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Wyniki wyszukiwania dla: growth inhibition potential
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Potential clinical application of serum proteome mass spectrometry analyses in breast cancer patients diagnosis and management
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Analysis of Let-7 Family miRNA in Plasma as Potential Predictive Biomarkers of Diagnosis for Papillary Thyroid Cancer
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Variations in the near-surface atmospheric electric field at high latitudes and ionospheric potential during geomagnetic perturbations
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Sporothrix schenckii: purification and partial biochemical characterisation of glucosamine-6-phosphate synthase, a potential antifungal target
PublikacjaW artykule opisano izolację i charakterystykę właściwości natywnego enzymu, syntazy GlcN-6-P z komórek dimorficznego grzyba patogennego Sporothrix schenckii. Masę cząsteczkową enzymu natywnego określono na 350 kDa, a enzymu zdenaturowanego na około 79 kDa, co sugeruje homotetrameryczną strukturę białka. Wartość punktu izoelektrycznego wyniosła 6,26; wyznaczono także parametry kinetyczne katalizowanej reakcji. Aktywność enzymu była...
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Sonochemical synthesis of rosuvastatin based novel 3-methyleneisoindolin-1-one derivatives as potential anticancer agents
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Effect of the Yerba mate (Ilex paraguariensis) brewing method on the content of selected elements and antioxidant potential of infusions
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Pinus Species as Prospective Reserves of Bioactive Compounds with Potential Use in Functional Food—Current State of Knowledge
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Antioxidant potential of various solvent extract from Morus alba fruits and its major polyphenols composition
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Polyurethanes Crosslinked with Poly(vinyl alcohol) as a Slowly-Degradable and Hydrophilic Materials of Potential Use in Regenerative Medicine
PublikacjaNovel, slowly-degradable and hydrophilic materials with proper mechanical properties and surface characteristics are in great demand within the biomedical field. In this paper, the design, synthesis, and characterization of polyurethanes (PUR) crosslinked with poly(vinyl alcohol) (PVA) as a new proposition for regenerative medicine is described. PVA-crosslinked PURs were synthesized by a two-step polymerization performed in a solvent...
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Novel electrogravimetric biosensors for the ultrasensitive detection of plasma matrix metalloproteinase-2 considered a potential tumor biomarker
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Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
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Investigating the potential influence of biochar and traditional organic amendments on the bioavailability and transfer of Cd in the soil–plant system
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Investigation of DPPC effect on SiO2 particles and in the presence of phospho(lipases) by zeta potential and effective diameter measurements
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Investigations of DPPC effect on Al2O3 particles in the presence of (phospho)lipases by the zeta potential and effective diameter measurements
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Potential Use of Silica Nanoparticles for the Microbial Stabilisation of Wine: An In Vitro Study Using Oenococcus oeni as a Model
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Susceptibility to Oxidation of Selected Freshwater Fish Species Lipids as a Potential Source of Fish Oil in Dietary Supplements
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A Novel Method of Endotoxins Removal from Chitosan Hydrogel as a Potential Bioink Component Obtained by CO2 Saturation
PublikacjaThe article presents a new approach in the purification of chitosan (CS) hydrogel in order to remove a significant amount of endotoxins without changing its molecular weight and viscosity. Two variants of the method used to purify CS hydrogels from endotoxins were investigated using the PyroGene rFC Enzymatic Cascade assay kit. The effect of the CS purification method was assessed in terms of changes in the dynamic viscosity of...
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Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes
PublikacjaNew promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groupsincluding 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imi-dazoacridinone and triazoloacridinone derivatives with 1-nitroacridine compounds linked with anaminoalkyl chain. Cytotoxicity screening revealed the high potency of these compounds against severaltumor cell lines. Particularly, imidazoacridinone-1-nitroacridine...
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A multi‑criteria approach to investigate spatial distribution,sources, and the potential toxicological effect of polycyclic aromatic hydrocarbons (PAHs) in sediments of urban retention tanks
PublikacjaBottom sediments deposited in retention tanks (RTs) located on two urban streams (Oliwski and Strzyza) in the central part of Gdansk (Poland) were analysed for polycyclic aromatic hydrocarbons’ (PAHs) content. PAHs were extracted from samples with methylene chloride, then the extracts were subjected to clean-up applying the solid phase extraction (SPE) method. Quantitative and qualitative determination of 16 PAHs was performed...
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Mirosław Andrusiewicz prof. dr hab. n. med. i n. o zdr.
OsobyPosiadane dyplomy, stopnie naukowe lub artystyczne ̶ stopień doktora habilitowanego nauk medycznych (dyscyplina biologia medyczna) z dnia 4 grudnia 2017 r. Tytuł osiągnięcia naukowego: „Analiza wybranych genów związanych z przebiegiem zmian patologicznych w komórkach wywodzących się z żeńskich wewnętrznych narządów płciowych”; Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II; recenzenci: Prof....
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David Chiavacci, Simona Grano, Julia Obinger (eds.), Civil Society and the State in Democratic East Asia: Between Entanglement and Contention in Post High Growth
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Effect of silver/copper and copper oxide nanoparticle powder on growth of Gram-negative and Gram-positive bacteria and their toxicity against the normal human dermal fibroblasts
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Extracellular matrix metalloproteinase inducer (EMMPRIN) expression correlates positively with active angiogenesis and negatively with basic fibroblast growth factor expression in epithelial ovarian cancer
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Contrasting effects of biochar, compost and farm manure on alleviation of nickel toxicity in maize (Zea mays L.) in relation to plant growth, photosynthesis and metal uptake
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The metabolic profiles of pterin compounds as potential biomarkers of bladder cancer—Integration of analytical-based approach with biostatistical methodology
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Potential for Prebiotic Stabilized Cornus mas L. Lyophilized Extract in the Prophylaxis of Diabetes Mellitus in Streptozotocin Diabetic Rats
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Whey Proteins as a Potential Co-Surfactant with Aesculus hippocastanum L. as a Stabilizer in Nanoemulsions Derived from Hempseed Oil
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Optical properties of a series of pyrrolyl-substituted porphyrazines and their photoinactivation potential against Enterococcus faecalis after incorporation into liposomes
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N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H3 receptor and cancer resistance proteins
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Preparation and characterization of dummy-template molecularly imprinted polymers as potential sorbents for the recognition of selected polybrominated diphenyl ethers
PublikacjaThe main aim of this work was to conduct the preliminary/basic research concerning the preparation process of a new dummy molecularly imprinted polymer (DMIP) materials. Developed DMIPs were proposed as a sorption material in solid-phase extraction (SPE) technique for recognition of selected low mass polybrominated diphenyl ethers (PBDEs) e PBDE-47 and PBDE-99. Four new DMIPs were synthesized employing bulky polymerization technique...
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INDICES FOR ASSESSING POTENTIAL ENVIRONMENTAL HAZARD FROM FUTURE SHIP SCRAPPING PROCESS, DETERMINABLE IN SHIP DESIGN STAGE
PublikacjaThis paper shortly presents the issue of utilization of ships after their withdrawal from service. Information on number of floating units liquidated in previous years was presented. Hazards to the environment , health and life of workers employed in the Far East ship scrapping yards operating on the beaches, were indicated. Then, the most important rules which have to make the ship recycling process safe were referred to. This...
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Biological Control Potential of Native Entomopathogenic Nematodes (Steinernematidae and Heterorhabditidae) against Mamestra brassicae L. (Lepidoptera: Noctuidae)
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In silico studies and β-cyclodextrin mediated neutral synthesis of 4-oxo-4,5,6,7-tetrahydroindoles of potential biological interest
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The role of fine‑needle aspiration biopsy (FNAB) in the diagnostic management of parotid gland masses with emphasis on potential pitfalls
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A novel analytical approach in the assessment of unprocessed Kaffir lime peel and pulp as potential raw materials for cosmetic applications
PublikacjaVolatile fraction of fruits is a rich source of bioactive and aroma compounds, which can be used in the cosmetics industry after meeting relevant criteria. This is particularly evident in citrus fruits, especially in Citrus hystrix, in which the headspace consists mainly of terpenes. Due to the insufficient sensitivity of analytical methods, essential oils are used in investigations in contrast to fresh fruits. Therefore, a novel...
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Preliminary study on suitability of ionic liquids as potential passive-sampling media of polyaromatic-hydrocarbon (PAH) analyses in water
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Proteomic profile of melanoma cell‐derived small extracellular vesicles in patients’ plasma: a potential correlate of melanoma progression
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Estimation of Potential Leakage from Dumped Chemical Munitions in the Baltic Sea Based on Two Different Modelling Approaches
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Pd-catalysed general access to 7-membered N/O-heterocyclic compounds as potential agents against inflammation
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Optimization of the UNRES Force Field by Hierarchical Design of the Potential-Energy Landscape. 3. Use of Many Proteins in Optimization
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A field study investigating the potential use of phosphorus combined with organic amendments on cadmium accumulation by wheat and subsequent rice
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Bioavailability evaluation, uptake of heavy metals and potential health risks via dietary exposure in urban-industrial areas
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Central and Eastern European States from an International Perspective: Economic Potential and Paths of Participation in Global Value Chains
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Model yeast as a versatile tool to examine the antioxidant and anti-ageing potential of flavonoids, extracted from medicinal plants
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Yeast as a model to analyse the oxidative stress against acetic acid and anti-aging potential of Rice Flavonoids proceeding
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Cadmium and lead content in gluten and gluten-free bread available on the Polish market – potential health risk to consumers
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Potential of Waste Biomass from the Sugar Industry as a Source of Furfural and Its Derivatives for Use as Fuel Additives in Poland
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Antioxidant potential, mineral composition and inhibitory effects of conifer needle extract on hyaluronidase - prospects of application in functional food
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The potential of the application of biodegradable and non‐toxic base oils for the formulation of gear oils — model and component scuffing tests
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Potential of novel atomic emission techniques as a tool for investigation of the possibilities of using industrial waste as additives in construction materials
PublikacjaNowadays, due to the global ecological crisis and ways to prevent a climate disaster, more and more attention is paid to green techno-logies and green Chemistry, which are part of the so-called “The Green Deal.” The main assumption is the optimization of the processes of producing necessary goods and the implementation of methods of managing postproduction waste in the least environmentally harmful manner. In the presented research,...