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Wyniki wyszukiwania dla: CARMINIC ACID
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Extraction pathways and purification strategies towards carminic acid as natural-based food colorant: A comprehensive review
PublikacjaAs a current trend of fabricating healthier products, food manufacturing companies seek for natural-based food colorant aiming to replace the synthetic ones, which apart from meeting sensorial and organoleptic aspects, they can also act as health promoters offering additional added value. Carminic acid is a natural based food colorant typically found in several insect taxa. However, there are current approaches which pursue the...
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AMINO ACIDS
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Investigation of an elutable N-propylphosphonic acid chitosan derivative composition with a chitosan matrix prepared from carbonic acid solution
PublikacjaPorous chitosan composites using CO2 dissolution procedure and including water soluble N-propylphosphonic chitosan derivative (p-CHI) were obtained and characterized. In contrast to the control material, composites containing modified chitosan distinguished by a rapid moisture absorption and good adhesion to the skin. The FTIR analysis confirmed the presence of propylphosphonic group in the structure of the polymer. The porosity...
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NUCLEIC ACIDS RESEARCH
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Nucleic Acid Therapeutics
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Matcha Green Tea: Chemical Composition, Phenolic Acids, Caffeine and Fatty Acid Profile
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Arid Ecosystems
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Bioaccessibility of Phenolic Acids and Flavonoids from Buckwheat Biscuits Prepared from Flours Fermented by Lactic Acid Bacteria
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APPLIED AND COMPUTATIONAL HARMONIC ANALYSIS
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Synthesis and biological activity of mycophenolic acid-amino acid derivatives
PublikacjaIn search of new immunosuppressants, mycophenolic acid (MPA) was coupled with amino acid methyl esters followed by hydrolysis to analogs bearing free carboxylic groups. The obtained compunds were tested in vitro as growth inhibitors of lymphoid cell line (Jurkat) and human peripheral blood mononuclear cells (PBMC) from healthy donors. According to obtained results recovering of free carboxylic group increased their activity. Additionally,...
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Synthesis and biological activity of mycophenolic acid-amino acid derivatives
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Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublikacjaBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
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Immunosuppressive properties of amino acid and peptide derivatives of mycophenolic acid
PublikacjaMycophenolic acid (MPA) was coupled with amino acids and biologically active peptides including derivatives of tuftsin to modify its immunosuppressive properties. Both amino acid unit in the case of simple MPA amides and modifications within peptide moiety of MPA - tuftsin conjugates influenced the observed activity. Antiproliferative potential of the obtained conjugates was investigated in vitro and MPA amides with threonine methyl...
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Hyaluronic acid/tannic acid films for wound healing application
PublikacjaIn this study, thin films based on hyaluronic acid (HA) with tannic acid (TA) were investigated in three different weight ratios (80HA/20TA, 50HA/50TA, 20HA/80TA) for their application as materials for wound healing. Surface free energy, as well as their roughness, mechanical properties, water vapor permeability rate, and antioxidant activity were determined. Moreover, their compatibility with blood and osteoblast cells was investigated....
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ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT
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Current Protocols in Nucleic Acid Chemistry
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Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid
PublikacjaThe series of 16 novel amino acid and peptide mycophenolic acid (MPA) derivatives was obtained as potential antibacterial agents. Coupling of MPA with respective amines was optimized with condensing reagents such as EDCI/DMAP and T3P/TEA. Amino acid analogs were received both as methyl esters and also with the free carboxylic group. The biological activity of the products was tested on five references bacterial strains: Klebsiella...
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Novel Cell Permeable Polymers of N-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids
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Branched-chain fatty acids affect the expression of fatty acid synthase and C-reactive protein genes in the hepatocyte cell line
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Application of the Harmonic Balance Method for Spatial Harmonic Interactions Analysis in Axial Flux PM Generators
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Journal of Arid Land
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Annals of Arid Zone
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Journal of Amino Acids
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Arid Land Geography
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Arid Zone Research
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JOURNAL OF ARID ENVIRONMENTS
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The physicochemical properties of 3D materials based on hyaluronic acid modified by tannic acid addition
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Influence of the Type of Amino Acid on the Permeability and Properties of Ibuprofenates of Isopropyl Amino Acid Esters
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New Analogues of Mycophenolic Acid
PublikacjaMycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. It is a non-competitive and reversible inhibitor of dehydrogenase inosine-5'-monophosphate (IMPDH). This compound belongs to the immunosuppressive drugs used for the prevention of both acute and chronic transplant rejection. Until now, two derivatives of MPA have been used clinically: mycophenolate mofetil (MMF,...
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PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY
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Amino acid formation by electron irradiation
PublikacjaW artykule zaprezentowano procedurę badania reakcji indukowanych przez niskoenergetyczne elektrony w mieszanych warstwach molekularnych CH3COOD:NH3.
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Modifications of total synthesis of mycophenolic acid
PublikacjaThe total synthesis of mycophenolic acid (MPA), a potent immunosuppressant, was modified. The obtained mycophenolic acid was suitable for further preparation of new prospective immunosuppressants with improved therapeutic properties.
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Updates in the Metabolism of Lactic Acid Bacteria
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Lysophosphatidic acid signaling in ovarian cancer
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Structural Analysis of 3,5-Bistrifluoromethylhydrocinnamic Acid
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Equilibrium and kinetic studies on acid dye Acid Red 88 adsorption by magnetic ZnFe2O4 spinel ferrite nanoparticles
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Ultrashort Cationic Lipopeptides–Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis
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Elicitation of solid callus cultures of Salvia miltiorrhiza Bunge with salicylic acid and a synthetic auxin (1-naphthaleneacetic acid)
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Harmonic Analysis Of Electrochemical and Corrosion Systems - A Review
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Corrosion monitoring by harmonic analysis in aqueous environments
PublikacjaThis paper presents tests concerning the rate of corrosion in non-alloy steel (type S235JR) in an aqueous environment, with an additive of sodium chloride by means of polarization resistance measurements and harmonic analysis. The tests have been carried out for steel samples exposed to the testing environment for six weeks, in order to obtain a constant rate of corrosion in the function of time. The measurements have aimed at...
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Fermionized Dipolar Bosons Trapped in a Harmonic Trap
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Application of harmonic techniques to evaluation of pitting corrosion
PublikacjaPrzedstawiono próbę zastosowania metod zmiennoprądowych do oceny podatności na korozję wżerową stali stopowych. Na sygnał stałoprądowy nałożono sinusoidę o częstotliwości 10 Hz. Dzięki jednoczesnej, cyfrowej rejestracji sygnału pobudzenia i odpowiedzi układu badanego otrzymano ciągłe zmiany modułu impedancji i modułu pojemności w trakcie klasycznej cyklicznej polaryzacji. Na podstawie jednego eksperymentu istnieje możliwość wyznaczenia...
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Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27)
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Adsorption Kinetics of Acid Dye Acid Red 88 onto Magnetic Multi‐Walled Carbon Nanotubes‐Fe3C Nanocomposite
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Microstructural behavior of water-in-oil emulsions stabilized by fatty acid esters of propylene glycol and zinc fatty acid salts
PublikacjaZbadano wpływ składu emulgatorów acylopropylenoglikolowych, modyfikowanych mydłami cynku, na charakter przemian strukturalnych jakim ulegają emulsje W/O stabilizowane przez takie emulgatory. Badano zarówno etap emulgowania jak i mikrostrukturę oraz właściwości reologiczne otrzymanych emulsji.
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Efficient Diethylzinc/Gallic Acid and Diethylzinc/Gallic Acid Ester Catalytic Systems for the Ring-Opening Polymerization of rac-Lactide
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Easy formation of acyl-Meldrum's acid anhydride
PublikacjaAcyl Meldrum's acid are usually a good source of ketenes upon definite thermal composition. However we treated acyl-Meldrum's acid with the Lewis acid and we observed formation of 5[[(2,2-dimethyl-4,6-dioxo-1,3-dioxan 5 ylidene)(acyl/arylamino)mathoxy](acyl/arylamino)methylene]-2,2dimethyl-1,3-dioxane-4,6 dione which means acyl-Meldrum's acid anhydride. The chemical properities of acyl-Meldrum's acid anhydride were explored.
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The 2:1 cocrystal of benzamide and pentafluororbenzoic acid
PublikacjaKrystaliczna struktura centrosymetrycznej supermolekuły składa się z czterech cząsteczek benzamidu oraz dwóch kwasu karboksylowego, które powiązane są ze sobą za pomocą wiązań wodorowych typu O-H...O oraz N-H...O.
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Phenazine - 2,6-dihydroxybenzoic acid (1/1)
PublikacjaOtrzymano krystaliczny kompleks fenazyny z kwasem 2,6-dihydroksybenzoesowym o stechiometrii 1:1. Badania struktury kompleksu za pomocą metod rentgenograficznych wykazały, że powiązane wiązaniami wodorowymi typu OH...N cząsteczki fenazyny układają się w stosy, które stabilizowane są poprzez oddziaływania typu π-π pierścieni aromatycznych. Cząsteczki kwasu zajmują przestrzenie kanałów tworzonych pomiędzy kolumnami pierścieni aromatycznych...
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ASCORBIC ACID IN POLYURETHANE SYSTEMS FOR TISSUE ENGINEERING
PublikacjaThe introduction of the paper was devoted to the main items of tissue engineering (TE) and the way of porous structure obtaining as scaffolds. Furthermore, the significant role of the scaffold design in TE was described. It was shown, that properly designed polyurethanes (PURs) find application in TE due to the proper physicochemical, mechanical and biological properties. Then the use of L-ascorbic acid (L-AA) in PUR systems for...