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Wyniki wyszukiwania dla: TOXIC
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Application of Fenton oxidation to reduce the toxicity of mixed parabens
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Problems in toxicity analysis - application of fuzzy neural networks
PublikacjaPraca dotyczy zastosowania sztucznych sieci neuronowych do przygotowywania danych do szacowania toksyczności (wody powierzchniowe). Przygotowanie to polega na sztucznym zagęszczaniu zbioru danych, które następnie mogą być wykorzystane do szacowania/modelowania wartości toksyczności na ich podstawie.
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Biosurfactants - Biodegradability, toxicity, efficiency in comparison with synthetic surfactants
PublikacjaBiosurfactants are natural surface active agents produced by variety of bacteria yeast and fungi. A review of their biodegradability, toxicity and efficiency is presented in order to compare their properties with synthetic surfactants. Due to their high efficiency in many applications and environmentally friendly character we tried to apply them in oil refining process. The efficiency of biosurfactants in this application was very...
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Toxicity of the New Psychoactive Substance (NPS) Clephedrone (4-Chloromethcathinone, 4-CMC): Prediction of Toxicity Using In Silico Methods for Clinical and Forensic Purposes
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Sensors for Rapid Detection of Environmental Toxicity in Blood of Poisoned People
PublikacjaRecently, the diagnosis and treatment of poisoned person can be done only in specialized centers. Furthermore, currently used clinical methods of intoxication diagnosis are not sufficient for early detection. Conventional laboratory tests based on urine and blood require professional, high skilled staff, high cost equipment as well as they are arduous and lasting analytical procedures. There is a need to elaborate relatively cheap...
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Preliminary study on toxicity of aquatic ecosystems in Bug river basin
PublikacjaW pracy zaprezentowano badania toksyczności wody, osadów i ścieków wykonane w dorzeczu rzeki Bug w 2001 r. Stosując standardowe mikrobiotesty, określono toksyczność wobec roślin, bakterii i skorupiaków. Wody powierzchniowe w dorzeczu rzeki Bug zakwalifikowano jako nietoksyczne, z wyjątkiem górnego dorzecza i punktu w Terespolu. Większość próbek ścieków wykazywała toksyczność wobec organizmów wskaźnikowych, przy czym różnice w odpowiedzi...
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The effect of processing on the nutritional value and toxicity of foods. Chapter 13
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Analytical and bioanalytical problems associated with the toxicity of elemental sulfur in the environment
PublikacjaWe summarize the state of knowledge on the toxicity and the bioavailability of elemental sulfur. We also present: analytical methods used to determine the elemental sulfur content of samples with complex matrices; and, problems and difficulties encountered while using biotests for samples containing elemental sulfur.
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Mitigating metal-organic framework (MOF) toxicity for biomedical applications
PublikacjaMetal-organic frameworks (MOFs) are a novel class of crystalline porous materials, consisting of metal ions and organic linkers. These hybrid materials are highly porous and have a large specific surface area, making them of great interest for applications in gas separation, energy storage, biomedical imaging, and drug delivery. As MOFs are being explored for biomedical applications, it is essential to comprehensively assess their...
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Molecular Umbrellas Modulate the Selective Toxicity of Polyene Macrolide Antifungals
PublikacjaAntifungal polyene macrolide antibiotics Amphotericin B (AmB) and Nystatin (NYS) were conjugated through the ω-amino acid linkers with diwalled “molecular umbrellas” composed of spermidine-linked deoxycholic or cholic acids. The presence of “umbrella” substituents modulated biological properties of the antibiotics, especially their selective toxicity. Some of the AmB-umbrella conjugates demonstrated antifungal in vitro activity...
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Solar light driven degradation of norfloxacin using as-synthesized Bi 3+ and Fe 2+ co-doped ZnO with the addition of HSO 5 – : Toxicities and degradation pathways investigation
PublikacjaIn this study, solar light responsive Bi3+ and Fe2+ doped ZnO were synthesized and used for photocatalytic degradation of norfloxacin (NOR), an emerging water pollutant. Analysis with Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM), selected area electron...
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Is the presence of Central European strains of Raphidiopsis (Cylindrospermopsis) raciborskii a threat to a freshwater fish? An in vitro toxicological study in common carp cells
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Pre-clinical toxicology and pathology of 9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), a novel anti-cancer agent in male Beagle dogs
PublikacjaPraca zawiera wyniki badań przedklinicznych i morfologicznych pochodnej akrydyny o symbolu C-1748 przeprowadzonych na psach. Wyznaczono maksymalną dawkę tolerowaną oraz przeprowadzono analizy zmiany składu krwi i morfologii jej komórek, pracy aminotransferaz, fosfokinaz, fosfataz i innych enzymów funkcjonalnych. Obserwowano też zachowanie się zwierząt. Stwierdzono, że związek ten wykazuje stosunkowo niską toksyczność, co przy obserwowanej...
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Assessing Acute Toxicity of Selected Packages Internal Layers Extracts using Microtox®
PublikacjaIn the scientific literature related to the widely understood issue of packaging materials designed to have contact with food (food contact materials), there is much information on raw materials used for their production, as well as their physiochemical properties, types and parameters. Unfortunately, not much attention is given to the issues concerning migration of toxic substances from packaging and its actual influence on the...
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Selected issues related to the toxicity of ionic liquids and deep eutectic solvents—a review
PublikacjaGreen Chemistry plays a more and more important role in implementing rules of sustainable development to prevent environmental pollution caused by technological processes, while simultaneously increasing the production yield. Ionic liquids (ILs) and deep eutectic solvents (DESs) constitute a very broad group of substances. Apart from many imperfections, ILs and DESs have been the most promising discoveries in the world of Green...
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Cytotoxicity, acute and subchronic toxicity of ionic liquid, didecyldimethylammonium saccharinate, in rats
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Azo dyes: Sources, occurrence, toxicity, sampling, analysis, and their removal methods
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The role of the enzymatic antioxidant system in cylindrospermopsin-induced toxicity in human lymphocytes
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Toxicity of cylindrospermopsin in human lymphocytes: Proliferation, viability and cell cycle studies
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Impact of Hydrogen Peroxide on the UVC Photolysis of Diclofenac and Toxicity of the Phototransformation Products
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Ozone-Based Technologies for Parabens Removal from Water: Toxicity Assessment
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Are Titania Photocatalysts and Titanium Implants Safe? Review on the Toxicity of Titanium Compounds
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Gold Nanoparticles (AuNPs)—Toxicity, Safety and Green Synthesis: A Critical Review
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Site environment type – The main factor of urban road dust toxicity?
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Binary Mixtures of Selected Bisphenols in the Environment: Their Toxicity in Relationship to Individual Constituents
PublikacjaBisphenol A (BPA) is one of the most popular and commonly used plasticizer in the industry. Over the past decade, new chemicals that belong to the bisphenol group have increasingly been used in industrial applications as alternatives to BPA. Nevertheless, information on the combined effects of bisphenol (BP) analogues is insufficient. Therefore, our current study aimed to find the biological response modulations induced by the...
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Amygdalin: Toxicity, Anticancer Activity and Analytical Procedures for Its Determination in Plant Seeds
PublikacjaAmygdalin (D-Mandelonitrile 6-O--D-glucosido--D-glucoside) is a natural cyanogenic glycoside occurring in the seeds of some edible plants, such as bitter almonds and peaches. It is a medically interesting but controversial compound as it has anticancer activity on one hand and can be toxic via enzymatic degradation and production of hydrogen cyanide on the other hand. Despite numerous contributions on cancer cell lines, the clinical...
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A multi‑criteria approach to investigate spatial distribution,sources, and the potential toxicological effect of polycyclic aromatic hydrocarbons (PAHs) in sediments of urban retention tanks
PublikacjaBottom sediments deposited in retention tanks (RTs) located on two urban streams (Oliwski and Strzyza) in the central part of Gdansk (Poland) were analysed for polycyclic aromatic hydrocarbons’ (PAHs) content. PAHs were extracted from samples with methylene chloride, then the extracts were subjected to clean-up applying the solid phase extraction (SPE) method. Quantitative and qualitative determination of 16 PAHs was performed...
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A link between seasonality and radiation-related toxicity: The big time or time will tell?
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Effect of biochar activation by different methods on toxicity of soil contaminated by industrial activity
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Chemometric estimation of natural water and sediment using toxicity tests and physicochemical parameters
PublikacjaOceny jakości wód dokonano na podstawie analizy chemometrycznej bazy danych monitoringowych, składającej się z wyników testów toksyczności i wyników badań parametrów fizykochemicznych. Badaniom poddano próbki wód powierzchniowych pobrane z Jeziora Turawskiego oraz próbki wód podziemnych pobranych z otworów badawczych wykonanych w jego dnie, jak i wokół niego. Zastosowano następujące metody chemometryczne: analizę wiązkową i analizę...
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Zinc oxide nanoparticles toxicity toDaphnia magna: size-dependent effects and dissolution
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Organomercury Compounds in Environmental Samples: Emission Sources, Toxicity, Environmental Fate, and Determination
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Detrimental effects of chemotherapeutics and other drugs on the endothelium: A call for endothelial toxicity profiling
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Organic micropollutants paracetamol and ibuprofen—toxicity, biodegradation, and genetic background of their utilization by bacteria
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Mitochondria dysfunction is one of the causes of diclofenac toxicity in the green alga Chlamydomonas reinhardtii
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Comparison of the Toxicity of Pristine Graphene and Graphene Oxide, Using Four Biological Models
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<p>Analysis of toxicity and anticancer activity of micelles of sodium alginate-curcumin</p>
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Toxicity of sediments and its relations with the mobility of pollutants on the basis of studies of Lake Turawskie
PublikacjaPraca niniejsza jest raportem z badań nad toksycznością i jej powiązaniem z mobilnością zanieczyszczeń. Moblilność zanieczyszczeń uzależniona jest od pH próbki. Próbki pobierano z Jez. Turawskiego, toksyczność była mierzona przy użyciu testu Microtox (AZUR Environmental, USA).
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Organomercury compounds in environmental samples: emission sources, toxicity, environmental fate and determination.
PublikacjaIn view of the specific properties of mercury and its capability of forming compounds that can be bioaccumulated and biomagnified at successive levels of the trophic pyramid, it has become necessary to gather detailed information on the sources of emission of this element into the environment and its fate there. Moreover, the increasing awareness of the relationship between the toxicity of mercury and its chemical form has sharpened...
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Modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models
PublikacjaThe present study deals with assessment of ecotoxicological parameters of 9 drugs (diclofenac (sodium salt), oxytetracycline hydrochloride, fluoxetine hydrochloride, chloramphenicol, ketoprofen, progesterone, estrone, androstenedione and gemfibrozil), present in the environmental compartments at specific concentration levels, and theirmutual combinations by couples against Microtox® and XenoScreen YES/YAS® bioassays. As the quantitative...
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Assessing Acute Toxicity and Endocrine Disruption Potential of Selected Packages Internal Layers Extracts
PublikacjaThe focus of the present study is migration of toxic substances from food contact materials and its actual influence on the health of the final consumer. Two food packagings (metal cans, TetraPack®) and five simulants medias (water, ethanol, acetic acid, DMSO, artificial saliva) were selected for simulation studies. For assessment of acute toxicity and endocrine disruption potential of extract samples, two biotests (Microtox® and...
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High Signal Resolution Pulse Oximetry as a Prognostic Indicator of Radiotherapy Toxicity: A Pilot Study
PublikacjaIntroduction: Radiotherapy plays a prominent role in the multidisciplinary treatment of cancers. Despite new irradiation techniques, radiation-induced cardiotoxicity remains a leading cause of morbidity and mortality. Therefore, prognostic indicators of radiotherapy toxicity are essential. This study aimed to investigate the influence of applied radiotherapy on the pulse wave recording and thereby on...
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Mathematical Modelling and Effect Size Analysis in Support of Searching for the Proteomic Signature of Radiotherapy Toxicity
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Environmental transformation and nano-toxicity of engineered nano-particles (ENPs) in aquatic and terrestrial organisms
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In Vivo Efficacy, Toxicity Assessment, and Elemental Analysis of Traditionally Used Polyherbal Recipe for Diarrhea
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ALLEVIATING EFFECTS OF ASCORBIC ACID ON LEAD TOXICITY IN GOJI (Lycium barbarum L.) IN VITRO
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Application of chemometric techniques in studies of toxicity of selected commercially available products for infants and children
PublikacjaThe goal of the present study is to assess the impact of the experimental conditions for extraction procedures (time of extraction, thermal treatment and type of extraction media) as applied to several baby and infant products checked for their possible ecotoxicological response when tested by various ecotoxicity tests(Microtox®, Ostracodtoxkit F™and Xenoscreen YES/YAS™). The systems under consideration are multidimensional by...
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Analytical aspects of model compounds toxicity assessment using MTT and Microtox bioanalytica assays
PublikacjaMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds. The effects of the above-mentioned human impact on the environment not only can be noticed in the homeostasis disturbance in ecosystems, but they are also visible with respect to human. The high incidence...
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Toxicity assessment of sediments associated with the wreck of s/s Stuttgart in the Gulf of Gdańsk (Poland)
PublikacjaPrzeprowadzono badania w pobliżu wraku s/s Stuttgart zalegającego przy Polskim wybrzeżu (Zatoka Gdańska) i stanowiącego źródło zanieczyszczenia w formie WWA i PCB. Przeprowadzono oznaczenia śladowych zanieczyszczeń organicznych oraz badania toksykologiczne aby oszacować ryzyko ze strony wraku i jego pozostałości. W wyniku badań można stwierdzić, że tylko siły grawitacyjne i kształt dna morskiego są czynnikami wpływającymi na transport...
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The Substantial Improvement of Amphotericin B Selective Toxicity Upon Modification of Mycosamine with Bulky Substituents
PublikacjaAbstract: Background: It is assumed that the unfavorable selective toxicity of an antifungal drug Amphotericin B (AmB) can be improved upon chemical modification of the antibiotic molecule. Objective: The aim of this study was verification of the hypothesis that introduction of bulky substituents at the amino sugar moiety of the antibiotic may result in diminishment of mammalian vitro toxicity of thus prepared AmB derivatives. Methods:...