaneously demonstrating a substantial 88% surface area reduction. The vital usefulness of the approach in the process of microstrip line abbreviation has been experimentally...
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Effects of artificial lighting on bioactivity of sweet red pepper (Capsicum annuum L.)
PublicationRecent studies have shown that artificial light effectively promotes the growth and development of red peppers when light spectra, intensities and duration are controlled. Cited reports deal mostly with studies involving with the growth stages of pepper. Changes in the biochemical status of plants were not studied. Therefore, this study focuses on the changes in the content of some bioactive compounds (polyphenols, flavonoids,...