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Wyniki wyszukiwania dla: DŁAWIK KOMPENSACYJNY
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Inhibition of Human and Yeast 20S Proteasome by Analogues of Trypsin Inhibitor SFTI-1
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Inhibitors of Matriptase‐2 Based on the Trypsin Inhibitor SFTI‐1
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Experimental and first-principles studies of high-pressure effects on the structural, electronic, and optical properties of semiconductors and lanthanide doped solids
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Paraffin-Embedded Tissue as a Novel Matrix in Metabolomics Study: Optimization of Metabolite Extraction Method
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Photoluminescence enhancement study in a Bi-doped Cs2AgInCl6 double perovskite by pressure and temperature-dependent self-trapped exciton emission
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Synthesis and photochemical characteristics of novel tribenzoporphyrazines possessing peripherally annulated tetrahydrodiazepine and diazepine rings
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Effect of pine essential oil and rotating magnetic field on antimicrobial performance
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Evaluation of differences in expression pattern of three isoforms of the transforming growth factor beta in patients with lumbosacral stenosis
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Nowy polski katalog typowych konstrukcji nawierzchni podatnych i półsztywnych
PublikacjaPrzyczyny opracowania i nowowprowadzone elementy katalogu. Uporządkowanie terminologii. Obliczenia ruchu projektowego i nowe współczynniki przeliczeniowe. Nowe materiały i technologie oraz klasyfikacja warunków gruntowo-wodnych. Projektowanie warstw wzmacniających podłoże gruntowe i górnych warstw nawierzchni.
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Evaluation of the Influence of Farming Practices and Land Use on Groundwater Resources in a Coastal Multi-Aquifer System in Puck Region (Northern Poland)
PublikacjaThis study focuses on the modeling of groundwater flow and nitrate transport in a multi-aquifer hydrosystem in northern Poland, adjacent to Puck Bay (Baltic sea). The main goal was to investigate how changes in land use and farming practices may affect groundwater recharge and submarine groundwater discharge (SGD) to the sea and the associated N-NO3 fluxes. An integrated modelling approach has been developed, which couples the...
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Opracowanie nowego "Katalogu typowych konstrukcji nawierzchni podatnych i półsztywnych"
PublikacjaReferat zawiera opis prac badawczych i projektowych przeprowadzonych na Politechnice Gdańskiej w celu opracowania nowego katalogu. Prace te obejmowały normalizację terminologii, studia istniejących katalogów i metod projektowych w innych krajach, analizy kryteriów zmęczeniowych do projektowania konstrukcji nawierzchni, analizy ruchu projektowego na podstawie danych ze stacji ważenia w ruchu, metody wzmacniania podłoża gruntowego,...
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Assessing groundwater vulnerability to sea water intrusion in the coastline of the inner Puck Bay using GALDIT method
PublikacjaIn this research, GALDIT method was used to assess seawater intrusion in the coastal aquifer of the inner Puck Bay (Southern Baltic Sea). The impact of potential sea-level rise on groundwater vulnerability for years 2081-2100 was also considered. The study area was categorized into three classes of vulnerability: low, moderate and high. The most vulnerable area is the Hel Peninsula with northern part of the Kashubian Coastland....
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Estimation of Conservative Contaminant Travel Time through Vadose Zone Based on Transient and Steady Flow Approaches
PublikacjaEstimation of contaminant travel time through the vadose zone is needed for assessing groundwater vulnerability to pollution, planning monitoring and remediation activities or predicting the effect of land use change or climate change on groundwater quality. The travel time can be obtained from numerical simulations of transient flow and transport in the unsaturated soil profile, which typically require a large amount of data and...
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Assessing groundwater vulnerability to sea water intrusion in the coastline of the inner Puck Bay using GALDIT method
PublikacjaIn this research, GALDIT method was used to assess seawater intrusion in the coastal aquifer of the inner Puck Bay (Southern Baltic Sea). The impact of potential sea-level rise on groundwater vulnerability for years 2081-2100 was also considered. The study area was categorized into three classes of vulnerability: low, moderate and high. The most vulnerable area is the Hel Peninsula with northern part of the Kashubian Coastland....
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Studying road restraint systems to develop new guidelines
PublikacjaThe paper will present a proposed approach to such work along with preliminary results of numerical studies for selected problems using road safety devices such as safety barriers on horizontal curves, the effect of kerbs on bridges or the location of obstacles within the barrier’s working width. The paper will discuss assumptions to a methodology of numerical models, calculations and automated processing of data to help with assessing...
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New polish catalogue of typical flexible and semi-rigid pavements
PublikacjaThe paper covers the following topics important for the development of the new Polish Catalogue of typical flexible and semi-rigid pavements: reasons for preparing the new issue of the Catalogue of typical flexible and semi-rigid pavements, items introduced in the new issue, organise the terminology related to pavements, design traffic calculations and new equivalent axle load factors,...
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Symulacje numeryczne stalowej bariery ochronnej na łuku drogi
PublikacjaW pracy wymieniono pewne czynniki związane z bezpieczeństwem ruchu drogowego, wskazując łuki poziome dróg jako miejsca, gdzie występuje istotna liczba groźnych w skutkach wypadków. W części pracy obejmującej symulacje numeryczne, zrealizowano serię badań spełniających warunki testu zderzeniowego TB11 ze zmiennym promieniem bariery. Oszacowano wpływ zróżnicowania geometrii na parametry bezpieczeństwa.
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Numerical Analysis of TB32 Crash Tests for 4-cable Guardrail Barrier System Installed on the Horizontal Convex Curves of Road
PublikacjaHorizontal curves are one of the elements of road infrastructure where statistically a relatively high number of accidents have been reported. In the last ten years in Poland approx. 10% of all road accidents happened on horizontal curves of roads and was responsible for approx. 14% of all fatalities on Polish roads. Thus, this issue is important and requires extensive research and proper road safety treatments. One possible measure...
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Katalog typowych konstrukcji nawierzchni podatnych i półsztywnych
PublikacjaKatalog zawiera metodę projektowania konstrukcji nawierzchni podatnych i półsztywnych obowiązującą w Polsce.
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Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases
PublikacjaFourteen monocyclic analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds were synthesized by the solid-phase method. The purpose of this work was to establish the role of a disulfide bridge present in inhibitor's side chains of Cys3 and Cys11 in association with serine proteinases. This cyclic fragment was replaced by the disulfide bridges formed by L-pencillamine (Pen), homo-L-cysteine (Hcy), N-sulfanylethylglycine...
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Analogues of trypsin inhibitor SFTI-1 modified in the conserved P1′ position by synthetic or non-proteinogenic amino acids retain their inhibitory activity
PublikacjaA series of linear and monocyclic (with a disulfide bridge only) analogues of trypsin inhibitor SFTI-1 modified in the P-1 and/or P-1' positions were synthesized by the solid-phase method. In the substrate specificity P-1 position, Phe or N-benzylglycine (Nphe) were introduced, whereas the conserved Ser6 in Bownam-Birk (BBI) inhibitors was replaced by Hse (L-homoserine), Nhse [N-(2-hydroxyethyl)glycine], Sar, and Ala. Kinetic studies...
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Injectable bone cement based on magnesium potassium phosphate and cross-linked alginate hydrogel designed for minimally invasive orthopedic procedures
PublikacjaBone cement based on magnesium phosphate has extremely favorable properties for its application as a bioactive bone substitute. However, further improvement is still expected due to difficult injectability and high brittleness. This paper reported the preparation of novel biocomposite cement, classified as dual-setting, obtained through ceramic hydration reaction and polymer cross-linking. Cement was composed of magnesium potassium...
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Remediation of soils on municipal rendering plant territories using Miscanthus × giganteus
PublikacjaPhytoremediation, as a cost-effective, highly efficient, environmentally friendly, and green approach, gained attention to the removal of metals, including heavy metals, from contaminated soils. The toxic nature of heavy metals can have an adverse effect on human health and the ecosystem, and their removal remains a worldwide problem. Therefore, in this study, a field experiment was carried out to evaluate the potential of Miscanthus × giganteus...
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Impact of rotor geometry optimization on the off-design ORC turbine performance
PublikacjaThe paper describes the method of CFD based Nelder-Mead optimization of a 10 kW single-stage axial turbine operating in an ORC system working on R7100. The total-to-static isentropic efficiency is defined as an objective function. Multi-point linear regression is carried out to determine the significance of the objective function arguments and to pick up the set of particular variables and characteristic quantities (e.g. flow angles)...
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In vitro enzyme kinetics and NMR-based product elucidation for glutathione S-conjugation of the anticancer unsymmetrical bisacridine C-2028 in liver microsomes and cytosol: major role of glutathione S-transferase M1-1 isoenzyme
PublikacjaThis work is the next step in studying the interplay between C-2028 (anticancer-active unsymmetrical bisacridine developed in our group) and the glutathione S-transferase/glutathione (GST/GSH) system. Here, we analyzed the concentration- and pH-dependent GSH conjugation of C-2028 in rat liver microsomes and cytosol. We also applied three recombinant human GST isoenzymes, which altered expression was found in various tumors. The...
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The effect of multiaxial geocomposite reinforcement on fatigue performance and crack propagation delay in double-layered asphalt beams
PublikacjaThe presented study investigates the effect of a recently developed multiaxial geocomposite made of polypropylene geogrid and non-woven fabric on the delay of crack propagation, based on four-point bending tests of large asphalt concrete beams – both for reinforced and non-reinforced specimens. Several approaches are described in this study, including analysis of stiffness modulus decrease and analysis of crack propagation using...
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System sterowania oświetleniem w istniejącej infrastrukturze sieci elektrycznej
WynalazkiPrzedmiotem wynalazku jest sposób modernizacji systemu sterowania oświetleniem w istniejącej infrastrukturze sieci elektrycznej bez konieczności wprowadzania zmian w okablowaniu podtynkowym. Nowy system ma umożliwić wprowadzenie niezbędnych modernizacji w istniejącej już infrastrukturze, bez konieczności ingerencji w substancji budynku celem np. dotarcia do okablowania. Istotą wynalazku jest przedstawienie rozwiązania...
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Podstawy BIM (2022-2023 zima)
Kursy Onlineobieralny dla II sem mgr
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Podstawy BIM (2023-2024 zima)
Kursy Onlineobieralny dla II sem mgr
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Robert Piotrowski dr hab. inż.
OsobyRobert Piotrowski jest absolwentem Wydziału Elektrotechniki i Automatyki (2001r., kierunek: Automatyka i Robotyka) oraz Wydziału Zarządzania i Ekonomii (2002r., kierunek: Organizacja Systemów Produkcyjnych) Politechniki Gdańskiej. Od 2005 roku jest zatrudniony na Wydziale Elektrotechniki i Automatyki, aktualnie w Katedrze Inteligentnych Systemów Sterowania i Wspomagania Decyzji. W 2005 roku obronił rozprawę doktorską (Automatyka...
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Data from environmental sensors installed in two locations
Dane BadawczeThe dataset contains data gathered from environmental sensors installed in two locations:
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Objective, observer-independent evaluation of myocardial perfusion and function: the role of SPECT
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Eligible-and-enrolled vs. eligible-but-not-enrolled patients with chronic ischaemic heart failure in randomized clinical trials of myocardial regeneration
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Same but different — Molecular comparison of human KTI12 and PSTK
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Designing Lubricating Properties of Vegetable Base Oils
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Protein overproduction alters exosome secretion in Chinese hamster ovary cells
PublikacjaDespite the abundance of available cell lines, nearly 70% of all recombinant therapeutic proteins today are produced in Chi-nese hamster ovary (CHO) cells. The impact of protein overproduction on the secretion of exosomes by CHO cells has been investigated here. Increased secretion of extracellular vesicles (EVs) by protein overexpressing CHO cells was demonstrated with protein content assay, nanoparticle tracking analysis, and...
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Ability of Yeast Metabolic Activity to Reduce Sugars and Stabilize Betalains in Red Beet Juice
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Pro-Health and Anti-Cancer Activity of Fungal Fractions Isolated from Milk-Supplemented Cultures of Lentinus (Pleurotus) Sajor-caju
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Chromatin-associated microprocessor assembly is regulated by the U1 snRNP auxiliary protein PRP40
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Towards application of uncertainty quantification procedure combined with experimental procedure for assessment of the accuracy of the DEM approach dedicated for granular flow modeling
PublikacjaThere is a high demand for accurate and fast numerical models for dense granular flows found in many industrial applications. Nevertheless, before numerical model can be used its need to be always validated against experimental data. During the validation, it is important to consider how the measurement data sets, as well as the numerical models, are affected by errors and uncertainties. In this study, the uncertainty quantification...
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METODA ELEMENTÓW SKOŃCZONYCH - ZASTOSOWANIA, r.a. 2022/2023, sem. letni
Kursy OnlinePrzedmiot ma na celu zapoznanie studentów z wybranymi aspektami praktycznego zastosowania MES w inżynierii.
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Projektowanie Dróg i Autostrad - (Budownictwo, 1 st., 6. sem., 2022-2023) - Przedmiot obieralny
Kursy OnlineKurs przeznaczony dla studentów I stopnia studiów dziennych na kierunku Budownictwo, którzy wybrali przedmiot obieralny "Projektowanie Dróg i Autostrad".
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Projektowanie Dróg i Autostrad - (Budownictwo, 1 st., 6. sem., 2023-2024) - Przedmiot obieralny
Kursy OnlineKurs przeznaczony dla studentów I stopnia studiów dziennych na kierunku Budownictwo, którzy wybrali przedmiot obieralny "Projektowanie Dróg i Autostrad".
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Cyanido-Bridged Clusters with Remote N-Oxide Groups for Branched Multimetallic Systems
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The impact of resistance exercise range of motion on the magnitude of upper-body post-activation performance enhancement
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Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin
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Cyclic Peptidic Furin Inhibitors Developed by Combinatorial Chemistry
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Multispecies invasion reduces the negative impact of single alien plant species on native flora
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Badania systemów powstrzymujących pojazd przed wypadnięciem z drogi - cz. I
PublikacjaTransportation systems are designed and used so as to effectively and safely relocate people, goods and services. Despite this there are numerous hazards that disrupt or damage these systems. Risks such as extreme weather conditions, terrorist threats, landsliders or earthquakes are difficult to predict, manage and mitigate. One of the hazards for transportation systems are accidents, and their impact on the transport functioning...
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The effects of vehicle restraint systems on road safety
PublikacjaKey to understanding the needs and tools of road infrastructure management for preventing run-off-road crashes or minimising their consequences, is to identify the hazads and sources of hazards caused by wrong or improper use of road safety devices and identify errors in the desifn, structure, construction and operation of road safety devices. Studying such an extended scope of the problem required fieldwork and surveys with road...