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Search results for: PHAGE THERAPY
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Gemcitabine Peptide-Based Conjugates and Their Application in Targeted Tumor Therapy
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Bacteriophages as potential tools for use in antimicrobial therapy and vaccine development
PublicationThe constantly growing number of people suffering from bacterial, viral, or fungal infections, parasitic diseases, and cancers prompts the search for innovative methods of disease prevention and treatment, especially based on vaccines and targeted therapy. An additional problem is the global threat to humanity resulting from the increasing resistance of bacteria to commonly used antibiotics. Conventional vaccines based on bacteria...
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Inhibitory mikrotubul w terapii przeciwnowotworowej = Inhibitors of microtubule in cancer therapy
PublicationW artykule opisano inhibitory mikrotubul, różnorodne związki chemiczne, znajdujące się w zaawansowanych przedklinicznych i wstępnych badaniach klinicznych. Pośród nich na uwagę zasługują półsyntetyczne analogi taksolu, substancje pochodzenia naturalnego, takie jak: epotilony, kombretastatyny, kolchinoidy, dolastatyny oraz syntetyczne związki o niskim ciężarze czasteczkowym: heterokombretastatyny, sulfonamidy, fenostatyny, pochodne...
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Smart Pen - new multimodal computer control tool for graphomotorical therapy
PublicationW sytuacji, gdy około 15% populacji uczniów wykazuje cechy dyslektyczne, koniecznością staje się wyposażenie szkół w efektywne narzędzia do diagnozy i terapii tego rodzaju zaburzeń. Dzięki wykorzystaniu tabletu i specjalnie skonstruowanego długopisu wyposażonego w czujniki nacisku uzyskano możliwość monitorowania wielu parametrów, które do tej pory były dla terapeutów całkowicie niedostępne (np. pomiar nacisku na podłoże czy ścisku...
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Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy
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Dual-task exercise as a therapy for executive motor function in Parkinson’s disease
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Tinnitus Therapy Based on High-Frequency Linearization Principles - Preliminary Results
PublicationThe aim of this work is to present problems related to tinnitus symptoms, its pathogenesis, hypotheses on tinnitus causes, and therapy treatment to reduce or mask the phantom noise. In addition, the hypothesis on the existence of parasitic quantization that accompanies hearing loss has been recalled. Moreover, the paper describes a study carried out by the Authors with the application of high-frequency dither having specially formed...
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Effect of brefeldin A and castanospermine on resistant cell lines as supplements in anticancer therapy
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Investigation of photothermolysis therapy of human skin diseases using optical phantoms
PublicationDermatological diseases, such as neurofibroma (Recklinghausen disease) or hemangiomas can be efficiently treated using photothermolysis from laser irradiation. We have utilized a developed 975 nm fiber diode laser as a low-cost alternative over common Nd:YAG lasers. This paper describes the investigations of interaction of 975 nm diode laser radiation-pulses with optical skin phantoms which were designed and manufactured in our...
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Effect of renal replacement therapy on selected arachidonic acid derivatives concentration
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Theophylline Therapy for Near-Fatal Cheyne–Stokes Respiration: A Case Report
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Radiation therapy dosimetry using magnetic resonance imaging of polymer gels
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Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublicationDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
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Possiblities of application of recombined lysostaphin as an alternative agent in the therapy of Staphylococcus aureus mastitis
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Binocular Vision Impairments Therapy Supported By Contactless Eye-gaze Tracking System
PublicationBinocular vision impairments often result in partial or total loss of stereoscopic vision. The lack of binocular vision is a serious vision impairment that deserves more attention. Very important result of the binocular vision impairments is a binocular depth perception. This paper describes also a concept of a measurement and therapy system for the binocular vision impairments by using eye-gaze tracking system.
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Photophysical properties and photocytotoxicity of novel phthalocyanines – potentially useful for their application in photodynamic therapy
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Therapy with CD4+CD25+ T regulatory cells – should we be afraid of cancer?
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Reasons for the discontinuation of therapy of personal insulin pump in children with type 1 diabetes
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Radiation Therapy-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
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Recent progress in the engineering of multifunctional colloidal nanoparticles for enhanced photodynamic therapy and bioimaging
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Serum MicroRNAs as Xerostomia Biomarkers in Patients With Oropharyngeal Cancer Undergoing Radiation Therapy
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Selection of physiological parameters for optoelectronic system supporting behavioral therapy of autistic children
PublicationIn this article the procedure of selection of physiological parameters for optoelectronic system supporting behavioral therapy of autistic children is proposed. Authors designed and conducted an experiment in which a group of 30 health volunteers (16 females and 14 males) were examined. Under controlled conditions people were exposed to a stressful situation caused by the picture or sound (1kHz constant sound, which was gradually...
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More is Less? Optimal Combination Therapy for Adequate Blood Pressure Lowering in Hypertension
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Potential application of pure silica optical flat fibers for radiation therapy dosimetry
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Investigating the disease‐modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
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Limiting futile therapy as part of end-of-life care in intensive care units
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Surfactant replacement therapy as promising treatment for COVID-19: an updated narrative review
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Application of the laser diode with central wavelength 975 nm for the therapy of neurofibroma and hemangiomas
PublicationThis paper presents newly developed dermatological laser (with central wavelength 975 nm) for application in therapies requiring deep penetration of tissue, e.g. cutaneous (dermal) neurofibroma (Recklinghausen disease) and hemangiomas. This laser can work either in pulse or continues wave mode. Laser radiation is transmitted toward the application region by optical fiber with a diameter of 0.6 mm. The compact design of the laser...
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Investigating the disease- modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
PublicationAlzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day-to-day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability....
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Antimicrobial photodynamic therapy with fulleropyrrolidine: photoinactivation mechanism of Staphylococcus aureus, in vitro and in vivo studies
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Murine Model Imitating Chronic Wound Infections for Evaluation of Antimicrobial Photodynamic Therapy Efficacy
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Combination of therapy with 5-fluorouracil and cisplatin with electroporation in human ovarian carcinoma model in vitro
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Adoptive Cell Therapy—Harnessing Antigen-Specific T Cells to Target Solid Tumours
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Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy
PublicationSkin lesions are commonly treated using laser heating. However, the introduction of new devices into clinical practice requires evaluation of their performance. This study presents the application of optical phantoms for assessment of a newly developed 975-nm pulsed diode laser system for dermatological purposes. Such phantoms closely mimic the absorption and scattering of real human skin (although not precisely in relation to...
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Surface Modification of Nanocrystalline TiO2 Materials with Sulfonated Porphyrins for Visible Light Antimicrobial Therapy
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Beta‐blockers as sub‐optimal treatment for hypertension: Time for first‐line therapy revision?
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Biological and psychological components of depression in patients receiving IFN-alpha therapy for hepatitis C
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Clot Lysis Time Predicts Stroke During Anticoagulant Therapy in Patients with Atrial Fibrillation
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Skin cancer, including related pathways and therapy and the role of luteolin derivatives as potential therapeutics
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Cardiovascular risk and response to lipid lowering therapy in patients with HIV infection according to different recommendations
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T-House. Shaping Ergonomic and Flexible Interiors in Modular Form Connected to Horticultural Therapy Zone
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Molecular modeling and evaluation of novel dibenzopyrrole derivatives as telomerase inhibitors and potential drug for cancer therapy
PublicationDuring previous years, many studies on synthesis, as well as on anti-tumor, anti-inflammatory and anti-bacterial activities of the pyrazole derivatives have been described. Certain pyrazole derivatives exhibit important pharmacological activities and have proved to be useful template in drug research. Considering importance of pyrazole template, in current work the series of novel inhibitors were designed by replacing central...
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Prospective assessment of continuous subcutaneous insulin infusion therapy in young children with type 1 diabetes
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Dendrimer based theranostic nanostructures for combined chemo- and photothermal therapy of liver cancer cells in vitro
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Maintenance therapy with everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis (the EMINENTS study)
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Positive electrostatic therapy of metastatic tumors: selective induction of apoptosis in cancer cells by pure charges
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Efficacy of the Whole-Body Cryotherapy as Add-on Therapy to Pharmacological Treatment of Depression—A Randomized Controlled Trial
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The impact of an electronic monitoring and reminder device on patient compliance with antihypertensive therapy: a randomized controlled trial
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