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Wyniki wyszukiwania dla: HUMAN EXPOSURE
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Effects of five sulphonamides on duckweed (Lemna minor) after prolonged exposure time and their dependency on photoradiation
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Inhalation risk to PAHs and BTEX during barbecuing: The role of fuel/food type and route of exposure
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Effect of previous lowering of skin temperature on the time of safe exposure to a hot environment: a case study
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Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis
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Intensification of bacterial cellulose production process with sequential electromagnetic field exposure aided by dynamic modelling
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Determining the noise impact on hearing using psychoacoustical noise dosimeter
PublikacjaThis research study presents the designed noise dosimeter based on psychoacoustical properties of the human hearing system and, at the same time. evaluation of time and frequency characteristics of noise. The designed noise dosimeter enables assessing temporary threshold shift (TTS) in critical hands in real time. In this way it is possible monitoring the hearing threshold shift continuously for people who stay in the harmful noise...
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Brain circuit imprints of developmental 17α-Ethinylestradiol exposure in guppies (Poecilia reticulata): Persistent effects on anxiety but not on reproductive behaviour
PublikacjaThe effects of endocrine disruptors may vary with the timing of exposure. The physiological implications of adult exposure are present during and shortly after exposure while embryonic exposure can imprint changes manifested in adulthood. In this study, guppy (Poecilia reticulata) embryos were exposed to 2 and 20 ng/L of 17α-ethinylestradiol during development via the mother and reared in clean water from gestation until 6 months...
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Exploring avian exposure to parent polycyclic aromatic hydrocarbons (PAHs): Using the common eider Somateria mollissima in a global context
PublikacjaCompared to other organic contaminants, birds are rarely studied for their exposure to polycyclic aromatic hydrocarbons (PAHs), mainly due to their effective metabolization of parent PAHs. However, as some studies suggest, exposure to PAHs may result in adverse health effects including decreased survival, especially following oil spills. In the present study, we analyzed samples from a sea duck, the common eider Somateria mollissima...
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Daily diet containing canned products significantly increases serum concentrations of endocrine disruptor bisphenol A in young women
PublikacjaNowadays, exposure to environmental factors is considered to be one of the possible causes of several lifestyle diseases, such as obesity, type 2 diabetes, cardiovascular disease, and cancer. Particularly noteworthy are endocrine‑disrupting chemicals (EDCs), which affect the metabolism of hormones and interact with their receptors, thus exerting adverse health effects. One of the most ubiquitous EDC in daily life is bisphenol A...
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Serum miRNA-based signature indicates radiation exposure and dose in humans: a multicenter diagnostic biomarker study
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Occurrence of Breast Cancer in the Population of Peri- and Postmenopausal Women in the Aspect of Environmental Exposure to Airborne Dust Pollution
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Risk of cadmium, lead and zinc exposure from consumption of vegetables produced in areas with mining and smelting past
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Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study
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Exposure to non-continuous rotating magnetic field induces metabolic strain-specific response of Komagataeibacter xylinus
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Effect of high temperature exposure on the fatigue damage development of X10CrMoVNb9-1 steel for power plant pipes
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Investigation of morphological and electrical properties of the PMMA coating upon exposure to UV irradiation based on AFM studies
PublikacjaCelem badania było określenie wpływu promieniowania ultrafioletowego na morfologię powierzchni powłoki i na jej właściwości elektryczne. Cienka powłoka z polimetakrylanu metylu została nałożona na podłoże stalowe metodą zanurzeniową. Oceny stanu przed ekspozycją UV i w jej trakcie dokonywano przy użyciu mikroskopu sił atomowych. Na obrazach AFM zaobserwowano pojawienie się mikropęknięć. Celem zweryfikowania czy wykryte nieciągłości...
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Determination of thiocyanate (biomarkers of ETS) and other inorganic ions in human nasal discharge samples using ion chromatography
PublikacjaEnvironmental tobacco smoke (ETS) is a mixture of air and tobacco smoke containing more than 4000 chemical substances. In view of the health risks of many of these substances, studies are needed to determine biomarkers of exposure to ETS constituents in people who actively or passively are exposed to the toxic compounds. The methodologies for determining most biomarkers from saliva, urine and blood samples are known, but methods...
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Exposure of a small Arctic seabird, the little auk (Alle alle) breeding in Svalbard, to selected elements throughout the course of a year
PublikacjaThe Arctic marine ecosystem can be altered by processes of natural and anthropogenic origin. Spatio-temporal variation in species exposure to contamination is still poorly understood. Here, we studied elemental concentrations in the non-lethally collected samples from the most numerous seabird in European Arctic, the little auk (Alle alle) nesting in one breeding colony in Svalbard. This seabird spent the breeding season in the...
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Antitumor DNA-Damaging C-1748 is a New Inhibitor of Autophagy that Triggers Apoptosis in Human Pancreatic Cancer Cell Lines
PublikacjaDespite the enormous progress that has been made over the past decades in diagnosis, treatment and prevention of many types of tumors, survival rates in pancreatic cancer still remain poor. Pancreatic cancer is one of the most malignant and chemoresistant tumors and the profound mechanism supporting these phenomena is the constitutively activated prosurvival autophagy. The antitumor 1-nitroacridine derivative C-1748 belongs to...
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Long-term exposure to urban air pollution and the relationship with life expectancy in cohort of 3.5 million people in Silesia
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Bioavailability evaluation, uptake of heavy metals and potential health risks via dietary exposure in urban-industrial areas
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Stability of thin film diamond mirror for applications in interferometers under the short-time exposure on selected aggressive chemicals
PublikacjaIn presented study a thin boron-doped diamond film was proposed for application in the interferometry as a highly durable optical mirror. The unique properties of the diamond films, like high chemical stability and hardness, allow them to be used even in the chemically aggressive environment, where the commonly used silver mirrors can be susceptible to damage. The investigated nanodiamond layer was fabricated by uPE CVD method...
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Canned food as a source of bisphenol a (BPA) exposure - estimation of consumption among young women from Gdansk, Poland
PublikacjaBisfenol A (BPA) jest organicznym związkiem endokrynnie czynnym , który modyfikuje pracę hormonów prowadząc do niekorzystnych dla zdrowia skutków. BPA jest substancją stabilizującą chlorek poliwinylu- jednego z najczęściej stosowanych polimerów plastików, wykorzystywanego w produkcji powszechnie używanych produktów, w tym opakowań, plastikowych butelek, zabawek, papieru paragonowego; używany jest także w produkcji żywic epoksydowych...
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Analysis of the influence of polystyrene microplastics and their derivatives on the DNA of human colon epithelial cells HT29 with the comet assay
PublikacjaWe have been using plastic for almost a century and nowadays a lot of them circulates as pollutants in the environment and still defragmenting to micro and nanoscale. The exposition through the food chain and its precise impact on human health is still not clear. In our study, we tested real food packaging after contact with food products and real thermoinsulation and environmental samples of polystyrene in different model liquids,...
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Evaluation of excessive noise effects on hearing employing psychoacoustic dosimetry
PublikacjaResearch results regarding the noise impact on hearing applying the concept of the Psychoacoustic Noise Dosimetry (PND) are presented. The general characteristics of the PND algorithm are discussed. Additionally, the results of hearing examinations conducted in the laboratory conditions are shown. The main objective of the research was to determine the time needed for the Temporary Threshold Shift to reverse. The results were used...
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Frequently updated noise threat maps created with use of supercomputing grid
PublikacjaAn innovative supercomputing grid services devoted to noise threat evaluation were presented. The services described in this paper concern two issues, first is related to the noise mapping, while the second one focuses on assessment of the noise dose and its influence on the human hearing system. The discussed services were developed within the PL-Grid Plus Infrastructure which accumulates Polish academic supercomputer centers....
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Deterioration and Protection of Concrete Elements Embedded in Contaminated Soil: A Review
PublikacjaCoating materials are considered one of the most antique materials of human civilization; they have been used for decoration and the protection of surfaces for millennia. Concrete structures—due to their permanent exposure to different types of environments and contaminants—require the use of coatings that contribute to its preservation by reducing the corrosion of its components (steel and aggregates). This article intends to...
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DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublikacjaImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
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Long-Term Exposure of Nitrogen Oxides Air Pollution (NO2) Impact for Coronary Artery Lesion Progression—Pilot Study
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Increase of ibuprofen penetration through the skin by forming ion pairs with amino acid alkyl esters and exposure to the electromagnetic field
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Preliminary study of possible relationships between exposure to PCDD/Fs and dl-PCBs in ambient air and the length of life of people
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A GIS-based WFD oriented typology of shallow micro-tidal soft bottom using wave exposure and turbidity mapping
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P3.13-032 The Impact of Tobacco Exposure on Lung Nodules and Emphysema in a Pilot Silesian Study of Early Lung Cancer with LDCT
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Mutagenic and Carcinogenic Compounds in Food
PublikacjaFood is a major environmental human cancer risk factor. One of the reasons for this is that food products contain substances that exhibit mutagenic and carcinogenic potential which may induce the transformation of normal somatic cells into cancerous cells. These compounds occur in food as a result of microbial contaminations (mycotoxins produced by molds), are generated from natural food components upon processing (e.g. heterocyclic...
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Validated GC–MS method for determination of bisphenol a and its five analogues in dietary and nutritional supplements
PublikacjaBisphenol A (BPA) and its analogues showing structural and functional similarity to BPA are commonly applied in various industrial applications and thus are becoming ubiquitous in the environment. At the same time there is increasing scientific evidence that exposure to these chemicals may lead to adverse health effects in human and wildlife. In recent years dietary and nutritional supplements dedicated for athletes have become...
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Phototransformation of Amlodipine: Degradation Kinetics and Identification of Its Photoproducts
PublikacjaNowadays, monitoring focuses on the primary compounds and does not include degradation products formed during various biological and chemical processes. Transformation products may have the same effects to human health and the environment or sometimes they can be more toxic than the parent compound. Unfortunately, knowledge about the formation of degradation products is still limited, however, can be very important for the environmental...
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Light formed through urban morphology and different organism groups: First findings from a systematic review
PublikacjaThe prevailing implementation and usage of contemporary lighting technologies and design practices in cities have created over-illuminated built environments. Recent studies indicate that exposure to electric lighting effects formed through spatial characteristics has visual, physiological, and behavioural effects on both humans and non-humans, such as wildlife. In order to gain a better understanding of the impact that electric...
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Mocz jako źródło informacji o narażeniu zawodowym na metale = Urine as a source of information on occupational exposure to metals- a review
PublikacjaW pracy przedstawiono informacje na temat możliwości wykorzystywania próbek moczu ludzkiego jako materiału do badań analitycznych ukierunkowanych na uzyskanie informacji o narażeniu zawodowym na metale. Szczególną uwagę zwrócono na:-techniki izolacji i wzbogacania metali i ich metabolitów z próbek moczu,-techniki oznaczania metali w otrzymywanych ekstraktach,-zebranie informacji literaturowych odnośnie oznaczanych stężeń metali...
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The Mechanism of the Osteoprotective Action of a Polyphenol-Rich Aronia melanocarpa Extract during Chronic Exposure to Cadmium is Mediated by the Oxidative Defense System
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Determination of cyanide in urine and saliva samples by ion chromatography with pulsed amperometric detection
PublikacjaCommonly known as a highly toxic chemical, cyanide is also an essential reagent for many industrial processes. It naturally occurs in plant seeds as a cyanogenic glycosides. Another relatively common mode of cyanide exposure is inhalation of environmental tobacco smoke. This study concerns importance to determine cyanide ion in human biological samples. Urine and saliva samples were collected healthy volunteers exposed to tobacco...
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Recent trends in determination of neurotoxins in aquatic environmental samples
PublikacjaAnatoxins, saxitoxins, ciguatoxins, beta-N-methylamino-l-alanine and its isomers are groups of neurotoxins which have a highly specific effect on the nervous system of animals, including humans, by interfering with the transmission of nerve impulses. In order to assess the human exposure to these neurotoxins, selective, interlaboratory-validated analytical methods are being developed to facilitate obtaining reliable results on...
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IoT for healthcare applications
PublikacjaThis chapter summarizes IRACON contributions related to the application of IoT in healthcare. It consists of the following three sections. Section 8.1 presents the measurement campaigns and the related statistical analysis to obtain various channel models for wearable and implantable devices. In addition, the importance of physical human-body phantoms used for channel, Specific Absorption Rate (SAR), and Electromagnetic (EM) exposure...
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The Possible Role of PM2.5 Chronic Exposure on 5-Year Survival in Patients with Left Ventricular Dysfunction Following Coronary Artery Bypass Grafting
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Bisphenol A exposure and healing effects of Adiantum capillus-veneris L. plant extract (APE) in bisphenol A-induced reproductive toxicity in albino rats
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Supercomputing Grid-Based Services for Hearing Protection and Acoustical Urban Planning, Research and Education
PublikacjaSpecific computational environments, so-called domain grids, are developed within the PLGrid Plus project in order to prepare specialized IT solutions, i.e., dedicated software implementations and hardware (infrastructure adaptation), suited for particular research group demands. One of the PLGrid Plus domain grids, presented in this paper, is Acoustics. The article describes in detail two kinds of the acoustic domain services....
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Measures of region failure survivability for wireless mesh networks
PublikacjaWireless mesh networks (WMNs) are considered as a promising alternative to wired local, or metropolitan area networks. However, owing to their exposure to various disruptive events, including natural disasters, or human threats, many WMN network elements located close to the failure epicentre are frequently in danger of a simultaneous failure, referred to as a region failure. Therefore, network survivability, being the ability...
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Integrating Statistical and Machine‐Learning Approach for Meta‐Analysis of Bisphenol A‐Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
PublikacjaBisphenols are important environmental pollutants that are extensively studied due to different detrimental effects, while the molecular mechanisms behind these effects are less well understood. Like other environmental pollutants, bisphenols are being tested in various experimental models, creating large expression datasets found in open access storage. The meta‐analysis of such datasets is, however, very complicated for various...
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Impact of Brake Wear Particles on Eukaryotic Cell Viability and Associated Oxidative Stress Responses
PublikacjaIn this study, the cytotoxic effects of brake wear particles (≥250 nm ceramic/ceramic wear particles (CCWPs) and ≤100 nm ceramic/steel wear particles (CSWPs)) and 100 nm iron (III) oxide ultrafine particles (IOUFPs) on human lung carcinoma (A549) and Chinese hamster ovary (CHO) cells were investigated. Cell viability was determined using the MTT and Calcein AM methods. Oxidative stress was assessed by measuring reactive oxygen...
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Levels of hemoglobin and lipid peroxidation metabolites in blood, catalase activity in erythrocytes and peak expiratory flow rate in subjects with passive exposure to tobacco smoke
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The relationship between children's non-nutrient exposure to cadmium, lead and zinc and the location of recreational areas - Based on the Upper Silesia region case (Poland)
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