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„Gdański eksperyment” studentów PG poleci rakietą z Europejską Agencją Kosmiczną
PublikacjaPięcioosobowy zespół studentów Politechniki Gdańskiej, który przyjął nazwę HEDGEHOG (High quality Experiment Dedicated to microGravity Exploration, Heat flow and Oscillation measurement from Gdansk), zakwalifikował się do programu REXUS/BEXUS Student Experiment Programme koordynowanego przez Europejską Agencję Kosmiczną (ESA). W lutym 2018 roku studenci polecą do kosmodromu Esrange nieopodal Kiruny w północnej Szwecji, by poszerzyć...
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Resistance of Escherichia coli and Enterococcus spp. to selected antimicrobial agents present in municipal
PublikacjaIn this study, the susceptibility to erythromycin (E) and to trimethoprim/sulfamethoxazole (SXT) among isolates of Enterococcus spp. and Escherichia coli was tested, respectively. Both fecal indicators were detected and isolated from raw(RW) and treated wastewater (TW) as well as from samples of activated sludge (AS) collected in a local wastewater treatment plant (WWTP). Biodiversity of bacterial community in AS was also monitored...
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Natural Deep Eutectic Solvents as Agents for Improving Solubility, Stability and Delivery of Curcumin
PublikacjaPurpose Study on curcumin dissolved in natural deep eutectic solvents (NADES) was aimed at exploiting their beneficial properties as drug carriers. Methods The concentration of dissolved curcumin in NADES was measured. Simulated gastrointestinal fluids were used to determine the concentration of curcumin and quantum chemistry computations were performed for clarifying the origin of curcumin solubility enhancement in NADES. Results NADES...
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Selected anionic and cationic surface active agents: case study on the Kłodnica sediments
PublikacjaSurface active agents (surfactants) are a group of chemical compounds, which are used as ingredients of detergents, cleaning products, cosmetics and functional products. After use, wastes containing surfactants or their degradation products are discharged to wastewater treatment plants or directly into surface waters. Due to their specific properties of SAAs, compounds are able to migrate between different environmental compartments...
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Analysing Ways to Achieve a New Urban Agenda-Based Sustainable Metropolitan Transport
PublikacjaThe New Urban Agenda (NUA) sets a new vision of sustainable urban development to help cities deal with the challenges of changing demography. While numerous articles have addressed how the NUA can be implemented at different levels and in different areas, this article points out the potential limitations in incorporating the NUA into metropolitan transport policies. The relevance of the limitations can be seen in three main fields:...
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SYNTHESIS OF PHOSPHORUS TACRINE ANALOGUES AS A NEW POTENTIAL ANTI-ALZHEIMER’S DISEASE AGENTS
PublikacjaA series of novel phosphorus tacrine derivatives was obtained in three steps, including synthesis of 9-chlorotacrine, connection of 9-chlorotacrine with hexamethylenediamine, 1,8-diaminooctane and 1,12-diaminododecane linkers and reaction of obtained tacrine diamine analogues with corresponding acid ester to give nine tacrine organophosphorus compounds. All of the obtained final structures were characterized by 1H NMR, 13C NMR,...
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Learning and memory processes in autonomous agents using an intelligent system of decision-making
PublikacjaThis paper analyzes functions and structures of the memory that is an indispensable part of an Intelligent System of Decision-making (ISD), developed as a universal engine for autonomous robotics. A simplified way of processing and coding information in human cognitive processes is modelled and adopted for the use in autonomous systems. Based on such a knowledge structure, an artificial model of reality representation and a model...
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Learning and memory processes in autonomous agents using an intelligent system of decision-making
PublikacjaThis paper analyzes functions and structures of the memory that is an indispensable part of an Intelligent System of Decision-making (ISD), developed as a universal engine for autonomous robotics. A simplified way of processing and coding information in human cognitive processes is modelled and adopted for the use in autonomous systems. Based on such a knowledge structure, an artificial model of reality representation and a model...
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Overcome the tumor immunotherapy resistance by combination of the HDAC6 inhibitors with antitumor Immunomodulatory agents.
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Rational design, synthesis and biological evaluation of thiadiazinoacridines: a new class of antitumor agents.
PublikacjaZsyntetyzowano serię związków o potencjalnej zdolności do wiązania się z DNA z grupy tiadiazinoakrydyn poprzez cyklizację odpowiednich pochodnych 9-imino-4-nitro-9,10-dihydroakrydyny. Zbadano ich zdolność do wiązania się z DNA oraz cytotoksyczność względem kilku linii komórek nowotworwych. Badania aktywności przeciwnowotworowej wobec białaczki P388 wskazały na zgodność tych wyników z wynikami cytotoksyczności in vitro. Wykazano,...
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In Search of Panacea—Review of Recent Studies Concerning Nature-Derived Anticancer Agents
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Innovation in sustainable development: an investigation of the EU context using 2030 agenda indicators
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Exploring an Ontological Approach for User Requirements Elicitation in the Design of Online Virtual Agents
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UK travel agents’ evaluation of eLearning courses offered by destinations: an exploratory study.
PublikacjaThis study aims to develop an understanding of the use of e-learning courses created for travel agents by Destination Management Organizations (DMOs). It explores agents’ perceptions of such courses. The research examines the views of 304 UK-based travel agents using online survey and investigates whether age, sex, type of agency, work experience, and educational level have influence on e-learning uptake. The satisfaction of travel...
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Natural and synthetic acridines/acridones as antitumor agents: their biological activities and methods of synthesis.
PublikacjaPraca stanowi przegląd opisanych w literaturze chemicznej modyfikacji struktur naturalnych i syntetycznych pochodnych akrydyny i akrydonu. Artykuł obejmuje swym zakresem metody syntezy, a także wpływ budowy cząsteczek tych związków na ich aktywność przeciwnowotworową oraz mechanizm działania.
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Isothiocyanates as effective agents against enterohemorrhagic Escherichia coli: insight to the mode of action
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Deep Eutectic Solvents as Agents for Improving the Solubility of Edaravone: Experimental and Theoretical Considerations
PublikacjaIn this study, both practical and theoretical aspects of the solubility of edaravone (EDA) in Deep Eutectic Solvents (DESs) were considered. The solubility of edaravone in some media, including water, can be limited, which creates the need for new efficient and environmentally safe solvents. The solubility of EDA was measured spectrophotometrically and the complex intermolecular interactions within the systems were studied with...
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Deep Eutectic Solvents as Agents for Improving the Solubility of Edaravone: Experimental and Theoretical Considerations
PublikacjaIn this study, both practical and theoretical aspects of the solubility of edaravone (EDA) in Deep Eutectic Solvents (DESs) were considered. The solubility of edaravone in some media, including water, can be limited, which creates the need for new efficient and environmentally safe solvents. The solubility of EDA was measured spectrophotometrically and the complex intermolecular interactions within the systems were studied with...
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Entangled rendezvous: a possible application of Bell non-locality for mobile agents on networks
PublikacjaRendezvous is an old problem of assuring that two or more parties, initially separated, not knowing the position of each other, and not allowed to communicate, are striving to meet without pre-agreement on the meeting point. This problem has been extensively studied in classical computer science and has vivid importance to modern and future applications. Quantum non-locality, like Bell inequality violation, has shown that in many...
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Exploring ontological approach for user requirements elicitation in design of online virtual agents
PublikacjaEffective user requirements elicitation is a key factor for the success of software development projects. There are many qualitative and quantitative research studies that promulgate particular methods and show the application of user requirements elicitation in particular domains. However, few try to eliminate the burden of ambiguity in gathered data, naturally occurring in different groups of stakeholders. This paper deals with...
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Ruthenium(II) and Iridium(III) Complexes as Tested Materials for New Anticancer Agents
PublikacjaThe oncological use of cisplatin is hindered by its severe side eects and a very important resistance problem. To overcome these problems, scientists have attempted to design new generation transition-metal anticancer complexes. In this study, we present new complexes, ruthenium(II) [(6-p-cymene)RuCl(py2CO)]PF6 (1), iridium(III) [(5-Cp)IrCl(py2CO)]PF6 (2), and NH4[IrCl4(py2CO)]H2O (3), based on di-2-pyridylketone (py2CO). The prepared...
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Wojciech Chrzanowski dr hab. inż.
OsobyWojciech Chrzanowski, urodzony w 1952 r. w Toruniu, ukończył w 1975 r. studia magisterskie na kierunku Technologia Chemiczna, w specjalności Technologia Nieorganiczna (specjalizacja: ochrona przed korozją), na Wydziale Chemicznym PG, uzyskując dyplom z wyróżnieniem. W tym samym roku został zatrudniony w Zakładzie Technik Analitycznych ówczesnego Instytutu Inżynierii Chemicznej i Technik Pomiarowych, początkowo na stanowisku technicznym,...
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Detection of immunological agent by optical fiber sensor: preliminary study
PublikacjaThe objective of this study is the application of optical methods for detection of immunological agent concentration. As the agent we used the Cyclaid, produced by Apotex Inc. In this article we investigated different Cyclaid concentrations in water. We used a Fabry-Pérot interferometer working in a reflective mode, the measurements were performed with source with central wavelength λ = 1550 nm. The preliminary investigation have...
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Machine Learning in Multi-Agent Systems using Associative Arrays
PublikacjaIn this paper, a new machine learning algorithm for multi-agent systems is introduced. The algorithm is based on associative arrays, thus it becomes less complex and more efficient substitute of artificial neural networks and Bayesian networks, which is confirmed by performance measurements. Implementation of machine learning algorithm in multi-agent system for aided design of selected control systems allowed to improve the performance...
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Multi-Agent Signal Filtering for Electrical Energy Demand Management
PublikacjaConsumers participating in electrical energy Demand Response (DR) programs may be exposed to energy-use related decisions at instants of time which are generally hard to predict. This is especially cumbersome to residential consumers who are less capable of investing in special equipment, or devoting significant time to analyze information and take decisions. To ease residential consumer participation, a multi-agent system proposed...
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Mesoporous Silica Nanospheres Functionalized by Tio2 as a Photoactive Antibacterial Agent
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History-based dynamic weight voting for multi-agent systems
PublikacjaTaking decision in multi-agent systems may involve voting. Two basic voting protocols are surveyed in the paper. Then, a new history-based dynamic weight voting is proposed. This voting protocol allows for identification of the agents which contribute to the correct system decision. The proposed solution is contrasted with majority voting and with weighted average voting, to show its advantages
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A Human Behaviour Model Agent for Testing of Voluntary Computing Systems
PublikacjaPaper presents a design and performance of a voluntary-based distributed computing system testing agent, implementing a human behaviour model. The agent, nicknamed iRobot, was designed and implemented to enable controlled, large scale testing of core algorithms of Comcute - a new voluntary distributed computing platform complementary to BOINC. The main agent design goals were: emulation of human behaviour when browsing web pages,...
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Agent-Based Population Learning Algorithm for RBF Network Tuning
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Implementation and performance evaluation of the agent-based algorithm for ANN training
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Agent-Based Approach to RBF Network Training with Floating Centroids
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An Experimental Study of Scenarios for the Agent-Based RBF Network Design
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Conjugate of Enkephalin and Temporin Peptides as a Novel Therapeutic Agent for Sepsis
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Validation of an Agent and Ontology-based Information Technology Assessment System
PublikacjaThe aim of this paper is to present a new method of the validation of an Agent and Ontology-based Information Technology Assessment System. In the introduction part of the paper, the characteristics of the proposed multi-agent system are presented. Next, some important details regarding the ontology functionality of this system are described and an approach to its verification process is proposed. The approach employs semantic...
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Supporting Software Project Management Processes Using the Agent System
PublikacjaThe natural development of information technology area stimulates intense growth of various technologies which support basic organization processes. The range of technologies implies appropriate management thereof, as well as accurate correspondence with conducted activities. Abandonment of activities within individual branches in favour of project approach to performed assignments (especially those connected with software development)...
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An application of multi-agent system for ship’s power systems design
PublikacjaDesign process of transport ship power system consists of structure (topology) and component elements selection. Compliance with the requirements for static components does not guarantee optimal dynamic characteristics of entire power system. Design steps are difficult to formalize and as a consequence to this reason expert and multi-agent systems are used for solving selected design issues. In the paper distributed multi-agent...
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Obliczenia rozpływu powietrza chłodzącego w turbinie gazowej
PublikacjaOptymalizacja spełnia ważną funkcję, pozwala nam zminimalizować straty poniesione poprzez zastosowanie chłodzenia. Głównym celem artykułu była optymalizacja rozpływu powietrza chłodzą-cego tak aby zminimalizować straty mocy spowodowane podziałem strumienia powietrza, takie dobranie upustów w sprężarce aby moc w turbinie była jak największa, a moc sprężarki jak najmniejsza. W artykule zawarto model obliczeń, przedstawiono podstawowy...
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Krzysztof Czerwionka dr hab. inż.
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Poszukiwanie optymalnego ustawienia elementów tłumiących drgania dla ciała poddanego dwóm stanom obciążenia, przy ograniczeniu pola mocowania elementów.
PublikacjaW pracy podjęto próbę połączenia procedur badania dynamiki układów wielomasowych z procedurami optymalizacji numerycznej metodą sympleksów. Poszukiwano optymalnego ustawienia elementów tłumiących drgania występujące w układzie. Poddano je testowi dla układu poddanego dwóm stanom obciążenia. Zaproponowano modyfikację sposobu optymalizacji. Otrzymano przykładowe rozwiązanie dla wybranego, fikcyjnego układu o fikcyjnych wartościach...
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Bee Products and Essential Oils as Alternative Agents for Treatment of Infections Caused by S. aureus
PublikacjaBacteria of the genus Staphylococcus are important human and veterinary pathogens. A crucial characteristic for this group of bacteria is that they can easily acquire mechanisms of antibiotic resistance for a plethora of antibiotics currently in use for human and animal therapies. Therefore, there is a great need to find novel, non-antibiotic chemotherapeutics with marked antistaphylococcal activity. Promising but still underestimated...
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Selected anionic and cationic surface active agents determined in river sediments – the Klodnica catchment
PublikacjaSurface active agents (SAAs) are specific compounds that contain hydrophilic/ hydrophobic group in their molecules named as amphiphilic structures. According to charge on the hydrophilic part of surfactants they can be classified into three main groups: anionic, cationic and non-ionic compounds. Due to the amphiphilic structure of SAAs they have specific properties (e.g. ability to adsorption at different surfaces, reduction of...
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New Class of Antimicrobial Agents: SBA-15 Silica Containing Anchored Copper Ions
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Current state of a dual behaviour of antimicrobial peptides-Therapeutic agents and promising delivery vectors
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The use of eLearning strategies among travel agents in the United Kingdom, India and New Zealand
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Fermented juices as reducing and capping agents for the biosynthesis of size-defined spherical gold nanoparticles
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High resolution model for assessment of contamination by chemical warfare agents dumped in the Baltic Sea
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Structural Characterization and in Vivo Evaluation of β-Hairpin Peptidomimetics as Specific CXCR4 Imaging Agents
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Scalable Maintenance of Address Mapping and Autodetecion in Environments Where Agents are Uncapable of Self-Registration
PublikacjaWhen working with multi-agent systems it is often desirable to manage the agent set. The existing methods of central monitoring stems from two different fields of application. The first has its roots in in computer network monitoring, the other in mutli-agent simulation environments. Both approaches are not general enough to cater for loosely controlled environments, where the total agent population is not known and often fluctuating,...
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublikacjaA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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Effect of glycols used as glycolysis agents on chemical structure and thermal stability of produced glycolysates
PublikacjaZaprezentowano warunki glikolizy poliuretanowych odpadów piankowych, przy użyciu różnych glikoli oraz wyniki badań budowy chemicznej glikolizatów oraz ich właściwości termicznych.