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Synthesis and antimicrobial activity of 6-sulfo-6-deoxy-D-glucosamine and its derivatives
Publication6-Sulfo-6-deoxy-D-glucosamine (GlcN6S), 6-sulfo-6-deoxy-D-glucosaminitol (ADGS) and their N-acetyl and methyl ester derivatives have been synthesized and tested as inhibitors of enzymes catalyzing reactions of the UDP-GlcNAc pathway in bacteria and yeasts. GlcN6S and ADGS at micromolar concentrations inhibited glucosamine-6-phosphate (GlcN6P) synthase of microbial origin. The former was also inhibitory towards fungal GlcN6P N-acetyl...
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Numerical Model of Surface and Quasi-Spherical Sea Noise and Its Application to Analysis of DIFAR Systems
PublicationVarious types of passive sonar systems are used to detect submarines. These activities are complex and demanding. Therefore, computer simulations are most often used at the design stage of these systems. For this reason, it is also necessary to simulate the acoustic ambient noise of the sea. The article proposes a new numerical model of surface and quasi-spherical sea noise and presents its statistical parameters. The results of...
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Lead In drinking water: Adsorption method and role of zeolitic imidazolate frameworks for its remediation: A review
PublicationDue to various characteristics properties lead(II) metal is utilized in many applications like lead ion batteries, water pipes, ammunition and paints. For this reason, concentration of lead(II) ions in water is increasing days by days which is alarming for water pollution. Water pollution is a major problem worldwide which affects biosphere badly, and causes continuous reduction of accessible sources of fresh water and ground water, available...
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Validated GC–MS method for determination of bisphenol a and its five analogues in dietary and nutritional supplements
PublicationBisphenol A (BPA) and its analogues showing structural and functional similarity to BPA are commonly applied in various industrial applications and thus are becoming ubiquitous in the environment. At the same time there is increasing scientific evidence that exposure to these chemicals may lead to adverse health effects in human and wildlife. In recent years dietary and nutritional supplements dedicated for athletes have become...
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Bifurcation of equilibrium forms of a gas column rotating with constant speed around its axis of symmetry
PublicationWe will be concerned with the problem of deformation of the lateral surface of a column that rotates with constant speed around its axis of symmetry. The column is filled by a gas and our goal is to investigate the deformation of the lateral surface depending on the pressure of the gas.
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Opioid Growth Factor and its Derivatives as Potential Non-toxic Multifunctional Anticancer and Analgesic Compounds
PublicationIn this paper, we review the structure-activity relationship of OGF and its analogues. We highlight also OGF derivatives with analgesic, immunomodulatory activity and the ability to penetrate the blood-brain barrier and may be used as safe agents enhancing chemotherapy efficacy and improving quality of life in cancer patients. The reviewed papers indicate that Met-enkephalin and its analogues are interesting candidates for the...
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Tacit knowledge acquisition & sharing, and its influence on innovations: A Polish/US cross-country study
PublicationThis study measures the relationship between tacit knowledge sharing and innovation in the Polish (n=350) and US (n=379) IT industries. Conceptually, the study identifies the potential sources of tacit knowledge development by individuals. That is, the study examines how “learning by doing” and “learning by interaction” lead to a willingness to share knowledge and, as a consequence, to support process and product/service innovation....
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The biological role of prolyl oligopeptidase and the procognitive potential of its peptidic inhibitors from food proteins
PublicationProlyl oligopeptidase (POP) is a conserved serine protease belonging to proline-specific peptidases. It has both enzymatic and non-enzymatic activity and is involved in numerous biological processes in the human body, playing a role in e.g., cellular growth and differentiation, inflammation, as well as the development of some neurodegenerative and neuropsychiatric disorders. This article describes the physiological and pathological...
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Giant Reed (Arundo donax L.) Fiber Extraction and Characterization for Its Use in Polymer Composites
PublicationThis work describes an extraction method for giant reed fibers from stems and leaves based on chemical soaking and crushing through a rolling mill. Obtained fibers, together with the shredded plant (stems + leaves), are characterized in terms of chemical composition, thermal stability, morphology, and crystallinity. Mechanical properties of fibers have also been assessed (single fiber tensile tests). The results show that the proposed...
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Knowledge management and factors influencing its implementation in small KIBS firms – evidence from Poland
PublicationPurpose – Even if the notion of knowledge management (KM) has been introduced more than three decades ago, the application of this concept in the context of small firms has still not been sufficiently explored. The relatively few contributions, however, agree on the fact that small companies do not manage knowledge the same way as their larger counterparts. In order to fill this gap, the present paper aims to the investigate the...
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A ROLE PLAYING GAME NAME GENERATOR LEARNING ITS CREATIVITY FROM ARKADIA MUD PLAYERS
PublicationThe paper proposes an approach to creative generation of new names for the purposes of Role Playing Games in fantasy realms. The generator based on an existing database of na mes is able to propose a set of new names with regard to demanded attributes, such as: length of the name, sex and race of the character, a given p hrase as the origin for the generated name as well as subjective evaluations from former users. The software...
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Studies on the orientation effect of crystallites and its application to cocrystal screening of selected pharmacologically active compounds
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Determining the true content of quercetin and its derivatives in plants employing SSDM and LC–MS analysis
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Selective determination of cocaine and its metabolite benzoylecgonine in environmental samples by newly developed sorbent materials
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Sea navigation-based Thai Canal implication: an analysis of its effect on the Vietnamese maritime industry
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Methylation of estrogen receptor 2 (ESR2) in deep paravertebral muscles and its association with idiopathic scoliosis
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RAILWAY WATER TOWERS OF WESTERN POLAND – HISTORIC NETWORKED ARCHITECTURAL RESOURCE AND ITS TYPOLOGICAL STRUCTURE
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The influence of ICT instruments on a transmission of interest rates by business entities and public authorities – A scientific comment
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Stress-related expression of the chloroplast EGY3 pseudoprotease and its possible impact on chloroplasts’ proteome composition
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Wybrane zagadnienia badawcze w zakresie radiokomunikacji na potrzeby systemów ITS w Polsce
PublicationW artykule przedstawiono Wybrane zagadnienia badawcze w zakresie radiokomunikacji na potrzeby systemów ITS w Polsce.
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Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management
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Contrast Tempo of Movement and Its Effect on Power Output and Bar Velocity During Resistance Exercise
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Computational model for simulation of lifeboat motions during its launching from ship in rough seas
PublicationW artykule przedstawiono model obliczeniowy 3 D, opisujący ruch obiektu w 6 stopniach swobody (6DoF), do symulacji ruchu jedno- lub dwuzawiesiowej łodzi ratunkowej lub ratowniczej podczas opuszczania ze statku na wzburzonej wodzie. Jest to złożony model uwzględniający warunki morskie oraz elastyczność i własności tłumiące elementów i mechanizmów żurawika, liny oraz kadłuba łodzi. Ponadto przedstawiono przykładowe wyniki obliczeń...
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Catalytic carbonization of polypropylene by the combined catalysis of activated carbon with Ni2O3 into carbon nanotubes and its mechanism
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Longitudinal tracking of muscle sympathetic nerve activity and its relationship with blood pressure in subjects with prehypertension
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Influence of Illite and Its Amine Modifications on the Self-Adhesive Properties of Silicone Pressure-Sensitive Adhesives
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Influence of diatomite and its base modifications on the self-adhesive properties of silicone pressure-sensitive adhesives
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The accumulation of metal (Co, Cr, Cu, Mn and Zn) in freshwater Ulva (Chlorophyta) and its habitat
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Does Mass Culture Mean a Crisis of Values? Dwight Macdonald's Position and the Issue of Its Topicality
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EFFECT OF CHITOSAN AND LIPID LAYERS DEPOSITED ONTO POLYETHYLENE TEREPHTHALATE (PET) ON ITS WETTING PROPERTIES
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The effect of cabbage juice and its active components on transcription factor Nrf2 in breast cell lines
PublicationObniżenie zagrożenia chorobami nowotworowymi w przypadku diety bogatej w kapustę wiąże się ze zdolnością bioaktywnych związków tego warzywa do indukowania enzymów ochronnych 2. fazy będacych pod kontrolą czynnika transkrypcyjnego Nrf2. Zbadano wpływ soków z kapusty na poziom Nrf2 w komórkach unieśmiertelnionych i nowotworowych linii odpowiednio MCF10A i MCF-7. W obu przypadkach obserwowano wzrost poziomu tego czynnika oraz jego...
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A new approach to numerical solution of fixed-point problems and its application to delay differential equations
PublicationW pracy rozpatruje się pewne aproksymacje punktu stałego ciągłego operatora A odwzorowującego przestrzeń metryczną w siebie. Wspomniany punkt stały przybliża się tzw. epsilon przybliżonym punktem stałym z przestrzeni skończenie wymiarowej. Udowodnione zostało twierdzenie dające warunki konieczne i dostateczne istnienia punktu stałego w ogólnej przestrzeni metrycznej. Warunki te wyrażone są w terminach epsilon przybliżonego punktu...
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Total Selenium Level and Its Distribution between Organs in Beef Cattle in Different Selenium Status
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Improvement of machinability of Ti and its alloys using cooling-lubrication techniques: a review and future prospect
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China’s Belt and Road Initiatives (BRI) in South Asia and Its Policy Challenges to India in the Region
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Application of a magnetically separable Zr-MOF for fast extraction of palladium before its spectrophotometric detection
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Characteristics of the Conjugative Transfer System of the IncM Plasmid pCTX-M3 and Identification of Its Putative Regulators
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Tuning of the Anti-Breast Cancer Activity of Betulinic Acid via Its Conversion to Ionic Liquids
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Investigation of the Binding Properties of the Cosmetic Peptide Argireline and Its Derivatives Towards Copper(II) Ions
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A CRISPR/Cas9-Based Mutagenesis Protocol for Brachypodium distachyon and Its Allopolyploid Relative, Brachypodium hybridum
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Metabolic activation of adriamycin by NADPH-cytochrome P450 reductase; overview of its biological and biochemical effects
PublicationOmówione zostały efekty aktywacji metabolicznej adriamycyny przez NADPH-zależną reduktazę cytochromu P450. Wykazano, że ten rodzaj aktywacji zwiększa aktywność biologiczną tego związku, a przy tym powoduje jego wiązanie się kowalencyjne z ważnymi biologicznie makromolekułami komórkowymi.
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INTRODUCING GREENERY INTO A BUILDING BASED ON ITS IMPACT ON HUMAN WELLBEING - REVIEW OF THEORIES AND METHODS IN ARCHITECTURE
PublicationGreenery around and within buildings is an integral part of architectural space. Although science is providing more and more knowledge about the impact of greenery on human well-being, there is still a lack of guidelines on how to apply this knowledge in architectural design. The purpose of this review article is to prepare the ground for further research on how to support architectural design in integrating greenery as a co-creative...
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Computational Complexity and Its Influence on Predictive Capabilities of Machine Learning Models for Concrete Mix Design
PublicationThe design of concrete mixtures is crucial in concrete technology, aiming to produce concrete that meets specific quality and performance criteria. Modern standards require not only strength but also eco-friendliness and production efficiency. Based on the Three Equation Method, conventional mix design methods involve analytical and laboratory procedures but are insufficient for contemporary concrete technology, leading to overengineering...
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Cavitation erosion behavior of 18/8 stainless steel after its laser alloying of manganese
PublicationW pracy przedstawiono badania kawitacyjne stali austenitycznej 18/8 po laserowym stopowaniu jej powierzchni różną zawartością manganu. Oceniano podatnoś stopowanej powierzchni do odkształceniowego umacniania pod wpływem obciążeń kawitacyjnych oraz głębokość umocnienia.
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Forced vibrations in a dynamic system that is damped by a mechanism that trans-pass through its singular position
PublicationIn the paper, vibrations of a hybrid multibody-continuous system are investigated. For all the mechanical devices, effective damping methods are crucial in the design process. To obtain it, installation of viscous dampers or elasto-viscous elements is dominant. In the paper, an alternative method is investigated. It is based on modal disparity. To describe the method briefly, when structural damping is present in continuous systems,...
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Metoda adaptacyjnej kompresji statycznych obrazów rastrowych i jej zastosowanie w systemach ITS
PublicationW referacie przedstawiono koncepcję i przykład zastosowania adaptacyjnej metody kompresji obrazów rastrowych, która może znaleźć zastosowanie m.in. w systemach ITS. Opracowana metoda pozwala na poprawę efektywności działania systemów zaliczanych do klasy ITS, w których istnieje konieczność transmisji bardzo dużych wolumenów danych obrazowych, za pośrednictwem sieci telekomunikacyjnych. Koncepcja opisanej w pracy adaptacyjnej metody...
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Computational simulation of motion of a rescue module during its launching from ship at rough sea
PublicationThis paper is a continuation of the work titled : “A comp utational model for simulation of motion of rescue module during its launching from stern ramp of a ship at rough sea”. It presents results of computer simulations of motion of a rescue module with embarked persons during its launching on rollers along stern ramp of a ship at rough sea. The simulations were conducted for a selected ship fitted with a launching ramp , for...
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The influence of high temperature wood drying conditions using air-steam mixture on its properties
PublicationThe results of properties change of beech wood after drying process are presented. The wood taken to experiments was from northern part of Pomeranian region in Poland. Before the main high temperature drying process using air-steam mixture, wood was initially dried in an open air conditions. The high temperature drying process was conducted at temperature 120oC, humidity 48%, flow rate of drying medium 2.5m/s and atmospheric pressure....
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Chitosan and polyvinyl alcohol nanocomposites with cellulose nanofibers from ginger rhizomes and its antimicrobial activities
PublicationThe inhibitory effect of 5% GNF bionanocomposites against Bacillus cereus, Escherichia coli, Staphylococcus aureus and Salmonella typhimurium indicated good antibacterial activity of the nanocomposites due to the addition of GNF in the biopolymer matrices. The use of GNF will help to increase the economic values of agricultural waste and the characteristic properties of GNF derived bionanocomposites could be possibly used in medical...
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General, Mild, and Metal-Free Functionalization of Indole and Its Derivatives Through Direct C3-Selenylation
PublicationA very mild method for the introduction of functionalized alkylselenyl group at C-3 position of the indole ring was developed. The proposed procedure consists of an electrophilic substitution of indole and its derivatives with bis(O,O-diisopropoxyphosphorothioyl) diselenide and subsequent cleavage of the P–Se bond with tetrabutylammonium fluoride in the presence of various electrophilic reagents. This method can be successfully...