Wyniki wyszukiwania dla: REGENERATIVE DRUGS

• Journal of Stem Cells & Regenerative Medicine

  Czasopisma

  ISSN: 0973-7154

• Sensing of anesthetic drugs in blood with Raman spectroscopy

  Publikacja

  • M. Wróbel
  • M. Gnyba
  • M. Szczerska
  • T. Myllylä
  • J. Smulko
  • I. Barman

  - Rok 2015

  A proof-of-concept study of a Raman spectroscopy-based approach for measuring the content of anesthesia drugs in blood is presented. Spectra of spiked blood from several patients exhibit prominent changes in regions associated with the drug.

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• CNS DRUGS

  Czasopisma

  ISSN: 1172-7047 , eISSN: 1179-1934

• DRUGS & AGING

  Czasopisma

  ISSN: 1170-229X , eISSN: 1179-1969

• PEDIATRIC DRUGS

  Czasopisma

  ISSN: 1174-5878 , eISSN: 1179-2019

• DRUGS OF TODAY

  Czasopisma

  ISSN: 1699-3993 , eISSN: 1699-4019

• Drugs in Context

  Czasopisma

  ISSN: 1745-1981

• Indian Drugs

  Czasopisma

  ISSN: 0019-462X

• Drugs and Clinic

  Czasopisma

  ISSN: 1674-5515

• Epigenetic inhibitor zebularine activates ear pinna wound closure in the mouse

  Publikacja

  • P. Sass
  • P. Sosnowski
  • J. Podolak-Popinigis
  • B. Górnikiewicz
  • J. Kamińska
  • M. Deptuła
  • E. Nowicka
  • A. Wardowska
  • J. Ruczyński
  • P. Rekowski... i 12 innych

  - EBioMedicine - Rok 2019

  Background:Most studies on regenerative medicine focus on cell-based therapies and transplantations.Small-molecule therapeutics, though proved effective in different medical conditions, have not been extensivelyinvestigated in regenerative research. It is known that healing potential decreases with development and devel-opmental changes are driven by epigenetic mechanisms, which suggests epigenetic repression of regenerativecapacity.Methods:We...

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• Human amniotic-fluid-derived stem cells: a unique source for regenerative medicine

  Publikacja

  • A. Bajek
  • J. Olkowska
  • N. Gurtowska
  • T. Kloskowski
  • M. Walentowicz-Sadlecka
  • P. Sadlecki
  • M. Grabiec
  • T. Drewa

  - EXPERT OPINION ON BIOLOGICAL THERAPY - Rok 2014

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• Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential

  Publikacja

  • B. Górnikiewicz
  • A. Ronowicz
  • M. Krzemiński
  • P. Sachadyn

  - BMC GENOMICS - Rok 2016

  Background The neonatal murine heart is able to regenerate after severe injury; this capacity however, quickly diminishes and it is lost within the first week of life. DNA methylation is an epigenetic mechanism which plays a crucial role in development and gene expression regulation. Under investigation here are the changes in DNA methylation and gene expression patterns which accompany the loss of regenerative potential. Results The...

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• Urban development and regeneration in Poland - contemporary issues

  Publikacja

  • P. Lorens

  - GeoScape - Rok 2010

  Artykuł obejmuje skrótowe omówienie współczesnych procesów rozwoju i rewitalizacji miast w Polsce. Zaprezentowano w nim zarówno procesy planowe jak i zachodzące spontanicznie, a także typologie obszarów poddawanym współczesnym procesom przekształceń

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• Places of worship, spiritual healing and urban regeneration

  Publikacja

  • M. Trojanowska

  - Urbanistica Informazioni - Rok 2014

  Many researchers demonstrated that it is possible to help people achieve mental and physical regeneration with proper architecture, urban and landscape planning. The term therapeutic landscapes could also be applied to places of worship, where people gather for spiritual healing and renewal. Public space that they offer is inclusively open to all. Addition- ally, they serve to reinvigorate the places where they are located. Shrines...

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• Sources of investment risk in urban regeneration projects

  Publikacja

  • M. Apollo
  • J. Brzezicka

  - Czasopismo Techniczne - Rok 2014

  The scope of the article includes multidimensional risk analysis of urban regeneration projects, whose base is to identify areas of its occurrence. Authors thoroughly analyze the sources of potential threats and attempts to answer the question, what is their contribution into overall urban regeneration’ investment risk. The target concept will be used to assess the level of investment risk at the stage of initiation, preparation...

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• Market Regeneration in Line with Sustainable Urban Development

  Publikacja

  • J. Borucka
  • P. Czyż
  • G. Gasco
  • W. M. Mazurkiewicz
  • D. Nałęcz
  • M. Szczepański

  - Sustainability - Rok 2022

  This article presents the study of the optimal design solutions for regeneration of marketplaces. It examines the design variants for the revitalisation of the marketplace, in particular, investment in their modernisation in order to find the most optimal model for transforming these public spaces to have a significant impact on the city’s development. The research is a comparative analysis of the implementation of regeneration...

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• Definition of urban regeneration projects in Russian cities

  Publikacja

  • A. Kiteleva

  - BIULETYN KOMITETU PRZESTRZENNEGO ZAGOSPODAROWANIA KRAJU PAN - Rok 2016

  Urban regeneration is extremely important process for Russian cities, which faced to the challenges of post-industrial economy. In an attempt, to explain needs of urban regeneration in Russian megacities author analyzed the social and economic trends and some historic features of Russian cities development. The article identified the key areas for regeneration such as the regeneration of historic core, the regeneration of the urban...

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• Machine learning applied to bi-heterocyclic drugs recognition

  Publikacja

  • M. Nowak
  • K. Nowak
  • M. Grzelczak
  • B. Szlachetko
  • L. Sterczewski
  • E. Plinski
  • P. Swiatek
  • M. Strzelecka
  • S. Plinska
  • W. Malinka

  - Rok 2017

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• Glucosinolates from lepidium peruvianum as potential antiamnestic drugs

  Publikacja

  • D. Tarabasz
  • D. Szwajgier
  • P. Szczeblewski
  • T. Laskowski
  • W. Płaziński
  • E. Baranowska-Wójcik
  • W. Kukula-Koch
  • H. O. Meissner

  - Rok 2022

  Lepidium peruvianum (maca) (Brassicaceae) is a naturally occurring plant mainly in the high Andes of Peru. In recent years, it has been intensively researched in terms of its influence on various diseases and towards health improvement. Alzheimer’s disease is an incurable disease that most often affects adults over the age of 60. As since 2003 the US Food and Drug Administration (FDA) did not approve any new drug for Alzheimer’s...

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• Ultimate biodegradability and ecotoxicity of orally administered antidiabetic drugs

  Publikacja

  • M. Markiewicz
  • C. Jungnickel
  • S. Stolte
  • A. Białk-Bielińska
  • J. Kumirska
  • W. Mrozik

  - JOURNAL OF HAZARDOUS MATERIALS - Rok 2017

  Hypoglycaemic pharmaceuticals are recently more and more frequently detected in the environment. In our previous study, we have shown that even though many of them undergo significant primary degradation some are transformed to stable products or undergo such transformation that a large part of the structure is still preserved. One of the main routes of elimination from wastewaters or surface waters is biodegradation and a lack...

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• Journal of Urban Regeneration and Renewal

  Czasopisma

  ISSN: 1752-9638

• IDRUGS

  Czasopisma

  ISSN: 1369-7056

• A Generative Approach to Hull Design for a Small Watercraft

  Publikacja

  • A. Karczewski
  • J. Kozak

  - Polish Maritime Research - Rok 2023

  In the field of ocean engineering, the task of spatial hull modelling is one of the most complicated problems in ship design. This study presents a procedure applied as a generative approach to the design problems for the hull geometry of small vessels using elements of concurrent design with multi-criteria optimisation processes. Based upon widely available commercial software, an algorithm for the mathematical formulation of...

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• Polylysine for Skin Regeneration: A Review of Recent Advances and Perspectives

  Publikacja

  • P. Zarrintaj
  • S. Ghorbani
  • M. Barani
  • N. P. Singh Chauhan
  • M. Khodadadi Yazdi
  • M. Saeb
  • J. D. Ramsey
  • M. R. Hamblin
  • M. Mozafari
  • E. Mostafavi

  - Bioengineering & Translational Medicine - Rok 2022

  There have been several attempts to find promising biomaterials for skin regeneration, among which polylysine (a homopolypeptide) has shown benefits in the regeneration and treatment of skin disorders. This class of biomaterials has shown exceptional abilities due to their macromolecular structure. Polylysine-based biomaterials can not only be used as tissue engineering scaffolds for skin regeneration, but also as drug carriers...

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• Intelligent artificial joint and regeneration problems in articular joints

  Publikacja

  • K. Wierzcholski

  - Rok 2005

  Praca przedstawia zasady działania inteligentnych sztucznych stawów biodrowych człowieka oraz problemy regeneracji chrząstek stawowych w stawach naturalnych człowieka. Postuluje się wagę podjętych badań w powyższym problemie.Zwrócono uwagę na problemy związane ze sterowaniem własności sztucznych stawów biodrowych oraz z identyfikacją impulsów przekazywanych naturalnym połączeniom stawowym człowieka.

• Comparative Analysis of Contemporary Regeneration of Waterfronts in Port Cities

  Publikacja

  • P. Lorens

  - Rok 2014

  The paper includes comparative analysis of the selected waterfront case studies in cities around Europe and North America.

• Regeneration of marine engine valves using laser surfacing

  Publikacja

  • H. Smoleńska
  • J. Łabanowski
  • W. Kończewicz

  - Welding International - Rok 2016

  This article presents an analysis of the applicability of laser surfacing of the exhaust valve face of a marine diesel engine using cobalt-based powder. After preparation by machining, the selected valves were subjected to laser surfacing using a high-power ROFIN DL020 laser. The EuTroLoy 16012 powder was used in the surfacing process. One of the valves was cut and subjected to metallographic examination and hardness measurements,...

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• ANALYSIS OF THE INCREASE OF CONSTRUCTION COSTS IN URBAN REGENERATION PROJECTS

  Publikacja

  • M. Apollo
  • E. Miszewska

  - Advances in Science and Technology Research Journal - Rok 2015

  The subject of this paper is the analysis and evaluation of the reasons for construction costs increases in urban regeneration projects. The analysis considers major refurbishments of real estates’, as well as heavy repair and modernization of the road system. For the period mentioned, the costs from works and expenditure schedules were compared with the costs of additional works, which shows the percentage cost increase in relation...

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• Public Lighting in a Context of Regeneration Processes in Polish Cities

  Publikacja

  • J. Martyniuk-Pęczek
  • N. Sokół

  - Rok 2015

  The purpose of this paper is to reflect on the role of electric lighting design in urban regeneration processes. The landscape of the modern city is the result of an accumulation of the various physical, economic, social and cultural layers over the centuries. Urban lighting may be described as one of the physical layers which due recent developments in the technology of efficient light sources overcomes a major evolution. With...

• A Review on Deactivation and Regeneration of Catalysts for Dimethyl Ether Synthesis

  Publikacja

  • J. Sobczak
  • I. Frąckiewicz
  • S. Murgrabia
  • A. Rogala

  - ENERGIES - Rok 2022

  he deactivation of catalysts and their regeneration are two very important challenges that need to be addressed for many industrial processes. The most quoted reasons for the deterioration of dimethyl ether synthesis (DME) concern the sintering and the hydrothermal leaching of copper particles, their migration to acid sites, the partial formation of copper and zinc hydroxycarbonates, the formation of carbon deposits, and surface...

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• Akrydyny jako związki aktywne przeciwnowotworowo = Acridines as antitumor drugs

  Publikacja

  • A. Dopierała
  • P. Wrosz
  • J. Mazerski

  - Postępy Higieny i Medycyny Doświadczalnej - Rok 2011

  Akrydyny należą do grupy policyklicznych związków heteroaromatycznych. Wykazują szeroki zakres aktywności biologicznej obejmujący aktywność przeciwpierwotniakową, przeciwbakteryjną,przeciwwirusową i przeciwnowotworową. Pochodne akrydyny o działaniu przeciwnowotworowym wykazują zróżnicowany mechanizm działania na poziomie molekularnym. Z uzyskanych dotychczas danych wynika, że jednym z podstawowych etapów działania jest tworzenie...

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• Poszukiwanie nowych leków immunosupresyjnych = Quest for new immunosuppressive drugs

  Publikacja

  • K. Dzierzbicka
  • G. Cholewiński
  • D. Iwaszkiewicz-Grześ
  • P. Trzonkowski

  - Wiadomości Chemiczne - Rok 2011

  Niniejsza praca przeglądowa dotyczy znanych leków immunosupresyjnych, a także nowych związków o potencjalnym zastosowaniu klinicznym. Wybrane pochodne przedstawiono z uwzględnieniem mechanizmu ich działania oraz metod otrzymywania.

• Poszukiwanie nowych leków immunosupresyjnych (Quest for new immunosuppressive drugs)

  Publikacja

  • D. Iwaszkiewicz-Grzes

  - Rok 2011

  Transplantology is getting more and more important in medicine. Development of surgical techniques and immunosuppressive treatment enabled to establish successful transplantations with various organs and tissues. However, allografts are recognized as foreign tissues and stimulate rejection, i.e. a strong immunological response which, if not stopped, results in complete destruction of the transplanted tissue. In order to prevent...

• Inhibitors of glucosamine-6-phosphate synthase as potential antifungal drugs.

  Publikacja

  • S. Milewski
  • R. Andruszkiewicz
  • A. Janiak
  • I. Gabriel
  • J. Olchowy
  • R. Wakieć
  • E. Borowski

  - Rok 2004

  Przedstawiono stan obecny i perspektywy zastosowania inhibitorów enzymu syntazy GlcN-6-P jako leków skutecznych w leczeniu grzybic układowych. Używając metod modelowania molekularnego zaprojektowano struktury inhibitorów enzymu należących do dwóch grup strukturalnych: analogów glutaminy oraz analogów stanu przejściowego reakcji katalizowanej przez enzym. Opracowano metody syntezy pochodnych zoptymalizowanych inhibitorów, wykazujących...

• Issues in the development of new combinations of blood pressure lowering drugs

  Publikacja

  • J. Chalmers
  • S. Harrap
  • K. Narkiewicz
  • N. Poulter
  • J. Redon
  • A. Zanchetti
  • G. Mancia

  - JOURNAL OF HYPERTENSION - Rok 2010

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• The Effect of Antihypertensive Drugs on NADH in Newly Diagnosed Primary Hypertension

  Publikacja

  • R. Pawlak-Chomicka
  • T. Krauze
  • P. Uruski
  • J. Piskorski
  • A. Wykretowicz
  • A. Tykarski
  • P. Guzik

  - Cardiology Research and Practice - Rok 2022

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• Marine Drugs

  Czasopisma

  ISSN: 1660-3397

• Monitoring Regenerative Heat Exchanger in Steam Power Plant by Making Use of the Recurrent Neural Network

  Publikacja

  • T. Niksa-Rynkiewicz
  • N. Szewczuk-Krypa
  • A. Witkowska
  • K. Cpałka
  • M. Zalasiński
  • A. Cader

  - Journal of Artificial Intelligence and Soft Computing Research - Rok 2021

  Artificial Intelligence algorithms are being increasingly used in industrial applications. Their important function is to support operation of diagnostic systems. This paper pesents a new approach to the monitoring of a regenerative heat exchanger in a steam power plant, which is based on a specific use of the Recurrent Neural Network (RNN). The proposed approach was tested using real data. This approach can be easily adapted to...

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• Bacterial cellulose in the field of wound healing and regenerative medicine of skin: recent trends and future prospectives

  Publikacja

  • J. Kucińska-Lipka
  • I. Carayon
  • H. Janik

  - POLYMER BULLETIN - Rok 2015

  In this overview, we focused on the bacterial cellulose (BC) applications, described in recently published scientific papers, in the field of skin regenerative medicine and wound care industry. Bacterial cellulose was proven to be biocompatible with living tissues. Moreover, its mechanical properties and porous structure are considered to be suitable for biomedical applications. It is due to the fact that porous structure of bacterial...

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• The evolution of education spaces - from plan as generator to regenerative architecture, virtual rooms and green campuses

  Publikacja

  • J. Szczepański
  • L. Nyka

  - Global Journal of Engineering Education - Rok 2023

  The study programmes are often considered the main formative factors in the process of educating future architects. Another highly influential component is the architectural characteristics of learning spaces, and consequently the impact of the physical built environment on the quality of education has been widely discussed. However, not often do we realise that the characteristics of education spaces correlate with the organisational...

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• Genome-wide DNA methylation profiling of the regenerative MRL/MpJ mouse and two normal strains

  Publikacja

  • B. Górnikiewicz
  • A. Ronowicz
  • P. Madanecki
  • P. Sachadyn

  - EPIGENOMICS-UK - Rok 2017

  Aims We aimed to identify the pivotal differences in the DNA methylation profiles between the regeneration capable MRL/MpJ mouse and reference mouse strains. Materials and Methods Global DNA methylation profiling was performed in ear pinnae, bone marrow, spleen, liver, heart from uninjured adult females of the MRL/MpJ and C57BL/6J and BALB/c. Results and conclusion A number of differentially methylated regions distinguishing between...

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• Applying Generative Modelling Tools to Explore Architectural Forms

  Publikacja

  • M. Helenowska-Peschke

  - The Journal of Polish Society for Geometry and Engineering Graphics - Rok 2012

  The digital generative methods open up new areas for exploration of formal and tectonic features, accentuate form’s ability to emerge and perform. They allow for automatic generation of variations of solutions, and digital production of “difficult” components of architectural forms using CNC technology.The paper deals with contemporary architectural explorations of complex , curvilinear surfaces in the context of generative...

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• Interactive generative system supporting participatory house design

  Publikacja

  • K. Kwieciński
  • J. Słyk

  - AUTOMATION IN CONSTRUCTION - Rok 2023

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• DRUGS IN R&D

  Czasopisma

  ISSN: 1174-5886 , eISSN: 1179-6901

• Drugs and Alcohol Today

  Czasopisma

  ISSN: 1745-9265 , eISSN: 2042-8359

• Clinical Cancer Drugs

  Czasopisma

  ISSN: 2212-697X

• Drugs and Therapy Perspectives

  Czasopisma

  ISSN: 1172-0360

• INVESTIGATIONAL NEW DRUGS

  Czasopisma

  ISSN: 0167-6997 , eISSN: 1573-0646

• Journal of Psychoactive Drugs

  Czasopisma

  ISSN: 0279-1072 , eISSN: 2159-9777

• Journal of Drugs in Dermatology

  Czasopisma

  ISSN: 1545-9616