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Wyniki wyszukiwania dla: ROUTES OF INFECTION
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The Early Stages of Photosystem II Assembly Monitored by Measurements of Fluorescence Lifetime, Fluorescence Induction and Isoelectric Focusing of Chlorophyll-Proteins in Barley Etiochloroplasts
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Can mutations in the gene encoding transcription factor EKLF (Erythroid Krüppel-Like Factor) protect us against infectious and parasitic diseases?
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The induction of autophagy in human colon wt p53 and p53-null HCT116 cells by 4-methyl-1-nitroacridine derivative C-1748
PublikacjaPrzeprowadzone badania miały na celu określenie zdolności pochodnej 4-metylo-1-nitroakrydyny C-1748 do uruchomienia autofagii komórek ludzkiego raka okrężnicy HCT116 posiadających dziki gen p53 oraz podlinii nie posiadającej tego genu. Wszystkie eksperymenty przeprowadzone zostały przy stężeniu hamującym proliferację komórek nowotworowych w 90%. Wykazano, że indukowana przez C-1748 autofagia w komórkach raka okrężnicy jest zależna...
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Wykorzystanie modelu silnika indukcyjnego klatkowego do prądowej diagnostyki jego łożysk. Application of induction machine model for current diagnostics of bearings
PublikacjaW pracy podano widmo prądu stojana dla silnika normalnego oraz wprawianego w drgania o nastawianej częstotliwości. Drgania korpusu wirnika skutkują uginaniem się wirnika, co symuluje bicie wirnika od uszkodzenia łożysk. Podano też model matematyczny silnika, dopuszczający niecentryczność wirnika. Podano widmo prądu stojana przy pracy z wibracjami wirnika odwzorowującymi w pewnym przybliżeniu wibracje od uszkodzonych łożysk.
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Andrzej Chybicki dr inż.
OsobyZ wykształcenia informatyk, absolwent Wydziału Elektroniki, Telekomunikacji i Informatyki Politechniki Gdańskiej, doktor nauk technicznych w dziedzinie informatyka specjalizujący się w przetwarzaniau danych przestrzennych w rozproszonych systemach informatycznych. Ukierunkowany na wykorzystywanie osiągnięć i wiedzy zakresu prowadzonych badań w przemyśle. Współpracował z szeregiem podmiotów przemysłu informatycznego, geodezyjnego...
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Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values
PublikacjaWith the current massive increases in drug-resistant microbial infection as well as the significant role of fungal infections in the death toll of COVID-19, discovering new antifungals is extremely important. Natural and synthetic xanthones are promising derivatives, although only few reports have demonstrated their antifungal mechanism of action in detail. Newly synthetized by us xanthone derivative 44 exhibited strong antifungal...
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Interactions between hydration spheres of two different solutes in solution: The least squares fitting with constraints as a tool to determine water properties in ternary systems
PublikacjaBiological systems are complex and the problem of their description lies in mutual interactions between their components. This paper is focused on model experiment-based studies which can reduce these difficulties. The ternary aqueous N-methylacetamide (NMA)–Na2HPO4 system has been studied by means of the FTIR spectroscopy. A novel difference spectra method aimed to extract the spectral contribution of water affected simultaneously...
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Ochrona Przeciwkorozyjna Instalacji Przemysłowych i Risk Based Inspection (RBI)
Kursy OnlineRisk Based Inspection
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Effect of adopted rules of inference and methods of defuzzification on the final result of the evaluation of reliability made using the fuzzy logic methods
PublikacjaThe object of interest is to solve the problem of risk management of marine systems. But the main trouble is a lack of numerous and sure data on the reliability of the components of such systems. The methods based on the fuzzy logic seem to be helpful here. The goal of the article is to check the effect of using different fuzzy inference rules and methods of defuzzification on the final result of reliability assessment. The three...
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New model simulations of the global atmospheric electric circuit driven by thunderstorms and electrified shower clouds: The roles of lightning and sprites
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Excess production of phage λ delayed early proteins under conditions supporting high Escherichia coli growth rates
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Association of Higher Rates of Type 2 Diabetes (T2DM) Complications with Psychological and Demographic Variables: Results of a Cross-Sectional Study
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Exchange-traded products in Germany: development and substitution of exchange-traded funds, exchange-traded commodities and exchange-traded notes.
PublikacjaResearch background: Exchange-traded products (ETPs) are one of the most rapidly growing categories of financial products. Their fast development has been boosted by innovative features. Three main categories of ETPs are exchange-traded funds (ETFs), exchange-traded commodities (ETCs) and exchange-traded notes (ETNs). ETCs and ETNs remain least known, even though their number on some stock exchanges is high. In Europe, Germany...
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Wstępne wyniki badań dostępności sieci ASG-Eupos podczas inwentaryzacji trasy kolejowej Kościerzyna - Kartuzy = Preliminary research results of ASG-Eupos network availability during surveying of Kościerzyna-Kartuzyrailway route
PublikacjaW artykule przedstawiono wyniki pomiarów dostępności określonej wartości błędu współrzędnych, wyznaczonych przy wykorzystaniu sieci ASG-EUPOS, uzyskane podczas pomiarów inwentaryzacyjnych testowego odcinka linii kolejowej. Pomiary z wykorzystaniem4 odbiorników GNSS przeprowadzono w miesiącu lutym bieżącego roku na odcinku trasy kolejowej Kościerzyna - Kartuzy. Program badań zakładał montaż, na pokładzie platformy kolejowej napędzanej...
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Zakażenia bakteryjne w przewlekłym zapaleniu ucha środkowego - ocena przydatności diagnostyki molekularnej opartej o technikę PCR. Bacterial infection in chronic otitis media - assessment of usefulness of molecular diagnostic based in PCR method.
PublikacjaIdentyfikacja zakażeń w przewlekłym zapaleniu ucha środkowego jest trudna, o czym świadczą wysokie odsetki ujemnych wyników badań bakteriologicznych. Przyczyną tego jest trudność w uzyskiwaniu wiarygodnego materiału do badań oraz stosunkowo niska czułość klasycznych metod diagnostycznych. Amplifikacja bakteryjnego DNA techniką PCR jest badaniem, które może przyczynić się do zwiększenia efektywności i czułości badań bakteriologicznych....
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Five-phase squirrel-cage motor. Construction and drive properties
PublikacjaThis paper presents the simulation and experimental results of a five-phase squirrel-cage induction motor. The new machine has been designed to operate in a drive system with third harmonic rotor flux injection in order to improve the motor torque utilization. The motor structure, the mathematical model as well as the laboratory prototype have been described. The motor speed-torque characteristics and transients are elaborated...
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Effect of aeration of antibiotic-loaded bone cement on its properties and bactericidal effectiveness
PublikacjaBACKGROUND: Antibiotic-loaded bone cements are now widely used in medicine. They are able to locally deliver antibiotic particles and they allow treat or protect against infection. It is assumed that the bactericidal effectiveness of bioactive bone cements depend on the parameters of its production. Hence, the aim of this study was to check the effect of aeration of bone cement before mixing the components on its properties as...
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Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries
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Short-Term Outcomes of Percutaneous Trephination with a Platelet Rich Plasma Intrameniscal Injection for the Repair of Degenerative Meniscal Lesions. A Prospective, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study
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BMC INFECTIOUS DISEASES
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EMERGING INFECTIOUS DISEASES
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ACS Infectious Diseases
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LANCET INFECTIOUS DISEASES
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Repeated bouts of exhaustive exercise increase circulating cell free nuclear and mitochondrial DNA without development of tolerance in healthy men
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Notatki mikologiczne z okolic Ostrzyc (Kaszubski Park Krajobrazowy)= Mycological notes from the area of Ostrzyce (Kaszubski Landscape Park)
PublikacjaPrzeprowadzono wstępne badania mikobioty w okolicach Ostrzyc (Północna Polska, Pojerzerze Kaszubskie), podczas których natrafiono na interesujące macromycetes ujęte w poniższym wykazie. Stwierdzono łącznie 117 gatunków, siedem z nich (Strobilomyces strobilaceus, Geastrum fimbriatum, Hericium coralloides, Sparassis crispa, Matinus caninus, Clavariadelphus pistillaris i Polyporus Umbellatus) znajdują się pod ochroną ścisłą, a 23...
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Dissection of σE‐dependent cell lysis in Escherichia coli: roles of RpoE regulators RseA, RseB and periplasmic folding catalyst PpiD
PublikacjaTo understand the mechanism of sigma(E)-dependent cell lysis, we examined the consequences of deletion derivatives of rpoE regulators rseA, rseB and rseC on sigma(E) transcription, on levels of free versus membrane-bound sigma(E) and on OMP-biogenesis limiting factor(s) that could impact cell lysis. RT-PCR showed that individual nonpolar DeltarseA and DeltarseB increased the rpoE expression to varying extents, with pronounced induction...
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Phage Therapy—Challenges, Opportunities and Future Prospects
PublikacjaThe increasing drug resistance of bacteria to commonly used antibiotics creates the need to search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly. Phages that selectively infect and kill bacteria are often the only life-saving therapeutic option. Full legalization of this treatment method could help solve the problem of multidrug-resistant infectious diseases on a global scale. The aim of...
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ROLRES Wpływ tekstury i równości nawierzchni drogowych na straty energetyczne w oponach i zawieszeniach pojazdów samochodowych
ProjektyProjekt realizowany w Wydział Mechaniczny zgodnie z porozumieniem PBS1/A6/1/2012 z dnia 2012-12-04
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Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublikacjaPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
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Escherichia coli K-12 suppressor-free mutants lacking early glycosyltransferases and late acyltransferases. Minimal lipopolysaccharide structure and induction of envelope stress response.
PublikacjaTo elucidate the minimal lipopolysaccharide (LPS) structure needed for the viability of Escherichia coli, suppressor-free strains lacking either the 3-deoxy-d-manno-oct-2-ulosonic acid transferase waaA gene or derivatives of the heptosyltransferase I waaC deletion with lack of one or all late acyltransferases (lpxL/M/P) and/or various outer membrane biogenesis factors were constructed. Δ(waaC lpxL lpxM lpxP) and waaA mutants exhibited...
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Discussion on “Coupled effective stress analysis of insertion problems in geotechnics with the Particle Finite Element Method” by L. Monforte, M. Arroyo, J.M. Carbonell, and A. Gens
PublikacjaAddressed here is the Particle Finite Element Method (PFEM) modelling of undrained CPTu penetration with regard to a reference analytical solution based on the Spherical Cavity Expansion Method (SCEM). Also discussed is the choice of the soil model and its parameters. The effect of cone interface friction on CPTu simulation is analyzed in a series of penetration tests using Arbitrary Lagrangian-Eulerian (ALE) and Updated Lagrangian...
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Determination of volatile fatty acids in municipal wastewater and leachates from sewage sludge allotments and compost piles using direct aqueous injection gas chromatography preceded by distillation based sample cleanup
PublikacjaOpracowano metodykę i wykorzystano ją do oznaczania lotnych kwasów tłuszczowych w zanieczyszczonych próbkach wodnych,takich jak ścieki komunalne, odcieki ze składowiska osadów ściekowych i pryzm kompostu, stosując metodę bezpośredniego dozowania rzeczywistej próbki wodnej lub jej rektyfikatu do chromatografu gazowego.
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Biofilm formation and its regulation in Staphylococcus aureus
PublikacjaInfections caused by the major human and animal pathogen, Staphylococcus aureus are becoming an important problem due to its emerging resistance mechanisms and variety of virulence factors. Biofilm formation is considered to be one of the most important factor attributed to high pathogenicity of S. aureus. Described in the literature methods used in identification of biofilm forming abilities of bacteria consist of phenotypic and...
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Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere - Female, 64 - Cell image [4110730007991341]
Dane BadawczeThis is the histopathological image of CERVIX UTERI cell sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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The time-varying low-frequency magnetic-field emitted from the ship’s inverter-fed induction motor
Dane BadawczeThe dataset contains the magnetic field measurement results that are part of a comprehensive study on the assessment of the magnetic field emissions onboard of the research-training vessel. The measurements were carried out, nearby the bow thruster motor fed from the inverter, during maneuvering and the sea voyage. The bow thruster is assembled in the...
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Non-Destructive Assessment of Masonry Pillars using Ultrasonic Tomography
PublikacjaIn this paper, a condition assessment of masonry pillars is presented. Non-destructive tests were performed on an intact pillar as well as three pillars with internal inclusions in the form of a hole, a steel bar grouted by gypsum mortar, and a steel bar grouted by cement mortar. The inspection utilized ultrasonic stress waves and the reconstruction of the velocity distribution was performed by means of computed tomography. The...
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Small rov to detection and identification of dangerous underwater objects
PublikacjaA small unmanned underwater vehicle (UUV) to inspection of an undersea space is presented in the paper. Its behavior is controlled by a trained pilot. Correct detection and identification of targets depends on vehicle'sprecise displacement along a predefined route. Nowadays, the UUVs are equipped with an automatic control system to execute some basic maneuvers without constant human interventions. Hence, in the paper, an autopilot...
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Urinary excretion rates of 8-oxoGua and 8-oxodG and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns
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A five-year retrospective study shows increasing rates of antimicrobial drug resistance in Cabo Verde for both Staphylococcus aureus and Escherichia coli
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A five-year retrospective study shows increasing rates of antimicrobial drug resistance in Cabo Verde for both Staphylococcus aureus and Escherichia coli
PublikacjaObjectives Data on baseline drug resistance is important in informing future antimicrobial stewardship programs. So far, no data on the antimicrobial drug resistance of clinical isolates was available for the African archipelago of Cabo Verde. Methods We have performed a retrospective analysis over five-years (2013-17) of the antimicrombial drug susceptibility profiles of clinical isolates in the two main hospitals of Cabo Verde....
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Patient-Reported Quality of Life versus Physical Examination in Treating Temporomandibular Disorders with Intra-Articular Platelet-Rich Plasma Injections: An Open-Label Clinical Trial
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Relationship between left ventricular global longitudinal strain, infarct size and left ventricular function in patients with acute myocardial infarction in a stem cell therapy study
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Krzysztof Karwowski dr hab. inż.
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Agnieszka Witkowska dr hab. inż.
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Novel Nystatin A1 derivatives exhibiting low host cell toxicity and antifungal activity in an in vitro model of oral candidosis
PublikacjaOpportunistic oral infections caused by Candida albicans are frequent problems in immunocompromised patients. Management of such infections is limited due to the low number of antifungal drugs available, their relatively high toxicity and the emergence of antifungal resistance. Given these issues, our investigations have focused on novel derivatives of the antifungal antibiotic Nystatin A1, generated by modifications at the amino...
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Comparative analysis of mRNA transcripts of HT-29 cell line expressed in identical quantities for pathogenic E. coli strains UM146 and UM147 with control Escherichia coli Nissle 1917
PublikacjaAim of study was comparative analysis of mRNA transcripts of HT-29 cell line, expressed in identical quantities for the combination of pathogenic and non-pathogenic Escherichia coli strains. HT-29 confluent monolayers infection with two pathogenic E. coli strains UM146 and UM147 resulted in two sets of mRNA transcripts that were identical with RNA transcripts obtained for non-pathogenic one strain E. coli Nissle 1917. In this study...
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Metal nanoparticles-assisted early diagnosis of diseases
PublikacjaEarly diagnosis is essential for the effective illness treatment, but traditional diagnostic approaches inevitably have major downsides. Recent advancements in nanoparticle-based biosensors have created new opportunities for accelerating diagnosis. High surface area, exceptional sensitivity, high specificity, and optical characteristics of metal and metal oxide nanoparticles have made it possible to detect a variety of health conditions...
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MATHEMATICAL NOTES
Czasopisma -
Corporate tax rates (2000-2019) - Greece
Dane BadawczeOver the past twenty years, Greece has changed the statutory corporate tax rate, which in 2000 was 40%. The 2008 tax reform provided for a gradual reduction of the rate by 1% annually over the period 2010-2014 (from 25% to 20%). This dataset contains data on CIT rates in Greece.
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Number of statements issued about the intention to entrust the performance of work and the dynamics of change (%, year to year) in 2008-2018
Dane BadawczeWhen analyzing data on declarations of intention to entrust work to a foreigner, whose registration was completed at the end of 2017, with data on declarations on entrusting work to a foreigner, effective from 01/01/2018, it should noted that since 2018 the scope of data regarding statements. Currently they apply only to works that are not considered...