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Catalytic Mechanism of Non-Target DNA Cleavage in CRISPR-Cas9 Revealed by Ab Initio Molecular Dynamics
PublikacjaCRISPR-Cas9 is a cutting-edge genome editing technology, which uses the endonuclease Cas9 to introduce mutations at desired sites of the genome. This revolutionary tool is promising to treat a myriad of human genetic diseases. Nevertheless, the molecular basis of DNA cleavage, which is a fundamental step for genome editing, has not been established. Here, quantum–classical molecular dynamics (MD) and free energy methods are used...
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Temperature Evolution, Material Flow, and Resulting Mechanical Properties as a Function of Tool Geometry during Friction Stir Welding of AA6082
PublikacjaThe friction stir welding process was simulated for joining AA6082 aluminum alloy with the use of the computational fluid dynamics method. Two different tool geometries were used—a tapered cylindrical pin (simple pin) and a hexagonal pin with grooves (complex pin). The analysis of the simulations performed was discussed in terms of temperature evolution during the process, total heat input, residual stresses and material flow....
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The Comparison of the Web GIS Applications Relevant for 4D Models Sharing
PublikacjaThe paper presents results of the project: Cultural Heritage Through Time (CHT 2, http://cht2-project.eu) realized accomplished within the framework of the “Joint Programming Initiative in Cultural Heritage” JPI-CH (http://www.jpi-culturalheritage.eu) by an international consortium: Politecnico di Milano (IT), Newcastle University (UK), Salamanca University (ES), and Stanislaw Staszic Scientific Association SSSA (a non-profit...
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An Estimation of the Efficiency of Public Research Institutes in Poland – DEA Approach
PublikacjaObjective: The purpose of this paper is to measure and assess the efficiency of research institutes in Poland. The institutes operate on the basis of various legal frameworks, but they serve a common purpose and have a joint area of activity, research and development.Research Design & Methods: We used the SBM model, a component of the non-parametric Data Envelopment Analysis (DEA) methodology, to analyse the efficiency...
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Socioemotional Wealth (SEW) of Family Firms and CEO Behavioral Biases in the Implementation of Sustainable Development Goals (SDGs)
PublikacjaAgreed upon by the UN member states, Agenda 2030 assumes joint action for long- term sustainable development. These actions are focused on the implementation of 17 Sustainable Development Goals (SDGs), where actions are assumed to lead to the suppression of negative externalities of human activity. It is stressed that the objectives of sustainable development can only be achieved through deep institutional changes in most dimensions...
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Anionic states of C6Cl6 probed in electron transfer experiments
PublikacjaThis is the first comprehensive investigation on the anionic species formed in collisions of fast neutral potassium (K) atoms with neutral hexachlorobenzene (C6Cl6) molecules in the laboratory frame range from 10 up to 100 eV. In such ion-pair formation experiments, we also report a novel K+ energy loss spectrum obtained in the forward scattering giving evidence of the most accessible electronic states. The vertical electron affinity...
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Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 50, the 4th joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of 12 targets, including 6 dimers, 3 trimers, and 3 higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly...
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Can architecture be 11-dimensional? The nature of space in the architecture of the digital world era
PublikacjaThis research aims to explore the development of architectural theories about ‘architectural dimensions’ and look at architecture as a multidimensional space. It is important to understand that with today's development of virtual reality technology and through the combination of theories of physics and architecture, a new possibility of creating space has emerged. The arguments are made through inductive reasoning and grounded...
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Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 54, the 5th joint CASP-CAPRI protein assembly prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo-trimers, 13 heterodimers including 3 antibody–antigen complexes, and 7 large assemblies. On average 70 CASP and CAPRI predictor groups, including more than 20 automatics servers, submitted models for each target. A total of 21 941 models submitted by these groups...
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Fast Re-Design of Multi-Band Antennas by Means of Orthogonal-Direction Geometry Scaling and Local Parameter Tuning
PublikacjaApplication-driven design of antenna systems fosters a reuse of structures that have proven competitive in terms of their electrical and field performance, yet have to be re-designed for a new application area. In practice, it most often entails relocation of the operating frequencies or bandwidths, which is an intricate endeavor, normally requiring utilization of numerical optimization techniques. If the center frequencies of...
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The effect of Ag, Au, Pt, and Pd on the surface properties, photocatalytic activity and toxicity of multicomponent TiO2-based nanomaterials
PublikacjaMulticomponent TiO2-based nanomaterials (MC-NMs) show better physicochemical properties than their individual components or bulk materials. However, the same unique properties that offer innovative applications might also pose unknown risks to human health and the environment. In this context, TiO2- based nanomaterials with a mixture of noble metal precursors (Ag, Au, Pt, and Pd) for large-scale technological applications in air...
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Impact of digital signal processing on FOC current feedback in high-speed PMSM drive
PublikacjaIn applications where size and weight of the electric motor are among major design concerns, Permanent Magnet Synchronous Motors (PMSMs) with wide operational speed-range are commonly preferred. Due to limited inverter switching frequency, high-speed operation of a drive results in a low ratio between the switching frequency and the fundamental frequency of motor voltage. Such operating conditions have been recently identified...
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Creep rupture study of dissimilar welded joints of P92 and 304L steels
PublikacjaThe present work investigates the high-temperature tensile and creep properties of the dissimilar metal weld joints of 304L austenitic stainless steel (SS) and P92 creep strength-enhanced ferritic-martensitic (CSEF/M) steel under diferent testing condition. Thermanit MTS 616 fller rod (P92 fller) and the multi-pass tungsten inert gas (TIG) welding process were used to create the dissimilar weld connection. The ultimate tensile...
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Engineering and Management of Space Systems
PublikacjaDynamic development of the European space sector results in a necessity for suitable Higher Education Institution graduates. Current study programs of Aerospace Technology are focused on the field of mechanical engineering. Although engineering methods for design, construction and assembly of mechanical systems are covered, interdisciplinarity and life cycle aspects are not considered in a sufficient degree. Due to the increasing...
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Tadeusz Borzęcki dr inż.
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Aleksandra Parteka dr hab. inż.
OsobyAbout me: I am an associate professor and head of doctoral studies at the Faculty of Management and Economics, Gdansk University of Technology (GdanskTech, Poland). I got my MSc degree in Economics from Gdansk University of Technology (2003) and Universita’ Politecnica delle Marche (2005), as well as MA degree in Contemporary European Studies from Sussex University (2006, with distinction). I received my PhD in Economics...
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Malaysia International Conference on Communications (Joint IEEE Malaysia International Conference on Communications and IEEE International Workshop on Intelligent Signal Processing and Communication Systems [MICC/ISPACS])
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Recent developments in biological sample testing methods for the confirmation of gestational exposure to tobacco smoke anddrugs of abused
PublikacjaSubstance use is most prevalent in reproductive-aged people also by women during pregnancy. In national prevalence surveys among women aged 15 to 44 years, 10.8 % of women reported using alcohol during pregnancy, 17 % reported smoking during pregnancy, and 4.4 % reported abusing any illicit substances during pregnancy. Virtually all illegal drugs, such as heroin and cocaine, pose dangers to a pregnant woman. Legal substances, such...
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Investigation of Mechanical and Microstructural Properties of Welded Specimens of AA6061-T6 Alloy with Friction Stir Welding and Parallel Friction Stir Welding Methods
PublikacjaThe present study investigates the effect of two parameters of process type and tool offset on tensile, microhardness, and microstructure properties of AA6061-T6 aluminum alloy joints. Three methods of Friction Stir Welding (FSW), Advancing Parallel-Friction Stir Welding (AP-FSW), and Retreating Parallel-Friction Stir Welding (RP-FSW) were used. In addition, four modes of 0.5, 1, 1.5, and 2 mm of tool offset were used in two welding...
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Proportional-Derivative and Model-based Controllers used for a Serial Type Manipulator in case of a Variable Mass Payload
PublikacjaIn the paper, numerical analysis of dynamics of a variable mass system is considered. Its reference example is a serial-like manipulator composed of revolute joints and rigid bodies. Payload of its gripper is considered as its variable mass element (mass and inertia irregularly between subsequent payloads). For the rest of the system, inertia parameters are considered as known (precisely identified during the assembling process)....
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Investigation of low-temperature cracking in newly constructed high-modulus asphalt concrete base course of a motorway pavement
PublikacjaThe paper presents the issue of low-temperature transverse cracks which have developed in newly constructed base courses made of high-modulus asphalt concrete mix (HMAC). Numerous transverse cracks developed in the analysed HMAC base during the winter season before the pavement was actually completed, both at the transverse joint locations and in the areas between them. This had not happened so far on such a scale during road construction...
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Underwater wet welding of S1300 ultra-high strength steel
PublikacjaMarine Structures Volume 81, January 2022, 103120 Underwater wet welding of S1300 ultra-high strength steel Author links open overlay panelJacekTomkówGrzegorzRogalski https://doi.org/10.1016/j.marstruc.2021.103120 Get rights and content Under a Creative Commons licenseopen access Highlights • Technological method of S1300 steel underwater weldability improving was proposed. • Number of cracks and hardness of welded joints was...
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Tackling microplastics pollution in global environment through integration of applied technology, policy instruments, and legislation
PublikacjaMicroplastic pollution is a serious environmental problem that affects both aquatic and terrestrial ecosystems. Small particles with size of less than 5 mm, known as microplastics (MPs), persist in the environment and pose serious threats to various species from micro-organisms to humans. However, terrestrial environment has received less attention than the aquatic environment, despite being a major source of MPs that eventually...
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Underwater in situ local heat treatment by additional stitches for improving the weldability of steel
PublikacjaIn this paper the influence of in situ local heat treatment performed by additional stitches on the weldability of high-strength low-alloy (HSLA) S355J2C+N steel was tested. The investigated steel is characterized by high susceptibility to cold cracking. It is necessary to find a method to improve the quality of welded joints. The local heat treatment was applied as an eect of bead-on plate welding made on the face of a Tekken...
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Analiza porównawcza metod zwiększania nośności i sztywności stalowych, doczołowych węzłów śrubowych.
PublikacjaInnowacyjna, w porównaniu z dotychczas stosowanym sposobem, metoda obliczania nośności stalowych węzłów została wdrożona wraz z normami europejskimi. Pozwala ona dokładniej odwzo-rować rzeczywistą pracę poszczególnych części węzła, gdyż wynik obliczeń uzależniony jest od znacznie większej liczby zmiennych. Dzięki postępowi technologicznemu w zakresie metalurgii oraz badaniom naukowym obecnie możliwe jest wzmacnianie połączeń...
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Model-Based Adaptive Machine Learning Approach in Concrete Mix Design
PublikacjaConcrete mix design is one of the most critical issues in concrete technology. This process aims to create a concrete mix which helps deliver concrete with desired features and quality. Contemporary requirements for concrete concern not only its structural properties, but also increasingly its production process and environmental friendliness, forcing concrete producers to use both chemically and technologically complex concrete...
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Uncertainty Quantification of Additive Manufacturing Post-Fabrication Tuning of Resonator-Based Microwave Sensors
PublikacjaReconfigurability, especially in terms of the ability of adjusting the operating frequency, has become an important prerequisite in the design of modern microwave components and systems. It is also pertinent to microwave sensors developed for a variety of applications such as characterization of material properties of solids or liquids. This paper discusses uncertainty quantification of additive-manufacturing-based post-fabrication...
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Impacts in case of triple unilaterally constrained system
PublikacjaThe this paper focus on the behaviour of a “rigid” body biting into another “rigid” body, with some nonzero relative velocity. In the presently considered case, the introduced collision appears between a selected element of a multibody structure and its reference body being interpreted as the motionless ground. Instead of the classic case, described in a number of dissertations, where a single impacting contact is considered, three...
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Ryszard Staniszewski PhD, DSc
OsobyAbsolwent Technikum Energetycznego w Poznaniu (1988 r.) oraz Wydziału Melioracji i Inżynierii Środowiska AR Poznań (1994 r.). Przebieg pracy zawodowej: 2019; Katedra Ekologii i Ochrony Środowiska, UP w Poznaniu; profesor UPP 2015; Katedra Ekologii i Ochrony Środowiska, UP w Poznaniu; adiunkt z habilitacją 2002; Katedra Ekologii i Ochrony Środowiska, UP w Poznaniu; adiunkt 1996; Katedra Ekologii i Ochrony Środowiska Rolniczego,...
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Mirosław Kazimierz Gerigk dr hab. inż.
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Kazimierz Darowicki prof. dr hab. inż.
OsobyStudia wyższe ukończyłem w czerwcu 1981 roku po zdaniu egzaminu dyplomowego i obronie pracy magisterskiej. Opiekunem pracy magisterskiej był dr hab. inż. Tadeusz Szauer. W roku 1991, 27 listopada uzyskałem stopień naukowy broniąc pracę doktorską zatytułowaną „Symulacyjna i korelacyjna analiza widm immitancyjnych inhibitowanej reakcji elektrodowej”. Promotorem pracy był prof. dr hab. inż. Józef Kubicki (Wydział Chemiczny...
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Ochrona usług masowej dystrybucji multimediów z wykorzystaniem metod fingercastingu
PublikacjaW rozdziale przedstawione zostały problemy ochrony usług masowej dystrybucji treści multimedialnych w sieciach komputerowych przed kopiowaniem i nielegalnym rozpowszechnianiem multimediów, z wykorzystaniem metod fingerprintingu, a w szczególności podgrupy tych metod - metod fingercastingu. W odróżnieniu od innych metod fingerprintingu, metody fingercastingu wykorzystują połączenia grupowe (ang. multicast), co prowadzi do znacznego...
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Advancing the evidence base for public policies impacting on dietary behaviour, physical activity and sedentary behaviour in Europe: The Policy Evaluation Network promoting a multidisciplinary approach
PublikacjaNon-communicable diseases (NCDs) are the leading cause of global mortality. As the social and economic costs of NCDs have escalated, action is needed to tackle important causes of many NCD’s: low physical activity levels and unhealthy dietary behaviours. As these behaviours are driven by upstream factors, successful policy interventions are required that encourage healthy dietary behaviours, improve physical activity levels and...
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"Shaping space" programme as a tool for educating youth about architecture
PublikacjaThe Polish Architectural Policy’s vision of a systematic promotion of spatial culture has made its way into the national curriculum for 2009 – 2016 designed for various stages of child and teenager education. The objective of this effort was to furnish a basis for a system of architectural education which allows teaching society to be more conscious in their decisions as to spatial order with the effect of improving the quality...
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Ocena odporności na zużycie ścierne stopów Ti na elementy pary trącej endoprotez stawu kolanowego
PublikacjaNajczęściej stosowanym biomateriałem tytanowym na elementy endoprotez stawu kolanowego jest stop Ti6Al4V. Z uwagi na zawartość wanadu, zaliczanego do pierwiastków o dużej toksyczności podejmowane są działania w kierunku zastąpienia wskazanego stopu - stopami bezwanadowymi. Jednym z najbardziej obiecujących jest stop Ti13Nb13Zr zawierający w swoim składzie jedynie pierwiastki witalne, niewywołujące stanów zapalnych i odczynów...
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Literature review of user needs, toward user requirements
PublikacjaThis report has been developed in the frame of the IEA SHC Task 61 Subtask A “User requirements”. The main objective was to rethink and reformulate user requirements to lighting (daylighting and electric lighting) in public buildings on the basis of a thorough literature study. The work is a joint effort of a number of scientists and represents collective knowledge in this topic. The concept of Lighting quality is the one, among...
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Mohsan Ali Master of Science in Computer Science
OsobyMohsan Ali is a researcher at the University of the Aegean. He won the Marie-Curie Scholarship in 2021 in the field of open data ecosystem (ODECO) to pursue his PhD degree at the University of the Aegean. Currently, he is working on the technical interoperability of open data in the information systems laboratory; this position is funded by ODECO. His areas of expertise are open data, open data interoperability, data science, natural...
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Embedded system using Bluetooth Low Energy sensors for smart farming applications
PublikacjaThe main goal of this Bachelor of Engineering project titled Embedded system using Bluetooth Low Energy sensors for smart farming applications is to create a prototype of a system consistent with Agriculture 4.0 concept using Bluetooth Low Energy (BLE) technology. Developed solution shall be easy in implementation and its main functionality shall be periodic gathering of data from environmental sensors...
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Orken Mamyrbayev Professor
Osoby1. Education: Higher. In 2001, graduated from the Abay Almaty State University (now Abay Kazakh National Pedagogical University), in the specialty: Computer science and computerization manager. 2. Academic degree: Ph.D. in the specialty "6D070300-Information systems". The dissertation was defended in 2014 on the topic: "Kazakh soileulerin tanudyn kupmodaldy zhuyesin kuru". Under my supervision, 16 masters, 1 dissertation...
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Mariusz Figurski prof. dr hab. inż.
OsobyDyrektor Centrum Modelowania Meteorologicznego Instytut Meteorologii i Gospodarki Wodnej - Państwowy Instytut Badawczy. Urodził się 27 kwietnia 1964 roku w Łasinie. Egzamin maturalny złożył w 1983 roku po ukończeniu II Liceum Ogólnokształcącego im. Jana III Sobieskiego w Grudziądzu, Studia wyższe w trybie indywidualnym ukończył w 1989 (10.07.1989) na Wydziałach Elektromechanicznym i Inżynierii Lądowej i Geodezji Wojskowej Akademii...
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FOODINTEGRITY Zapewnienie integralności sektora spożywczego w Europie
ProjektyProjekt realizowany w Katedra Technologii Koloidów i Lipidów zgodnie z porozumieniem 613688 z dnia 2016-03-27