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Metabolism of antitumor 9-amino-1-nitroacridine derivatives in HepG2 cells and its influence on cytochrome P450 isoenzymes
PublikacjaCelem przeprowadzonych badań było określenie wpływu pochodnych C-857 i C-1748 na poziom enzymów cytochromu P450 w powiązaniu z kinetyką metabolizmu badanych związków. Eksperymenty zostały przeprowadzone na komórkach ludzkiego nowotworu wątroby HepG2. Uzyskane wyniki metodą Western blotting wykazały, że za metaboliczną transformacje pochodnych C-857 i C-1748 odpowiada izoenzym CYP3A4.Analiza metabolitów (Western blotting, HPLC)...
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Systematic Study of Hydration Patterns of Phosphoric(V) Acid and Its Mono-, Di-, and Tripotassium Salts in Aqueous Solution
PublikacjaSpektroskopia oscylacyjna FTIR w zakresie drgania OD cząsteczki HDO została zastosowana do zbadania różnych form fosforanów w kolejności malejącego stopnia protonacji: H3PO4, KH2PO4, K2HPO4, K3PO4. HDO rozcieńczona izotopowo w H2O została otrzymana przez dodanie odpowiednich ilości wody ciężkiej (D2O) do roztworów w wodzie zwykłej. Do wyizolowania widm HDO zaburzonej przez substancję rozpuszczoną zastosowano metodę widm różnicowych....
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Rapid and simplified synthesis of [ 18 F]Fluoromisonidazole and its use in PET imaging in an experimental model of subarachnoid hemorrhage
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Tissue fixed with formalin and processed without paraffin embedding is suitable for imaging of both peptides and lipids by MALDI-IMS
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Emotional Distress Associated with Surgical Treatment and its Relationship with Coping Profiles Among Chronically ill Older Patients
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Cost of Equity of Coal-Fired Power Generation Projects in Poland: Its Importance for the Management of Decision-Making Process
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Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
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Measurements and calculation of self inductance of testing coils used in physical transformer model construction and its frequency analysis
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Carotenoid Content in Breastmilk in the 3rd and 6th Month of Lactation and Its Associations with Maternal Dietary Intake and Anthropometric Characteristics
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Non-disjoint Decomposition Using r-admissibility and Graph Coloring and Its Application in Index Generation Functions Minimization
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The motif EXEXXXL in the cytosolic tail of the secretory human proprotein convertase PC7 regulates its trafficking and cleavage activity
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Analysis of different tillage implements with respect to reduced fuel consumption, tractor operating speed and its wheel slippage
PublikacjaNowadays the prices of agricultural farm produced products are increasing with ant-speed and the prices of input for raising crops are increasing with rocket-speed. Therefore, there is a dire need to conduct some important studies to innovate the techniques which can lower the costs of crop production. In this context, this study was conducted to evaluate the consumption of fuel at different tillage implements, tractor operating...
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Structural Change in New Member States (1995–2005): Shift–Share Analysis of Productivity Growth and its Determinants
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The effect of the annual growth and the late wood share upon density of the Polish pine wood as a function of its origin
PublikacjaW artykule przedstawiono zróżnicowanie gęstości polskiego drewna sosnowego (Pinus sylvestris L.) w zależności od udziału drewna późnego w przyroście rocznym z uwzględnieniem krainy pochodzenia drewna. Wspomniane zróżnicowanie jest w istotne statystycznie w skali globalnej oraz dla większości miejsc pochodzenia. Pomiar gęstości wykonano przy użyciu metody stereometrycznej. Metoda ta polegała na określeniu objętości pryzmy poprzez...
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Distributed System for Monitoring of the Large Scale Infrastructure Structures Based on Analysis of Changes of its Static and Dynamic Properties
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Potential of Waste Biomass from the Sugar Industry as a Source of Furfural and Its Derivatives for Use as Fuel Additives in Poland
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Observing its long-term effects on a short-term, multi-day evaluation of the effectiveness of hearing aid use
PublikacjaThe main objective of the research study was to develop a method for evaluating the effectiveness of hearing protection with hearing aids tailored to the needs and prevailing conditions in the acoustic environments where the elderly most often reside. The method was also intended to estimate the benefits of hearing aids and allow prediction of such an effect based on a short-term trial. It is noteworthy that a short-term evaluation...
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Development of cluster analysis methodology for identification of model rainfall hyetographs and its application at an urban precipitation field scale
PublikacjaDespite growing access to precipitation time series records at a high temporal scale, in hydrology, and particularly urban hydrology, engineers still design and model drainage systems using scenarios of rainfall temporal distributions predefined by means of model hyetographs. This creates the need for the availability of credible statistical methods for the development and verification of already locally applied model hyetographs....
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One-step converting biowaste wolfberry fruits into hierarchical porous carbon and its application for high-performance supercapacitors
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Compositional characteristics and nutritional quality of European beaver (Castor fiber L.) meat and its utility for sausage production
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On the Nonlinea Distortions of Sound and its Coupling with Other Modes in a Gasesous Plasma with Finite Electric Conductivity in a Magnetic Field
PublikacjaNonlinear phenomena of the planar and quasi-planar magnetoacoustic waves are considered. We focus on deriving of equations which govern nonlinear excitation of the non-wave motions by the intense sound in initially static gaseous plasma. The plasma is treated as an ideal gas with finite electrical conductivity permeated by a magnetic field orthogonal to the trajectories of gas particles. This introduces dispersion of a flow. Magnetoacoustic...
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The hydration of the protein stabilizing agents: trimethylamine-N-oxide, glycine and its N-methylderivatives - the volumetric and compressibility studies
PublikacjaThe densities at T = (288.15, 293.15, 298.15, 303.15, and 308.15) K and sound velocities at T = 298.15 K have been measured for aqueous solutions of trimethylamine-N-oxide, glycine, N-methylglycine (sarcosine), N,N-dimethylglycine, N,N,N-trimethylglycine (betaine). From these data the apparent molar volumes, VΦ, the apparent molar isentropic compressions, KS,Φ, and the solvation numbers of solutes have been determined. The concentration...
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Isolation of the GFA1 gene encoding glucosamine-6-phosphate synthase of Sporothrix schenckii and its expression in Saccharomyces cerevisiae
PublikacjaGlucosamine-6-phosphate synthase (GlcN-6-P synthase) is an essential enzyme involved in cell wall biogenesis that has been proposed as a strategic target for antifungal chemotherapy. Here we describe the cloning and functional characterization of Sporothrix schenckii GFA1 gene which was isolated from a genomic library of the fungus. The gene encodes a predicted protein of 708 amino acids that is homologous to GlcN-6-P synthases...
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Multiparameter analysis of the Barkhausen noise signal and its application for the assessment of plastic deformation level in 13HMF grade steel
PublikacjaArtykuł przedstawia wyniki wieloparametrowej analizy właściwości sygnału szumu Barkhausena (BN). Poza powszechnie stosowanymi kwantyfikatorami sygnału szumu Barkhausena takimi jak amplituda, całka z obwiedni sygnału czy też wynikami analizy impulsowej sygnału proponujemy dodatkową analizę opartą na zmianach amplitudy prądu magnesującego. Jak się okazuje charakter zmian sygnału Barkhausena (w funkcji stopnia deformacji plastycznej)...
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Structural change in New Member States (1995-2005): shift-share analysis of productivity growth and its determinants
PublikacjaThe chapter focuses on the latest developments in ten New MemberStates (presented vis-à-vis EU-15countries), seen from the perspective of structural change and quality upgrading of their economic structures. In particular, recently released disaggregated labor statistics are used,allowing to analyse the process of labor reallocation and productivitychanges associated with inter-and intra-industrystructural change. Since the mid-1990s...
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Historic Urban Settings, LED Illumination and its Impact on Nighttime Perception, Visual Appearance, and Cultural Heritage Identity
PublikacjaMany cities, towns and villages around the world have adopted new Lighting Emitting Diode (LED) technology in order to save energy, operational and maintenance costs. While energy-efficient, these light sources have a critical effect on the appearance of historic sites at night and the technology has unique properties and numerous inherent drawbacks that present challenges to decision makers as well as inexperienced lighting...
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Stability Analysis of the Floating Offshore Wind Turbine Support Structure of Cell Spar Type During its Installation
PublikacjaThe article presents the results of selected works related to the wider subject of the research conducted at the Faculty of Ocean Engineering and Ship Technology of the Gdansk University of Technology, which concerns design and technology of construction, towing, and settlement on the seabed, or anchoring, of supporting structures for offshore wind farms. As a result of this research, several designs of this type of objects were...
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Vegetable derived-oil facilitating carbon black migration from waste tire rubbers and its reinforcement effect
PublikacjaThree dimensional chemically cross-linked polymer networks present a great challenge for recycling and reutilization of waste tire rubber. In this work, the covalently cross-linked networks of ground tire rubber (GTR) were degraded heterogeneously under 150 °C due to the synergistic effects of the soybean oil and controlled oxidation. The degradation mechanism was discussed using Horikx theory and Fourier transformation infrared...
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Endoscopic Videos Deinterlacing and On-Screen Text and Light Flashes Removal and Its Influence on Image Analysis Algorithms' Efficiency
PublikacjaIn this article, deinterlacing and removing on- screen text and light flashes methods on endoscopic video images are discussed. The research is intended to improve disease recognition algorithms' performance. In the article, four configurations of deinterlacing methods and another four configurations of text and flashes removal methods are described and examined. The efficiency of endoscopic video analysis algorithms is measured...
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Influence of Phosphorus Speciation on Its Chemical Removal from Reject Water from Dewatering of Municipal Sewage Sludge
PublikacjaThe aim of the presented research was the assessment of phosphorus speciation impact on the precipitation of phosphorus in reject water using Ca(OH)2. To achieve this, phosphorus speciation (organic and inorganic phosphorus in suspension and in dissolved form) in reject water that is produced during sludge dewatering, after methane digestion in wastewater treatment plants (WWTPs), was determined. This study covered the materials...
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Some Aspects of Shear Behavior of Soft Soil–Concrete Interfaces and Its Consequences in Pile Shaft Friction Modeling
PublikacjaThis paper examines the stiffness degradation and interface failure load on soft soil–concrete interface. The friction behavior and its variability is investigated. The direct shear tests under constant normal load were used to establish parameters to hyperbolic interface model which provided a good approximation of the data from instrumented piles. Four instrumented piles were used to obtain reference soil–concrete interface behavior....
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The Interaction of Heptakis (2,6-di-O-Methyl)-β-Cyclodextrin with Mianserin Hydrochloride and Its Influence on the Drug Toxicity
PublikacjaOne tetracyclic antidepressant, mianserin hydrochloride (MIA), has quite significant side effects on a patients’ health. Cyclodextrins, which are most commonly used to reduce the undesirable features of contained drugs within their hydrophobic interior, also have the potential to alter the toxic behavior of the drug. The present paper contains investigations and the characteristics of interaction mechanisms for MIA and the heptakis...
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Business continuity management framework for Industry 4.0 companies regarding dependability and security of the ICT and ICS/SCADA system
PublikacjaThis chapter addresses a business continuity management (BCM) framework for the Industry 4.0 companies including the organizational and technical solutions, regarding the dependability and security of the information and telecommunication technology (ICT), and the industrial control system (ICS) / supervisory control and data acquisition (SCADA) system. These technologies and systems play nowadays important roles in modern advanced...
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Students and Young Professionals of the IEEE IES in the Time of Information, Automation, and Energy Transformation [Students and Young Professionals News]
PublikacjaReports on IEEE IES Society student activities in year 2021.
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Spatial Distribution of Eucalyptus Plantation and its Impact on the Depletion of Groundwater Resources of Tehsil Swat Ranizai, District Malakand
PublikacjaNative to the continent of Australia, eucalyptus is a tall, evergreen tree belonging to the Myrtaceae family. Malakand district has the largest eucalyptus plantation in the province, covering an area of 22,071.29 ha. The present study aims to evaluate its impact on the groundwater table (GWT) in three selected union councils (UCs) of the study area, i.e., Agra, Totakan, and Kot. Both primary and secondary data support the study....
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Discrete element method simulations of fracture in concrete under uniaxial compression based on its real internal structure
PublikacjaThe paper describes experimental and numerical results of concrete fracture under quasi-static uniaxial compression. Experimental uniaxial compression tests were performed on concrete cubic specimens. Fracture in concrete was detected at the aggregate level by means of three non-destructive methods: three-dimensional X-ray microcomputed tomography, two-dimensional scanning electron microscope and manual two-dimensional digital...
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Salt saturated single-drop microextraction of malondialdehyde from human plasma before its determination by gas chromatography
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International Conference on Worldwide Computing and Its Applications
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International Symposium on Information Theory and Its Applications
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Simulation of the derecho event in Poland of 11th August 2017 using the WRF model and GFS data as initial conditions
Dane BadawczeThis series contains datasets related to the forecasting of a severe weather event, a derecho, in Poland on 11 August 2017. The simulations were conducted using the Weather Research and Forecasting (WRF) model version 4.2.1 with initial and boundary conditions from Global Forecast System (GFS). Simulation was performed for two starting hours: at 00:00...
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Ryszard Strzelecki prof. dr hab. inż.
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Porphyrazine with bulky 2-(1-adamantyl)-5-phenylpyrrol-1-yl periphery tuning its spectral and electrochemical properties
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Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
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ATP4A autoimmunity in pediatric patients with type 1 diabetes and its relationship to blood count, iron metabolism, and vitamin B12
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Influence of Polymorphisms in DNA Repair GenesXPD, XRCC1andMGMTon DNA Damage Induced by Gamma Radiation and its Repair in LymphocytesIn Vitro
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Air pollution in the places of Betula pendula growth and development changes the physicochemical properties and the main allergen content of its pollen
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Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives
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Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions—benign adenomas and inflammatory bowel disease
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Functional Similarities and Differences of an Archaeal Hsp70(DnaK) Stress Protein Compared with its Homologue from the Bacterium Escherichia coli
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Ibotenic acid lesion of the ventral hippocampus differentially affects dopamine and its metabolites in the nucleus accumbens and prefrontal cortex in the rat
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