Filtry
wszystkich: 1244
wybranych: 790
Wyniki wyszukiwania dla: metabolic syndrome
-
Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions
Publikacja -
Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc
Publikacja -
Retained features of embryonic metabolism in the adult MRL mouse
PublikacjaThe MRL mouse is an inbred laboratory strain that was derived by selective breeding in 1960 from the rapidly growing LG/J (Large) strain. MRL mice grow to nearly twice the size of other commonly used mouse strains, display uncommonly robust healing and regeneration properties, and express later onset autoimmune traits similar to Systemic Lupus Erythematosis. The regeneration trait (heal) in the MRL mouse maps to 14-20 quantitative...
-
Metabolomic Signature of Early Vascular Aging (EVA) in Hypertension
Publikacja -
Vascular Aging and Damage in Patients with Iron Metabolism Disorders
Publikacja -
Parametric imaging in dynamic glucose metabolism studies in brain
PublikacjaArtykuł analizuje badania dynamiczne 18FDG-PET, które służą do estymacji metabolizmu glukozy w mózgu. Zbadano w nim wpływ zakłóceń na wyznaczanie interesującego nas parametru LCMRGlc.
-
Proteomic and Metabolomic Changes in Psoriasis Preclinical and Clinical Aspects
PublikacjaSkin diseases such as psoriasis (Ps) and psoriatic arthritis (PsA) are immune-mediated inflammatory diseases. Overlap of autoinflammatory and autoimmune conditions hinders diagnoses and identifying personalized patient treatments due to different psoriasis subtypes and the lack of verified biomarkers. Recently, proteomics and metabolomics have been intensively investigated in a broad range of skin diseases with the main purpose...
-
Conservative treatment of Herlyn-Werner-Wunderlich syndrome: Analysis and long-term follow-up of 51 cases
Publikacja -
Three-Dimensional Echocardiography and Global Longitudinal Strain in Follow-Up After Multisystem Inflammatory Syndrome in Children
Publikacja -
The development of speech in early childhood in children from twin pregnancies with twin-twin transfusion syndrome (TTTS)
Publikacja -
Social networks as a context for small business? A new look at an enterprise in the context of a smallness and newness liability syndrome
PublikacjaIn this paper we aim to propose and outline key ingredients to a small enterprise success, emerging from the social capital of small business owner-managers and their business networks. We employ resource based view of an organization as well as an embeddedness perspective along with new approach transaction costs to outline the pillars of an advantage of a small business entity. The analysis of survey data leads us to conclusion,...
-
Adipokine and cytokine levels in non-functioning adrenal incidentalomas (NFAI)
PublikacjaDue to the fact that overweight or obesity is accompanied by hormonally active adrenal tumors: Cushing Syndrome-(CS) and Subclinical Cushing Syndrome (SCS), it is of high interest the correlation between different adipokines and cytokines secreted by adipose tissue, with metabolic disorders and hormonal activity in this group. Even in non-functioning adrenal incidentalomas (NFAI) elevated risk for cardiovascular disease and metabolic...
-
Role of adenylate kinase 4 as a new metabolic regulator of pulmonary artery smooth muscle cells under hypoxia
Publikacja -
Metabolic response of cornflower (Centaurea cyanus L.) exposed to tribenuron-methyl: one of the active substances of sulfonylurea herbicides
Publikacja -
30‐Day morbidity and mortality of bariatric metabolic surgery in adolescence during the COVID‐19 pandemic – The GENEVA study
Publikacja -
The metabolic profiles of pterin compounds as potential biomarkers of bladder cancer—Integration of analytical-based approach with biostatistical methodology
Publikacja -
Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
PublikacjaElectrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...
-
Chiral Pyrazolo[4,3-e][1,2,4]triazine Sulfonamides—Their Biological Activity, Lipophilicity, Protein Affinity, and Metabolic Transformations
PublikacjaReferring to our previous laboratory results related to the tyrosinase and urease inhibition by pyrazolo[4,3-e][1,2,4]triazine sulfonamides, we examined here in silico the mechanism of action at the molecular level of the investigated pyrazolotriazine sulfonamides by the molecular docking method. The studied compounds being evaluated for their cytotoxic effect against cancer cell lines (MCF-7, K-562) and for recombinant Abl and...
-
Oxide Layers Fabricated by Spray Pyrolysis on Metallic Surfaces
Publikacjaw pracy przedstawiono wyniki badań nad opracowaniem optymalnych warunków przygotowania warstwy stabilizowanego itrem cyrkonu jako prekursora na stali 316L jako podłoża za pomocą pirolizy aerozolowej.
-
Modeling for Detection of Degraded Zones in Metallic and Composite Structures
PublikacjaW pracy przedstawiono przegląd metod modelowania uszkodzeń w postaci pęknięć i delaminacji wystepujących w elementach konstrukcyjnych
-
Experiments on damage development in metallic plates subjected to explosions
PublikacjaW pracy przedstawiono badania eksperymentalne rozwoju zniszczenia płyt metalowych pod wpływem eksplozji. Zaprezentowano opis badan statycznych i dynamicznych na płytach oraz opis badan jednoosiowych. Dla założonego modelu równania konstytutywnego przedstawiono sposób identyfikacji parametrów materiałowych.
-
Tunable Waveguide Filter with Bow-Tie Metallic Posts.
PublikacjaBadanie i synteza filtru falowodowego zawiewrającego metalowe rezonatory motylkowe (Bow-Tie). Wykorzystano zmodyfikowaną procedurę iteracyjną i metodę dopasowania rodzajów w celu rozwiązania problemu brzegowego na pojedynczej sekcji filtru i określenie pola rozproszonego od rezonatora motylkowego. Obrót i przemieszczenie opisywane struktury w złączu falowodowym umożliwia zmianę odpowiedzi częstotliwościowych układu. Efekt rotacji...
-
Machining of the flat surfaces with abrasive-metallic lapping tools.
PublikacjaPrzedstawiono konstrukcje narzędzi ścierno-metalowych do obróbki powierzchni płaskich na docierarkach jednotarczowych. Przeprowadzono badania wydajności i jakości powierzchni elementów ceramicznych o małych gabarytach.
-
Selective oxidation of metallic single-walled carbon nanotubes
Publikacja -
Conducting polymer films for biodegradable metallic cardiovascular stents
PublikacjaIn recent years, there is increasing interest to create biodegradable metallic cardiovascular stents instead of using their permanent form. The most interesting materials for this purpose are iron and its alloys. However, in order to use it in clinical application, their degradation rate and biological performance need to be optimized. One promising solution is coating the metal with conducting polymer films. In this work, short...
-
Transcriptomic Profile of Genes Encoding Proteins Involved in Pathogenesis of Sjögren’s Syndrome Related Xerostomia—Molecular and Clinical Trial
Publikacja -
Nephrotic syndrome unfavorable course correlates with downregulation of podocyte vascular endothelial growth factor receptor (VEGFR)-2
Publikacja -
SYNDROM CHOREGO BUDYNKU – PROBLEMY PROJEKTOWE NA PRZYKŁADACH Z WOJEWÓDZTWA POMORSKIEGO
PublikacjaPodczas przebudowy obiektów budowlanych, zwłaszcza pomieszczeń ze stanowiskami pracy, projektant staje przed koniecznością rozwiązania wielu różnorodnych problemów projektowo-wykonawczych. Jednym z nich jest możliwość degeneracji tkanki budowlanej – zjawiska prowadzącego do powstawania wśród użytkowników budynku zespołu przypadłości opisywanych w literaturze jako syndrom chorego budynku. Nieprawidłowo funkcjonujący budynek jest...
-
Peroxidative metabolism of fatty acids in the course of tick-borne encephalitis
Publikacja -
Updates on Metabolism in Lactic Acid Bacteria in Light of “Omic” Technologies
Publikacja -
The association between irisin and muscle metabolism in different thyroid disorders
Publikacja -
Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases
Publikacja -
New Chalcones Derivatives With Potent Antitumor Activity And Their Metabolism In Vitro
PublikacjaChalcone derivatives exhibit a broad range of biological activities, with antioxidant and cytotoxic properties among the most studied. Despite numerous reports on chalcones as cytotoxic, and potentially anticancer agents, very little is know on their actual mechanism of activity. Generally, chalcones are considered as antimitotic agents, which interfere with tubulin assembly.We have recently developed a new class of chalcones with...
-
Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism
Publikacja -
Metabolomic and antioxidant properties of different varieties and origins of Dragon fruit
PublikacjaDragon fruit has appealed much concern from consumers as a novelty fruit with potent nutritional and medicinal benefits. Dragon fruit quality warrants comprehensive evaluation, based on the contents of pigments and health- promoting natural compounds in different varieties. This study was aimed to evaluate the differences among dragon fruit varieties extracted with methanol–water (CD3OD-D2O) and methanol (CD3OD) by proton nuclear magnetic...
-
Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
PublikacjaPurpose: Surgical resection of hepatocellular carcinoma can be associated with recurrence resulting from the degeneration of residual volume of the liver. The objective was to assess the possibility of using a biocompatible nanofilm, made of a colloid of diamond nanoparticles (nfND), to fill the side after tumour resection and optimize its contact with proliferating liver cells, minimizing their cancerous transformation. Methods:...
-
Folate/homocysteine metabolism and lung cancer risk among smokers
PublikacjaBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
-
Cross-linking of sodium caseinate-structured emulsion with transglutaminase alters postprandial metabolic and appetite responses in healthy young individuals
PublikacjaThe physico-chemical and interfacial properties of fat emulsions influence lipid digestion and may affect postprandial responses. The aim of the present study was to determine the effects of the modification of the interfacial layer of a fat emulsion by cross-linking on postprandial metabolic and appetite responses. A total of fifteen healthy individuals (26·5 (sem 6·9) years and BMI 21·9 (sem 2·0) kg/m2) participated in a cross-over...
-
“Positive Regulation of RNA Metabolic Process” Ontology Group Highly Regulated in Porcine Oocytes Matured In Vitro: A Microarray Approach
Publikacja -
Metabolic Evaluation of Urine from Patients Diagnosed with High Grade (HG) Bladder Cancer by SPME-LC-MS Method
Publikacja -
Phytotoxic Activity of Metabolites Isolated from Rutstroemia sp.n., the Causal Agent of Bleach Blonde Syndrome on Cheatgrass (Bromus tectorum)
Publikacja -
Euthyroid sick syndrome as a prognostic indicator of COVID-19 pulmonary involvement, associated with poorer disease prognosis and increased mortality
Publikacja -
Kinetics studies of recrystallization process of metallic catalysts for ammonia synthesis
Publikacja -
Hybrid quantum-classical approach for atomistic simulation of metallic systems
PublikacjaThe learn-on-the-fly (LOTF) method [G. Csanyi et al., Phys. Rev. Lett. 93, 175503 (2004)] serves to seamlessly embed quantum-mechanical computations within a molecular-dynamics framework by continual local retuning of the potential's parameters so that it reproduces the quantum-mechanical forces. In its current formulation, it is suitable for systems where the interaction is short-ranged, such as covalently bonded semiconductors....
-
Ductile fracture prediction in thin metallic plates subjected to explosions
PublikacjaPraca dotyczy modelowania zniszczenia ciągłego. Zaprezentowano wyniki eksperymentów przeprowadzonych na płytach metalowych poddanych eksplozjom oraz wyniki jednoosiowych prób laboratoryjnych. Opisano przyjęty model prawa konstytutywnego oraz kryteriów zniszczenia. Przedstawiono identyfikację parametrów materiałowych dla przyjętego modelu. Zaprezentowano model numeryczny oraz wyniki symulacji które następnie porównano z wynikami...
-
Comparison of experimental and numerical results on metallic plates subjected to explosions
PublikacjaA comparative study of dynamic response including damage and rupture processes of thin metallic plates subjected to shockwave impulses - explosions is presented. The results of the finite element numerical analysis are related to experiments. Due to high strain rate during explosions the elasto-viscoplastic Chaboches constitutive law including damage effects has been applied. For the assumed model proper material parameters identification...
-
On fatigue safety of metallic elements under static and dynamic loads.
PublikacjaGłównym celem monografii było wyznaczenie współczynników bezpieczeństwa i kryteriów projektowych z uwzględnieniem wpływu obciążeń statycznych oraz naprężeń średnich i resztowych na wytrzymałość zmęczeniową przy obciążeniach okresowych i/lub stochastycznych. Uzyskano to za pomocą wyznaczonych naprężeń równoważnych i równania Soderberga. Otrzymano kryteria w postaci zamkniętej i zgodnej z wzorem Milesa na trwałość zmęczeniową oraz...
-
The allergic and irritating reactions to metallic implants with trauma - orthopaedic patients
PublikacjaThe article presents the analysis of clinical operation complications after the treatment of long bones by mean of ostheosynthesis with the use of metal implants and endoprothesoplastic of hip joints.
-
Formation of Porous Structure of the Metallic Materials Used on Bone Implants
PublikacjaResearch on improvement of structure and fabrication methods of the bone implants are carried out for many years. Research are aimed to shape the structures, that will have a Young's modulus value similar to the value of the human bones Young's modulus. Depending on theporosity, Young's moduli can even be tailored to match the modulus of bone closer than solid metals can, thus reducing the problems associated with stress shielding...
-
Bandwidth Dependence of the Propagation Channel in Circular Metallic BAN Environments
PublikacjaIn this paper, the bandwidth dependence of the propagation channel for Body Area Networks (BANs) in circular metallic environments is addressed and models are proposed to evaluate the appropriate short-term fading margins that should be considered as a function of the system bandwidth. The deployment of BANs in metallic indoor environments, such as ships, factories, warehouses and other similar environments, involves additional...