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Wyniki wyszukiwania dla: HUMAN HAIR
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Can cornelian cherry mask bitter taste of probiotic chocolate? Human TAS2R receptors and a sensory study with comprehensive characterisation of new functional product
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Replicating DNA by cell factories: roles of central carbon metabolism and transcription in the control of DNA replication in microbes, and implications for understanding this process in human cells
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The effect of oxidized cholesterol on barrier functions and IL-10 mRNA expression in human intestinal epithelium co-cultured with dendritic cells in the transwell system
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Pro-apoptotic action of protein-carbohydrate fraction isolated from coelomic fluid of the earthworm Dendrobaena veneta against human colon adenocarcinoma cells
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Human Induced Pluripotent Stem Cell-Derived Microvesicles Transmit RNAs and Proteins to Recipient Mature Heart Cells Modulating Cell Fate and Behavior
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When Biobanks Meet Religion: Association Between Religiosity and Attitudes of Polish Medical Students Toward Biobanking of Human Biological Material for Research Purposes
PublikacjaWhile biobanking is expanding globally, the empirical evidence concerning the impact of religion on future healthcare professionals’ awareness and willingness to donate biospecimens for biobank research is lacking. To understand how medicalstudents’ religious beliefs can fuel their questions regarding how biospecimens would be stored, cared for, and used, we conducted a survey among 1500 medical students at Poznań University...
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Highly Specific Substrates of Proteinase 3 Containing 3-(2-Benzoxazol-5-yl)-l-alanine and Their Application for Detection of This Enzyme in Human Serum
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Bardoxolone Methyl Displays Detrimental Effects on Endothelial Bioenergetics, Suppresses Endothelial ET-1 Release, and Increases Endothelial Permeability in Human Microvascular Endothelium
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Imidazoacridinone derivative C-1311 (SymadexTM) induces apoptosis, mitotic catastrophe or senescence in human colon carcinoma HCT116 cells depending on p53 status
PublikacjaPrzeprowadziliśmy badania zmierzające do wyjaśnienia odpowiedzi komórek ludzkiego raka jelita grubego HCT116 traktowanych C-1311 w zależności od statusu białka p53. Wykazaliśmy, że pochodna imidazoakrydonu C-1311 w stężeniach biologicznie istotnych indukuje przejściowy blok w fazie G2M komórek HCT116 p53-/- oraz blok w fazie G1 i G2M komórek HCT116 p53+/+. W komórkach z niefunkcjonalnym białkiem p53 imidazoakrydon indukował katastrofę...
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Bio and slide biobearings, their lubrication by non-newtonian fluids and application in non-conventional systems. Vol. 2, The theory of human joint unsteady lubrication.
PublikacjaW monografii przedstawiono zasady niestacjonarnego smarowania stawów człowieka o odkształcalnych chrząstkach i powierzchniach kostnych w polach indukcji magnetycznej. W opisie stochastycznym uwzględnione zostały nienewtonowskie, lepkosprężyste właściwości cieczy synowialnych jako czynnika smarującego. Monografia prezentuje rozkłady wartości ciśnienia i nośności stawów człowieka w warunkach niestacjonarnego smarowania dla drgań...
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Application of analytical procedure based on accelerated solvent extraction and ion chromatography technique for determination of thiocyanate and other inorganic ions in human placenta samples
PublikacjaExposure of a pregnant woman during pregnancy is a special case of exposure to toxic substances. Samples of placenta collected for the studies had been prepared with the technique of accelerated solvent extraction and later analyzed for the presence of thiocyanate ion and other inorganic ions, with the use of the technique of ion chromatography. The concentration of thiocyanate ion in placenta samples collected from active smokers...
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Modern approach for determination of lactulose, mannitol and sucrose in human urine using HPLC-MS/MS for the studies of intestinal and upper digestive tract permeability
PublikacjaA new analytical procedure was described for the simultaneous determination of lactulose, mannitol and sucrose in urine, in which HILIC chromatography and tandem mass spectrometry detection are used. Sugars are orally administered for the estimation of intestinal permeability in children digestive tract. Samples were purified by dispersive solid phase extraction (d-SPE) using Amberlite MB150 resin. Raffinose was selected as an...
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Modification of gradient HPLC method for determination of small molecules' affinity to human serum albumin under column safety conditions: Robustness and chemometrics study
PublikacjaIn the early stages of drug discovery, beyond the biological activity screening, determining the physicochemical properties that affect the distribution of molecules in the human body is an essential step. Plasma protein binding (PPB) is one of the most important investigated endpoints. Nevertheless, the methodology for measuring %PPB is significantly less popular and standardized than other physicochemical properties, like lipophilicity....
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Discriminating macromolecular interactions based on an impedimetric fingerprint supported by multivariate data analysis for rapid and label-free Escherichia coli recognition in human urine
PublikacjaThis manuscript presents a novel approach to address the challenges of electrode fouling and highly complex electrode nanoarchitecture, which are primary concerns for biosensors operating in real environments. The proposed approach utilizes multiparametric impedance discriminant analysis (MIDA) to obtain a fingerprint of the macromolecular interactions on flat glassy carbon surfaces, achieved through self-organized, drop-cast,...
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Acute Effects of Electronic and Tobacco Cigarette Smoking on Sympathetic Nerve Activity and Blood Pressure in Humans
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An independent relationship between muscle sympathetic nerve activity and pulse wave velocity in normal humans
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Journey towards light – evolutionary adaptations of humans, flora and fauna. Guidelines for safe and healthy illumination
PublikacjaThe paper examines using relatively recent discoveries on how evolution has embedded within all living organisms a natural sensitivity towards their native environment, in particular luminance levels and specific wavelengths of light. The studies conducted so far indicate that lighting installations that are visible after dark impact on humans, flora and fauna and influence our evolutionary dispositions, possibly with negative...
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Remote Monitoring of Environmental Pollutants
PublikacjaAtmospheric air quality is one of the key factors influencing human health. Air quality evaluation is not an easy task as the atmosphere is a complex system subjected to continuous changes in time. Observed progress in the development of measurement devices and technologies is fundamental for acquisition of more reliable information about condition and quality of atmospheric air. Unfortunately, this process leads to an increase...
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Effect of silver/copper and copper oxide nanoparticle powder on growth of Gram-negative and Gram-positive bacteria and their toxicity against the normal human dermal fibroblasts
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Expression of genes involved in neurogenesis, and neuronal precursor cell proliferation and development: Novel pathways of human ovarian granulosa cell differentiation and transdifferentiation capability in�vitro
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Genes responsible for proliferation, differentiation, and junction adhesion are significantly up-regulated in human ovarian granulosa cells during a long-term primary in vitro culture
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Destabilization of β‐Hemocyanin from Helix pomatia in Presence of Choline Amino Acids Results in Improved Cell Specificity and Cytotoxicity against Human Breast Cancer
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Protective effect of Aronia melanocarpa polyphenols against cadmium-induced disorders in bone metabolism: A study in a rat model of lifetime human exposure to this heavy metal
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Drug affinity to human serum albumin prediction by retention of cetyltrimethylammonium bromide pseudostationary phase in micellar electrokinetic chromatography and chemically advanced template search descriptors
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Antitumor potential of new low molecular weight antioxidative preparations from the white rot fungus Cerrena unicolor against human colon cancer cells
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Induction of Secreted Human Immunodeficiency Virus Type 1 (HIV-1) Resistance Factors in CD4-Positive T Lymphocytes by Attenuated HIV-1 Infection
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Środowiskowy dym tytoniowy - skład, oddziaływanie na organizm, problemy analityczne = Environmental tobacco smoke - chemical constituents, impact on human health, analytical problems
PublikacjaPalenie tytoniu jest przyczyną znacznego zanieczyszczenia powietrza wewnętrznego różnego typu pomieszczeń. Wiele związków chemicznych wydzielających się wraz z głównym i bocznym strumieniem dymu papierosowego wykazuje charakter rakotwórczy, a także wywołuje skutki toksyczne odległe w czasie. Różny stopień narażenia na szkodliwe składniki środowiskowego dymu tytoniowego obserwuje się zarówno u aktywnych, jak i biernych palaczy....
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Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublikacjaPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
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Viscoelastic lubrication of human hip joint for impulsive motion after injury. Lepkosprężyste smarowanie stawu biodrowego człowieka dla impulsywnego ruchu po urazie.
PublikacjaW pracy rozpatruje się urazy wywołujące zmniejszenie lub zwiększenie wysokości i zmiany kształtu szczeliny stawu, które to zmiany po pewnym określonym czasie po doznanym urazie mogą zanikać. W konsekwencji takich urazów i to w bardzo krótkim czasie rzędu mikrosekund następują bardzo istotne zmiany parametrów smarowania. Mamy tu na uwadze zmiany rozkładów wartości ciśnienia i sił nośnych. Takie zmiany warunków smarowania nieustalonego...
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Long Short-Term Memory (LSTM) neural networks in predicting fair price level in the road construction industry
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Upscaling biomass production of rosmarinic acid-rich hairy root cultures of Agastache rugosa (Fisch. & C.A.Mey.) Kuntze
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Production of tropane alkaloids in Hyoscyamus niger (black henbane) hairy roots grown in bubble-column and spray bioreactors
PublikacjaHairy root cultures of Hyoscyamus niger were cultivated in shake-flasks, a bubble-column bioreactor and a hybrid bubble-column/spray bioreactor and evaluated for alkaloid production.
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The Impact Of The Selected Parameters Of Fdm Manufacturing Technology On Tribological Performance Of Abs–Steel Pair Under Dry Friction
PublikacjaThe paper presents the result of tribological test of ABS and steel samples sliding under dry friction. Polymeric samples were manufactured of ABS material using FDM technology. Testing was carried out in unidirectional sliding in a ring-on-flat contact in a PT-3 tribometer. The scope of tested parameters included volumetric and mass wear, the friction coefficient, and polymeric specimen temperature. Polymeric specimens used in...
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Monitoring of Selected CBRN Threats in the Air in Industrial Areas with the Use of Unmanned Aerial Vehicles
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Maintenance Interval Adjustment Based on the Experience, Case Study of Marine Air Compressor System
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Experimental determination of critical conditions for hydrogen-air detonation propagation in partially confined geometry
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approximation of photonic crystal fibres with large air holes by the step index fibre model
PublikacjaAn equivalent step index fibre with a silica core and air cladding is used to model photonic crystal fibres with large air holes. We model this fibre for linear polarisation (we focus on the lowest few transverse modes of the electromagnetic field). The equivalent step index radius is obtained by equating the lowest two eigenvalues of the model to those calculated numerically for the photonic crystal fibres. The step index parameters...
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Numerical modeling of cross-flow heat exchanger for air-conditioning purposes in preliminary study.
PublikacjaPraca przedstawia wyniki obliczeń numerycznych krzyżowego płytowo-rurowego wymiennika ciepła przeznaczonego do celów klimatyzacyjnych w początkowym etapie jego projektowania.
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Effect of native air-formed oxidation on the corrosion behavior of AA 7075 aluminum alloys
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Air–sea exchange of mercury vapour over the Gulf of Gdańsk and southern Baltic Sea
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Application of TiO2 Supported on Nickel Foam for Limitation of NOx in the Air via Photocatalytic Processes
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Air journal bearing utilizing near-field acoustic levitation: stationary shaft case
PublikacjaResults of a study to examine a unique idea of self-levitating journal bearing are presented in this paper. the idea represents a radical departure from the current bearing technology. it utilisesacoustic levitation, which relies on the sound energy radiated by an object supporting a load. acoustic levitation has been demonstrated to support loads of up to 10 kg. in order to support a load theacoustic wave emitted by the radiating...
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Analysis of inductive power transfer systems for variable air gap and voltage supply frequency
PublikacjaThe paper describes an IPT system, by which electrical energy may be transmitted through a large air gap between coils without electrical connection. It presents theoretical and simulation analysis of IPT, which allows for supplying a receiver in the conditions of slow, in relation to the dynamics of power supply, changes in dimension of the air gap. The influence of frequency characteristics of the system on the possible selection...
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Low temperature removal of SO2 traces from air by MgO-loaded porous carbons
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Health impacts of indoor air pollution from household solid fuel on children and women
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Chitosan/phospholipid coated polyethylene terephthalate (PET) polymer surfaces activated by air plasma
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The role of tricalcium aluminate and gypsum dehydration level in cement for effective air entrainment of concrete
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Air temperature trends at Mount Śnieżka (Polish Sudetes) and solar activity, 1881–2012
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Sound velocity and parameter of nonlinearity of a ternary mixture consisting of water, vapour and dry air
PublikacjaRozpatruje się własności akustyczne mieszanki trójskładnikowej zawierającej wodę, parę wodną i suche powietrze. Dokładne obliczenia pozwoliły na wyprowadzenie prędkości dźwięku i parametru nieliniowości jako funkcji koncentracji pary wodnej i powietrza przy zadanych warunkach równowagowych. Rozpatrywane są dwa typy mieszanin. Przedstawiono wzory ogólne oraz symulacje numeryczne.
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Exchange of radiation in high temperature air combustion furnaces by application of the transfer configuration factors
PublikacjaW artykule przedstawiono metodę obliczeń pasmowej radiacyjnej wymiany ciepła w układzie otwartym z gazem iztermicznym za pomocą uogólnionych współczynników konfiguracji. Metoda może być użyta do obliczeń wymiany ciepła w piecach z technologią High Temperature Air Combustion gdzie występuje prawie jednorodna temperatura. Podano przykład obliczeniowy.