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Wyniki wyszukiwania dla: REPEATED SEQUENCES
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Repeated Intra-Articular Administration of Platelet-Rich Plasma (PRP) in Temporomandibular Disorders: A Clinical Case Series
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Evaluation of the mechanical strength and protective properties of polycarbonate toecaps subjected to repeated impacts simulating workplace conditions
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Inhibitory activity of double‐sequence analogues of trypsin inhibitor SFTI‐1 from sunflower seeds: an example of peptide splicing
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B-GALACTOSIDASE ARTHROBACTER SP. 32cB - OBTAINING THE GENE SEQUENCE, CONSTRUCTION OF THE EXPRESSION SYSTEM, BIOSYNTHESIS AND BIOCHEMICAL CHARACTERIZATION OF THE ENZYME
PublikacjaINTRODUCTION: β-Galactosidase is an enzyme which catalyzes the hydrolysis of O glycosidic bond in β-galactosides. Another activity of β galactosidase is a transglycosylation activity. The main industrial use of this protein is the hydrolysis of lactose in milk in a cooling conditions. Synthesis of galactooligosaccharides, which are mostly used as a prebiotics added to some foods or available as dietary supplements, is only one...
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Performance of the Direct Sequence Spread Spectrum Underwater Acoustic Communication System with Differential Detection in Strong Multipath Propagation Conditions
PublikacjaThe underwater acoustic communication (UAC) operating in very shallow-water should ensure reliable transmission in conditions of strong multipath propagation, significantly disturbing the received signal. One of the techniques to achieve this goal is the direct sequence spread spectrum (DSSS) technique, which consists in binary phase shift keying (BPSK) according to a pseudo-random spreading sequence. This paper describes the DSSS...
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Identification of evolutionary conserved DNA sequence and corresponding S21 ribosomal protein region for diagnostic purposes of all Borrelia spirochetes
PublikacjaIt is still under investigation, whether all Borrelia sp. causing Lyme borreliosis and other diseases are already identified and properly classified as human pathogens. For this reason, it is of great importance to develop a diagnostic ELISA test that detects all Borrelia sp. The aim of this study was to identify conserved DNA and protein regions present in all currently known Borrelia sp. In experimental studies 31 available Borrelia...
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Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes
PublikacjaSelf-assembling peptides can be used for the regeneration of severely damaged skin. They can act as scaffolds for skin cells and as a reservoir of active compounds, to accelerate scarless wound healing. To overcome repeated administration of peptides which accelerate healing, we report development of three new peptide biomaterials based on the RADA16-I hydrogel functionalized with a sequence (AAPV) cleaved by human neutrophil elastase...
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Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes
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Conserved motifs of MutL proteins
PublikacjatThe MutL protein is best known for its function in DNA mismatch repair (MMR). However, there isevidence to suggest that MutL is not only the linker connecting the functions of MutS and MutH in MMR,but that it also participates in other repair systems, such as Very Short Patch (VSP), Base Excision (BER)and Nucleotide Excision Repair (NER). This study set out to identify the most highly conserved aminoacid sequence motifs in MutL...
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Chromatic cost coloring of weighted bipartite graphs
PublikacjaGiven a graph G and a sequence of color costs C, the Cost Coloring optimization problem consists in finding a coloring of G with the smallest total cost with respect to C. We present an analysis of this problem with respect to weighted bipartite graphs. We specify for which finite sequences of color costs the problem is NP-hard and we present an exact polynomial algorithm for the other finite sequences. These results are then extended...
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Design of Experiments in metabolomics-related studies: An overview
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Medication-Related Osteonecrosis of the Jaw—A Continuing Issue
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Raman spectroscopic investigation of blood and related materials
PublikacjaThis paper reports preliminary studies on use of Raman spectroscopy for investigation of blood. High quality blood spectra were recorded in-vitro with excitation wavelengths of 830 nm. Because of complex composition of the blood as well as by light attenuation and scattering in the tissues, spectra set up from wide, low-intensive Raman bands and intensive optical background. To get information about origin of bands in Raman spectra...
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Integrity level verification for safety-related functions
PublikacjaThis article describes methods for safety integrity level (SIL) verification of safety-related functions with regard to probabilistic criteria given international standards IEC 61508 and IEC 61511. These functions are to be realized using the electrical, electronic and programmable electronic (E/E/PE) systems or safety instrumented systems (SIS). Some methods are proposed for quantitative probabilistic modelling taking into account...
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Efficacy of coping with work-related stress by firemen
PublikacjaThe aim of this study was efficacy of coping with work-related stress by firemen with reference to subjective health evaluation. Theoretical model of process of stress by Lazarus was applied. The group consistent of 230 line-duty firemen. Participation in traumatic events and sense of coherence both directly and indirectly, by stress, affected the health among firemen. In stress confrontation a wider array of task and emotional...
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Domination-Related Parameters in Rooted Product Graphs
PublikacjaAbstract A set S of vertices of a graph G is a dominating set in G if every vertex outside of S is adjacent to at least one vertex belonging to S. A domination parameter of G is related to those sets of vertices of a graph satisfying some domination property together with other conditions on the vertices of G. Here, we investigate several domination-related parameters in rooted product graphs.
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Efficiency of new method of removing noisy background from the sequence of MRI scans depending on structure elements used to morphological processing
PublikacjaPrzedstawiono nową metodę usuwania zaszumionego tła z sekwencji skanów MRI. Każdy skan zawiera przekrój mózgu i tło, oba zaszumione. Tło należy wykluczyć z dalszej analizy. Eliminacji tła dokonano dzięki zastosowaniu opisanego algorytmu wykorzystującego podstawowe operacje morfologiczne: dylację, erozję, otwarcie i zamknięcie do uprzednio zbinaryzowanych zbiorów MRI. Zaprezentowano wyniki przetwarzania otrzymane dla różnych kształtów...
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Reducing the number of periodic points in the smooth homotopy class of a self-map of a simply-connected manifold with periodic sequence of Lefschetz numbers
PublikacjaLet f be a smooth self-map of an m-dimensional (m >3) closed connected and simply-connected manifold such that the sequence of the Lefschetz num- bers of its iterations is periodic. For a fixed natural r we wish to minimize, in the smooth homotopy class, the number of periodic points with periods less than or equal to r. The resulting number is given by a topological invariant J[f] which is defned in combinatorial terms and is...
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Complete Nucleotide Sequence of the pCTX-M3 Plasmid and Its Involvement in Spread of the Extended-Spectrum β-Lactamase GeneblaCTX-M-3
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Relation of the polymorphism of cyp51A sequence and the susceptibility of Aspergillus fumigatus isolates to triazoles determined by commercial gradient test (Etest) and by reference methods
PublikacjaThe aim of this study was to evaluate the accuracy of commercial gradient test (Etest) in the detection of triazole resistant Aspergillus fumigatus isolates using reference microdilution methods and the analysis of sequences of the cyp 51A gene. The study was performed on twenty clinical isolates which were identified as Aspergillus fumigatus based on the DNA sequences of the ITS1-2 fragment of ribosomal DNA and the β-tubulin gene,...
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Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors
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Spectroscopic studies on physicochemical properties of selected unsymmetrical bisacridine derivatives and NMR analysis of their interactions with the model sequence Pu22 aided by molecular dynamics
PublikacjaIn recent years, new promising acridine derivatives have appeared, belonging to the unsymmetrical bisacridines (UAs) family with high anticancer activity. Both their physicochemical properties and their mechanism of action at the molecular level have not been thoroughly analyzed so far. Four derivatives were selected for the study, termed as: C-2028, C-2041, C-2045 and C-2053. The first aim of this work was to determine the protonation...
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Assessment of cavitation erosion damage of laser remelted the SUPERSTON alloy
PublikacjaW artykule przedstawiono wpływ obróbki laserowej w warunkach kriogenicznych na mikrostrukturę stopu SUPERSTON po badaniach kawitacyjnych. Badania odporności kawitacyjnej przeprowadzono na stanowisku z wirującą tarczą w IMP PAN Gdańsk. Określono kinetykę ubytku masy próbek podczas testu kawitacyjnego dla stopu odlanego i nadtopionego laserowo.
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Fragmentomic analysis of biopeptides in silico released from milk proteins
PublikacjaThe fragmentomic-assisted method was employed to predict the biological potential of peptides derived from milk proteins hydrolyzed by papain and bromelain. Firstly, protein sequences were acquired from the BIOPEP-UWM database and then hydrolyzed by the above enzymes using a BIOPEP-UWM tool called “Enzyme(s) action”. The released peptides were defined as parent peptides and further analyzed for the presence of shorter peptidic...
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The Transformation Revealed Concept of Smart City Application in Urban Planning
PublikacjaThe purpose of this paper is to present the findings of research conducted to reveal a smart city application concept in urban planning. The method is discussed in the context of case studies of smart city concepts in Malaysian states namely Johor, Penang and Selangor, with the efficient and effective state for implementation and application in urban planning being selected. The case study method was utilised to demonstrate the...
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The study of polish consumer's online brand-related activities
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Modeling of behavior of organic pollutants in aquatic and related ecosystems
PublikacjaW pracy omówiono możliwości wykorzystania różnych modeli do opisu zjawisk migracji oraz przemian w środowisku wodnym ksenobiotyków z grupy trwałych zanieczyszczeń organicznych (TZO). Przedstawiono charakterystykę zarówno modeli otwartych, jak i zamkniętych w warunkach ustalonych, jak i w warunkach nierównowagowych.
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Tackling age-related disease: time for a step forward
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Overview of problems in mathematics related analysis of capital markets
PublikacjaCelem pracy jest przegląd zjawisk i problemów w analizie rynków kapitałowych metodami matematyki. Zdefiniowano główny cel analiz rynkowych. Przedstawiono stosowane podejście w analizie rynków. Przedyskutowano podejście stochastyczne i deterministyczne. Kolejno przedstawiono zjawiska sprężeń zwrotnych w rynkach. Na koniec przedstawiono, specyficzne dla rynków zjawiska, które mają duży wpływ na zniekształcenie wyników analizy.
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Editorial “Nutrition and Dietary Intake for Liver-Related Diseases”
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Modeling Online Buyers’ Preferences Related to Webpages Layout
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Acoustics-related aspects of historic interior modernization projects
PublikacjaThe paper presents three historic interiors in which modernization projects have been carried out having an important impact on their acoustic qualities. Two of the described case studies are positive examples of solving the problem of a natural contradictions between modern technical standards and strict discipline imposed by the heritage conservation system. On the other hand, the effect of neglecting the acoustic needs when...
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Static puncture tests of geotextiles and geotextile - related prodcts
PublikacjaW artykule omówiono dwa rodzaje przebicia statycznego geotekstyliów i wyrobów pokrewnych: standardowe badanie CBR zgodnie z normą EN ISO 12236 i nowe metody opracowywane przez CEN TC 189 w ramach projektu normy PrEN 189066. Procedury wykonywania badań są podobne, różnią się: tłokiem obciążającym, metodą podparcia materiału, wypełnieniem cylindra oraz zastosowanym materiałem geosyntetycznym.
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Assessment of safety - related systems in industrial hazardous plants
PublikacjaPrzedstawiono problemy związane z określaniem bezpieczeństwa funkcjonalnego systemów przemysłowych, w oparciu o standard IEC 61508. Wykorzystując informacje zawarte w cytowanym standardzie opisujemy metody określenia wymaganych poziomów zabezpieczeń dla instalacji przemysłowej. Wyjaśniamy znaczenie poziomów SIL. Poddano dyskusji procedurę poprawnego określania poziomów bezpieczeństwa systemów składających się z elementów o...
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Upward convergence patterns in chosen environmental-related SDGs
PublikacjaSustainable development is a challenge facing humanity. EU countries not only strive to reach their specific objectives, but they also work collaboratively towards shared goals. There is a need to balance synergies and compromises to address these objectives effectively. When discussing countries' development and people's well-being, one often focuses on socio-economic development. However, it is crucial not to overlook the environmental...
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Overview of problems in mathematics related analysis of capital markets
PublikacjaCelem pracy jest przedstawienie niektórych zjawisk w rynkach kapitałowych i problemów z ich analizą przy użyciu metod matematyki i nauk od niej pochodnych. Na wstępie określono cel analizy rynków. Kolejno przedstawiono historyczne podejścia do problemu ich analizy. Pokrótce przedyskutowano zagadnienie postrzegania rynków w kategoriach deterministycznych jak i stochastycznych. Następnie wskazano na istnienie sprzężeń zwrotnych w...
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Low-energy interactions related to atmospheric and extreme conditions
PublikacjaThis Topical Issue, entitled “Low-Energy Interactions Related to Atmospheric and Extreme Conditions”, showcases a collection of eighteen articles that reported recent theoretical and experimental findings pertaining to the following topics: – low-energy interactions of charged particles (electrons [1–7], protons [8], positrons [9]), and photons [10] with atoms and molecules of biological [1–4,7,8], astrochemical [10], industrial,...
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Repeated bouts of exhaustive exercise increase circulating cell free nuclear and mitochondrial DNA without development of tolerance in healthy men
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Influence of amino acid sequence on the interaction of short peptides containing 3-[2-(9-anthryl)benzoxazol-5-yl]-alanine with β-cyclodextrin
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Novel Highly Thermostable Endolysin from Thermus scotoductus MAT2119 Bacteriophage Ph2119 with Amino Acid Sequence Similarity to Eukaryotic Peptidoglycan Recognition Proteins
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Improvement of time difference of arrival measurements resolution by using fractional delay filters in a direct sequence-code division multiple access radionavigation system
PublikacjaThis study presents a method of improving time measurements resolution in a direct sequence-code division multiple access receiver by using a fine code tracking loop based on fractional delay filtering of a despreading sequence. It briefly describes the structure of a generic digital code tracking loop and the proposed modification which allows to measure time difference of arrival values with the subsample resolution, together...
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TspGWI, a thermophilic class-IIS restriction endonuclease from Thermus sp.,recognizes novel asymmetric sequence 5´-ACGGA(N11/9)-3
PublikacjaA novel prototype class-IIS restriction endonuclease, TspGWI, was isolated from the thermophilic bacterium Thermus sp. GW. The recognition sequence and cleavage positions have been established: TspGWI recognizes the non-palindromic 5-bp sequence 5′-ACGGA-3′ and cleaves the DNA 11 and 9 nt downstream in the top and bottom strand, respectively. In addition, an accompanying endonuclease, TspGWII, an isoschizomer of Pst I, was found...
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An insight into the mixed quantum mechanical-molecular dynamics simulation of a ZnII-Curcumin complex with a chosen DNA sequence that supports experimental DNA binding investigations
PublikacjaAn important aspect of research pertaining to Curcumin (HCur) is the need to arrest its degradation in aqueous solution and in biological milieu. This may be achieved through complex formation with metal ions. For this reason, a complex of HCur was prepared with ZnII, that is not likely to be active in redox pathways, minimizing further complications. The complex is monomeric, tetrahedral, with one HCur, an acetate and a molecule...
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On the Origin of Protein Superfamilies and Superfolds
PublikacjaDistributions of protein families and folds in genomes are highly skewed, having a small number of prevalent superfamiles/superfolds and a large number of families/folds of a small size. Why are the distributions of protein families and folds skewed? Why are there only a limited number of protein families? Here, we employ an information theoretic approach to investigate the protein sequence-structure relationship that leads to...
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Guaranteeing Threshold Attendance of W/WSAN nodes in a reverted security paradigm
PublikacjaWe consider a Wireline/Wireless Sensor and Actor Network composed of sensor/actor nodes and a data sink/command center (DSCC). Each node controls a generic device that can be in- or out-of-service, corresponding to the ENABLED or DISABLED node state. The node senses the device's intention to change state, and notifies and/or requests the DSCC for authorization to act upon the device. Motivated by requirements for critical infrastructures...
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Histopathological examination of tissue resected during bariatric procedures – to be done or not to be done?
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Practises of entrepreneurs from SMEs sector related to risk management
PublikacjaWyniki badań MSP dotyczące praktyk ubezpieczeniowych. Właściciele małych i średnich przedsiębiorstw wykazują się niewielką znajomością procesów zarządzania ryzykiem. Ich działania na rzecz ograniczania ryzyk w działalności gospodarczej dają podstawę do oceny poziomu świadomości ubezpieczeniowej tej grupy przedsiebiorców.
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Functionalized polypyrroles. New molecular materials for electrocatalysis and related applications
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Obesity-related hypertension: relevance of vascular responses to mental stress
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Selected issues related to the research on a hybrid three-wheeler for the disabled
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