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Search results for: ANIMAL EXPERIMENTATION
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Between therapy effect and false-positive result in animal experimentation
PublicationDespite the animal models’ complexity, researchers tend to reduce the number of animals in experiments for expenses and ethical concerns. This tendency makes the risk of false-positive results, as statistical significance, the primary criterion to validate findings, often fails if testing small samples. This study aims to highlight such risks using an example from experimental regenerative therapy and propose a machine-learning...
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Bioaccumulation of metals in tissues of marine animals, Part II - metal concentrations in animal tissues
PublicationThe bioaccumulation of metals in an animal depends on a multitude of factors: biotic ones, like its body dimensions and mass, age, sex, diet, metabolism and position in the trophic web, as well as abiotic ones such as the distribution of metals in its environment, the salinity, temperature and pH of the water, habitat type, interactions with other metals. But it is diet that has the greatest influence on the accumulation of metals...
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Minimal and maximal solutions of differential equations with a singularmatrix.
PublicationPraca dotyczy zagadnień początkowych dla układów równań różniczkowych z macierzą osobliwą. Równania różniczkowo-algebraiczne są szczególnym przypadkiem takich zagadnień.Stosując metodę iteracji monotonicznych pokazano, że przy pewnych założeniach problem wyjściowy ma ekstremalne rozwiązania w pewnym sektorze.Teoretyczne rozważania zilustrowano przykładem.
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Mixed systems with minimal and maximal lifetime variances
PublicationRozważa się mieszane układy złożone ze stałej liczby składników, których czasy zycia są niezależnymi zmiennymi losowymi o jednakowym rozkładzie i dodatniej wariancji. Bada się minimalną i maksymalną wariancję czasu życia rozważanych układów.
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Improving performance of large thrust bearings through modeling and experimentation
PublicationLarge thrust bearings are highly loaded machine elements and their failures cause serious losses. Start ups and stoppages of the bearing under load are specially critical regimes of operation. Load carrying capacity depends on the profile of the oil gap. In transient states this profile is also changing. In the design of large thrust bearings minimizing thermo-elastic deformations is an important goal, which can be accomplished...
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Experimentation, material modelling and simulation of bonded joints with a flexible adhesive
PublicationThe paper deals with material parameters identification of a flexible adhesive and the numerical simulation of its behaviour in a single lap bonded joint. The material modelling was based on the simple shear and tensile-shear laboratory tests of the bonded joints made of thin aluminium and polyurethane plates with the flexible adhesive Terostat MS 9360 manufactured by Henkel AG & Co. The adhesive was considered as a hyperelastic...
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NUMERICAL MODELLING AND EXPERIMENTATION OF HISTORICAL CARPENTRY CORNER LOG JOINTS
PublicationThe main purpose of this research is to determine the stress distributions on the contact surfaces between the logs of the historical carpentry corner joints. The additional purpose is to compare the stress distribution for four different boundary conditions in the case of dry and wet pine wood. The paper presents the results of numerical analysis of the shortcorner dovetail connection and the saddle notch corner joint, which are...
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Quasi-controlled Experimentations on the Impact of AOP on Software Comprehensibility
PublicationAspect-oriented programming (AOP) emerged as a paradigm to modularize the concerns that lead to interwoven code if implemented using traditional programming techniques. Unfortunately, the new constructs introduced by aspect-oriented (AO) languages result in both: (1) obstacles in modular reasoning, and (2) high coupling between aspects and the augmented modules. There have been numerous attempts to tackle these issues, but none...
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Deformation Behavior and Microstructural Evolution during Hot Stamping of TA15 Sheets: Experimentation and Modelling
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Zwierzęce szczątki kostne / Animal remains
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Antithrombotic Potential of Tormentil Extract in Animal Models
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The Use of Bacteriophages in Animal Health and Food Protection
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Wpływ odkształcenia na parametry stereometryczne powłok z faz międzymetalicznych NiAl i Ni3Al = Strain intensity effect on stereometrical properties at the NiAl i Ni3Al coating
PublicationWspółcześnie materiały na osnowie faz międzymetalicznych są przedmiotem badań wielu ośrodków naukowo-badawczych w kraju.Stopy na osnowie uporządkowanych faz międzymetalicznych z udziałem aluminium posiadają dużą odporność na utlenianie i korozję wżerową, a także wysoką wytrzymałość zmęczeniową oraz żaroodporność. Dlatego znalazły one zastosowanie do produkcji części maszyn do pracy w trudnych warunkach eksploatacyjnych (łopatki...
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Exposure to PBDEs associated with farm animal meat consumption
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Procognitive activity of nitric oxide inhibitors and donors in animal models
PublicationNitric oxide is a small gaseous molecule that plays important roles in the majority of biological functions. Impairments of NO-related pathways contribute to the majority of neurological disorders, such as Alzheimer’s disease (AD), and mental disorders, such as schizophrenia. Cognitive decline is one of the most serious impairments accompanying both AD and schizophrenia. In the present study, the activities of NO donors, slow (spermine...
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Comparison of Tracking Methods in Respect of Automation of Animal Behavioral Test
PublicationAutomation in experiments carried out on animals is getting more and more important in research. Computers take over laborious and time-consuming activities like recording and analysing images of experiment scene. The first step in an image analysis is finding and distinguishing between the observed animals, and then tracking all objects during the experiment. In this paper four tracking methods are presented. Quantitative and...
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Terrestrial animal livers as a source of PCDD/Fs, PCBs and PBDEs in the diet
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Effect of the Unit Pressure on the Selection Parameters of Intermetallic Coastings NiAl and Ni3Al after Platic Working
PublicationW artykule omówiono wpływ zgniotu na wybrane parametry warstwy międzymetalicznej NiAl i Ni3Al napawanej na stali C45 podanej obróbce plastycznej poprzez prasowanie na zimno.
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Decision classification criteria for ADT in burn diagnostics based on in-vivo animal experiments
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Interactions of Bacteriophages with Animal and Human Organisms—Safety Issues in the Light of Phage Therapy
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Determination of Selected Organic Acids in Animal Farm Water Samples by Ion Chromatography
PublicationLow molecular mass carboxylic acids (LCAs) occur in many environmental compartments due to natural processes and human activity. They are an important group of organic pollutants of waste water that mainly includes, volatile fatty acids, and also dicarboxylic, aromatic, hydroxy- and ketoacids. LCAs are present in the environment at concentrations between 1 to 5000 ppm and different methods have been reported for their determination...
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Reproductive Consequences of Electrolyte Disturbances in Domestic Animals
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The Character of Animal Exploitation and the Environment at the Polish/Prussian Frontier in the Medieval Period: A Case Study
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Improved chromatography separation for polybrominated diphenyl ether congeners quantification in the food of animal origin
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A cortex-like model for animal recognition based on texture using feature-selective hashing
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An animal model of the procognitive properties of cysteine protease inhibitor and immunomodulatory peptides based on colostrum.
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A new animal model of (chronic) depression induced by repeated and intermittent lipopolysaccharide administration for 4months
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Investigations On Water Circulation in Animal Sea-Water Basins – On the Example of Seals′ Breeding Pools
PublicationThis paper presents general comments concerning investigations on water circulation in animal breeding pools containing sea water. As an example are given results of computer simulation of water circulation in seals’ breeding pools situated in Marine Station at Hel, belonging to Oceanographic Institute, Gdansk University. A mathematical model of three main pools was prepared with taking into account their inflow and outflow water...
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Deep Instance Segmentation of Laboratory Animals in Thermal Images
PublicationIn this paper we focus on the role of deep instance segmentation of laboratory rodents in thermal images. Thermal imaging is very suitable to observe the behaviour of laboratory animals, especially in low light conditions. It is an non-intrusive method allowing to monitor the activity of animals and potentially observe some physiological changes expressed in dynamic thermal patterns. The analysis of the recorded sequence of thermal...
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What defines excellent lighting design for humans and animals?
PublicationWhat defines excellent lighting design for humans and animals? The answer to the above question is more than complex. It is not enough nowadays to design a project to make it aesthetically pleasing. Nor is it sufficient to create nicely lit environments, or simply to achieve the light levels required by the lighting norms or standards. With the new scientific research of the last few decades that relates directly or indirectly...
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Serum trace elements in animal models and human depression: Part III. Magnesium. Relationship with copper
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Negative psychological aspects of working with experimental animals in scientific research
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Aquaporin-2 water channel in the kidney of farm animals: An overview
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Linezolid-Resistant Enterococcus spp. Isolates from Foods of Animal Origin—The Genetic Basis of Acquired Resistance
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Production, Transformation and Determination of Volatile Fatty Acids in Farm Animals and the Environment
PublicationThe paper is a critical discussion of the production, transportation and determination of volatile fatty acids in rumens of ruminants. The odor nuisance of the emission of VFAs, often accompanied by volatile nitrogen- and sulfur-organic compounds from animal farming is also discussed.
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Toxoplasma gondii Recombinant Antigens in the Serodiagnosis of Toxoplasmosis in Domestic and Farm Animals
PublicationToxoplasmosis is caused by an intracellular protozoan, Toxoplasma gondii, and is a parasitic disease that occurs in all warm-blooded animals, including humans. Toxoplasmosis is one of the most common parasitic diseases of animals and results in reproductive losses. Toxoplasmosis in humans is usually caused by eating raw or undercooked meat or consuming dairy products containing the parasite. Diagnosis of toxoplasmosis is currently...
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Deep learning based thermal image segmentation for laboratory animals tracking
PublicationAutomated systems for behaviour classification of laboratory animals are an attractive alternative to manual scoring. However, the proper animals separation and tracking, especially when they are in close contact, is the bottleneck of the behaviour analysis systems. In this paper, we propose a method for the segmentation of thermal images of laboratory rats that are in close contact during social behaviour tests. For this, we are...
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Human Wharton’s Jelly—Cellular Specificity, Stemness Potency, Animal Models, and Current Application in Human Clinical Trials
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Preliminary performance evaluation of a high resolution small animal PET scanner with monolithic crystals and depth-of-interaction encoding
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Is there a low-risk anomaly across countries?
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Minimal 2-dominating sets in Trees
PublicationWe provide an algorithm for listing all minimal 2-dominating sets of a tree of order n in time O(1.3247^n). This leads to that every tree has at most 1.3247^n minimal 2-dominating sets. We also show that thisbound is tight.
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Vehicle detector training with minimal supervision
PublicationRecently many efficient object detectors based on convolutional neural networks (CNN) have been developed and they achieved impressive performance on many computer vision tasks. However, in order to achieve practical results, CNNs require really large annotated datasets for training. While many such databases are available, many of them can only be used for research purposes. Also some problems exist where such datasets are not...
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Minimal double dominating sets in trees
PublicationWe provide an algorithm for listing all minimal double dominating sets of a tree of order $n$ in time $\mathcal{O}(1.3248^n)$. This implies that every tree has at most $1.3248^n$ minimal double dominating sets. We also show that this bound is tight.
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Clinical Application of Bioextracts in Supporting the Reproductive System of Animals and Humans: Potential and Limitations
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Automatic analysis of the aggressive behavior of laboratory animals using thermal video processing
PublicationThe bite detection is very important but difficult element of the social interaction analysis. Standard observation methods like human observer or a camcorder of visible light frequencies fail in this case. However, it is possible to discern cooler spots on the rodent's body that appear after body contact with another individual, and vanish after short time. These spots are assumed to be a saliva trace left on fur after bite. In...
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Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy—From Animal Models to Clinical Trials
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Polybrominated diphenyl ethers (PBDEs) in raw milk from different animal species and in infant formula. Occurrence and risk assessment
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The Effect of Diets Containing High-Moisture Corn or Triticale Grain on Animal Performance and the Fatty Acid Composition of Lamb Muscles
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Future opportunities for products derived from black soldier fly (BSF) treatment as animal feed and fertilizer - A systematic review
PublicationThe pursuit of novel food products with good nutritional value for both direct and indirect human consumption is crucial. Given the nutritional benefits of insects and the sustainability of this sort of farming, using them as food for farmed animals is a promising alternative. In this regard, the black soldier fly (Hermetia illucens) is most capable of efficiently converting a wide variety of organic materials, from food waste...
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The New 3D Printed Left Atrial Appendage Closure with a Novel Holdfast Device: A Pre-Clinical Feasibility Animal Study
PublicationMany patients undergoing cardiac surgery have risk factors for both atrial fibrillation and stroke. The left atrial appendage (LAA) is the primary site for thrombi formation. Therefore LAA occlusion devices should be tested for their ability to reduce future cerebral ischemic events in patients with high-risk of haemorrhage. The aim of this study was to evaluate the safety and feasibility of a novel left atrial appendage exclusion...