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Search results for: PALIWO LNG
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Polymeric micelle-mediated delivery of half-sandwich ruthenium(II) complexes with phosphanes derived from fluoroloquinolones for lung adenocarcinoma treatment
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DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublicationImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
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Application of MARKAL model to optimisation of electricity generation structure in Poland in the long-term time horizon Part I - concept of the model
PublicationIn this paper, which inaugurates a series of papers on this subject, a concept is proposed of a power system development model with regard to the technological structure of electricity generation in Poland, in the long-term time perspective – until 2060. The model is based on the mathematical structure of the MARKAL optimization package. The paper presents a brief description of the tool used in the model research. In addition,...
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Evaluati on of long-term start up costs impact on short-term price based operational optimization of a CCGT using MILP
PublicationAn increasing share of the weather-dependent RES generation in the power system leads to the growing importance of flexibility of conventional power plants. They were usually designed for base load operation and it is a challenge to determine the actual long-term cycling costs, which account for an increase in maintenance and overhaul expenditures, increased forced outage rates and shortened life expectancy of the plant and components....
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Combined Long-Period Fiber Grating and Microcavity In-Line Mach–Zehnder Interferometer for Refractive Index Measurements with Limited Cross-Sensitivity
PublicationThis work discusses sensing properties of a long-period grating (LPG) and microcavity in-line Mach–Zehnder interferometer (µIMZI) when both are induced in the same single-mode optical fiber. LPGs were either etched or nanocoated with aluminum oxide (Al2O3) to increase its refractive index (RI) sensitivity up to ≈2000 and 9000 nm/RIU, respectively. The µIMZI was machined using a femtosecond laser as a cylindrical cavity (d = 60...
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Evaluation of long‑term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins
PublicationToxoplasmosis caused by the opportunistic, cosmopolitan protozoan Toxoplasma gondii is one of the most common parasitoses in the world. Although it may prove dangerous or even fatal for immunocompromised individuals, immunoprophylaxis for humans is still nonexistent. Thus, the aim of the current work was to assess the ability of two immunogenic recombinant chimeric T. gondii proteins, SAG2-GRA1-ROP1 (SGR) and SAG1-MIC1-MAG1-GRA2...
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An automated learning model for twitter sentiment analysis using Ranger AdaBelief optimizer based Bidirectional Long Short Term Memory
PublicationSentiment analysis is an automated approach which is utilized in process of analysing textual data to describe public opinion. The sentiment analysis has major role in creating impact in the day-to-day life of individuals. However, a precise interpretation of text still relies as a major concern in classifying sentiment. So, this research introduced Bidirectional Long Short Term Memory with Ranger AdaBelief Optimizer (Bi-LSTM RAO)...
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Combined anticancer therapy with imidazoacridinone analogue C‐1305 and paclitaxel in human lung and colon cancer xenografts—Modulation of tumour angiogenesis
PublicationThe acridanone derivative 5-dimethylaminopropylamino- 8- hydroxytriazoloacridinone (C-1305) has been described as a potent inhibitor of cancer cell growth. Its mechanism of action in in vitro conditions was attributed, among others, to its ability to bind and stabilize the microtubule network and subsequently exhibit its tumour- suppressive effects in synergy with paclitaxel (PTX). Therefore, the objective of the present study...
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PRELIMINARY FIELD TESTS AND LONG-TERM MONITORING AS A METHOD OF DESIGN RISK MITIGATION: A CASE STUDY OF GDAŃSK DEEPWATER CONTAINER TERMINAL
PublicationAppropriate risk assessment plays a fundamental role in the design. . The authors propose a possible method of design risk mitigation, which follows recommendations included in Eurocode 7. The so-called “Observational Method” (OM) can produce savings in costs and programmes on engineering projects without compromising safety. The case study presented is a complex design solution that deals with the heavy foundations of a gantry...
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The issue of uncertainty of visual measurement techniques for long distance measurements based on the example of applying electric traction elements in diagnostics and monitoring
PublicationRail transport is the most economical and energy-effective in the field of land transport, in particular electrified. In order to ensure efficient and reliable operation of electrified rail transport, the issues of monitoring and diagnostics of the traction infrastructure and vehicles are extremely important. The most critical point in the transmission of electric energy to the vehicle is the sliding contact of the current collector...
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Long range molecular dynamics study of interactions of the eukaryotic glucosamine-6-phosphate synthase with fructose-6-phosphate and UDP-GlcNAc
PublicationGlucosamine-6-phosphate synthase (EC 2.6.1.16) is responsible for catalysis of the first and practically irreversible step in hexosamine metabolism. The final product of this pathway, uridine 5 diphospho Nacetyl- d-glucosamine (UDP-GlcNAc), is an essential substrate for assembly of bacterial and fungal cell walls. Moreover, the enzyme is involved in phenomenon of hexosamine induced insulin resistance in type II diabetes, which...
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MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity in long-term survivors of acute lymphoblastic leukemia treated with doxorubicin
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Fasting Normoglycemia after Intravenous Thrombolysis Predicts Favorable Long-Term Outcome in Non-Diabetic Patients with Acute Ischemic Stroke
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Prediction of CO2 emissions of a car using the discrete map of the operating conditions
PublicationW pracy przedstawiono propozycję opisu warunków eksploatacji pojazdów w wybranej aglomeracji miejskiej z użyciem dyskretnej mapy warunków eksploatacji. Mapa taka umożliwia prognozowanie wybranych parametrów eksploatacyjnych pojazdów dla przyjętych dróg przejazdu oraz różnych jednostek napędowych. Głównymi parametrami wyznaczanymi z użyciem dyskretnej mapy warunków eksploatacji są: całkowita energia przeznaczana do napędu wybranego...
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Anode supported single chamber solid oxide fuel cell in CH4-Air Mixture.
PublicationW tej pracy przedstawiono wyniki prac ogniw paliwowych na bazie elektrolitu z tlenku cyrkonu stabilizowanego itrem o grubości 1-2um wytworzonego na podłożu cermetu z tlenku niklu i tlenku cyrkonu stabilizowanego itrem. LSCF był wykorzystany jako katoda. Ogniwo paliwowe było testowane w konfiguracji jednokomorowej w mieszaninie powietrza i metanu. Uzyskano napięcie o wartości 0.8V, zaś moc wynosiła 0.12W/cm2. Zbdadano wpływ przepływu...
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The carrier capture and recombination processes in Ln/sup 3+/-activated scintillators
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Determination of the bearing capacity of pile foundations based on CPT test results
PublicationAnalityczne określanie pełnej krzywej obciążenie - osiadanie na podstawie parametrów geotechnicznych wciąż stanowi bardzo trudne zadanie naukowe i inżynierskie. W pracy przedstawiono metodę bezpośredniego wykorzystania oporów na stożku sondy statycznej do określania pełnej krzywej osiadania dla pali Vibro-Fundex. W sumie jako materiał weryfikacyjny wykorzystano 94 próbne obciążenia statyczne pali.
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The influence of changes of soil parameters due to consolidation on the interaction of piles and soft soil layer
PublicationZaprezentowano problem wyznaczania bocznego parcia gruntu o małej wytrzymałości na pale. Opisano przypadki występowania bocznego obciążenia pali. Scharakteryzowano właściwości i zachowanie gruntów słabych stanowiących warstwę podłoża o małej wytrzymałości. Zaprezentowano propozycje obliczania bocznego parcia według różnych autorów. Przedstawiono wpływ konsolidacji na zmianę wytrzymałości gruntów słabych w czasie oraz na obliczanie...
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The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension
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The flow of nitrogen into the euphotic zone of the Baltic Proper as a result of the vertical migration of phytoplankton: An analysis of the long-term observations and ecohydrodynamic model simulation
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Application of biocompatible and ultrastable superparamagnetic iron(iii) oxide nanoparticles doped with magnesium for efficient magnetic fluid hyperthermia in lung cancer cells
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The Effects of Slaughter Age and Sex on Carcass Traits, Meat Quality, and Leg Bone Characteristics of Farmed Common Pheasants (Phasianus colchicus L.)
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Correction to: The Operative management in Bariatric Acute abdomen (OBA) Survey: long-term complications of bariatric surgery and the emergency surgeon’s point of view
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An assessment of regulated emissions and CO2 emissions from a European light-duty CNG-fueled vehicle in the context of Euro 6 emissions regulations
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Comparison of peptide cancer signatures identified by mass spectrometry in serum of patients with head and neck, lung and colorectal cancers: Association with tumor progression
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Late subclinical hemolysis and long-term outcomes after aortic valve replacement with On-X mechanical prostheses – a preliminary single-center report
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Epithelium morphogenesis and oviduct development are regulated by significant increase of expression of genes after long-term in vitro primary culture – a microarray assays
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‘Heart development and morphogenesis’ is a novel pathway for human ovarian granulosa cell differentiation during long‑term in�vitro cultivation‑a microarray approach
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Fatty Acids Related Genes Expression Undergo Substantial Changes in Porcine Oviductal Epithelial Cells During Long-Term Primary Culture
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Safe-by-Design Ligand-Coated ZnO Nanocrystals Engineered by an Organometallic Approach: Unique Physicochemical Properties and Low Toxicity toward Lung Cells
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Application of MARKAL model to optimisation of electricity generation structure in Poland in the long-term time horizon. Part II. Model and forecasts assumptions
PublicationIn this paper, the next in a series of publications on the subject, assumptions are presented of a power system development model in terms of electricity generation technology infrastructure in Poland, in the long term perspective until 2060. The model is based on the mathematical structure of the MARKAL optimization package. Among other things developed are a forecast of the final demand for electricity and heat, the current...
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c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells
PublicationUnsymmetrical bisacridines (UAs) are highly active antitumor compounds. They contain in their structure the drugs previously synthesized in our Department: C-1311 and C-1748. UAs exhibit different properties than their monomer components. They do not intercalate to dsDNA but stabilize the G-quadruplex structures, particularly those of the MYC and KRAS genes. Since MYC and KRAS are often mutated and constitutively expressed in cancer...
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Cellular Effects of Selected Unsymmetrical Bisacridines on the Multicellular Tumor Spheroids of HCT116 Colon and A549 Lung Cancer Cells in Comparison to Monolayer Cultures
PublicationMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), which are responsible for cancer progression, metastasis, and recurrence. Therefore, we applied this model in our studies of highly active antitumor unsymmetrical bisacridines (UAs). We investigated the cellular response induced by UAs in 2D and 3D cultures of HCT116 colon and A549 lung cancer...
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Corrigendum to “An investigation on residual stress and fatigue life assessment of T-shape welded joints” [Eng. Fail. Anal. 141 (2022) 106685]
PublicationThis paper aims to quantitatively evaluate the residual stress and fatigue life of T-type welded joints with a multi-pass weld in different direction. The main research objectives of the experimental test were to test the residual stress by changing direction along with multiple wielding passes and determine the fatigue life of the welded joints. The result shows that compressive residual stress increases in the sample gradually...
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Physiological Biomarkers Assessed by Low‐Tech Exercise Tests Predict Complications and Overall Survival in Patients Undergoing Pneumonectomy Due to Lung Cancer
PublicationDue to its debilitating character pneumonectomy this is last‐resort procedure. Preoperative results of the 6‐min walking test (6MWT) help to identify high risk of postoperative complications and increased mortality in patients undergoing lobectomy for lung cancer. The aim of the study was to validate the value of 500 m in 6MWT as an indicator, which differentiates risk of complications in patients undergoing pneumonectomy. 125...
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The efficiency and technological reliability of biogenic compounds removal during long-term operation of a one-stage subsurface horizontal flow constructed wetland
PublicationThe paper presents the results of a study of the efficiency and technological reliability of total nitrogen and total phosphorus removal during long term operation of a one-stage constructed wetland system with subsurface horizontal wastewater flow. The flow rate of the wastewater treatment plant was 1.2m3/d during the research period. Physical and chemical analyses of raw wastewater and treated effluent were carried out in the...
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Quantum dots conjugates with unsymmetrical bisacridines enhance cytotoxicity of these antitumor compounds in lung cancer cells and have protecting effects on normal cells
PublicationBackground: In recent years, with the rapid development of nanotechnology and its extensive applications in the medicine, nanocarriers for anticancer drug delivery have gained a great importance. Spherical semiconductor nanocrystals, frequently called quantum dots (QDs) are very attractive nanomaterials for bioimaging applications and they possess properties as potential candidates for drug carrier. Unsymmetrical bisacridines (UAs),...
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"Raport z wstępnych badań własności stali trudnościeralnej 460HB",. ang "Report on preliminary tests of the properties of wear-resistant steel 460HB"
PublicationMikrostrukturę badanej stali trudnościeralnej 460HB stanowi drobnoziarnisty martenzyt odpuszczony, który jest właściwy dla stali konstrukcyjnych niskowęglowych, niskostopowych ulepszonych cieplnie. W przypadku blach grubych, do których zalicza się badana stal, struktura może ulec zaburzeniu, jeżeli w hutniczym procesie wytwórczym wystąpiła niejednorodność odkształcenia plastycznego i w konsekwencji tworzenie się pasm segregacyjnych,...
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Badania statyczne i dynamiczne pali wierconych. Przebudowa drogi krajowej nr 7 na obwodnicy Grójca.
PublicationPraca obejmowała wykonanie 4 opinii dotyczących nośności pali wierconych o średnicy 600 mm, 1000 mm i 1500 pod podpory obiektów w ciągu obwodnicy Grójca na podstawie badań statyczny i dynamicznych. W ramach umowy wykonano 5 obciążeń statycznych.
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Rzeczywista nośność pali w gruntach ilastych z zastosowaniem zaleceń PN-EN 1997-1:2004
PublicationObecnie co raz więcej obiektów posadawianych jest w gruntach słabych bądź o specyficznych parametrach, do takich gruntów zalicza się iły. Jedną z podstawowych możliwości posadowienia w gruntach ilastych jest posadowienie na palach. Projektowanie fundamentów na palach dla takich warunków wymaga specjalnego i indywidualnego podejścia. W pracy przedstawiono przegląd metod i uwag w oparciu o PN-EN 1997-1:2004, którymi należy kierować...
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Ocena nośności pali wierconych fi 880 mm wykonanych pod posadowienie podpór wiaduktu na podstawie próbnych obciążeń statycznych pali. Budowa wiaduktu nad torami PKP relacji Gdańsk - Tczew (E-65) w km 310+773.
PublicationWykonano ocenę nośności fundamentów palowych posadowionych na palach wierconych o średnicy 880 mm na podstawie badań statycznych tych pali.
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Impedance spectroscopy as a diagnostic tool of degradation of Solid Oxide Fuel Cells = Spektroskopia impedancyjna jako narzędzie diagnostyczne degradacji tlenkowych ogniw paliwowych
PublicationTlenkowe ogniwa paliwowe SOFC sa obecnie bliskie komercjalizacji. Wiedza na temat mechanizmów degradacji ogniw paliwowych jest niezbędna do dalszej poprawy ich działania. Spektroskopia impedancyjna jest skutecznym narzędziem diagnostycznym. Pozwala ona na wskazanie który element ogniwa SOFC ulega pogorszeniu oraz pozwala poznać dokładniej naturę procesu degradacji. W tej pracy degradacja ogniwa SOFC została zbadana przy użyciu...
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Estimation of autotrophic maximum specific growth rate constant-experience from the long-term operation of a laboratory-scale Sequencing Batch Reactor System
PublicationW pracy wykorzystano wyniki badań z długookresowej eksploatacji laboratoryjnego reaktora typu SBR do estymacji stałej szybkości przyrostu bakterii nitryfikacyjnych. Badania obejmowały zarówno pomiary empiryczne (doświadczenia przy niskim stosunku substratu do biomasy) oraz symulacje komputerowe. Do symulacji dynamicznych wykorzystano jedną wartość współczynnika = 1,2 1/d, pomimo różnych wartości mierzonych jednostkowych szybkości...
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Comparison of oral-health-related quality of life in patients in the short- and long-term period following lower-facial injury and fractures – preliminary report
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Regulated and Unregulated Exhaust Emissions from CNG Fueled Vehicles in Light of Euro 6 Regulations and the New WLTP/GTR 15 Test Procedure
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Interferon lambda polymorphisms associate with body iron indices and hepatic expression of interferon-responsive long non-coding RNA in chronic hepatitis C
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Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial
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The Influence of Long-Term Heat Treatment on Microstructure of Zr-Modified Aluminide Coating Deposited by CVD Method on MAR M200+Hf Nickel Superalloy
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New Gene Markers for Metabolic Processes and Homeostasis in Porcine Buccal Pouch Mucosa during Cells Long Term-Cultivation—A Primary Culture Approach
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Recidivism Rate among patients discharged from long care unit in forensic psychiatry program at Mental Health Hospital, Taif, Saudi Arabia
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