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Pochodne akrydyny/akrydonu - synteza, aktywność biologiczna i zastosowanie kliniczne = Acridine/acridone derivatives - synthesis, biological activity and clinical application
PublikacjaAkrydyny/akrydony stanowią grupę związków o bardzo szerokim spektrum aktywności biologicznej, stosowanych jako leki przeciwbakteryjne, przeciwpasożytnicze, przeciwmalaryczne, anty-HIV oraz przeciw-nowotworowe. Obecnie dużym zainteresowaniem cieszą się aminokwasowe i peptydowe analogi akrydyny/akrydonu, które mogą znaleźć zastosowanie w leczeniu chorób opartych na terapii genowej oraz w nowoczesnych metodach diagnostycznych (np....
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Hydrogen Production Mechanism in Low-Temperature Methanol Decomposition Catalyzed by Ni3Sn4 Intermetallic Compound: A Combined Operando and Density Functional Theory Investigation
PublikacjaHydrogen production from methanol decomposition to syngas (H2 + CO) is a promising alternative route for clean energy transition. One major challenge is related to the quest for stable, cost-effective, and selective catalysts operating below 400 °C. We illustrate an investigation of the surface reactivity of a Ni3Sn4 catalyst working at 250 °C, by combining density functional theory, operando X-ray absorption spectroscopy, and high-resolution...
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Metal (Mo, W, Ti) Carbide Catalysts: Synthesis and Application as Alternative Catalysts for Dry Reforming of Hydrocarbons—A Review
PublikacjaDry reforming of hydrocarbons (DRH) is a pro-environmental method for syngas production. It owes its pro-environmental character to the use of carbon dioxide, which is one of the main greenhouse gases. Currently used nickel catalysts on oxide supports suffer from rapid deactivation due to sintering of active metal particles or the deposition of carbon deposits blocking the flow of gases through the reaction tube. In this view,...
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Thermochemical Conversion of Biomass and Municipal Waste into Useful Energy Using Advanced HiTAG/HiTSG Technology
PublikacjaAn advanced thermal conversion system involving high-temperature gasification of biomass and municipal waste into biofuel, syngas or hydrogen-rich gas is presented in this paper. The decomposition of solid biomass and wastes by gasification is carried out experimentally with a modern and innovative regenerator and updraft continuous gasifier, among others. A ceramic high-cycle regenerator provides extra energy for the thermal conversion...
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Mieszalnikowa instalacja gazowa w IMP - PAN
PublikacjaW pracy zaproponowana została wstępna koncepcja układu odpowiedzialnego za doprowadzanie paliwa syngazowego (syngaz) do silnika o zapłonie iskrowym. Stworzony układ gazowy ma umożliwić zasilanie dwóch agregatów prądotwórczych – zespołu prądotwórczego ZGT-60/D/MA/PE o mocy ciągłej , oraz drugiego, mniejszego o mocy z 3 cylindrowym silnikiem AD 3.152 –Perkins. Przedstawiona została propozycja wytwarzania niskokalorycznych gazów...
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Rewitalizacja historycznego zespołu pałacowo-parkowego w Lokalnym Programie Rewitalizacji Wejherowa (2008-2015). Revitalisation of the Historic Palace and Park in the Local Revitalisation Program of Wejherowo (2008-2015)
PublikacjaW latach 1990. po upadku komunizmu w Polsce, przestrzeń publiczna w Wejherowie - podobnie jak i w innych miastach Polski była w dużym stopniu zdegradowana. W 2008 roku władze miasta Wejherowa opracowały i zatwierdziły "lokalny program rewitalizacji na lata 2008-2015", który dotyczył głównie centrum miasta. Miał on być w dużym stopniu finansowany przez Unię Europejską..Jedną z najbardziej eksponowanych przestrzeni publicznych, które...
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On the Structure and Volumetric Properties of Solvated Lanthanoid(III) Ions in Amide Solutions
PublikacjaThe coordination chemistry and the volumetric properties of three representative lanthanoid(III) ions lanthanum-(III), gadolinium(III), and lutetium(III) have been studied in three amide solvents with gradually increasing spatial demand upon coordination: N,N-dimethylformamide (dmf)
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Quantum structure in competing lizard communities
PublikacjaAlmost two decades of research on applications of the mathematical formalism of quantum theory as a modeling tool in domains different from the micro-world has given rise to many successful applications in situations related to human behavior and thought, more specifically in cognitive processes of decision-making and the ways concepts are combined into sentences. In this article, we extend this approach to animal behavior, showing...
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Variable-fidelity CFD models and co-Kriging for expedited multi-objective aerodynamic design optimization
PublikacjaPurpose – Strategies for accelerated multi-objective optimization of aerodynamic surfaces are investigated, including the possibility of exploiting surrogate modeling techniques for computational fluid dynamic (CFD)-driven design speedup of such surfaces. The purpose of this paper is to reduce the overall optimization time. Design/methodology/approach – An algorithmic framework is described that is composed of: a search space reduction,...
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WHY SHOULD WE ADOPT NON-USED ATTICS OF MONUMENTAL SACRAL CATHOLIC CHURCHES FOR SECULAR PURPOSES?
PublikacjaA motive for adapting the desecrated churches to new purposes is a broadly discussed matter, progressively better investigated and defined. Is it advisable to introduce a new, permanent function, complementary to the sacred one in the historical ecclesial buildings? This paper presents the results of the research on benefits of adapting the non-utilized attics of monumental churches still performing their sacred function, located...
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Efficient Surrogate Modeling and Design Optimization of Compact Integrated On-Chip Inductors Based on Multi-Fidelity EM Simulation Models
PublikacjaHigh-performance and small-size on-chip inductors play a critical role in contemporary radio-frequency integrated circuits. This work presents a reliable surrogate modeling technique combining low-fidelity EM simulation models, response surface approximations based on kriging interpolation, and space mapping technology. The reported method is useful for the development of broadband and highly accurate data-driven models of integrated...
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Electronic excitation energy migration in partly ordered polymeric films
PublikacjaWieloetapowa migracja energii pomiędzy podłużnymi fluoroforami (karbocyjaniny) w osiowo rozciąganych foliach polimerowych była studiowana na podstawie pomiarów anizotropii emisji i symulacji Monte Carlo. W przeciwieństwie do układów nieuporządkowanych pokazano eksperymentalnie, że stężeniowa depolaryzacja fluorescencji w osiowo orientowanych foliach jest ekstremalnie słaba, mimo tego, że zachodzi zjawisko migracji energii. Opierając...
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Hodgkin lymphoma, nodular sclerosis, NOS - Male, 35 - Tissue image [6290730005945721]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Hodgkin lymphoma, nodular sclerosis, NOS - Male, 35 - Tissue image [6290730005944591]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Hodgkin lymphoma, nodular sclerosis, NOS - Male, 35 - Tissue image [6290730005941641]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Design for all
Kursy OnlineThe aim of the course is to increase awareness of the needs of people with special needs and the idea of universal design. The subject is to introduce the social and legal conditions of the profession of architect, focused on the needs of all vulnerable user groups, including people with disabilities and the elderly. Knowledge of solutions related to Design for All is necessary due to the implementation of directives and standards...
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Theory of architectural design V. Design for all
Kursy OnlineThe aim of the course is to increase awareness of the needs of people with special needs and the idea of universal design. The subject is to introduce the social and legal conditions of the profession of architect, focused on the needs of all vulnerable user groups, including people with disabilities and the elderly. Knowledge of solutions related to Design for All is necessary due to the implementation of directives and standards...
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Fast Multi-Objective Antenna Design Through Variable-Fidelity EM Simulations
PublikacjaA technique for fast multi-objective antenna optimization is introduced. A kriging interpolation surrogate constructed from sampled coarse-mesh EM simulations is utilized by multi-objective evolutionary algorithm (MOEA) to obtain the initial Pareto front approximation. The surrogate is defined in a subset of the original design space, determined by means of independently optimized individual objectives. Response correction techniques...
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A quaternion-based modified feistel cipher for multimedia transmission
PublikacjaIn this paper a quaternion-based modified Feistel Cipher is proposed. The algorithm is based on the scheme proposed by Sastry and Kumar (2012). Our algorithm uses special properties of quaternions to perform rotations of data sequences in 3D space for each of the cipher rounds. The plaintext (image in gray-tone) is divided into two square matrices of equal size which consist of Lipschitz quaternions. A modular arithmetic was implemented...
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Homoclinic and Heteroclinic Orbits for a Class of Singular Planar Newtonian Systems
PublikacjaThe study of existence and multiplicity of solutions of differential equations possessing a variational nature is a problem of great meaning since most of them derives from mechanics and physics. In particular, this relates to Hamiltonian systems including Newtonian ones. During the past thirty years there has been a great deal of progress in the use of variational methods to find periodic, homoclinic and heteroclinic solutions...
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Subharmonic solutions for a class of Lagrangian systems
PublikacjaWe prove that second order Hamiltonian systems with a potential of class C1, periodic in time and superquadratic at infinity with respect to the space variable have subharmonic solutions. Our intention is to generalise a result on subharmonics for Hamiltonian systems with a potential satisfying the global Ambrosetti-Rabinowitz condition from [P. H. Rabinowitz, Proc. Roy. Soc. Edinburgh Sect. A, 114 (1990), 33-38]. Indeed, we weaken...
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The homometallic warwickite V 2 OBO 3
PublikacjaThe synthesis, structure and elementary magnetic characterization of the homometallic warwickite V2OBO3 are reported. The material adopts the orthorhombic warwickite structure type at room temperature, space group Pnma (No. 62) with lattice parameters a = 9.2317(1) Å, b = 3.1172(1) Å, and c = 9.5313(1) Å. Temperature-dependent magnetic susceptibility, electrical resistivity, and specific heat measurements show anomalies near 35 K,...
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Comparison of anti-plane surface waves in strain-gradient materials and materials with surface stresses
PublikacjaHere we discuss the similarities and differences in anti-plane surface wave propagation in an elastic half-space within the framework of the theories of Gurtin–Murdoch surface elasticity and Toupin–Mindlin strain-gradient elasticity. The qualitative behaviour of the dispersion curves and the decay of the obtained solutions are quite similar. On the other hand, we show that the solutions relating to the surface elasticity model...
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Effect of electrode resistance on admittance spectra of planar organic device carrying SCLC and on charge carrier mobility extracted from susceptance
PublikacjaThe work presents small signal admittance spectra of a sandwich system with thin organic layer carrying a space charge limited current. The effect of series resistance of electrodes on the spectra is discussed. Spectra of small signal capacitance are added to get more detailed insight. The analysis performed shows that the series resistance can affect both parts of small signal response within a whole range of frequency. Moreover,...
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Method of lines for Hamilton-Jacobi functional differential equations.
PublikacjaInitial boundary value problems for nonlinear first order partial functional differential equations are transformed by discretization in space variables into systems of ordinary functional differential equations. A method of quasi linearization is adopted. Suffcient conditions for the convergence of the method of lines and error estimates for approximate solutions are presented. The proof of the stability of the diffrential difference...
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Embedded Representations of Wikipedia Categories
PublikacjaIn this paper, we present an approach to building neural representations of the Wikipedia category graph. We test four different methods and examine the neural embeddings in terms of preservation of graphs edges, neighborhood coverage in representation space, and their influence on the results of a task predicting parent of two categories. The main contribution of this paper is application of neural representations for improving the...
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ECONOMIC MEASURES AGAINST A PANDEMICS
PublikacjaThe appropriate level of treatment during periods of increasing workload in the health care system or a particular hospital is ensured either by changing the organization of the system and the principles of use of resources such as space, staff and consumables or their redistribution, or by financial resources such resources are increased or replenished. This article contributes to improve the concept of resource allocation as...
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Hybrid Technique for the EM Scattering Analysis with the Use of Ring Domain Decomposition
PublikacjaA hybrid technique combining finite-element and mode-matching methods for the analysis of scattering problems in open space is presented here. The main idea is based on impedance matrix descriptions of the boundary surrounding the discrete computational domain and combine it with external field described analytically. The discrete analysis, which is the most time- and memory-consuming, is limited here only to the close proximity...
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Design of septic tanks placed on cohesive soils
PublikacjaThe paper presents a short review of literature with regard to design and erection of the reinforced concrete and concrete tanks. The authors investigated the underground septic tank with of 10 m3 capacity placed on cohesive soils. The authors compared the values of internal forces for soils in drained and undrained conditions with different geotechnical parameters: loamy sand of liquidity index IL = 0.1 and IL = 0.7 and clay with...
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Ontology Oriented Approach to Service Selection and Invocation in Complex Context Analysis
PublikacjaContext-aware applications running in the intelligent space are taken into account and their execution in the service oriented environment is considered. It has been presented where and how SOA services can be utilized during their execution: to analyze current context of the application and to support execution of strictly determined actions suitable for that context. The proposed mechanism of context-aware service selection and...
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A Method and Device for 3D Recognition of Cutting Edge Micro Geometry
PublikacjaA very useful method was successfully applied in the investigation of tools for machining wood and wood based composites. It allows scanning of the cutting edge micro geometry in three dimensions and reproducing it in a virtual space as a 3D surface. The application of the method opens new possibilities of studying tool wear by scanning, including the calculation of volume loss and other analysis of tool wedge geometry along and...
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Odczuwanie przestrzeni, czyli architektura jako lekarstwo
PublikacjaRecenzja książki, Esther M. Sternberg, Healing Spaces: The Science of Place and Well-Being , The Belknap press of Harvard University press, 2010, ISBN 978-0-674-05748-7
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Assessing business process complexity based on textual data: Evidence from ITIL IT ticket processing
PublikacjaPurpose This study aims to draw the attention of business process management (BPM) research and practice to the textual data generated in the processes and the potential of meaningful insights extraction. The authors apply standard natural language processing (NLP) approaches to gain valuable knowledge in the form of business process (BP) complexity concept suggested in the study. It is built on the objective, subjective and meta-knowledge...
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Exploring the Solubility Limits of Edaravone in Neat Solvents and Binary Mixtures: Experimental and Machine Learning Study
PublikacjaThis study explores the edaravone solubility space encompassing both neat and binary dissolution media. Efforts were made to reveal the inherent concentration limits of common pure and mixed solvents. For this purpose, the published solubility data of the title drug were scrupulously inspected and cured, which made the dataset consistent and coherent. However, the lack of some important types of solvents in the collection called...
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Strategies for computationally feasible multi-objective simulation-driven design of compact RF/microwave components
PublikacjaMulti-objective optimization is indispensable when possible trade-offs between various (and usually conflicting) design objectives are to be found. Identification of such design alternatives becomes very challenging when performance evaluation of the structure/system at hand is computationally expensive. Compact RF and microwave components are representative examples of such a situation: due to highly compressed layouts and considerable...
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Crystallographic study of self-organization in the solid state including quasi-aromatic pseudo-ring stacking interactions in 1-benzoyl-3-(3,4-dimethoxyphenyl)thiourea and 1-benzoyl-3-(2-hydroxypropyl)thiourea
Publikacja1-Benzoylthioureas contain both carbonyl and thiocarbonyl functional groups and are of interest for their biological activity, metal coordination ability and involvement in hydrogen-bond formation. Two novel 1-benzoylthiourea derivatives, namely 1-benzoyl-3-(3,4-dimethoxyphenyl)thiourea, C₁₆H₁₆N₂O₃S, (I), and 1-benzoyl-3-(2-hydroxypropyl)thiourea, C₁₁H₁₄N₂O₂S, (II), have been synthesized and characterized. Compound (I) crystallizes...
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THE 3D MODEL OF WATER SUPPLY NETWORK WITH APPLICATION OF THE ELEVATION DATA
Publikacja3D visualization is a key element of research and analysis and as the source used by experts in various fields e.g.: experts from water and sewage systems. The aim of this study was to visualize in three-dimensional space model of water supply network with relief. The path of technological development of GESUT data (Geodezyjna Ewidencja Sieci Uzbrojenia Terenu – geodetic records of public utilities) for water supply and measurement...
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Generalization of Phylogenetic Matching Metrics with Experimental Tests of Practical Advantages
PublikacjaThe ability to quantify a dissimilarity of different phylogenetic trees is required in various types of phylogenetic studies, for example, such metrics are used to assess the quality of phylogeny construction methods and to define optimization criteria in supertree building algorithms. In this article, starting from the already described concept of matching metrics, we define three new metrics for rooted phylogenetic trees. One...
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Narracje o świeżej traumie. Upamiętnianie ataków terrorystycznych w krajobrazie codziennym miast
PublikacjaRecent trauma Narratives: commemorating terrorist attacks in Everyday cityscape Contemporary city incidentally becomes a non-accidental target of acts violating the primary sense of security and safety. The fundamental assumptions about so- cial and interpersonal interactions that guarantee social life are severely disturbed. These events, primarily the ones related to terrorist attacks, leave in social memo- ry traces associated...
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Low-Cost Automated Design of Compact Branch-Line Couplers
PublikacjaBranch-line couplers (BLCs) are important components of wireless communication systems. Conventional BLCs are often characterized by large footprints which make miniaturization an important prerequisite for their application in modern devices. State-of-the-art approaches to design of compact BLCs are largely based on the use of high-permittivity substrates and multi-layer topologies. Alternative methods involve replacement of transmission-line...
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Customization of UWB 3D-RTLS Based on the New Uncertainty Model of the AoA Ranging Technique
PublikacjaThe increased potential and effectiveness of Real-time Locating Systems (RTLSs) substantially influence their application spectrum. They are widely used, inter alia, in the industrial sector, healthcare, home care, and in logistic and security applications. The research aims to develop an analytical method to customize UWB-based RTLS, in order to improve their localization performance in terms of accuracy and precision. The analytical...
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Exposure to cooking emitted volatile organic compounds with recirculating and extracting ventilation solutions
PublikacjaEnergy-efficient urban development leads to the compact design of apartments. Recirculating ventilation solutions are an attempt to minimize the space required for ventilation ducting, but more data on their performance are needed. Cooking is a major source of volatile organic compounds (VOCs) emissions. It is necessary to assess how well recirculating kitchen hoods perform in reducing the residents' exposure to cooking fumes compared...
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Hanna Obracht-Prondzyńska dr inż. arch.
OsobyDr inż. arch. Hanna Obracht-Prondzyńska Adiunktka na Uniwersytecie Gdańskim w Zakładzie Gospodarki Przestrzennej, nauczycielka akademicka ucząca projektowania urbanistycznego i analizy danych. Architektka i urbanistka zajmującą się projektowaniem w oparciu o dane. Tytuł doktora nauk inżynieryjno-technicznych w dyscyplinie architektura i urbanistyka obroniła z wyróżnieniem w 2020 r. na Wydziale Architektury Politechniki Gdańskiej,...
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Stan estetyczny przestrzeni a kultura korzystania z miasta
PublikacjaArtykuł jest analizą zagadnień estetyzacji przestrzeni w kontekście kulturowym. Istnieje potrzeba analizy, czy przynajmniej szkicu przybliżającego kulturowe uwarun- kowania kształtowania przestrzeni, które doprowadziły do obecnej sytuacji w polskich miastach. Szkic ten może być jednym z głosów w obecnie prowadzonej dyskusji na temat tak zwanej estetyzacji przestrzeni oraz podej- mowanych przez zainteresowanych decyzji.
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Rola inicjatyw społecznych w ochronie dziedzictwa kulturowego na przykładzie mozaiki Anny Fiszer na ścianie kina Neptun w Gdańsku
PublikacjaStreszczenie: Rola inicjatyw społecznych w ochronie dziedzictwa kulturowego na przykładzie mozaiki Anny Fiszer na ścianie kina Neptun w Gdańsku. Celem artykułu jest wykazanie roli inicjatyw społecznych w budzeniu poczucia odpowiedzialności za dziedzictwo materialne i kulturowe. Przyjęto założenie, że dla lokalnych społeczności miasto jest przestrzenią pamięci. Nastrój, atmosfera i klimat miejsca to słowa, które określają fizyczny...
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Tworzenie miasta przyjaznego wszystkim
PublikacjaTworzenie miasta przyjaznego wszystkim, to zadnie, które jest prawdopodobnie celem wszystkich włodarzy miejskich. Czy nie jest tak, że każdy chciałby w takim mieście zamiesz-kać? Jednak zadanie to jest dość trudne, bo wymaga pogodzenia wielu aspektów życia mieszkańców. Obecnie do zagadnień środowiskowych związanych z szeroko rozumianą ekologią dochodzi zagadnienie dostosowania przestrzeni zgodnie z zasadami projektowania uniwersalnego....
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Comparison of Downdraft and Updraft Gasification of Biomass in a Fixed Bed Reactor
PublikacjaThe aim of this study was to compare and analyze the gasification process of beech wood. The experimental investigation was conducted inside a gasifier, which can be operated in downdraft and updraft gasification system. The most important operating parameter studied in this paper was the influence of the amount of supply air on the temperature distribution, biomass consumption and syngas calorific value. The results show that...
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Inactivation of glucosamine-6-phosphate synthase by N3-oxoacyl derivatives of L-2,3-diaminopropanoic acid
PublikacjaN3-oksoacylowe pochodne kwasu l-2,3-diaminopropanowego zawierające ugrupowanie epoksydowe lub układ sprzężonych wiązań podwójnych inaktywują syntaze glukozamino-6-fosforanu (GlcN-6-P) z S. cerevisiae. Wyniki badań kinetycznych inaktywacji enzymu wskazują na dwuetapowy przebieg tej reakcji, przy czym tworzenie kompleksu enzym:ligand poprzedza nieodwracalną modyfikację enzymu. Badane związki różniły się powinowactwem do centrum aktywnego...
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Automatic Regularization by Quantization in Reducible Representations of CCR: Point-Form Quantum Optics with Classical Sources
PublikacjaElectromagnetic fields are quantized in a manifestly covariant way by means ofa class of reducible "center-of-mass N-representations" of the algebra of canonical commutationrelations (CCR). The four-potential Aa(x) transforms in these representations as aHermitian four-vector field in Minkowski four-position space (without change of gauge), butin momentum space it splits into spin-1 massless photons and two massless scalars. Whatwe...
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Re-thinking the city in the context of suburban landscapes. The case of Visula River delta water - landscapes and urban transformation processes in Gdańsk
PublikacjaThe text draws attention to the significant role of landscape formations surrounding the city and their role in marking out directions for the transformation and development of urban areas with the particular emphasis on public spaces. The article presents the need for a more conscious design strategies that are based on connectedness of urban spaces, which is built on landscape's characteristics, as an essential starting point...