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Wyniki wyszukiwania dla: SUSTAINABLE DEVELOPMENT AND TAX
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Muscle Cell Morphogenesis, Structure, Development and Differentiation Processes Are Significantly Regulated during Human Ovarian Granulosa Cells In Vitro Cultivation
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Development of Physics-Based Energy Functions that Predict Medium-Resolution Structures for Proteins of the α, β, and α/β Structural Classes
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Rural Landscapes of Roman (northern) Liburnia: Diachronic Development of Organisation and the Economy in Extra-Urban Territories in the Light of Recent Archaeological Research
PublikacjaThe archaeology of Roman rural landscapes in the province of Dalmatia, and especially northern Liburnia, has until recently focused on single-site or single-monument analyses, allowing for only geographically patchy and chronologically limited conclusions. Considering the results of recent research in the wider Kvarner and sub-Velebit area, the paper discusses issues of Roman extra-urban territorial organization, the formation...
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Development of different methods for drugs and psychoactive substances extraction from hair samples and their identification based on HPLC-ESI-QTOF analysis
PublikacjaOver the past decade, the use of non-controlled designer drugs and drug of abuse has rapidly increased. Hair, as a human matrix, enables detection of drugs incorporated into its structure. Studies of presence and identification of drug metabolites in human hair samples has been performed using liquid chromatography electrospray ionization quadrupole time of flight mass spectrometry (HPLC-ESI-QTOF-MS) with steady alternation of...
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Development of potent and effective SARS-CoV-2 main protease inhibitors based on maleimide analogs for the potential treatment of COVID-19
PublikacjaIn the present work, we report a new series of potent SARS-CoV-2 Main Protease (Mpro) inhibitors based on maleimide derivatives. The inhibitory activities were tested in an enzymatic assay using recombinant Mpro (3CL Protease from coronavirus SARS-CoV-2). Within the set of new Mpro inhibitors, 6e demonstrated the highest activity in the enzymatic assay with an IC50 value of 8.52 ± 0.44 mM. The IC50 value for Nirmatrelvir (PF-07321332,...
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Amphotericin B derivatives: novel strategy for the development of non-toxic, broad spectrum, fungicidal and overcoming multidrug resistance antifungal agents.
PublikacjaZaprezentowano porównawczą charakterystykę działania amfoterycyny B (AmB) oraz jej pochodnych o różnym stopniu selektywnej toksyczności na szczepy grzybów reperezentujących różne mechanizmy oporności. Były to mutanty C. albicans posiadające defekt w szlaku biosyntezy ergosterolu oraz wielolekooporne szczepy S. cerevisiae wyposażone w pompy eksportujące typu ABC i MFS. Badania obejmowały: 1)porównanie aktywności przeciwgrzybowej...
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Enhancing women’s engagement in economic activities through information and communication technology deployment: evidence from Central–Eastern European countries
PublikacjaThis study takes a macro perspective to examine the associations between the economic deployment of information and communication technology (ICT), women’s labor market participation, and economic growth in Central–Eastern European countries between 1990 and 2017. We use data extracted from World Bank Development Indicators, World Development Reports, and the World Telecommunication/ICT Indicators Database. Our methodological framework...
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Universities’ journey towards sustainability- systematic literature review
PublikacjaPurpose: This research aims to identify a sustainable university's key features. It is an essential step in tracing the topics discussed in the context of a sustainable university and their evolution in the scientific discourse. Design/methodology/approach: This paper relies on a systematic literature review (SLR) conducted using two scholarly databases: Emerald and Scopus. The timeframe selected by the authors for reviewing the...
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Assessment of the Feasibility of Energy Transformation Processes in European Union Member States
PublikacjaThe energy transition is now treated in most countries as a necessary condition for their long-term development. The process of energy transformation assumes the simultaneous implementation of the Sustainable Development Goals, which are a major challenge for modern economies and introduce significant restrictions in their functioning. Our study aims to group EU member states according to their ability to achieve energy transition...
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Game about space or game in the space?
PublikacjaThe article analyzes various aspects of the actions taken by participants involved in the process of a spatial change. Such a process is described as a game about space or a game in the space. Different terminology is presented, in particular the meaning of: spatial order, regional studies, eco-development, sustainable development. Different forms of the game are analyzed: space as a theater, as a casino, as an area of conflict....
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Working in harmony with nature. Green office buildings in a present-day city
PublikacjaMetropolis - as main point of people's migration, mostly because of work, have to face sustainable development as a strategy for the near future. This article describes possible ways leading to the best office building concepts in the design process. Searching for a workspace in harmony with nature is one of the aspects of a balanced development. The challenge is to create functional, compact, environmentally friendly and healthy...
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Problem wspólnotowego kształtowania środowiska mieszkaniowego
PublikacjaCommunity based shaping of housing environmentA sustainable development of housing environment depends on socio-economical context. Interest towards locality in western countries has a completely different basis than in the post-communist ones. Social capital, which shows e.g. in trust, as well as ecological awareness are totally different. We do not belong to saturated societies. There is a distinct issue of community shaping...
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Investigating the sustainability, utilisation, consumption and conservation of sea mammals – A systematic review
PublikacjaAlmost 80 % of the oceans, especially the Arctic and Subarctic are primarily inhabited by marine mammals. Marine species depend mostly on sea ice for food, raising their young ones and safeguarding themselves from predators. Consumption of marine mammals has always been recommended as healthy, but the truth is that it can be detrimental for human health because of sea water pollution from trash and chemicals. This systematic review...
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Development of direct-current, atmospheric-pressure, glow discharges generated in contact with flowing electrolyte solutions for elemental analysis by optical emission spectrometry
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Modeling the economic dependence between town development policy and increasing energy effectiveness with neural networks. Case study: The town of Zielona Góra
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Measuring Consumers' Engagement With Brand-Related Social-Media Content. Development and Validation of a Scale that Identifies Levels of Social-Media Engagement with Brands
PublikacjaThe purpose of the current study was to develop a scale to measure the consumer's engagement with brand-related social-media content, based on three dimensions established in the framework of an earlier theoretical construct, “Consumer's Online Brand-Related Activities” (Muntinga, Moorman, and Smit, 2011). Qualitative techniques were used to generate an initial pool of items that captured different levels of consumer engagement...
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ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1) affects development, photosynthesis, and hormonal homeostasis in hybrid aspen ( Populus tremula L. × P. tremuloides )
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High-Speed Videoendoscopy Enhances the Objective Assessment of Glottic Organic Lesions: A Case-Control Study with Multivariable Data-Mining Model Development
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Evaluation of floor-wise pollution status and deposition behavior of potentially toxic elements and nanoparticles in air conditioner dust during urbanistic development
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Systolic blood pressure control prevents cognitive decline and slows development of white matter lesions in the brain: the SPRINT MIND study outcomes
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Reconstructing human impact on peatland development during the past 200 years in CE Europe through biotic proxies and X-ray tomography
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Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development
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New Gene Markers of Angiogenesis and Blood Vessels Development in Porcine Ovarian Granulosa Cells during Short-Term Primary Culture In Vitro
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Epithelium morphogenesis and oviduct development are regulated by significant increase of expression of genes after long-term in vitro primary culture – a microarray assays
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‘Heart development and morphogenesis’ is a novel pathway for human ovarian granulosa cell differentiation during long‑term in�vitro cultivation‑a microarray approach
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Harman and norharman, metabolites of entomopathogenic fungus Conidiobolus coronatus (Entomopthorales), disorganize development of Galleria mellonella (Lepidoptera) and affect serotonin-regulating enzymes
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Development of biocompatible iron oxide-silicon oxide core-shell nanoparticles as subcellular delivery platform for glucosamine-6-phosphate synthase inhibitors
PublikacjaIn order to develop the preparation of iron oxide-silica coreshell nanoparticles (CSNPs), thesis deeply explores the cetyltrimethylammonium (CTA+) directed silica coating methods of the oleic-acid capped iron oxide nanoparticles (OA-IONPs) initialized under near-neutral pH conditions. It is demonstrated that the initial alkaline hydrolysis of ethyl acetate in the presence of CTA+ and OA-IONPs induces an unusual ligand exchange...
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Fighting Administrative Corruption with Digital Government in Sub-Saharan Africa
PublikacjaAdministrative corruption is a pervasive problem and a major threat to economic and social development around the world, especially in Sub-Saharan Africa which lags behind other regions in various development indicators and is seen as one of the most corrupt regions globally. This paper examines a hypothesis that digital government – the use of digital technology to transform public administration organizations and their relationships...
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Upward convergence patterns in chosen environmental-related SDGs
PublikacjaSustainable development is a challenge facing humanity. EU countries not only strive to reach their specific objectives, but they also work collaboratively towards shared goals. There is a need to balance synergies and compromises to address these objectives effectively. When discussing countries' development and people's well-being, one often focuses on socio-economic development. However, it is crucial not to overlook the environmental...
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Knowledge Societies Policy Handbook
PublikacjaThe Handbook builds upon existing knowledge and practices to provide policy-makers with an actionable conceptual framework for understanding and assessing the relationships between the Sustainable Development Goals and Knowledge Societies. By identifying gaps as well as strengths, the Handbook will enable countries to more effectively deploy resources and implement appropriate policy measures.
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Potential applications of crude glycerol in polymer technology–Current state and perspectives
PublikacjaThe increasing use of bio-based fuels and fuel additives, among them biodiesel, causes significant surplus of crude glycerol on the market which creates new challenges in terms of its sustainable utilization. A lot of ways for the incorporation of this by-product into different branches of industry requires purification by expensive and complicated processes. Therefore, researchers are seeking for applications of untreated crude...
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Development of a vortex-assisted switchable-hydrophilicity solvent-based liquid phase microextraction for fast and reliable extraction of Zn (II), Fe (II), Pb (II), and Cd (II) from various baby food products
PublikacjaThis manuscript describes the development of a novel liquid phase microextraction (LPME) method for the extraction and determination of Zn (II), Fe (II), Pb (II), and Cd (II) in various infant/baby food and supplements products. The method is based on vortex-assisted extraction combined with a switchable-hydrophilicity solvent (SHS) sample preparation. The SHS, which undergoes reversible phase changes triggered by pH change, enables...
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Trends in Automotive Emission Legislation: Impact on LD Engine Development, Fuels, Lubricants and Test Methods: a Global View, with a Focus on WLTP and RDE Regulations
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Viral infection-oxidative stress/DNA damage-aberrant DNA methylation: separate or interrelated events responsible for genetic instability and childhood ALL development?
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GIS Technology, 3D Models and Mathematical Models as a Tool for Assessing Development Capabilities of Flood Risk Land to Make Arrangements of Municipal Planning Documents
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The Role of GLP-1, GIP, MCP-1 and IGFBP-7 Biomarkers in the Development of Metabolic Disorders: A Review and Predictive Analysis in the Context of Diabetes and Obesity
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Method development and validation for optimized separation of quercetin derivatives in selected Potentilla species using high-performance thin-layer chromatography photodensitometry method
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Development of a new green analytical methodology for the determination of phthalates in single-use babies diapers using ultrasound-assisted extraction and polypropylene porous membrane
PublikacjaA green extraction strategy was developed and utilized for the extraction and determination of phthalates. The extraction is based on ultrasound-assisted extraction and a polypropylene porous membrane. The Box-Behnken model was performed to optimize the extraction condition. The optimal extraction conditions are 5.5 mL of ethyl acetate, 10 min of extraction time and 55 C for extraction temperature. The developed green extraction...
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Thermal Energy Development in Magnetohydrodynamic Flow Utilizing Titanium Dioxide, Copper Oxide and Aluminum Oxide Nanoparticles: Thermal Dispersion and Heat Generating Formularization
PublikacjaThe main aim of this article heat transfer in thermal engineering deals with the production, use, transformation, and transfer of thermal energy. Engineering and industrial fields including food packaging, the production of food additives, electronic cooling, microturbines, etc. heavily rely on heat transmission. Due to its intriguing potential in industries like the production of polymers, paper, crystal glass, etc., scientists...
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Technology-Enhanced Environmental Learning: Co-design of Educational Mobile Application Case
PublikacjaThe process of co-creating an educational mobile application to support environmentally friendly behavior is presented in this paper. The research material consisted of quantitative data collected on the application during the first testing phase by early adopters. The results suggest that the most frequently used features of the app were related to transport and educational activities. While women tended to split their time between...
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URBANIZATION OF METROPOLITAN AREAS – THE IMPORTANCE OF NEW SPATIAL DATA ANALYSIS TOOLS
PublikacjaNowadays, a rapid development of metropolises is connected with the pressure on urbanizing, which leads to a sharp increase in developed areas as well as urbanized areas. As this trend becomes more dynamic, cities sprawl beyond their administrative boundaries, causing spatial disintegration and hindering sustainable development of a given area. Increased dispersion of residential area results in extensive and chaotic spatial development,...
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Landscape as a Potential Key Concept in Urban Environmental Planning: The Case of Poland
PublikacjaRapid urban development increases the consumption of materials, energy, and water, resulting in an overproduction of waste and emissions. These cause many environmental threats, such as ozone layer depletion and rain acidification, leading to climate change. Therefore, the question arises on how to improve the effectiveness of tools that strengthen environmental protection. This discursive article presents an approach stressing...
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SDGs implementation, their synergies, and trade-offs in EU countries – Sensitivity analysis-based approach
PublikacjaSustainable development is one of the most urgent challenges facing humanity. Its basic principle is to improve people’s well-being and maintain it over time. In 2015, the United Nations approved 17 sustainable development goals (SDGs) to ensure a better and sustainable future for all, balancing economic, social and environmental development. SDGs create an ‘indivisible whole’; thus, examining their interactions is crucial. Our...
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Innovation in the strategies of Polish provinces - a comparative study of selected cases
PublikacjaMany strategic management theorists and practitioners believe that the implementation of innovation is one of the key factors determining the company success and show the relationship between long-term innovation strategy and business development strategy. It has also been claimed that similar strategies should be developed for each unit of public administrationMinistry of Economy has set National Development Strategy 2007-2015...
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Fabrication and Characterization of Green Polyurethane Foams with Enhanced Vibration Damping Capability
PublikacjaOver the past decades, there has been an intensive development of the technologies and innovations aimed at increasing the quality of life. This development largely concerns the comfort of use of everyday products that, among others, are products of the automotive, construction, or furniture industries. Considering the increase in the comfort of using products such as cars, houses, and flats, one of the comfort features of their...
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Eicosanoids in Nonalcoholic Fatty Liver Disease (NAFLD) Progression. Do Serum Eicosanoids Profile Correspond with Liver Eicosanoids Content during NAFLD Development and Progression?
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Regionalne obserwatorium kultury w wojewwdztwie podlaskim - uwarunkowania i planowane kierunki rozwoju (Regional Cultural Observatory in the Podlaskie Voivodeship - Conditions and Development Trends)
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Seeking the Factors Predisposing to Local Skin Inflammatory State Development in Children with Type 1 Diabetes (T1DM) Treated with Continuous Subcutaneous Insulin Infusion (CSII)
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S09 Insights into the development of the physical activity environment policy index, a tool for benchmarking implementation of public policies to create healthy physical activity policy environments
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Genes Involved in the Processes of Cell Proliferation, Migration, Adhesion, and Tissue Development as New Potential Markers of Porcine Granulosa Cellular Processes In Vitro: A Microarray Approach
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