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Wyniki wyszukiwania dla: REGENERATION, P21
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Sequence variants of p21 gene of the MRL/MpJ mouse: a possible association with the deficit of p21 protein and regenerative phenotype.
PublikacjaThe MRL/MpJ mouse is known for its enhanced regeneration abilities that manifested themselves by scarless ear-hole wound closure. The deficit of p21 found in the MRL is associated with the regenerative capacity as the p21 gene knockout in a mouse strain unrelated to the MRL mouse results in an ear-hole closure effect, similar to that observed in the MRL mouse. Cdkn1a gene encodes p21 protein, a cyclin-dependent kinase inhibitor,...
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Study on Microstructural Characterization, Mechanical Properties and Residual Stress of GTAW Dissimilar Joints of P91 and P22 Steels
PublikacjaThis article deals with the dissimilar joining of two different grade Cr-Mo steel (2.25Cr-1Mo: P22 and modified 9Cr-1Mo: P91) for power plant application. The dissimilar butt-welded joint was produced for conventional V groove design by using the gas tungsten arc welding (GTAW) process with the application of an ERNiCrMo-3 Ni-based super alloy filler. A microstructure characterization was performed to measure the inhomogeneity...
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Ograniczone (p1, p2,...,pk) kolorowanie wierzchołków grafów.
PublikacjaProblem ograniczonego (p1,...,pk) kolorowania grafów polega na poszukiwaniu odpowiedzi na pytanie, czy istnieje takie pokolorowanie wierzchołków grafu , że krotności użycia poszczególnych barw są równe ustalonym progom p1,...,pk. W ogólnym przypadku problem ten, jako uogólnienie klasycznego kolorowania grafów pozostaje NP-zupełnym. W pracy przedstawiamy wyniki dotyczące ograniczonego kolorowania split grafów, kografów oraz...
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Insight into heart regeneration
PublikacjaThe mammalian heart is thought to be incapable of regeneration because of the limited ability of cardiomyocytes. to proliferate. However, it has been recently shown that the neonatal murine heart is able to restore its normal function after coronary artery ligation or even partial resection. Unfortunately, this feature is lost in a few days after birth, although lower vertebrates as zebrafish or newt, retain this ability until adulthood. Therefore,...
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The role of epigenetics in regeneration
PublikacjaComplex changes in chromatin structure and at the transcriptional level occur from the creation of a single parental gamete throughout fertilization, embryo development and the life of an adult organism. Epigenetic changes, such as methylation and hydroxymethylation of DNA or histone methylation and acetylation, are an important part of these processes. Epigenetic regulation has an essential influence on gene expression level. DNA...
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Discovery of small-molecule regenerative drugs using a model of complex tissue injury in mice. Transcriptomic responses of neurodevelopmental genes during pharmacologically induced regeneration
PublikacjaDespite significant development in regenerative medicine, there is a deficit of effective therapies for wound healing and tissue regeneration. Research performed using animal wound models allows for a better understanding of this complex process, searching for compounds with pro-regenerative properties, and assessing their efficacy and safety. Unfortunately, the lack of adequate preclinical models proves to be an issue as no animal...
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Polydopamine Biomaterials for Skin Regeneration
PublikacjaDesigning biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic cellular interactions. Polydopamine (PDA) is a natural bioadhesive and bioactive polymer that endows high chemical versatility, making it an exciting candidate for a wide range of...
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Identity and authenticity in urban regeneration
PublikacjaArtykuł dotyczy zagadnienia relacji pomiędzy kwestiami ochrony autentyzmu a budowy jego tożsamości w programach rewitalizacji urbanistycznej.
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Urban Waterfront Regeneration: Origins of the Issue
PublikacjaThis paper deals with the origins of the issue of urban waterfront regeneration. The process of city-water interface was described with references to the three generations of port structures.
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Challenges of Cogeneration
PublikacjaPrzedstawiono problemy skojarzonego wytwarzania ciepła i energii elektrycznej w Polsce. Omówiono układy technologiczne i problemy sprawności wytwarzania skojarzonego. podano przykłady problemów, które powinny być rozwiązane w nowych warunkach ekonomicznych zarówno w dziedzinie optymalizacji ekonomicznej jak i technologicznej.
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From Regenerative Buildings to Regenerative Urban Projects: Design frameworks to scale up within the area of regenerative practice
PublikacjaIn this chapter, a discussion will be presented of design frameworks and assessment tools that are useful for boosting the scale jumping of regenerative design practices and the paradigm shift. Our main objectives will be to identify existing design and assessment frameworks, to describe the way they work and how they can contribute to scale-jumping regenerative design, as well as to identify shortcomings and opportunities. We...
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Sources of investment risk in urban regeneration projects
PublikacjaThe scope of the article includes multidimensional risk analysis of urban regeneration projects, whose base is to identify areas of its occurrence. Authors thoroughly analyze the sources of potential threats and attempts to answer the question, what is their contribution into overall urban regeneration’ investment risk. The target concept will be used to assess the level of investment risk at the stage of initiation, preparation...
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Urban development and regeneration in Poland - contemporary issues
PublikacjaArtykuł obejmuje skrótowe omówienie współczesnych procesów rozwoju i rewitalizacji miast w Polsce. Zaprezentowano w nim zarówno procesy planowe jak i zachodzące spontanicznie, a także typologie obszarów poddawanym współczesnym procesom przekształceń
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Places of worship, spiritual healing and urban regeneration
PublikacjaMany researchers demonstrated that it is possible to help people achieve mental and physical regeneration with proper architecture, urban and landscape planning. The term therapeutic landscapes could also be applied to places of worship, where people gather for spiritual healing and renewal. Public space that they offer is inclusively open to all. Addition- ally, they serve to reinvigorate the places where they are located. Shrines...
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Definition of urban regeneration projects in Russian cities
PublikacjaUrban regeneration is extremely important process for Russian cities, which faced to the challenges of post-industrial economy. In an attempt, to explain needs of urban regeneration in Russian megacities author analyzed the social and economic trends and some historic features of Russian cities development. The article identified the key areas for regeneration such as the regeneration of historic core, the regeneration of the urban...
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Market Regeneration in Line with Sustainable Urban Development
PublikacjaThis article presents the study of the optimal design solutions for regeneration of marketplaces. It examines the design variants for the revitalisation of the marketplace, in particular, investment in their modernisation in order to find the most optimal model for transforming these public spaces to have a significant impact on the city’s development. The research is a comparative analysis of the implementation of regeneration...
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Evaluation of Antifungal Properties of Titania P25
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Dye decomposition on P25 with enhanced adsorptivity
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Intelligent artificial joint and regeneration problems in articular joints
PublikacjaPraca przedstawia zasady działania inteligentnych sztucznych stawów biodrowych człowieka oraz problemy regeneracji chrząstek stawowych w stawach naturalnych człowieka. Postuluje się wagę podjętych badań w powyższym problemie.Zwrócono uwagę na problemy związane ze sterowaniem własności sztucznych stawów biodrowych oraz z identyfikacją impulsów przekazywanych naturalnym połączeniom stawowym człowieka.
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Regeneration of marine engine valves using laser surfacing
PublikacjaThis article presents an analysis of the applicability of laser surfacing of the exhaust valve face of a marine diesel engine using cobalt-based powder. After preparation by machining, the selected valves were subjected to laser surfacing using a high-power ROFIN DL020 laser. The EuTroLoy 16012 powder was used in the surfacing process. One of the valves was cut and subjected to metallographic examination and hardness measurements,...
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Public Lighting in a Context of Regeneration Processes in Polish Cities
PublikacjaThe purpose of this paper is to reflect on the role of electric lighting design in urban regeneration processes. The landscape of the modern city is the result of an accumulation of the various physical, economic, social and cultural layers over the centuries. Urban lighting may be described as one of the physical layers which due recent developments in the technology of efficient light sources overcomes a major evolution. With...
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ANALYSIS OF THE INCREASE OF CONSTRUCTION COSTS IN URBAN REGENERATION PROJECTS
PublikacjaThe subject of this paper is the analysis and evaluation of the reasons for construction costs increases in urban regeneration projects. The analysis considers major refurbishments of real estates’, as well as heavy repair and modernization of the road system. For the period mentioned, the costs from works and expenditure schedules were compared with the costs of additional works, which shows the percentage cost increase in relation...
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Comparative Analysis of Contemporary Regeneration of Waterfronts in Port Cities
PublikacjaThe paper includes comparative analysis of the selected waterfront case studies in cities around Europe and North America.
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Polylysine for Skin Regeneration: A Review of Recent Advances and Perspectives
PublikacjaThere have been several attempts to find promising biomaterials for skin regeneration, among which polylysine (a homopolypeptide) has shown benefits in the regeneration and treatment of skin disorders. This class of biomaterials has shown exceptional abilities due to their macromolecular structure. Polylysine-based biomaterials can not only be used as tissue engineering scaffolds for skin regeneration, but also as drug carriers...
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A Review on Deactivation and Regeneration of Catalysts for Dimethyl Ether Synthesis
Publikacjahe deactivation of catalysts and their regeneration are two very important challenges that need to be addressed for many industrial processes. The most quoted reasons for the deterioration of dimethyl ether synthesis (DME) concern the sintering and the hydrothermal leaching of copper particles, their migration to acid sites, the partial formation of copper and zinc hydroxycarbonates, the formation of carbon deposits, and surface...
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Next Generation Digital
PublikacjaThe paper outlines the major objectives of the MENAID research project, eimed at novel architectures of digital documents. Such documents will enable reduction of information overflow and strain, a major threat to the growth of a digital society. They will be forward compatible, technology neutral and lightweight, allowing workers of network organizations to use personal devices of any type.
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Optimization of the geometry of the crankshaft for an internal combustion engine with heat regeneration
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Groundwater quality regeneration in the discharge zone of the Gdansk aquifer system
PublikacjaEksploatacja wód podziemnych w rejonie Gdańska prowadzona jest głównie w strefie drenażu wód na nizinach nadmorskich. Wieloletni, intensywny pobór spowodował niekorzystne zmiany w ich jakości, są one głównie związane z zasoleniem wód podziemnych intruzjami wód morskich. Sytuacja ta dotyczy zwłaszcza pietra czwartorzędowego. Spadek wilekości eksploatacji, który obserwuje się od lat 90. prowadzi poprawy jakości wód podziemnych, a...
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Urban regeneration vs. urban sprawl - is the ''compact city'' possible?
PublikacjaArtykuł dotyczy zagadnień zrównoważonego rozwoju miast i konceptu ''miasta kompaktowego''. Poruszone zostały zagadnienia zasad urbanistycznych współczesnego rozwoju miasta oraz problem rewitalizacji urbanistycznej.
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Separation of effluents from regeneration of a cation exchanger by membrane distillation
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Street Art and Urban Regeneration. Case Study Gdansk and Rome.
PublikacjaStreet art plays an important role in urban planning as a transforming engine to regenerate the public spaces and in the processes of participation. The article analyzes two main topics. The first one focuses on the urban serving as a support for spatial and cultural strategies in urban redevelopment projects. The second one is related to the potential of micro urban interventions as a strategy for a wider involvement of inhabitants...
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Participatory Budgeting in Poland – Missing Link in Urban Regeneration Process
PublikacjaIn last thirty years Poland has gone a long way toward democracy and decentralization. Role of public participation in planning is increasing rapidly and recently many new instruments of empowering the community is being introduced, participatory budgeting is one of the most important. On the other hand, urban regeneration is one of the most important challenges of polish cities are facing. Technical and transport infrastructure...
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Participatory approach to urban regeneration processes in polish cities and regions
PublikacjaThe paper presents the impact of EU Cohesion Policy 2014-2020 on regeneration processes which are implemented in Polish towns, cities and metropolis when emphasizing general formal and legal framework including examination of the possible distribution of EU funds for regeneration projects within the regional operational programmes. The paper focuses on different approaches to the implementation of Cohesion Policy in Polish regions....
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NEIGHBOURHOOD SPORT AS A TOOL OF URBAN REGENERATION - A WARSAW CASE STUDY
PublikacjaThere are many connections between sport and urban regeneration. They can be observed while organizing top-down projects, such as sporting mega-events. But sport and urban renewal can also be linked within bottom-up sport initiatives, ones that relate mostly to physical recreation or sport for all. The main goals of physical activity is caring for health, improving fitness, practicing hobbies, and achieving social integration....
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Wet H2S corrosion and degradation of pipeline in amine regeneration system
PublikacjaThe paper presents the results of NDT examinations, metallographic tests and risk assessment of degradation related to corrosion of amine regeneration unit in a desulphurisation system. Intensive corrosion resulting from acid gases environment upon water condensation causes perforation of the pipeline. Detailed analysis reveals cracking related to the mechanism of wet H2S. Hydrogen penetration, resulting from the wet H2S process,...
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Fifth generation light sources
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New generation artificial larynx
PublikacjaCelem badań opisanych w pracy było opracowanie urządzeń nowej generacji dla osób laryngektomowanych. Typowa sztuczna krtań ma wiele wad. Najpoważniejszym problemem jest warkot generowany przez urządzenie. Zaproponowane zostały dwa rozwiązania majace na celu wyeliminowania tego problemu. Pierwsze skupia się na zmianach w konstrukcji sztucznej krtani. Opracowane urządzenie zostało dodatkowo wyposażone w cyfrowy procesor i wzmacniacz....
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Heat generation by impulse ultrasound.
PublikacjaOryginalna metoda zastosowana dla wyprowadzenia równaniaewolucyjnego dla ogrzewania środowiska przez falę akustycznądowolnej natury, w tym nieokresowej. Przedstawiono przykłady obliczeń numerycznych.
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Cardinal regenerative features of the MRL mouse
PublikacjaIn this review, we discuss recent studies relating to major features of adult MRL mouse biology that contribute to the regenerative responses seen. These include an increased inflammatory cell profile, a unique glycolytic metabolic state typically found during embryogenesis, and a cell cycle phenotype of DNA damage and G2/M arrest. These traits have been found in other mammalian and non-mammalian regenerative systems. How these...
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The Use of Big Data in Regenerative Planning
PublikacjaWith the increasing significance of Big Data sources and their reliability for studying current urban development processes, new possibilities have appeared for analyzing the urban planning of contemporary cities. At the same time, the new urban development paradigm related to regenerative sustainability requires a new approach and hence a better understanding of the processes changing cities today, which will allow more efficient...
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Big Data in Regenerative Urban Design
PublikacjaWhy the use of Big Data in regenerative planning matters? The aim of this chapter is to study under what conditions Big Data can be integrated into regenerative design and sustainable planning? Authors seek to answer how – when related to the ecosystem and to human activities – Big Data can be used to: • both shape policies that support the development of regenerative human settlements, • support restorative design for practitioners...
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Amine-Based Ionic Liquid for CO2 Capture and Electrochemical or Thermal Regeneration
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Process modeling inside cylinder in an internal combustion engine with heat regeneration
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Treatment of effluents from the regeneration of ion exchangers using the MD process
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Osmotic membrane distillation with continuous regeneration of stripping solution by natural evaporation
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Successfull urban regeneration project: Gdansk-Letnica district case study
PublikacjaThe paper presents the process of urban regeneration of Gdansk Letnica district, a project that from a very short time perspective can be described as successful. The paper present a brief district's history as well as analysis of circumstances that may have influenced Gdansk authorities' decision of starting an urban regeneration project.
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Epigenetic regulation and regeneration: the search for differentially methylated genes in the MRL mouse
PublikacjaThe MRL mouse is an inbred laboratory strain, which was developed in the 60’s of the 20th century and has been extensively used as a model of lupus erythematosus. The regenerative abilities of the strain were discovered in the 90' when the MRL mouse was shown to close 2 mm hole punches made in the ear pinnae four weeks after injury without scarring. The phenomenon has not been observed in other mouse strains, where the holes...
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Analysis of electricity generation variability in 2019 with special consideration of electrical energy generation from wind sources.
PublikacjaThis article presents issues related to the broadly understood development of wind energy. The state of the art of wind energy in the world has been discussed. This paper also shows issues related to factors affecting the development of renewable energy sources and their impact on the natural environment on the basis of available research. The focus is, however, on the critical analysis of phenomena in the data of the Transmission...
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The Challenges Of The Next Generation Leader 5.0
Publikacjahttp://ak.aos.sk/images/repozitar/zborniky/NTPP_clanky23/10_Balcerzyk.pdf
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Generation of charge carriers pairs in tetracene.
PublikacjaBadano mechanizmy odpowiedzialne za fotogenerację nośników ładunku w polikrystalicznych warstwach tetracenu.