Wyszukiwarka
Filtry
wszystkich: 22432
-
Katalog
- Publikacje 1911 wyników po odfiltrowaniu
- Czasopisma 49 wyników po odfiltrowaniu
- Konferencje 12 wyników po odfiltrowaniu
- Osoby 67 wyników po odfiltrowaniu
- Wynalazki 1 wyników po odfiltrowaniu
- Projekty 1 wyników po odfiltrowaniu
- Kursy Online 6 wyników po odfiltrowaniu
- Wydarzenia 4 wyników po odfiltrowaniu
- Dane Badawcze 20381 wyników po odfiltrowaniu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: PATENTS
-
Evaluation of Body Surface Area Formulae Based on 3D Body Scans
PublikacjaHuman body surface area (BSA) is an established parameter for the calculation of chemotherapy drugs dosage, treatment of chronic hepatitis B, treatment of burns or for establishing a dosing regimen for antimicrobials. Although being a critical parameter, usage of modern 3D scanners, which would measure the exact BSA value, is often impossible in time-sensitive operations or for patients unable to withstand the scanning process....
-
A multisensor detector of a sleep apnea for using at home
PublikacjaDiagnosis of obstructive sleep apnea usually involves polysomnographic analysis, which unfortunately requires overnight stay in a specialized clinic and is very uncomfortable for a patient. This paper describes the method and apparatus for recording a set of signals to detect sleep apnea. The device records the following signals simultaneously: three-channel ECG, respiratory functions, signals from the accelerometer, and snoring...
-
Jacek Marszal dr hab. inż.
OsobyDr hab. inż. Jacek Marszal, prof. nadzw. PG ukończył w roku 1977 studia magisterskie na Wydziale Elektroniki Politechniki Gdańskiej w zakresie Aparatury Elektronicznej. W 1989 r. uzyskał stopień doktora nauk technicznych w dyscyplinie Telekomunikacja, a w roku 2014 stopień doktora habilitowanego w tej samej dyscyplinie. Jego specjalnością naukową jest hydroakustyka. Bezpośrednio po ukończeniu studiów rozpoczął pracę na Wydziale...
-
Intelligent Virtual Agents
Konferencje -
Michał Tomasz Kucewicz dr
OsobyMichal Kucewicz was born in 1986 in Gdansk. In 2005 he completed International Baccalaureate programme in Topolowka (III High School in Gdańsk). Thanks to the G. D. Fahrenheit scholarship, he moved to the United Kingdom to study neuroscience. He received his Bachelor’s and Master’s degree from the Cambridge University, and his doctoral degree from the University of Bristol specializing in electrophysiology of memory and cognitive...
-
Krzysztof Nyka dr hab. inż.
OsobyKrzysztof Nyka, absolwent Wydziału Elektroniki Telekomunikacji i Informatyki Politechniki Gdańskiej (WETI PG), gdzie uzyskał tytuł magistra inżyniera (1986, telekomunikacja) stopień doktora nauk technicznych (2002, elektronika) i doktora habilitowanego (2020 automatyka, elektronika i elektrotechnika). Obecnie jest zatrudniony na stanowisku profesora uczelni w Katedrze Inżynierii Mikrofalowej i Antenowej WETI PG. Zainteresowania...
-
Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublikacjaBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
-
Validation of EORTC, CUETO and EAU risk stratification in prediction of recurrence, progression and death of patients with initially non-muscle invasive bladder cancer (NMIBC): a cohort analysis with systematic review.
Publikacja -
DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL
Publikacja -
Insulin-like growth factor type 2 is better than insulin-like growth factor type 1 a survival marker in patients after acute decompensation of heart failure
PublikacjaIntroduction:A decreased IGF-1 has been found in heart failure (HF). There are no reports assessing IGF-2 in HF, although in vitro study has shown, that IGF-2 stimulates cardiomyocyte proliferation more than IGF-1. The study aim was to compare the IGF-1 and IGF-2 concentration depending on HF exacerbation and annual survival.Material and methods:Among 75 patients hospitalized...
-
The use of Yttrium-90 Ibritumomab Tiuxetan ( 90 Y-IT) as a consolidation therapy in high-risk patients with diffuse large B-cell lymphoma ineligible for autologous stem-cell transplantation
Publikacja -
Ibrutinib versus temsirolimus: 3-year follow-up of patients with previously treated mantle cell lymphoma from the phase 3, international, randomized, open-label RAY study
Publikacja -
Idelalisib or placebo in combination with bendamustine and rituximab in patients with relapsed or refractory chronic lymphocytic leukaemia: interim results from a phase 3, randomised, double-blind, placebo-controlled trial
Publikacja -
Współpraca patentowa nauki i biznesu na przykładzie województwa podkarpackiego – analiza sieci / Network analysis of patent cooperation between science and business - the case of Subcarpathian region
Publikacja -
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
Czasopisma -
Validation of high-resolution 3D patient QA for proton PBS and IMPT using laser CT of improved polymer gel dosimeters
Publikacja -
Single-agent MOR208 salvage and maintenance therapy in a patient with refractory/relapsing diffuse large B-cell lymphoma: a case report
Publikacja -
Pd-catalysed general access to 7-membered N/O-heterocyclic compounds as potential agents against inflammation
Publikacja -
Vascular endothelial growth factor (VEGF)-C - a potent risk factor in children diagnosed with stadium 4 neuroblastoma.
Publikacja -
Vascular endothelial growth factor C—a potent risk factor in childhood acute lymphoblastic leukaemia: an immunocytochemical approach
Publikacja -
Highly Potent Antidiuretic Antagonists: Conformational Studies of Vasopressin Analogues Modified with 1-Naphthylalanine Enantiomers at Position 2
Publikacja -
The Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor
Publikacja -
Absence of 6-Hydroxydopamine in the Rat Brain After Treatment with Stimulants and Other Dopaminergic Agents: A Mass Fragmentographic Study
Publikacja -
N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H3 receptor and cancer resistance proteins
Publikacja -
Silicon polypodands: powerful metal cation complexing agents and solid–liquid phase-transfer catalysts of new generation
Publikacja -
Potent antitumor 4-methyl-1-nitroacridine C-1748 induces apoptosis only in part of colon cells
PublikacjaCelem przedstawionej pracy było zbadanie zdolności pochodnej 1-nitroakrydyny C-1748 do indukcji apoptozy komórek raka jelita grubego HCT8 i HT29 pochodzenia ludzkiego. Śmierć komórek była badana przez określony czas inkubacji komórek ze związkiem w stężeniach odpowiadających wartościom EC90 lub ich wielokrotnościom przez czas od 3 do 72 godzin. Uzyskane wyniki wskazują, że C-1748 indukuje apoptozę zależną od czasu tylko w części...
-
Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305
PublikacjaWykazaliśmy, że pochodna triazoloakrydonu C-1305 w stężeniach biologicznie istotnych indukuje blok cyklu komórkowego w fazie G2/M i apoptozę w komórkach białaczek ludzkich MOLT4 i HL60. Zjawisko apoptozy zostało określone na podstawie charakterystycznych zmian morfologicznych jak i biochemicznych tj. fragmentacji DNA, aktywacji kaspazy 3, cięcia PARP, spadku potencjału mitochondrialnego i ATP oraz eksternalizacji fosfatydyloseryny.
-
Potent antitumor 4-methyl-1-nitroacridine C-1748 induces apoptosis only in part of colon cells
PublikacjaZbadaliśmy zdolność pochodnej 4-metylo-1-nitroakrydyny C-1748 do indukcji apoptozy w ludzkich komórkach nowotworów jelita grubego HCT-8 i HT29 w stężeniach biologicznie istotnych. Zjawisko apoptozy określiliśmy na podstawie zmian morfologicznych jak i biochemicznych tj. fragmentacji DNA, aktywacji kaspazy-3, spadku potencjału mitochondrialnego, eksternalizacji fosfatydyloseryny i pojawiania się frakcji sub-G1. Wykazaliśmy, że pochodna...
-
DNA methylation in cancer development, diagnosis and therapy-multiple opportunities for genotoxic agents to act as methylome disruptors or remediators
PublikacjaThe role of DNA methylation and recently discovered hydroxymethylation in the function of the human epigenome is currently one of the hottest topics in the life sciences. Progress in this field of research has been further accelerated by the discovery that alterations in the methylome are not only associated with key functions of cells and organisms, such as development, differentiation and gene expression, but may underlie a number...
-
Synthesis of new antrapyridazone derivatives - a novel group of anticancer agents active on a multidrugresistant(MDR) tumor cell lines
PublikacjaNovel antrapyridazone derivatives were synthesized and biologically evaluated in order tobroaden the data on structure-activity relationship of this class of cytostatics. Recent literaturedata prove that acetamides react better with aryl chlorides. A new approach based onintroduction of other amides form into aromatic ring in Ullmann was tested. This new methodcould give better yields and make purification step more convenient.
-
The hydration of the protein stabilizing agents: trimethylamine-N-oxide, glycine and its N-methylderivatives - the volumetric and compressibility studies
PublikacjaThe densities at T = (288.15, 293.15, 298.15, 303.15, and 308.15) K and sound velocities at T = 298.15 K have been measured for aqueous solutions of trimethylamine-N-oxide, glycine, N-methylglycine (sarcosine), N,N-dimethylglycine, N,N,N-trimethylglycine (betaine). From these data the apparent molar volumes, VΦ, the apparent molar isentropic compressions, KS,Φ, and the solvation numbers of solutes have been determined. The concentration...
-
Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
PublikacjaElectrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...
-
Self-Organising map neural network in the analysis of electromyography data of muscles acting at temporomandibular joint.
PublikacjaThe temporomandibular joint (TMJ) is the joint that via muscle action and jaw motion allows for necessary physiological performances such as mastication. Whereas mandible translates and rotates [1]. Estimation of activity of muscles acting at the TMJ provides a knowledge of activation pattern solely of a specific patient that an electromyography (EMG) examination was carried out [2]. In this work, a Self-Organising Maps (SOMs)...
-
Interaction with medical data using QR-codes
PublikacjaBar-codes and QR-codes (Quick Response ) are often used in healthcare. In this paper an application of QR-codes to exchange of laboratory results is presented. The secure data exchange is proposed between a laboratory and a patient and between a patient and Electronic Health Records. Advanced Encryption Standard was used to provide security of data encapsulated within a QR-code. The experimental setup, named labSeq is described....
-
Novel Nystatin A1 derivatives exhibiting low host cell toxicity and antifungal activity in an in vitro model of oral candidosis
PublikacjaOpportunistic oral infections caused by Candida albicans are frequent problems in immunocompromised patients. Management of such infections is limited due to the low number of antifungal drugs available, their relatively high toxicity and the emergence of antifungal resistance. Given these issues, our investigations have focused on novel derivatives of the antifungal antibiotic Nystatin A1, generated by modifications at the amino...
-
Czynniki kształtujące środowisko pacjenta w szpitalu
PublikacjaSzpital jest miejscem szczególnym – z założenia przebywają w nim osoby, znajdujące się w sytuacji niekomfortowej. Możliwości adaptacji w nowym środowisku u osób chorych, osłabionych lub osób z niepełnosprawnościami są znacząco obniżone, a przecież szpital należy do budynków o najbardziej skomplikowanej strukturze funkcjonalno-przestrzennej. Stan emocjonalny pacjenta w środowisku szpitalnym jest uzależniony od relacji z lekarzami...
-
Association between plasma proteome profiles analysed by mass spectrometry, a lymphocyte-based DNA-break repair assay and radiotherapy-induced acute mucosal reaction in head and neck cancer patients
Publikacja -
Proprotein Convertase Subtilisin/Kexin Type 9, Angiopoietin-Like Protein 8, Sortilin, and Cholesteryl Ester Transfer Protein—Friends of Foes for Psoriatic Patients at the Risk of Developing Cardiometabolic Syndrome?
Publikacja -
Cladribine Combined with Low-Dose Cytarabine as Frontline Treatment for Unfit Elderly Acute Myeloid Leukemia Patients: Results from a Prospective Multicenter Study of Polish Adult Leukemia Group (PALG)
Publikacja -
Influence of Early versus Late supplemental ParenteraL Nutrition on long-term quality of life in ICU patients after gastrointestinal oncological surgery (hELPLiNe): study protocol for a randomized controlled trial
Publikacja -
Elevated Levels of Renalase, the β-NAD(P)H Isomerase, Can Be Used as Risk Factors of Major Adverse Cardiovascular Events and All-Cause Death in Patients with Chronic Kidney Disease
Publikacja -
Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries
Publikacja -
Rituximab biosimilar and reference rituximab in patients with previously untreated advanced follicular lymphoma (ASSIST-FL): primary results from a confirmatory phase 3, double-blind, randomised, controlled study
Publikacja -
Anterior subcutaneous transposition and simple decompression of the ulnar nerve at the elbow – the postoperative improvement in DASH score, VAS score and sonographic findings
PublikacjaIntroduction. Although a lot of studies have described long- term outcomes after surgical treatment of cubital tunnel syndrome, and the usefulness of sonography in diagnosing of this disorder, few studies have evaluated patients self-reporting outcomes or sonographic findings after surgery. Aim. We assessed patients self-reporting instruments and sonographic findings in patients with the cubital tunnel syndrome before and after...
-
Jan Cudzik dr inż. arch.
OsobyJan Cudzik (dr inż. arch.) jest adiunktem w Katedrze Architektury Miejskiej i Przestrzeni Nadwodnych na Wydziale Architektury Politechniki Gdańskiej oraz kierownikiem Laboratorium Cyfrowych Technologii i Materiałów Przyszłości. Prowadzi badania nad architekturą kinetyczną, technikami cyfrowymi w projektowaniu architektonicznym, fabrykacją cyfrową oraz formami sztucznej inteligencji w architekturze i sztuce. Jego badania nad automatyzacją...
-
A New Approach to Assess Quality of Motion in Functional Task of Upper Limb in Duchenne Muscular Dystrophy
Publikacja(1) Background: This study presents a new method for the motion quantitative analysis of Duchenne muscular dystrophy patients (DMD) performing functional tasks in clinical conditions. (2) Methods: An experimental study was designed to define how different levels of external mass (light and heavy) influence the performance of the upper limbs of a tested DMD and reference subject (RS) during horizontal movements (level of the waist)...
-
Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer
PublikacjaThe molecular mechanisms of telomerase reverse transcriptase (TERT) upregulation in breast cancer (BC) are complex. We compared genetic variability within TERT and telomere length with the clinical data of patients with BC. Additionally, we assessed the expression of the TERT, MYC, TP53 and SP1 genes in BC patients and in BC organoids (3D cell cultures obtained from breast cancer tissues). We observed the same correlation in the...
-
New aspects in assessment of changes in width of subarachnoid space with near-infrared transillumination/backscattering sounding, part 2: clinical verification in the patient
PublikacjaW pracy przedstawiono porównanie wyników symulacji propagacji promieniowania z zakresu bliskiej podczerwieni z danymi uzyskanymi na drodze pomiarów wykonanych w warunkach klinicznych. Różnice między nimi nie przekraczały 4 dB, co potwierdziło słuszność przyjętych założeń w procesie symulacji. W pomiarach wykorzystano unikatowy zetstaw nadajników i odbiorników promieniowania podczerwonego, pozwalającego prowadzenie pomiarów transmisji...
-
Novel molecules containing structural features of NSAIDs and 1,2,3-triazole ring: Design, synthesis and evaluation as potential cytotoxic agents
PublikacjaFor the first time the template containing structural features of more than one NSAIDs and the 1,2,3-triazole ring was explored for the identification of potential cytotoxic agents. These new and complex molecules were predicted to be effective inhibitors of PDE4B by molecular modelling studies in silico. The multi-step synthesis of these compounds were carried out starting from the well-known drug nimesulide and involved the use...
-
Novel molecules containing structural features of NSAIDs and 1,2,3-triazole ring: Design, synthesis and evaluation as potential cytotoxic agents
Publikacja