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Search results for: SPIKE-ADDING
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Wild oscillations in a nonlinear neuron model with resets: (I) Bursting, spike-adding and chaos
PublicationIn a series of two papers, we investigate the mechanisms by which complex oscillations are generated in a class of nonlinear dynamical systems with resets modeling the voltage and adaptation of neurons. This first paper presents mathematical analysis showing that the system can support bursts of any period as a function of model parameters, and that these are organized in a period-incrementing structure. In continuous dynamical...
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Spike patterns and chaos in a map-based neuron model
PublicationThe work studies the well-known map-based model of neuronal dynamics introduced in 2007 by Courbage, Nekorkin and Vdovin, important due to various medical applications. We also review and extend some of the existing results concerning β-transformations and (expanding) Lorenz mappings. Then we apply them for deducing important properties of spike-trains generated by the CNV model and explain their implications for neuron behaviour....
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Adding Interpretability to Neural Knowledge DNA
PublicationThis paper proposes a novel approach that adds the interpretability to Neural Knowledge DNA (NK-DNA) via generating a decision tree. The NK-DNA is a promising knowledge representation approach for acquiring, storing, sharing, and reusing knowledge among machines and computing systems. We introduce the decision tree-based generative method for knowledge extraction and representation to make the NK-DNA more explainable. We examine...
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Quantitative determination of mechanical stability in the novel coronavirus spike protein
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Spikes removal in surface measurement
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Adding knowledge management perspective to business process management
PublicationPrzestawiono koncepcje integracji technologii wspomagania zarządzania wiedzą z podejściem procesowym do zarządzania organizacją. Przedstawiono koncepcje integracji oraz jej zalety.
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Adding Intelligence to Cars Using the Neural Knowledge DNA
PublicationIn this paper we propose a Neural Knowledge DNA based framework that is capable of learning from the car’s daily operation. The Neural Knowledge DNA is a novel knowledge representation and reasoning approach designed to support discovering, storing, reusing, improving, and sharing knowledge among machines and computing devices. We examine our framework for drivers' classification based on their driving behaviour. The experimental...
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A Perspective on Fast-SPICE Simulation Technology
PublicationThis chapter presents an introduction to the area of accelerated transistor-level (‘fast-SPICE’) simulation for automated verification and characterization of integrated circuits (ICs) from technologist’s perspective. It starts with outlining goals, expectations and typical usage models for fast-SPICE simulators, stressing how they differ from regular SPICE tools. It continues with presenting and classifying core technologies typically...
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Network oscillations modulate interictal epileptiform spike rate during human memory
PublicationEleven patients being evaluated with intracranial electroencephalography for medically resistant temporal lobe epilepsy participated in a visual recognition memory task. Interictal epileptiform spikes were manually marked and their rate of occurrence compared between baseline and three 2 s periods spanning a 6 s viewing period. During successful, but not unsuccessful, encoding of the images there was a significant reduction in...
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Measure small currents without adding resistive insertion loss
PublicationFloating current to voltage converter can be inserted in-line with no voltage drop and no need for a ground reference.
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Characterization of Structural and Energetic Differences between Conformations of the SARS-CoV-2 Spike Protein
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The Politics of Ageing and the Challenges of Ageing Populations
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Reactivation of seizure‐related changes to interictal spike shape and synchrony during postseizure sleep in patients
PublicationOBJECTIVE: Local field potentials (LFPs) arise from synchronous activation of millions of neurons, producing seemingly consistent waveform shapes and relative synchrony across electrodes. Interictal spikes (IISs) are LFPs associated with epilepsy that are commonly used to guide surgical resection. Recently, changes in neuronal firing patterns observed in the minutes preceding seizure onset were found to be reactivated during postseizure...
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Electrohydrodynamic flow and particle collection efficiency in a one-sided spike-plate type electrostatic precipitator
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Electrohydrodynamic Secondary Flow and Particle Collection Efficiency in Spike-Plate Multi-Electrode Electrostatic Precipitator
PublicationIn this work the results of electrohydrodynamic (EHD) secondary flowmeasurements in a spike-plate type electrostatic precipitator (ESP) are presented. In the investigated ESP two-sided and one-sided spike electrodes were used as a discharge electrodes. The results of 2D PIVmeasurements showed that flow pattern obtained for a different spike tips positions in respect to the primary flow direction significantly changing the flow...
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Pumping effect measured by PIV method in a multilayer spike electrode EHD device for air cleaning
PublicationDust particles can be harmful for human health when inhaled. Particularly dangerous are submicrometer dust particles, which can contain traces of toxic elements and can easily penetrate into the human respiratory system. Thus, efficient devices for the air cleaning from submicrometer dust particles are needed. Recently, Katatani and Mizuno have proposed an electrohydrody- namic (EHD) device for air cleaning for submicrometer particles....
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Electrohydrodynamic secondary flow and particle collection efficiency in spike-plate multi-electrode electrostatic precipitator
PublicationIn this work the results of electrohydrodynamic (EHD) secondary flow measurements in a spike-plate type electrostatic precipitator (ESP) are presented. In the investigated ESP two-sided and one-sided spike electrodes were used as a discharge electrodes. The results of 2D PIV measurements showed that flow pattern obtained for a different spike tips positions in respect to the primary flow direction significantly changing the flow...
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The Effect of Spikes Occurrence on Surface Texture Parameter Assessments
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passive spice networks from non-passive data
PublicationArtykuł przestawia technike generacji schematow zastepczych w formacie SPICE dla pasywnych układów mikrofalowych. Wynikowy schemat zastepczy ma zagwarantowana pasywnosc. Schematy zastepcze powstaja na podstawie symulacji lub pomiarow w dziedzinie czestotliwosci i moga byc wykorzystane do symulacji w dziedzinie czasu.
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Comparison of EHD devices with parallel and in series spiked electrodes
PublicationIn this paper two electrohydrodynamic (EHD) devices for gas pumping and cleaning are presented. In both cases to induce an airflow in these EHD devices corona discharge was used. The discharge was generated between the spiked electrodes set parallel (the first case) or in series (the second case) and the plate electrodes. An asymmetric electric field and generated discharge result in unidirectional gas flow through the EHD device....
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Electrohydrodynamic secondary flow in the electrostatic precipitator with spiked electrodes
PublicationIn this work, the results of electrohydrodynamic (EHD) secondary flow measurements in an electrostatic precipitator (ESP) with one-sidedspike electrodes are presented. The EHD secondary flow was measured for one-sided spike electrodes with the spike tips directed either upstream or downstream the primary flow. The results showed different flow patterns for different spike tips direction in respect to the primary flow direction....
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Development and validation of lumbar spine finite element model
PublicationThe functional biomechanics of the lumbar spine have been better understood by finite element method (FEM) simulations. However, there are still areas where the behavior of soft tissues can be better modeled or described in a different way. The purpose of this research is to develop and validate a lumbar spine section intended for biomechanical research. A FE model of the 50th percentile adult male (AM) Total Human Model for Safety...
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The effect of adding a standard on the result of determination of polychlorinated biphenyls in bottom sediment samples
PublicationBottom sediments are a very important component of aquatic ecosystems. The sediment matrix is highly diverse and heterogeneous; in consequence, compounds entering the aquatic environment from different sources are considerably enriched at its surface. Bottom sediments are regarded as natural sorbents, since they accumulate many harmful substances, such as heavy metals and stable organic contaminants.Extraction is a key stage in...
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t-SNE Highlights Phylogenetic and Temporal Patterns of SARS-CoV-2 Spike and Nucleocapsid Protein Evolution
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Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
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Pumping effect measured by PIV method in multi-layer spike electrode EHD device for air cleaning
PublicationDust particles can be harmful for human health when inhaled. Especially dangerous are submicron dust particles, which can contain traces of toxic elements and can easily penetrate into human respiratory system. Thus, new devices for air cleaning are needed. In this work the flow velocity field patterns measured by Particle Image Velocimetry (PIV) method in an electrohydrodynamic (EHD) device for air cleaning are presented. The...
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Electrohydrodynamic Secondary Flow and Particle Collection Efficiency in a One-sided Spike-plate Type Electrostatic Precipitator
PublicationIn this work, results of electrohydrodynamic secondary flow and particle collection efficiency measurements in an electrostatic precipitator under positive and negative voltage polarity are presented. The electrostatic precipitator had two plate collecting electrodes and a single spike discharge electrode. The spike tips were only on one side of the discharge electrode, therefore called a one-sided spike electrode. The electrohydrodynamic...
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Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
PublicationAn important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) host cell receptor. Therefore, to explore conserved features in spike protein dynamics and to identify potentially novel regions for drugging, we measured spike protein variability derived from 791 viral genomes and studied its properties by molecular...
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t-SNE Highlights Phylogenetic and Temporal Patterns of SARS-CoV-2 Spike and Nucleocapsid Protein Evolution
PublicationWe propose applying t-distributed stochastic neighbor embedding to protein sequences of SARS-CoV-2 to construct, visualize and study the evolutionary space of the coronavirus. The basic idea is to explore the COVID-19 evolution space by using modern manifold learning techniques applied to evolutionary distances between variants. Evolutionary distances have been calculated based on the structures of the nucleocapsid and spike proteins.
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Holistic Approach to the Diagnosis and Treatment of Patients with Tumor Metastases to the Spine
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Ginger (<i>Zingiber officinale</i>) – a spice with therapeutic properties
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Equivalent spice circuits with guaranteed passivity from nonpassive models
PublicationW artykule przedstawiona została nowa technika wymuszania pasywności schematów zastępczych. Opracowana technika pozwala na konstrukcję schematów zastępczych bardzo złożonych układów, oraz pozwala na wymuszenie pasywności modelu tworzonego na podstawie danych niepasywnych.
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A New Technique of Spine Disease Treatment Supported by ADRSK1 Device
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Multivalent Display of SARS-CoV-2 Spike (RBD Domain) of COVID-19 to Nanomaterial, Protein Ferritin Nanocages
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Gamma oscillations precede interictal epileptiform spikes in the seizure onset zone
PublicationOBJECTIVE: To investigate the generation, spectral characteristics, and potential clinical significance of brain activity preceding interictal epileptiform spike discharges (IEDs) recorded with intracranial EEG. METHODS: Seventeen adult patients with drug-resistant temporal lobe epilepsy were implanted with intracranial electrodes as part of their evaluation for epilepsy surgery. IEDs detected on clinical macro- and research microelectrodes...
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Assessment of the effectiveness of physiotherapy after surgical treatment of the cervical or lumbar spine
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Wykorzystanie modeli cmm i spice w zarządzaniu przedsięwzięciami informatycznymi
Publicationw pracy zaprezentowano problematykę planowania i oceny organizacji projektowych realizujących przedsięwzięcia informatyczne. wydaje się, bowiem, że przy realizacji przedsięwzięcia planowanie, organizowanie i kontrolowanie pracy zespołu ma 'kluczowe' znaczenie dla zakończenia przedsięwzięcia w założonym czasie i przyjętych środkach (przy określonych standardach jakości). omówiono, więc metody oceny poziomu dojrzałości zespołu a...
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A spice equivalent circuit for modeling the performance of dual frequency echo-sounder
PublicationThe paper presents novel network equivalent circuit of piezoceramic circular disc transducers that takes into account thickness and radial mode of vibrations. The starting point of the analysis is 4-port description of circular disc element representing the solution of wave equation set in radial and thickness directions. The approximate solution for harmonic case is represented in the form of 4x4 matrix, which is synthesised and...
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CaZnO-based nanoghosts for the detection of ssDNA, pCRISPR and recombinant SARS-CoV-2 spike antigen and targeted delivery of doxorubicin
PublicationOverexpression of proteins/antigens and other gene-related sequences in the bodies could lead to significant mutations and refractory diseases. Detection and identification of assorted trace concentrations of such proteins/antigens and/or gene-related sequences remain challenging, affecting different pathogens and making viruses stronger. Correspondingly, coronavirus (SARS-CoV-2) mutations/alterations and spread could lead to overexpression...
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Bending Moment Control and Weight Optimization in Space Structures by Adding Extra Members in the Optimal Locations
PublicationThis paper investigates the reduction of bending moment in critical members by adding some extra members in the optimum location. Instead of enlarging the size of members to resist the moment, eight additional members are added in the optimum location to reduce the bending moment in the critical members. The total weight of the proposed structure with extra members is less than that of the original structure that resists the induced...
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Doing well by doing good — CSR in a global context
PublicationMotivation: Nowadays, there is a general understanding that stakeholders are crucial for the successful enterprise. There is also a need to think about Corporate Social Responsibility (CSR) in a global context. Never before corporations enjoyed so much power and authority. Corporations need to evolve, re-think their strategies and change their processes accordingly. However, as of now, there is no agreed way of measuring overall...
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Creative Aging: Drawing on the Arts to Enhance Healthy Aging
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Creative Aging, Drawing on the Arts to Enhance Healthy Aging
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Doing Well by Doing Good- CSR in a Global Context
PublicationNowadays, there is a general understanding that stakeholders are crucial for the successful enterprise. There is also a need to think about Corporate Social Responsibility (CSR) in a global context. Never before corporations enjoyed so much power and authority. Corporations need to evolve, re-think their strategies and change their processes accordingly. However, as of now, there is no agreed way of measuring overall sustainability...
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Bioactive hybrid metal-organic framework (MOF)-based nanosensors for optical detection of recombinant SARS-CoV-2 spike antigen
PublicationFast, efficient, and accurate detection of SARS-CoV-2 spike antigen is pivotal to control the spread and reduce themortality of COVID-19. Nevertheless, the sensitivity of available nanobiosensors to detect recombinant SARS-CoV-2 spike antigen seems insufficient. As a proof-of-concept, MOF-5/CoNi2S4 is developed as a low-cost, safe, and bioactive hybrid nanostructure via the one-pot high-gravity protocol. Then, the porphyrin, H2TMP,...
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Aging and/with Literature
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Productive aging
PublicationThe term “productive aging” refers to the participation of older adults in different activities that contribute to generating goods and services and develop the capacity to produce goods and services. In that sense, it includes both the economic activity of this group – serving in the paid workforce – and its social productivity, understood as volunteer activities (Bass et al. 1993). In the broader sense, “productive aging” can...
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Assessment of the results of surgical treatment and postoperative physiotherapy in patients with degenerations of the cervical spine
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Biomechanics of Lumbar Spine Injury in Road Barrier Collision–Finite Element Study
PublicationLiterature and field data from CIREN database have shown that lumbar spine injuries occur during car crashes. There are multiple hypotheses regarding how they occur; however, there is no biomechanical explanation for these injuries during collisions with road safety barriers (RSBs). Therefore, the objective of this study was to investigate the mechanics of vertebral fractures during car collisions with concrete RSBs. The finite...
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Numerical analysis of lumbar spine injury during road safety barrier collision
PublicationPurpose: Enhancing road safety is a critical goal worldwide, necessitating the development of clear standards for road safety systems. This study focuses on lumbar spine (L-spine) compression injuries during collisions with concrete road safety barriers (RSBs). It aims to analyze internal forces during impact to understand L-spine injury biomechanics in such accidents. Methods: The research included a literature review, analyzing...