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Wyniki wyszukiwania dla: PROTEIN FOLDING
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Water-mediated long-range interactions between the internal vibrations of remote proteins
PublikacjaIt is generally acknowledged that the mobility of protein atoms and the mobility of water molecules in the solvation layer are connected. In this article, we answer the question whether a similar interdependence exists between the motions of atoms of proteins separated by the hydration layers of variable thickness. The system consisted of a kinesin catalytic domain and a tubulin dimer. It was studied using molecular dynamics simulations....
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International Journal of Material Forming
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China Welding (English Edition)
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SCIENCE AND TECHNOLOGY OF WELDING AND JOINING
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Rotational Molding of Linear Low-Density Polyethylene Composites Filled with Wheat Bran
PublikacjaApplication of lignocellulosic fillers in the manufacturing of wood polymer composites (WPCs) is a very popular trend of research, however it is still rarely observed in the case of rotational molding. The present study aimed to analyze the impact of wheat bran content (from 2.5 wt.% to 20 wt.%) on the performance of rotationally-molded composites based on a linear low-density polyethylene (LLDPE) matrix. Microscopic structure...
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Limit Analysis of a Strip Footing on Stochastic Subsoil.
PublikacjaW pracy analizowana jest ława fundamentowa posadowiona na losowym podłożu.Poszukiwane są oszacowania nośności podłoża na podstawie twierdzeń o dolnej i górnej ocenie obciążenia granicznego. Dla różnych statycznie dopuszczalnych pól naprężenia i kinematycznie dopuszczalnych pól prędkości, wyznaczono wartości oczekiwane i wariancje obciążenia granicznego. Pozwoliło to na określenie odpowiednich dystrybuant, rozumianych...
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Sierpinski Monopole Antenna - Uniplanar Feeding Technique.
PublikacjaPrzedstawiono różne techniki zasilania monopolowych anten fraktalnych typu Sierpinskiego. Zaproponowano nowe sposoby zasilania: poprzez linię współosiową ze zmodyfikowaną rozszerzoną płaszczyzną masy oraz poprzez linię współosiową i falowód koplanarny. W obu przypadkach możliwa była znaczna miniaturyzacja struktury. Wykonane i przebadane prototypy anten potwierdziły przydatność przedstawionych rozwiązań.
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The forming and emission of high power electromagnetic pulses
PublikacjaAn impulse energy source, a power conditioning system and an electromagnetic field emitter are essential to generate an electromagnetic field pulse (EMFP) with a specific frequency bandwidth. Selected simulation results for a power conditioning system consisting of a fuse opening switch and a paraboloidal electromagnetic emitter have been presented in this article. The synthetic system examined in the simulation is powered by...
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Chalcogen bonding interactions in a series of aromatic selenocyanates
PublikacjaSelenium atoms in aromatic selenocyanates are characterized by the occurrence of two σ-holes, a stronger one in the prolongation of the NC–Se bond and a weaker one in the prolongation of the Ar–Se bond. The crystal structures of several bis(selenocyanato) derivatives, prepared by a method originally developed for ortho bis-substituted derivatives, illustrate very well this difference, with a short NC–Se⋯NC ChB interaction organizing...
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JABAT Middleware as a Tool for Solving Optimization Problems
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Analysis of Asymmetrical Rolling Process of Multilayer Plates
PublikacjaW niniejszej pracy przedstawiono wyniki badań numerycznych asymetrycznego procesu walcowania blach wielowarstwowych M1E-Al99,8-AlMg5. Modelowanie numeryczne procesu walcowania blach wielowarstwowych przeprowadzono w programie Forge 2D, którego obliczenia bazują na metodzie elementów skończonych. Przedstawione w pracy wyniki umożliwiły przeprowadzenie analizy procesu walcowania blach wielowarstwowych.
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Tire rolling resistance measurements on the road and in the laboratory
PublikacjaW pracy przedstawiono stanowisko bębnowe do badania oporu toczenia opon samochdowych w warunkach laboratoryjnych. Zaprezentowano także przyczepę dynamometryczną do badania oporu toczenia opon samochodowych w warunkach drogowych. Stanowisko bębnowe i przyczepa zosały zbudowane w Katedrze Pojazdów i Maszyn Roboczych Politechniki Gdańskiej. Omówiono wpływ wzdłużnego pochylenia drogi i naporu powietrza na badane koło na dokładność...
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The lubricant-coating interaction in rolling and sliding contacts
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Fouling in direct contact membrane distillation process
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Totally laparoscopic feeding jejunostomy – a technique modification
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Numerical simulations of S700MC laser and hybrid welding
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Numerical Simulation of Duplex Steel Multipass Welding
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Road texture influence on tyre rolling resistance
PublikacjaTyre performance, one of the critical factors for vehicle users, is strongly related to theroad surface characteristics, most notably to the pavement texture. Phenomena that occur at the tyre/road interface affect tyre friction (skid resistance), rolling resistance, tyre wear and tyre/road noise. This article deals with relationship between surface texture and rolling resistance of light and heavy vehicle tyres. Mean profile depth...
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Hertzian Crack Propagation in Ceramic Rolling Elements
PublikacjaThe properties of ceramics are of most interest to rolling element manufacturers. The influence of ring crack size on rolling contact fatigue failure has been studied using numerical fracture analysis. Such crack are very often found on ceramic bearing balls and decrease fatigue life rapidly. The numerical calculations are based on a three dimensional model for the ring crack propagation. The stress intensity factors along crack...
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Engineering method of tire rolling resistance evaluation
PublikacjaTire rolling resistance is one of the most difficult tire parameters to measure. The reason is that for modern tires the force of rolling resistance corresponds to 0.5–1% of tire load, thus measurements of very small forces must be performed in a heavily loaded system. This constitutes great problems, especially in road conditions. Laboratory measurements are easier to perform, as the environment may be better controlled, but roadwheel...
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An experimental study of high-hydrogen welding processes
PublikacjaThis paper presents investigation results of determination of the diffusible hydrogen content in deposited metal obtained by means of two most often used methods-the glycerin method and the mercury method. Relation has been defined between results of those methods in the area characteristic of low-hydrogen as well as high-hydrogen welding processes. Relations available in the literature do not include the diffusible hydrogen content...
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Road texture influence on tire rolling resistance
PublikacjaTire rolling resistance is one of the most important resistive forces acting on road vehicles. It depends on tire and surface characteristics as well as vehicle operating parameters. This paper deals with the influence of road surface texture on rolling resistance of passenger car tires. Results of road measurements performed on variety of road surfaces are presented.
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Stability of a truss under upward wind loading
PublikacjaThe present paper is devoted to the numerical investigations of stability of a truss under upward wind load. The truss is braced at its the upper cord. A structural variant including lateral braces, or lateral and torsional braces is considered. The research presents the problems of linear buckling and non-linear static analysis of the truss shell and beam model with geometric and material non-linearity are presented. The initial...
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Application of Multivariate Analysis Methods in Welding Engineering
PublikacjaPhenomena and processes taking place during welding are usually very complex and, for this reason, should be described using multivariate methods. The article discusses the methodological basis and selected application areas as regards the solving of welding problems using statistical multivariate methods. In addition, the article presents exemplary applications of the design of experiment, multiple regression analysis, cluster...
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The forming and emission of high power electromagnetic pulses
PublikacjaAn impulse energy source, a power conditioning system and an electromagnetic field emitter are essential to generate an electromagnetic field pulse (EMFP) with a specific frequency bandwidth. Selected simulation results for a power conditioning system consisting of a fuse opening switch and a paraboloidal electromagnetic emitter have been presented in this article. The synthetic system examined in the simulation is powered by an...
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Underwater Local Cavity Welding of S460N Steel
PublikacjaIn this paper, a comparison of the mechanical properties of high-strength low-alloy S460Nsteel welded joints is presented. The welded joints were made by the gas metal arc welding (GMAW)process in the air environment and water, by the local cavity welding method. Welded joints were testedfollowing the EN ISO 15614-1:2017 standard. After welding, the non-destructive—visual, penetrant,radiographic, and ultrasonic (phased array) tests...
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Dissimilar underwater wet welding of HSLA steels
PublikacjaThe high-strength low-alloy S460ML and S460N steels were chosen for underwater wet welding of dissimilar T-joints using covered electrodes. For improving the quality of joints, the temper bead welding (TBW) method was used. The application of TBW in pad welding conditions has been investigated earlier but the possibility of usage of this technique in welded joints was not analyzed. The main aim of the study was to check the influence...
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Evolution towards simplicity in bacterial small heat shock protein system
PublikacjaEvolution can tinker with multi-protein machines and replace them with simpler single-protein systems performing equivalent functions in an equally efficient manner. It is unclear how, on a molecular level, such simplification can arise. With ancestral reconstruction and biochemical analysis, we have traced the evolution of bacterial small heat shock proteins (sHsp), which help to refold proteins from aggregates using either two...
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Modified Peptide Molecules As Potential Modulators of Shelterin Protein Functions; TRF1
PublikacjaIn this work, we present studies on relatively new and still not well-explored potential anticancer targets which are shelterin proteins, in particular the TRF1 protein can be blocked by in silico designed "peptidomimetic" molecules. TRF1 interacts directly with the TIN2 protein, and this protein-protein interaction is crucial for the proper functioning of telomere, which could be blocked by our novel modified peptide molecules....
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Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 54, the 5th joint CASP-CAPRI protein assembly prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo-trimers, 13 heterodimers including 3 antibody–antigen complexes, and 7 large assemblies. On average 70 CASP and CAPRI predictor groups, including more than 20 automatics servers, submitted models for each target. A total of 21 941 models submitted by these groups...
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Simulation of Protein Structure and Dynamics with the Coarse-Grained UNRES Force Field
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Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
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Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment
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Trial Proteomic Qualitative and Quantitative Analysis of the Protein Matrix of Submandibular Sialoliths
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Riboflavin binding protein—Chiral stationary phase: Investigation of retention mechanism
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The Nutritional Value and Biological Activity of Concentrated Protein Fraction of Potato Juice
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Serum Fatty Acid-Binding Protein 4 is Increased in Patients with Psoriasis
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Survivin DEx3 as a biomarker of thyroid cancers: A study at the mRNA and protein level
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Stability of delay induced oscillations in gene expression of Hes1 protein model
PublikacjaW pracy prezentowana jest matematyczna analiza modelu ekspresji genu białka Hes1. Rozważamy układ równań z dwoma opóźnieniami - w produkcji białka Hes1 oraz jego mRNA. Dowodzimy istnienia i jednoznaczności oraz nieujemności rozwiązań. Pokazujemy istnienie dokładnie jednego dodatniego stanu stacjonarnego. Wykazujemy, że stabilność stanu stacjonarnego zależy od sumy opóźnień. Podajemy warunek dostateczny na wystąpienie bifurkacji...
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Novel primosomal protein B from thermophilic bacterium Thermoanerobacter tengcongensis
PublikacjaWe report the identification and characterization of theprimosomal protein B (PriB) from thermophilic bacteriumThermoanerobacter tengcongensis (TtePriB). It is the largestknown bacterial PriB protein consisting 216 amino acidresidues with a calculated molecular mass of 25 kDa. Surprisingly,it is functional as monomer containing two single-stranded DNA binding domain (OB-fold) and it is thecompletely new kind structure of SSB protein....
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CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures
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BALCONY: an R package for MSA and functional compartments of protein variability analysis
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Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines
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C-reactive protein as a diagnostic and prognostic factor in inflammatory bowel diseases
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DSC and electrophoretic studies on protein denaturation of Anodonta woodiana (Lea, 1834)
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Functional Protein Composition in Femoral Glands of Sand Lizards (Lacerta agilis)
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Zeta potential and droplet size of n-tetradecane/ethanol (protein) emulsions
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TOLLIP Protein Expression Predicts Unfavorable Outcome in Renal Cell Carcinoma
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Two-dimensional gel-based serum protein profile of growing piglets
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Effect of Functionalization of Carbon Nanotubes with Psychosine on Complement Activation and Protein Adsorption
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