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Search results for: biological%20activity
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Antimicrobial Activity of Honey
PublicationHoney has had a valued place in traditional medicine for centuries. It was used to overcome liver, cardiovascular and gastrointestinal problems and for treatment of some types of infectious disease. Particularly, good results were achieved in the case of application of this product for therapy of infected, difficult to heal wounds. The high health-promoting properties of honey have been recently confirmed in many research investigations....
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ECOLOGICAL MODELLING
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Ecological Informatics
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Mirosław Andrusiewicz prof. dr hab. n. med. i n. o zdr.
PeopleDiplomas, degrees conferred in specific areas ̶ Post-doctoral degree in medical sciences (doctor habilitated) (discipline: medical biology) December 4, 2017; Title of academic achievement: "Analysis of selected genes involved in the control of pathological changes in cells derived from internal female reproductive organs"; Poznan University of Medical Sciences, Faculty of Medicine II; re-viewers: Prof. Katarzyna Ziemnicka,...
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A Comprehensive Review on the Medicinal Importance; Biological and Therapeutic Efficacy of Lagenaria siceraria (Mol.) (Bottle Gourd) Standley Fruit
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In silico studies and β-cyclodextrin mediated neutral synthesis of 4-oxo-4,5,6,7-tetrahydroindoles of potential biological interest
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Penetrating Biological Tissue Using Light-Emitting Diodes with a Highly Efficient Near-Infrared ScBO3:Cr3+ Phosphor
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Design, synthesis and biological evaluation of betulin-3-yl 2-amino-2-deoxy-β-d-glycopyranosides
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Methods and means of measuring control and diagnostics of biological tissues in vivo based on measurements of color coordinates and multispectral image
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Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples
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Comparison of two model concepts for simulation of nitrogen removal at a full-scale biological nutrient removal pilot plant
PublicationCelem badań było porównanie zdolności predykcyjnych dwóch mechanistycznych modeli procesu osadu czynnego (ASM1 i ASM3). W tym celu wykorzystano bazę danych empirycznych z pilotowej oczyszczalni ścieków Gummerwald w Hanowerze (Niemcy). Oba badane modele prognozowały szczytowe stężenia azotu amonowego na poziomie >8 gN/m3 w ciągu, którego obciążenie hydrauliczne wzrastało czterokrotnie w porównaniu do okresu bezdeszczowego. Prognozowany...
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Physico-Chemical Characterization and Biological Tests of Collagen/Silk Fibroin/Chitosan Scaffolds Cross-Linked by Dialdehyde Starch
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Biological Control Potential of Native Entomopathogenic Nematodes (Steinernematidae and Heterorhabditidae) against Mamestra brassicae L. (Lepidoptera: Noctuidae)
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An approach to adaptive beamforming in measurement of EEG.Proceedings 2nd European Medical and Biological Engineering Conference.EMBEC´02.Pt.2
PublicationPotencjały wywołane są wykorzystywane w diagnostyce narządów zmysłu. Ze względu na niski SNR wymagana jest wielokrotne powtarzanie stymulacji i uśrednianie wyników. Prowadzi to do zwielokrotnienia czasu badania. SNR może zostać poprawiony przy użyciu matrycy sensorów. Są one wykorzystane do śledzenia źródeł sygnału. W publikacji przedstawiono dwie metody adaptacyjnego poprawania współczynnika SNR.
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Thin layer headspace gas chromatography for biological monitoring of persons exposed to volatile organohalogen compounds from water
PublicationCelem pracy było zbadanie możliwości wykorzystania analizy fazy nadpowierzchniowej nad cienką warstwą cieczy z samoczynną generacją ciekłego sorbentu (TLHS)do izolacji i wzbogacania THM w próbkach moczu i krwi ludzkiej. Umożliwiło to następnie wykorzystanie prostej techniki bezpośredniego nastrzyku próbki do kolumny chromatografu gazowego, wyposażonego w detektor wychwytu elektronów (DAI-GC-ECD).Przy pomocy tak opracowanej metody...
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Interactions between polyphenolic antioxidants quercetin and naringenin dictate the distinctive redox-related chemical and biological behaviour of their mixtures
PublicationFood synergy concept is suggested to explain observations that isolated antioxidants are less bioactive than real foods containing them. However, mechanisms behind this discrepancy were hardly studied. Here, we demonstrate the profound impact of interactions between two common food flavonoids (individual: aglycones quercetin—Q and naringenin—N− or their glycosides rutin—R and naringin—N+ vs. mixed: QN− and RN+) on their electrochemical...
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Application of ion chromatography with pulsed amperometric detection for the determination of trace cyanide in biological samples, including breast milk
PublicationCyanide (CN) is the biomarker of exposure to the components of tobacco smoke, although its presence in biological samples is also due to the consumption of products containing cyanogenic glycosides. In this work, we determine the concentration of the free cyanide in urine, saliva and breast milk matrices, using ion chromatography with pulsed amperometric detection (IC-PAD). IC-PAD is an emerging method, with only few documented...
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Improving SBR Performance Alongside with Cost Reduction through Optimizing Biological Processes and Dissolved Oxygen Concentration Trajectory
PublicationAuthors of this paper take under investigation the optimization of biological processes during the wastewater treatment in sequencing batch reactor (SBR) plant. A designed optimizing supervisory controller generates the dissolved oxygen (DO) trajectory for the lower level parts of the hierarchical control system. Proper adjustment of this element has an essential impact on the efficiency of the wastewater treatment process as well...
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Strategies for Achieving Energy Neutrality in Biological Nutrient Removal Systems – a Case Study of the Slupsk WWTP (northern Poland)
PublicationThe paper presents a model-based evaluation of technological upgrades on the energy and cost balance in a large biological nutrient removal wastewater treatment plant (WWTP) in the city of Slupsk (northern Poland). The proposed upgrades include chemically enhanced primary sludge removal and reduction of the nitrogen load in the deammonification process employed for reject water treatment. Simulations enabled to estimate the increased...
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Synthesis and biological evaluation of N-acylated tyramine sulfamates containing C-F bonds as steroid sulfatase inhibitors
PublicationSteroid sulfatase (STS) is responsible for the hydrolysis of biologically inactive sulfated steroids into their active un-sulfated forms and promotes the growth of various hormone-dependent cancers (e.g., breast cancer). Therefore, the STS enzyme is a promising therapeutic target for the treatment of steroid-sensitive cancers. Herein, we report the synthesis and biological evaluation of sulfamate analogs as potential STS inhibitors...
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Chromatographic analyses of Lavandula angustifolia and Rosmarinus officinalis extracts and their biological effects in mammalian cells and cell-free systems
PublicationKnowledge of biological properties of natural compounds allows to understand their therapeutic value, efficacy and security. We investigated: composition of Lavandula angustifolia (LA) and Rosmarinus officinalis (RO) extracts, their antioxidant capacity, cytotoxicity and genotoxicity, their DNA-protective potential against DNA damage induced in hamster V79 cells by several genotoxins or in plasmid DNA by Fe2+ ions and activity...
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Strategies for achieving energy neutrality in biological nutrient removal systems - a case study of the Slupsk WWTP (northern Poland)
PublicationThe paper presents a model-based evaluation of technological upgrades on the energy and cost balance in a large biological nutrient removal wastewater treatment plant (WWTP) in the city of Slupsk (northern Poland). The proposed upgrades include chemically enhanced primary sludge removal and reduction of the nitrogen load in the deammonification process employed for reject water treatment. Simulations enabled to estimate the increased...
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Structure, Physicochemical and Biological Properties of an Aqua (2,2′,2′′-Nitrilotriacetato)-oxidovanadium(IV) Salt with 4-Methylpyridinium Cation
PublicationThe crystal structure of a nitrilotriacetate (nta) oxidovanadi-um(IV) salt with 4-methylpyridinium cation, [4-Me(Py)H]+, of [4-Me(Py)H][VO(nta)(H2O)] stoichiometry was determined. The com-plex comprises a discrete mononuclear [VO(nta)(H2O)]–coordinationentity that can be rarely found among other known compounds con-taining nitrilotriacetate oxidovanadium(IV) moieties. The complex wascharacterized by spectroscopic (IR and EPR) methods,...
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Computer-aided analysis of signals from a low-coherence Fabry-Perot interferometer used for measurements of biological samples
PublicationThe aim of the study was to develop an automated computer-aided system for analysis of spectrograms obtained from measurements of biological samples performed with a low-coherence Fabry-Pérot interferometer. Information necessary to determine dispersion characteristics of measured materials can be calculated from the positions of the maxima and minima that are present in their spectra. The main challenge faced during the development...
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Reactions on the surface of the implant under the influence of biofilm
PublicationThe contact of a biomaterial with the biological environment in in vitro and in vivo tests leads to the production of a particular ecosystem in which the active roles perform both, the material surface and the extracellular matrix protein forming a biofilm. Proteins affect cell and bacteria adhesion processes, biological activity of cells and activation of inflammatory response.The knowledge of the reaction mechanisms active on...
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Structure-activity relationship studies on the antimicrobial activity of novel edeine a and d analogues
PublicationOpisano syntezę 4 nowych analogów peptydowego antybiotyku, edeiny a i d z wykorzystaniem klasycznej syntezy w roztworze. Stosowano metodę estrów aktywnych oraz metodę azydową do tworzenia wiązań peptydowych. Zbadano także aktywność przeciwgrzybową i przeciwbakteryjną opisanych połączeń.
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SAUDI JOURNAL OF BIOLOGICAL SCIENCES
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EXPERT OPINION ON BIOLOGICAL THERAPY
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The up-to-date role of biologics for the treatment of chronic lymphocytic leukemia
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BIOLOGICAL INVASIONS
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BIOLOGICAL REVIEWS
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BIOLOGICAL PSYCHOLOGY
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BIOLOGICAL RESEARCH
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BIOLOGICAL LETTERS
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Potential application of ionic liquids in aluminium production - economical and ecological assessment
PublicationTechnologia wytwarzania aluminium stosowana na skale przemysłową oparta jest na elektrodepozycji w ciekłym kriolicie i nosi nazwę procesu Hall-Heroult'a. Technologia ta wymaga wysokich nakładów energii elektrycznej, charakteryzuje się ponadto, szeroko udokumentowanym, negatywnym wpływem na środowisko naturalne. Produkcja aluminium możliwa jest również metodą alternatywną poprzez elektrodepozycję a mieszaniny cieczy jonowych w temperaturze...
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The influence of base oil type on the rheological properties of ecological lubricating greases
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Supercritical Algal Extracts: A Source of Biologically Active Compounds from Nature
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Urban Farming – The Ecological, Spatial and Social Factors of Urban Landscape Transformation
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Theory and Practice of Coarse-Grained Molecular Dynamics of Biologically Important Systems
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Application of Chemical Sensors and Olfactometry Method in Ecological Audits of Degraded Areas
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The Role of Crypto Trading in the Economy, Renewable Energy Consumption and Ecological Degradation
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Adaptability of a socio-ecological system. The case of a polish municipality at risk of flood
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Biologically active compounds based on the carbazole scaffold - synthetic and mechanistic aspects
PublicationDoctoral dissertation is divided into three main parts: introduction, results and discussion and experimental. The introduction is divided into four main parts which describe: 5-hydroxytryptamine receptors, the most popular antidepressants, new compounds based on the carbazole structure with affinity for serotonin receptors, telomeres and telomerase with their functions, telomerase inhibition strategies, carbazoles approved in...
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May Staphylococcus lugdunensis Be an Etiological Factor of Chronic Maxillary Sinuses Infection?
PublicationStaphylococcus lugdunensis is an opportunistic pathogen found in the healthy human skin microbiome bacterial community that is able to cause infections of diverse localization, manifestation, and course, including laryngological infections, such as necrotizing sinusitis. Chronic maxillary sinusitis is a disease present in up to one third of European and American populations, and its etiology is not fully described. Within this...
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Pro-Ecological Activities in Polish Financial Institutions on the Example of Selected Banks
PublicationThe character of the role that banks play in the economy provides them with an opportunity to positively affect the environment on multiple levels. The article aimed at characterizing and evaluating pro-ecological activities occurring in financial institutions in Poland. It compares pro-ecological activities undertaken by three different banks operating on the Polish market: BOŚ Bank SA, BNP Paribas Bank Polska SA and PKO Bank...
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Polymer biodegradable coatings as active substance release systems for urological applications
PublicationCatheter-associated urinary tract infections are the result of catheterization of the bladder. The risk of infection is directly proportional to the length of the bladder catheterization. Bacteria cells have the ability to adhere and create the biofilm on the surface of catheter materials. Bacteria’s biofilm is an extremely beneficial environment of existence for microorganisms. Microorganisms that are an integral part of the biofilm...
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Synthesis and reactivity of O-acyl selenophosphates
PublicationThe synthesis of several new O-acyl selenophosphates were investigated. The stability and reactivity of the products were studied and related to their structure.
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Synthesis and reactivity of O-acyl selenophosphates.
PublicationMieszane bezwodniki kwasów monoselenofosforowych >P(Se)O-C(O)- w zależności od podstawników na atomie fosforu oraz karbonylowym atomie węgla izomeryzują do układów Se-mostkowych >P(O)Se-(O)C- oraz ulegają dekarboksylacji (dekarbonylacji i dekarboksylacji) do estrów Se-alkilowych >P(O)Se-. W eksperymantach krzyżowych następuje wzajemna wymiana grup acylowych pomiędzy cząsteczkami bezwodników.
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Synthesis and reactivity of O-acyl selenophosphates
PublicationPrzeprowadzono syntezę nowych selenofosforanów acylu. Badano stabilność i reaktywność tych bezwodników w odniesieniu do ich struktury.
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Physicochemical profile of Os (III) complexes with pyrazine derivatives: From solution behavior to DNA binding studies and biological assay
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