Filtry
wszystkich: 1159
-
Katalog
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: chiral pharmaceuticals
-
Biocatalytic Functionalities of Lignin Peroxidase‑Based Systems in Lignin Depolymerization and Pollutants Removal from Environmental Matrices
PublikacjaPurpose of Review In the presented review, we have summarized and highlighted recent developments in the use of lignin peroxidase (LiP) to remove a variety of pollutants from water matrices. The high redox potential of LiP is underlined by its excellent catalytic functionalities in the elimination of pharmaceuticals, phenolics, dyes, polycyclic aromatic hydrocarbons (PAHs), endocrine-disrupting chemicals (EDCs), and other miscellaneous...
-
Permeability of the small intestinal mucus for physiologically relevant studies: Impact of mucus location and ex vivo treatment
PublikacjaThe small intestinal mucus is a complex colloidal system that coats the intestinal mucosa. It allows passage on nutrients/pharmaceuticals from the gut lumen towards the epithelium, whilst preventing it from direct contact with luminal microorganisms. Mucus collected from intestinal tissue is often used in studies looking at inter-mucosal transport of food particulates, drug carriers, etc. However, detaching the highly hydrated...
-
Jerzy Konorski dr hab. inż.
OsobyJerzy Konorski otrzymał tytuł mgr inż. telekomunikacji na Poitechnice Gdańskiej, zaś stopień doktora n.t. w dyscyplinie informatyka w Instytucie Podstaw Informatyki PAN. W r. 2007 obronił rozprawę habilitacyjną na Wydziale Elektroniki, Telekomnikacji i Informatyki PG. Jest autorem ponad 150 publikacji naukowych, prowadził projekty naukowo-badawcze finansowane ze środków Komitetu Badań Naukowych, UE, US Air Force Office of Scientific...
-
Chinese Law Research Guide
PublikacjaA journey of a thousand miles begins with a single step. This Research Guide will be the first step in your journey with Chinese law. China grows more important every day from a global perspective. However, studying and conducting research on Chinese law can be extremely challenging, especially if you do not know Mandarin well. This book is intended as a compact but comprehensive research guide that would provide students (especially...
-
Double layer adhesive silicone dressing as a potential dermal drug delivery film in scar treatment
PublikacjaThe present studies focused on the evaluation of design of an adhesive silicone film intended for scar treatment. Developed silicone double layer film was examined in terms of its future relevance to therapy and applicability on the human skin considering properties which included in vitro permeability of water vapor and oxygen. In order to adapt the patches for medical use in the future there were tested such properties as...
-
Polymeric micelle-mediated delivery of half-sandwich ruthenium(II) complexes with phosphanes derived from fluoroloquinolones for lung adenocarcinoma treatment
Publikacja -
Advanced oxidation treatment of Pentoxifylline in aqueous solution
PublikacjaThe degradation of pentoxifylline (PTX) using H2O2, UV, H2O2/UV, Fenton and photo- Fenton processes has been examined in aqueous solution. The influence of various amount of oxidation agent on H2O2, H2O2/UV, Fenton and photo-Fenton reactions were investigated. Initial PTX concentration in Fenton and photo-Fenton was considerated. The addition of inorganic ions (Cl-, NO3-, SO42- and CO32-) on the degradation efficiency of PTX were...
-
Ongoing Progress on Pervaporation Membranes for Ethanol Separation
PublikacjaEthanol, a versatile chemical extensively employed in several fields, including fuel production, food and beverage, pharmaceutical and healthcare industries, and chemical manufacturing, continues to witness expanding applications. Consequently, there is an ongoing need for cost-effective and environmentally friendly purification technologies for this organic compound in both diluted (ethanol-water–) and concentrated solutions (water-ethanol–)....
-
Biopolymer based nanomaterials in drug delivery systems: A review
PublikacjaDrug delivery systems (DDS) are used to achieve a higher therapeutic effects of a pharmaceutical drug or natural compound in a specific diseased site with minimal toxicological effect and these systems consists of liposomes, microspheres, gels, prodrugs and many. Nanotechnology is a rapidly developing multi-disciplinary science that ensures the fabrication of the polymers to nanometer scale for various medical applications. Uses...
-
Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science)
Czasopisma -
Metody analizy struktury elektronowej ciał stałych
Kursy Online -
XRD data of V2AlC, Mo3AlC2, Mo3CTx and V2AlCTx
Dane BadawczeRaw data for XRD diffractograms of MAX phases: V2AlC and Mo3AlC2 and corresponding MXenes after selective etching of Al.
-
Watershed characteristics and climate factors effect on the temporal variability of mercury in the southern Baltic Sea rivers
Publikacja -
Distribution of mercury in different environmental compartments in the aquatic ecosystem of the coastal zone of the Southern Baltic Sea
Publikacja -
Characterization of the fate of lipids in activated sludge
PublikacjaPrzeprowadzono doświadczenie wykazujące transformację lipidów w aerobowych warunkach osadu czynnego. Wykazano, że całkowitej, początkowej zawartości lipidów (2000 mg/l) nie udało się obniżyć do wartości niższej niż 300 mg/l. Jednakże, zawartość poszczególnych kwasów tłuszczowych uległa drastycznym zmianom, zarówno spadkowi, jak i wzrostowi podczas wszystkich faz wzrostu mikrobiologicznego. Obserwowane zmiany zawartości indywidualnych...
-
Impact of soluble organic matter and particulate organic matter on anammox system: Performance, microbial community and N2O production
PublikacjaIn this study, the effects of soluble readily biodegradable COD (sCOD) and particulate slowly biodegradable COD (pCOD) on anammox process were investigated. The results of the longterm experiment indicated that a low sCOD/N ratio of 0.5 could accelerate the anammox and denitrification activity, to reach as high as 84.9% ±2.8% TN removal efficiency. Partial denitrification-anammox (PDN/anammox) and denitrification were proposed...
-
Singlet oxygen-dominated peroxymonosulfate activation by layered crednerite for organic pollutants degradation in high salinity wastewater
PublikacjaAdvanced oxidation processes have been widely studied for organic pollutants treatment in water, but the degradation performance of radical-dominated pathway was severely inhibited by the side reactions between the anions and radicals, especially in high salinity conditions. Here, a singlet oxygen (1O2)-dominated non-radical process was developed for organic pollutants degradation in high salinity wastewater, with layered crednerite...
-
Estimating the Impact of Globalization on International Competitiveneess : a Multidimensional Approach
PublikacjaThis paper examines the effects of globalization on international competitiveness (IC). The aggregated and disaggregated indices of IC (World Economic Forum) and globalization (KOF) for 132 countries in 2008 are used for the estimation of regression functions. The results show that globalization positively influences IC at the highest aggregation levels of the indices used. Social and political globalization affect IC at intermediate...
-
Asian Powers in Eu Policy
PublikacjaEU policy towards Japan, China, India and South Korea has evolved. This allows the separation of its three stages: before the EU, early EU and mature EU. The global ambitions of the EU, as expressed, inter alia, for the CFSP, is determined to strengthen cooperation with Asian powers, as well as strategic partnerships. The powerful attributes of the strongest Asian states are varied. On the one hand the many similarities and common...
-
Wastewater treatment by means of advanced oxidation processes based on cavitation – A review
PublikacjaHydrodynamic and acoustic cavitation combined with advanced oxidation processes (AOPs), including, among others, the Fenton process, is a promising alternative to the technologies of wastewater treatment technologies in use today. The present review discusses processes based on cavitation combined with AOPs and evaluates their effectiveness in oxidation of organic contaminants. Complete degradation of, among others, p-nitrotoluene,...
-
Detection of low- and high-frequency rhythms in the variability of skin sympathetic nerve activity
Publikacja -
Influence of Binders and Lightweight Aggregates on the Properties of Cementitious Mortars: From Traditional Requirements to Indoor Air Quality Improvement
Publikacja -
Integration of natural and artificial intelligence in production systems
PublikacjaIntegration processes play an increasingly important role in modern economy, and seriously co-decide about the effectiveness of the company. Integration phase occurs in the system life cycle by preceding the final stages of its implementation and activation. In turn, used in software engineering (SE) iteration-evolutionary models, such as spiral model make that the integration activities can occur in varying degrees in all phases...
-
Marek Tobiszewski dr hab. inż.
OsobyUrodzony 07.04.1984 roku w Gdańsku. W 2012 roku obronił z wyróżnieniem doktorat, w 2017 roku uzyskał habilitację na podstawie osiągnięcia naukowego „Opracowanie służących do oceny uciążliwości środowiskowej procedur analitycznych i rozpuszczalników”. Pracuje w Katedrze Chemii Analitycznej od 2012 roku. Jego zainteresowania naukowe łączą analitykę chemiczną, zwłaszcza analityka związków organicznych w próbkach środowiskowych, z...
-
Chronic gastritis, unspecified - Female, 79 - Tissue image [4140730008822971]
Dane BadawczeThis is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Chronic without haemorrhage or perforation - Male, 62 - Tissue image [4140730008823991]
Dane BadawczeThis is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Chronic gastritis, unspecified - Female, 79 - Tissue image [4140730008826891]
Dane BadawczeThis is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Chronic gastritis, unspecified - Male, 58 - Tissue image [409073000792721]
Dane BadawczeThis is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Chronic gastritis, unspecified - Male, 58 - Tissue image [4090730007923811]
Dane BadawczeThis is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Application of Multivariate Adaptive Regression Splines (MARSplines) Methodology for Screening of Dicarboxylic Acids Cocrystal Using 1D and 2D Molecular Descriptors
PublikacjaDicarboxylic acids (DiAs) are probably one of the most popular cocrystals formers. Due to the high hydrophilicity and non-toxicity, they are promising solubilizes of active pharmaceutical ingredients (APIs). Although DiAs appear to be highly capable of forming multicomponent crystals with various compounds, some systems reported in the literature are physical mixtures the solid state without forming stable intermolecular complex....
-
Development of an orbital shaker-assisted fatty acid-based switchable solvent microextraction procedure for rapid and green extraction of amoxicillin from complex matrices: Central composite design
PublikacjaIn this study, a cheap, fast and simple orbital shaker-assisted fatty acid-based switchable solvent microextraction (OS-FASS-ME) procedure was developed for the extraction of amoxicillin (AMOX) in dairy products, pharmaceutical samples and wastewater prior to its spectrophotometric analysis. Fatty acid-based switchable solvents were investigated for extracting AMOX. The key factors of the OS-FASS-ME procedure were optimized using...
-
Chromatographic separation, determination and identification of ecdysteroids: Focus on Maral root (Rhaponticum carthamoides, Leuzea carthamoides )
PublikacjaThe review presents general principles for choosing optimal conditions for ecdysteroid separation, identification, and isolation using HPLC/TLC techniques in RP, NP- HILIC or NP modes. Analytics of ecdyteroids pose a still insufficiently resolved problem. Plant-derived ecdysteroids are a point of interest of pharmaceutical industry and sport medicine due to their postulated adaptogenic and anabolic properties. In insects, ecdysteroids...
-
Recent developmentsinthesynthesisand biological activityofacridine/acridoneanalogues
PublikacjaMany people in the world struggle with cancer or bacterial, parasitic, viral, Alzheimer's and other diseases. Therefore, many scientists seek new, more effective, more selective and less toxic drugs. Acridine/acridone derivatives constitute a class of compounds with a broad spectrum of biological activity and are of great interest to scientists. Todate, many acridine/acridone analogues have been obtained,which, inter alia, exhibit...
-
Estimation of time-frequency complex phase-based speech attributes using narrow band filter banks
PublikacjaIn this paper, we present nonlinear estimators of nonstationary and multicomponent signal attributes (parameters, properties) which are instantaneous frequency, spectral (or group) delay, and chirp-rate (also known as instantaneous frequency slope). We estimate all of these distributions in the time-frequency domain using both finite and infinite impulse response (FIR and IIR) narrow band filers for speech analysis. Then, we present...
-
Comparative molecular dynamics study of dimeric and monomeric forms of HIV-1 protease in ligand bound and unbound state
PublikacjaHuman immunodeficiency virus type 1 protease (HIV-1 PR) is a viral-encoded enzyme that forms a homodimer. HIV-1 PR is essential for replication and assembly of the virus and inactivation of HIV-1 PR enzyme causes production of immature, noninfectious viral particles and thus HIV-1 PR is an attractive target in anti-AIDS drug design. In our current work, we performed molecular dynamics (MD) calculations (500 ns) for two different...
-
Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
PublikacjaThe genome feature of SARS-CoV-2 leads the virus to mutate and creates new variants of concern. Tackling viral mutations is also an important challenge for the development of a new vaccine. Accordingly, in the present study, we undertook to identify B- and T-cell epitopes with immunogenic potential for eliciting responses to SARS-CoV-2, using computational approaches and its tailoring to coronavirus variants. A total of 47 novel...
-
Rhythm and Colours of the Angles
PublikacjaABSTRACT The game of space was and still is a crucial aspect of visual arts. The aim of this study is to examine how the arrangement of hues, rhythms and angles of various polygons can create an impression of depth and movement on a flat surface. The so-called Penrose tiling and Ulam's spiral are mathematical models that have been applied for the painting experiment. There is a vast amount of evidence gathered over the ages that...
-
L'economia mondiale dopo la guerra fredda
PublikacjaChe cosa è successo negli equilibri economici mondiali a partire dal 1989 e dalla dissoluzione del vecchio ordine sovietico? Dopo aver esaminato gli Usa e i suoi competitori asiatici, Giappone e Cina, il libro si concentra sull’Europa e sulle grandi trasformazioni portate dalla riunificazione tedesca, da Maastricht e dalla nascita dell’euro. Infine analizza, nell’ambito della globalizzazione, il ruolo dei BRICS, lo sviluppo economico...
-
Nuclear power plant as a source of electrical energy and heat
PublikacjaIn this paper certain issues concerning usage of nuclear power plants as sources of not only electric power but also thermal energy will be discussed. For such a solution appeals most of all the need to limit harmful emissions of gases (including CO2) and ashes, which come from the process of burning fossil fuels, as well as the raising demand for network heat and chill. Additionally combined heat and power production brings measurable...
-
Model DEA do oceny efektywności funkcjonowania publicznych uniwersytetów w Polsce
PublikacjaPubliczne szkolnictwo wyższe w Polsce, wziąwszy pod uwagę zagrożenia wynikające z sytuacji demograficznej, wymaga analizowania efektywności jego funkcjonowania. W artykule przedstawiono model do pomiaru i oceny efektywności uniwersytetów, uwzględniając pięć podstawowych obszarów ich działalności: badań, rozwoju kadry, dydak-tyki, jakości i finansowania. Zastosowano metodę Data Envelopment Analysis (DEA). Wadą konwencjonalnych modeli...
-
Rapid multi-objective design of integrated on-chip inductors by means of Pareto front exploration and design extrapolation
PublikacjaIdentification of the best trade-offs between conflicting design objectives allows for making educated design decisions as well as assessing suitability of a given component or circuit for a specific application. In case of inductors, the typical objectives include maximization of the quality factor and minimization of the layout area, as well as maintaining a required inductance at a given operating frequency. This work demonstrates...
-
Application of advanced spectroscopic methods in the assessment of the leachability degree of hazardous elements from the matrix of cellular concretea
PublikacjaDue to its structure, autoclaved cellular concrete exhibits good insulating properties with relatively high compressive strength values. It is increasingly used in construction because of its economic attractiveness. Autoclaved cellular concrete is mainly used in interior structure layers, and therefore its potential exposure to heavy metal leaching from the matrix may be related to the presence of a high pH medium from other materials...
-
Modeling of Surface Roughness in Honing Processes by UsingFuzzy Artificial Neural Networks
PublikacjaHoning processes are abrasive machining processes which are commonly employed to improve the surface of manufactured parts such as hydraulic or combustion engine cylinders. These processes can be employed to obtain a cross-hatched pattern on the internal surfaces of cylinders. In this present study, fuzzy artificial neural networks are employed for modeling surface roughness parameters obtained in finishing honing operations. As...
-
Enzyme-linked carbon nanotubes as biocatalytic tools to degrade and mitigate environmental pollutants
PublikacjaA wide array of organic compounds have been recognized as pollutants of high concern due to their controlled or uncontrolled presence in environmental matrices. The persistent prevalence of diverse organic pollutants, including pharmaceutical compounds, phenolic compounds, synthetic dyes, and other hazardous substances, necessitates robust measures for their practical and sustainable removal from water bodies. Several bioremediation and...
-
Molecularly imprinted polymers applied in capillary electrochromatography and electrophoresis techniques
PublikacjaMolecularly imprinted polymers (MIPs) are synthetic materials with predetermined selectivity for a particular analyte or group of structure-linked chemicals which make them an ideal separation component. The process of developing and applying new types of MIPs in the field of environmental analytical chemistry has been broadly discussedi n many scientific studies in recent years. The use of new types of MIP sorbents as unique sorption...
-
Bioactivities of Phenolic Compounds from Kiwifruit and Persimmon
PublikacjaFruit used in the common human diet in general, and kiwifruit and persimmon particularly, displays health properties in the prevention of heart disease. This study describes a combination of bioactivity, multivariate data analyses and fluorescence measurements for the differentiating of kiwifruit and persimmon, their quenching and antioxidant properties. The metabolic differences are shown, as well in the results of bioactivities...
-
Application of BDD thin film electrode for electrochemical decomposition of heterogeneous aromatic compounds
PublikacjaThe aim of the presented study is to investigate the applicability of electrochemical oxidation of aromatic compounds containing heteroatoms, e.g. waste from production of pesticides or pharmaceutics, at a borondoped diamond (BDD) electrode. The BDD electrodes were synthesized by microwave plasma enhanced chemical vapour deposition (MW PE CVD). Investigation of the electrode surface by optical microscopy and scanning electron microscopy...
-
Application of gas chromatographic data and 2D molecular descriptors for accurate global mobility potential prediction
PublikacjaMobility is a key feature affecting the environmental fate, which is of particular importance in the case of persistent organic pollutants (POPs) and emerging pollutants (EPs). In this study, the global mobility classification artificial neural networks-based models employing GC retention times (RT) and 2D molecular descriptors were constructed and validated. The high usability of RT was confirmed based on the feature selection...
-
Hydrophobic (deep) eutectic solvents (HDESs) as extractants for removal of pollutants from water and wastewater – A review
PublikacjaDeep eutectic solvents (DESs) are a new generation of solvents that attracted increasing attention in diverse applications. In last years, growing number of studies on hydrophobic (deep) eutectic solvents (HDESs) as an alternative extractants for various chemicals from aqueous environments have been reported. This article provides an overview on the usage of HDESs in liquid–liquid extraction (LLE) of different pollutants from water...
-
Molecular Design Using Selected Concentration Effects in Optically Activated Fluorescent Matrices
PublikacjaMolecular physics plays a pivotal role in various fields, including medicine, pharmaceuticals, and broader industrial applications. This study aims to enhance the methods for producing specific optically active materials with distinct spectroscopic properties at the molecular level, which are crucial for these sectors, while prioritizing human safety in both production and application. Forensic science, a significant socio-economic...