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Wyniki wyszukiwania dla: UGT METABOLIC TRANSFORMATIONS
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Anaplastic large cell lymphoma, ALK negative - Female, 61 - Tissue image [9230729557257491]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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FURTHER REMARKS ON THE NEO-CLASSICAL NAVIER-STOKES EQUATIONS
PublikacjaThe seminal Navier-Stokes equations have been stated yet before creation of principles of thermodynamics and the first and second laws. In the literature there is the common opinion that the Navier-Stokes equations cannot be taken as a thermodynamically correct model of “working fluid” which is able to describe transformation of “ heat” into “work” and vice versa. Therefore, in the paper, a new exposition of thermodynamically...
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Modeling and simulation of blood flow under the influence of radioactive materials having slip with MHD and nonlinear mixed convection
PublikacjaRadioactive materials are widely in industry, nuclear plants and medical treatments. Scientists and workers in these fields are mostly exposed to such materials, and adverse effects on blood and temperature profiles are observed. In this regard, objective of the current study is to model and simulate blood based nanofluid with three very important radioactive materials, named as Uranium dioxide (UO2), Thorium dioxide (ThO2) and...
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Scaling scrum with a customized nexus framework: A report from a joint industry‐academia research project
Publikacjaespite a wide range of scaling frameworks available, large-scale agile transformations are not straightforward undertakings. Few organizations have structures in place that fit the predefined workflows – while once one applies an off-the-shelf framework outside of its prescribed process, guidance quickly runs out. In this paper, we demonstrate how to instantiate a method configuration process using a lightweight experimental approach...
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Kinetics of Intermetallic Phase Precipitation in Manual Metal Arc Welded Duplex Stainless Steels
PublikacjaThe article presents the influence of heat treatment on the kinetics of transformations in lean duplex LDX2101 steel and a weld made of standard duplex 2209 material, which was welded by manual metal arc welding. Changes in the microstructure, hardness, and magnetic phase content were analyzed after heat treatment was conducted at a temperature of 800 °C for a period ranging from 15 to 1440 min. Light and scanning microscopy, Vickers...
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A Series of Novel 3D Coordination Polymers Based on the Quinoline-2,4-dicarboxylate Building Block and Lanthanide(III) Ions—Temperature Dependence Investigations
PublikacjaA series of novel 3D coordination polymers [Ln2(Qdca)3(H2O)x]yH2O (x = 3 or 4, y = 0–4) assembled from selected lanthanide ions (Ln(III) = Nd, Eu, Tb, and Er) and a non-explored quinoline- 2,4-dicarboxylate building block (Qdca2 = C11H5NO4 2) were prepared under hydrothermal conditions at temperatures of 100, 120, and 150 C. Generally, an increase in synthesis temperature resulted in structural transformations and the formation...
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Antioxidant and antimicrobial activity of fermented beverages obtained from fruit pomace
PublikacjaFruit pomace should not be considered as a waste product but as a by-product as it contains a lot of valuable components such as dietary fiber, bioactive compounds and a source of nutrients. The reasonable way to utilize these by-products, both fresh or dried, could be the fermentation of its extracts, leading to beverages with functional properties. In our research, we checked the possibility of using chokeberry, apple and...
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Selected adipocytokines in patients with an incidentally discovered pheochromocytoma
PublikacjaBACKGROUND: Adipose tissue secretes many adipokines and cytokines, which may be an additional risk factor of cardiovascular and metabolic diseases in patients with an incidentally discovered pheochromocytoma (PHEO). The aim of the study was to investigate levels of selected adipocytokines in these patients. METHODS: This prospective study included 12 patients with an incidentally discovered PHEO and 18 healthy participants. In...
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Determination of bromhexine and its metabolites in equine serum samples by liquid chromatography – Tandem mass spectrometry: Applicability to the elimination study after single oral dose
PublikacjaBromhexine (BH), expectorant used in the treatment of respiratory disorders associated with viscid or excessive mucus, is not permitted for use in the competing horse by many authorities in horseracing and Olympic disciplines. Metabolic studies are of the great importance in anti-doping field because they allow for updating the selection of the most appropriate markers for prohibited substances, such as metabolites present at higher...
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Honey antibacterial activity: A neglected aspect of honey quality assurance as functional food
PublikacjaBackground Honey is considered as a functional food with health-promoting properties. Its potent antibacterial and antibiofilm effects are the major attributes of so called ‘medical-grade honey’ which is topically used for the treatment of burns, wounds and skin disorders. Nevertheless, the current set of honey quality parameters adopted in the European Union do not include its biological properties. Furthermore, in light of the...
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A mechanistically approached review upon assorted cell lines stimulated by athermal electromagnetic irradiation
PublikacjaThe probable influence of electromagnetic irradiation on cancer treatment has been deduced from the interaction of artificial electromagnetic emissions with biological organisms. Nonetheless, the suspected health effects induced by electromagnetic-based technology imply that such a treatment may contaminate the adjacent healthy cells. Thus, gaining mechanistic insights into the problem is required to avoid athermal health hazards....
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From the pills to environment – Prediction and tracking of non-steroidal anti-inflammatory drug concentrations in wastewater
PublikacjaThe extend of environment pollution by pharmaceuticals is in a stage that required more automatic and integrated solutions. The non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most popular pharmaceutical in the world and emerging pollutants of natural waters. The aim of the paper was to check the correlation of the sales data of selected NSAIDs (ibuprofen, naproxen, diclofenac) and their concentration in the WWTP...
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Trace metals in skeletal calcite of echinoderms from the Barents Sea
PublikacjaThis study investigates the skeletal accumulation of selected elements (Al, Ag, As, Ca, Co, Cr, Cu, Fe, Hg, K, Mg, Mn, Na, Pb, Sr, Zn) in echinoderms inhabiting Barents Sea, an area impacted by human activities from northern Norway and Kola Peninsula, known sources of metal pollution. The primary aim was to have insight whether metals incorporation in the skeleton of Arctic echinoderms is regulated physiologically by the organism...
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Wpływ nadekspresji izoenzymów P450 oraz UGT na odpowiedź komórkową indukowaną przez przeciwnowotworowe pochodne akrydonu. Rola podwyższonego stężenia metabolitów w komórce czy udział receptorów jądrowych PXR i CAR w tych procesach?
ProjektyProjekt realizowany w Wydział Chemiczny zgodnie z porozumieniem UMO-2013/09/B/NZ3/00003 z dnia 2014-03-11
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2022_Elective Design II_S_Hudnik_K_Zyczkowska_There is no Planet B
Kursy OnlineThere is no Planet B The studio will use practical interventions to explore how climate change is affecting transformations in urban / non-urban space in Gdansk. Through the identification of problems and the importance of reading the consequences in space and architecture, students will learn about the method of opening a critical public debate. Through a variety of topics and actions – micro interventions, they will record their...
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Nontoxic multinodular goitre - Female, 66 - Tissue image [7110729594544291]
Dane BadawczeThis is the histopathological image of THYROID GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Nontoxic multinodular goitre - Female, 66 - Tissue image [7110729594543271]
Dane BadawczeThis is the histopathological image of THYROID GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Nontoxic multinodular goitre - Female, 66 - Tissue image [7110729594547851]
Dane BadawczeThis is the histopathological image of THYROID GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Nontoxic multinodular goitre - Female, 66 - Tissue image [7110729594544111]
Dane BadawczeThis is the histopathological image of THYROID GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Nontoxic multinodular goitre - Female, 66 - Tissue image [7110729594543641]
Dane BadawczeThis is the histopathological image of THYROID GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Emulsification alters simulated gastrointestinal proteolysis of β-casein and β-lactoglobulin
PublikacjaWe have studied the effect of the adsorption of milk proteins at the oil-water interface on their digestibility in simulated gastrointestinal environment. The investigations aimed to characterize how both the breakdown of the adsorbed proteins and the interactions with physiological surfactants, phosphatidylcholine (PC) and bile salts (BS), influence structural transformations of model, protein-stabilized food emulsions in the...
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Data augmentation for improving deep learning in image classification problem
PublikacjaThese days deep learning is the fastest-growing field in the field of Machine Learning (ML) and Deep Neural Networks (DNN). Among many of DNN structures, the Convolutional Neural Networks (CNN) are currently the main tool used for the image analysis and classification purposes. Although great achievements and perspectives, deep neural networks and accompanying learning algorithms have some relevant challenges to tackle. In this...
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Pealizacija inicjatiw wostocznogo partnerstwa w Azerbajdżane
PublikacjaAzerbaijan established political relations with the EU during the implementation of TACIS Programme projects and signed the Partnership and Cooperation Agreement with the EU in 1996. It joined the European Neighbourhood Policy in 2004 and the Eastern Partnership programme in 2009. Despite the sceptical attitude taken by Azerbaijan's government towards the Eastern Partnership initiative, the EU earmarked further funds for Azerbaijan for 2011 – 2014 as part of the European Neighbourhood and Partnership Instrument. During the third Eastern Partnership summit in Vilnius in November 2013, Azerbaijan signed only an agreement concerning visa facilitations and readmission. However, it also undertook certain measures as part of the five Eastern Partnership initiatives. In the framework of the Integrated Border Management Programme, Azerbaijan implemented projects connected with improving the access of resettled people to the judicial system, creation of electronic border control systems, social protection, increasing public awareness to eliminate domestic violence, improving assimilation of asylum - seekers and immigrants, and supporting occupational health organisations. Activities aimed at supporting SMEs included training for entrepreneurs, promotional conferences and loans to the SME sector. Recommendations of the initiative promoting the creation of regional electrical and renewable energy markets were implemented by Azerbaijan in the form of 33 projects as part of the INOGATE Programme. With respect to environmental management, Azerbaijan developed a digital regional atlas of natural disasters, and with respect to natural disaster mitigation it planned population protection measures. Azerbaijan was ranked last but one in the evaluation presented in the annual report prepared by the EU. The transformation process in this country has been slow and illusory in certain aspects. Nevertheless, the EU has continued its Eastern Partnership initiative activities, allocating between EUR 252,000 and 308,000 for transformations in Azerbaijan
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The Employment of Ukrainians as an Opportunity to Fill the Labour Market in Poland – Selected Issues
PublikacjaThe labour market in Poland has undergone signifi cant transformations over the past two decades. The observed changes have been infl uenced by various factors related to, among other things, the possibility of free movement of the population resulting from membership of EU structures, demographic changes, technological changes, and the automation and robotisation of production processes. Demographic change is becoming a signifi...
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INVESTIGATIONS OF THE EMISSION CHARACTERISTICS OF A DUAL-FUEL GAS TURBINE COMBUSTION CHAMBER OPERATING SIMULTANEOUSLY ON LIQUID AND GASEOUS FUELS
PublikacjaT his study is dedicated to investigations of the working process in a dual-fuel low-emission combustion chamber for a floating vessel’s gas turbine. As the object of the research, a low-emission gas turbine combustion chamber with partial premixing of fuel and air inside the outer and inner radial-axial swirls was chosen. The method of the research is based on the numerical solution of the system of differential...
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Tetracycline degradation for wastewater treatment based on ozone nanobubbles advanced oxidation processes (AOPs) – Focus on nanobubbles formation, degradation kinetics, mechanism and effects of water composition
PublikacjaPresence of pharmaceuticals, especially antibiotics, in industrial and domestic effluents causes serious damage to the environment. Classic wastewater treatment processes, in particular conventional biological treatment methods, are not sufficient to rapidly eliminate antibiotics. Typically, Advanced Oxidation Processes (AOPs) based on activation of hydrogen peroxide, ozone or persulfate for formation of particular type of radical...
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Kształtowanie nowej tożsamości regionalnej w przestrzeniach dominacji wody na Żuławach Delty Wisły
PublikacjaCelem naukowym rozprawy jest sformułowanie kierunku zagospodarowania przestrzennego regionu Żuław Delty Wisły. To unikatowy w skali europejskiej region, który jest fenomenem cywilizacji hydraulicznej i dominacji wody. Proces polderyzacji, który rozpoczął się już w XIII wieku doprowadził do utworzenia historycznych układów urbanistycznych. W roku 1945 nastąpiło przerwanie ciągłości kulturowej. Współcześnie na obszarze Żuław istnieją...
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Removal of VOCs from air and assessment of dominant species in a peat-perlite biotrickling filter
PublikacjaAir pollution has become a major concern because it is inevitably connected with the rapid development of both industrial and residential areas. Volatile organic compounds (VOCs) are emitted from various anthropogenic sources e.g. transportation, factories or landfills as well as recycling factories. It is problematic not only because of the direct impact on humans and environment but also from economy viewpoint as it increases...
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Comparison of nitrogen and VFA removal pathways in autotrophic and organotrophic anammox reactors
PublikacjaOrganotrophic anammox is a promising process for treating both nitrogen and organic containing wastewater than that of the traditional autotrophic anammox for sole nitrogen removal. However pathways of nitrogen removal particularly at metagenomic level in both processes are still unknown. Here we report, metabolic pathways of nitrogen removal in two lab-scale sequencing batch reactors (SBR), one autotrophic and another organotrophic...
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Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis
PublikacjaCancer continues to be a leading cause of death worldwide, making the development of new treatment methods crucial in the fight against it. With cancer incidence rates increasing worldwide, ongoing research must focus on identifying new and effective ways to prevent and treat the disease. The combination of herbal extracts with chemotherapeutic agents has gained much interest as a novel strategy to combat cancer. Rumex obtusifolius...
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Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
PublikacjaPeople are constantly exposed to phthalates, due to their common use in the production of plastics, pharmaceuticals, cosmetics and skin care products. The ability of phthalates to disrupt endocrine signaling, leading to developmental, reproductive and metabolic defects, has been studied, yet how phthalates interfere with these biological functions is still unclear. To uncover DBP interacting molecular pathways, we raised Drosophila...
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Bioactivation of Konjac Glucomannan Films by Tannic Acid and Gluconolactone Addition
PublikacjaWound healing is a dynamic process that requires an optimal extracellular environment, as well as an accurate synchronization between various cell types. Over the past few years, great efforts have been devoted to developing novel approaches for treating and managing burn injuries, sepsis, and chronic or accidental skin injuries. Multifunctional smart-polymer-based dressings represent a promising approach to support natural healing...
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Fluoride-induced stress shapes partial denitrification granules to sustain microbial metabolism
PublikacjaThe presence of fluoride ions (F-) in nitrogen-rich wastewater from photovoltaic and semiconductor industries introduces a significant challenge to biological treatment processes, particularly for the innovative partial denitrification (PD) process, which supplies nitrite for anaerobic ammonium oxidation (Anammox). This study provides the first comprehensive and systematic investigation of the effects of F- stress on the granule-based...
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External electron donor and transporter of iron triggers the paths to enhancing collaboration of anammox and denitrification in granular sludge: Bacterial resilience and synergetic promotion mechanism
PublikacjaAutotrophic nitrogen removal via anaerobic ammonium oxidation (anammox) technology currently faces sig nificant challenges in treating low-strength wastewater due to inefficient retention of bacteria and unstable activity under fluctuating conditions. This study demonstrates enhanced resilience and stability of anammox coupled with partial denitrification (PD) in granular sludge, assisted by ferric iron (Fe(III)) and nano zero-valent iron...
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SZTUKA WIZUALNA W OBIEKTACH MEDYCZNYCH = VISUAL ARTS IN MEDICAL FACILITIES
PublikacjaWspółczesna architektura obiektów służby zdrowia podlega dynamicznym przeobrażeniom formalnym wynikającym zarówno z rozwoju technologii medycznych, zmian zachodzących w podejściu wobec pacjenta. Narastający w naukach medycznych kierunek holistyczny ustawia pacjenta jako użytkownika w trzech wymiarach: biologicznym, społecznym i psychologicznym. Stąd pojawiające się w procesie projektowym dotyczącym szpitali czy przychodni nowe...
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Poprawa jakości klasyfikacji głębokich sieci neuronowych poprzez optymalizację ich struktury i dwuetapowy proces uczenia
PublikacjaW pracy doktorskiej podjęto problem realizacji algorytmów głębokiego uczenia w warunkach deficytu danych uczących. Głównym celem było opracowanie podejścia optymalizującego strukturę sieci neuronowej oraz zastosowanie uczeniu dwuetapowym, w celu uzyskania mniejszych struktur, zachowując przy tym dokładności. Proponowane rozwiązania poddano testom na zadaniu klasyfikacji znamion skórnych na znamiona złośliwe i łagodne. W pierwszym...
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Cloning and characterization of a novel cold-active glycoside hydrolase family 1 enzyme with beta-glucosidase, beta-fucosidase and beta-galactosidase activities.
PublikacjaBackground: Cold-active enzymes, sourced from cold-adapted organisms, are characterized by high catalytic efficiencies at low temperatures compared with their mesophilic counterparts, which have poor activity. This property makes them advantageous for biotechnology applications as it: (i) saves energy costs, (ii) shortens the times for processes operated at low temperatures, (iii) protects thermosensitive substrates or products...
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Economic vitality of Polish suburbs
PublikacjaSince 1989, Poland has been undergoing major political, social and economic transformations. The effects of these changes are visible on several levels, including the field of urban planning, where they manifested themselves as the birth of the suburbanization process. In the field of economics, it could be noticed that since 1989, the SME sector has been awakening very dynamically. Correlation of the parallel development of these...
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Street Art and Urban Regeneration. Case Study Gdansk and Rome.
PublikacjaStreet art plays an important role in urban planning as a transforming engine to regenerate the public spaces and in the processes of participation. The article analyzes two main topics. The first one focuses on the urban serving as a support for spatial and cultural strategies in urban redevelopment projects. The second one is related to the potential of micro urban interventions as a strategy for a wider involvement of inhabitants...
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Marta Rusnak, Marta Szmigiel, Malwina Geniusz, Zofia Koszewicz, Monika Magdziak-Tokłowicz, Exploring the impact of cultural context on eye-tracking studies of architectural monuments in selected European cities: Sustainable heritage management.
PublikacjaSustainable management of architectural heritage requires conducting an inclusive diagnosis of users' opinions, considering both residents and tourists as the recipients of urban space. Given the cultural diversity within these groups, proposing the use of eye-trackers (ET) as an alternative to traditional public consultation prompts the need to assess the method's advantages and disadvantages. It remains uncertain whether individuals...
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Exploring the impact of cultural context on eye-tracking studies of architectural monuments in selected European cities: Sustainable heritage management.
PublikacjaSustainable management of architectural heritage requires conducting an inclusive diagnosis of users’ opinions, considering both residents and tourists as the recipients of urban space. Given the cultural diversity within these groups, proposing the use of eye-trackers (ET) as an alternative to traditional public consultation prompts the need to assess the method’s advantages and disadvantages. It remains uncertain whether individuals...
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Applications of Tensor Analysis in Continuum Mechanics
PublikacjaA tensor field is a tensor-valued function of position in space. The use of tensor fields allows us to present physical laws in a clear, compact form. A byproduct is a set of simple and clear rules for the representation of vector differential operators such as gradient, divergence, and Laplacian in curvilinear coordinate systems. The tensorial nature of a quantity permits us to formulate transformation rules for its components...
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‘The Urban Walk Architecture Talk’— Bridging Socially Engaged Art, Urban Processes and Cultural Development
Publikacja“Urban Walk—Architecture Talk” is a project based on an elective seminar under the same title organized at the Faculty of Architecture of Gdańsk University of Technology. It aims at getting familiar with the topic of multi-layer and multi-sensory reception of public space, mainly by recognizing the needs of its users. Additionally, it deals with the consequences of such perception and the use of space in order to build more complete...
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Art and Healthcare - Healing Potential of Artistic Interventions in Medical Settings
PublikacjaThe stereotype of a machine for healing seems to be well rooted in common thinking and social perception of hospital buildings. The technological aspect of healthcare architecture has been influenced for several years by three major factors. The first is linked to the necessity of providing safety and security in the environment of elevated epidemiological risk. The second concerns the need for incorporating advanced technology...
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The Contemporary aspects of revitalization of the buildings and the port areas
PublikacjaPort cities are the forefront of globalization. The continued growth of international trade of goods and services has now played a major role in shaping the economic and social world. Strategies for mutual cooperation and follow-up between countries, cities and regions are increasingly complex. On the one hand it brings profits, on the other leads to destabilization and the need for transformation and constant modernization. Port...
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FACES OF MODERNISM - URBAN PLANNING OF SOCIAL HOUSING ESTATES IN GDANSK AND HAMBURG-ALTONA
PublikacjaThe paper aims to compare the modernistic social housing estates built during the interwar period in the Free City of Gdansk and in Altona, the small neighbour of Hamburg. The comparison is based on the analysis of the factors, which significantly affected the decisions regarding spatial transformations and the development of both cities in that time. These factors include primarily: poor living conditions, resulting from the explosive...
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Improved finite element method for flow, heat and solute transport of Prandtl liquid via heated plate
PublikacjaIn the current study, a vertical, 3D-heated plate is used to replicate the generation of heat energy and concentration into Prandtl liquid. We discuss how Dufour and Soret theories relate to the equations for concentration and energy. In order to see how efectively particles, interact with heat and a solvent, hybrid nanoparticles are used. It does away with the phenomena of viscous dissipation and changing magnetic felds. The motivation...
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Epoxy/Ionic Liquid-Modified Mica Nanocomposites: Network Formation–Network Degradation Correlation
PublikacjaWe synthesized pristine mica (Mica) and N-octadecyl-N’-octadecyl imidazolium iodide (IM) modified mica (Mica-IM), characterized it, and applied it at 0.1–5.0 wt.% loading to prepare epoxy nanocomposites. Dynamic differential scanning calorimetry (DSC) was carried out for the analysis of the cure potential and kinetics of epoxy/Mica and epoxy/Mica-IM curing reaction with amine curing agents at low loading of 0.1 wt.% to avoid particle...
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The role of the combined nitrogen-sulfur-carbon cycles for efficient performance of anammox-based systems
PublikacjaThe combined anammox/mixotrophic denitrification process was conducted in two granular sequencing batch reactors (SBRs) during a 200-day operation. Both reactors were fed with synthetic medium, but SBR2 was enriched with additional sulfate (SO4 2 ) which influenced sulfate reduction ammonium oxidation (SRAO) and heterotrophic reduction of SO4 2 by sulfate reducing bacteria. It was hypothesized that the addition of SO4 2 could...
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Covalent DNA modification by products of myrosinase catalysed glucosinolate degradation in cell-free system
PublikacjaThe bioactive phytochemicals found in Brassica vegetables belonging to glucosinolates (GLS) and especially the products of their degradation isothiocyanates (ITC) and indoles are regarded as the most promising cancer chemopreventive compounds. These secondary metabolites constitute defence system repelling or preventing the development of agrophages attacking brassica plants. The antibiological properties of these compounds suggest...