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Metody obliczeniowe w dynamice maszyn, Wykład, Mechatronika, Magisterskie, sem1, wiosna 23/24 (PG_00057022)
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Metody obliczeniowe w dynamice maszyn, W+P, Mechatronika/Mgr, sem.1, lato 21/22, (PG_00057022)
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Kinematyka i dynamika maszyn, Wykład, Mechanika i Budowa Maszyn, Inżynierskie, sem3, zima 23/24 (PG_00055380)
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Kinematyka i dynamika maszyn, Wykład, Mechatronika, Inżynierskie, sem3, zima 23/24 (PG_00055405)
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Processing of Polyester-Urethane Filament and Characterization of FFF 3D Printed Elastic Porous Structures with Potential in Cancellous Bone Tissue Engineering
PublicationThis paper addresses the potential of self-made polyester-urethane filament as a candidate for Fused Filament Fabrication (FFF)-based 3D printing (3DP) in medical applications. Since the industry does not provide many ready-made solutions of medical-grade polyurethane filaments, we undertook research aimed at presenting the process of thermoplastic polyurethane (TPU) filament formation, detailed characteristics, and 3DP of specially...
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Polyurethane based hybrid ciprofloxacin-releasing wound dressings designed for skin engineering purpose
PublicationPurpose Even in the 21st century, chronic wounds still pose a major challenge due to potentially inappropriate treatment options, so the latest wound dressings are hybrid systems that enable clinical management, such as a hybrid of hydrogels, antibiotics and polymers. These wound dressings are mainly used for chronic and complex wounds, which can easily be infected by bacteria. Materials and methods Six Composite Porous Matrices...
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Composite Polyurethane-Polylactide (PUR/PLA) Flexible Filaments for 3D Fused Filament Fabrication (FFF) of Antibacterial Wound Dressings for Skin Regeneration
Publicationhis paper addresses the potential application of flexible thermoplastic polyurethane (TPU) and poly(lactic acid) (PLA) compositions as a material for the production of antibacterial wound dressings using the Fused Filament Fabrication (FFF) 3D printing method. On the market, there are medical-grade polyurethane filaments available, but few of them have properties required for the fabrication of wound dressings, such as flexibility...
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9,9′-bifluorenylidene derivatives as novel hole-transporting materials for potential photovoltaic applications
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Tailor-Made Polysaccharides for Biomedical Applications
PublicationPolysaccharides (PSAs) are carbohydrate-based macromolecules widely used in the biomedical field, either in their pure form or in blends/nanocomposites with other materials. The relationship between structure, properties, and functions has inspired scientists to design multifunctional PSAs for various biomedical applications by incorporating unique molecular structures and targeted bulk properties. Multiple strategies, such as...
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Dynamics of Oxidative Damage at Early Stages of Estrogen-dependant Carcinogenesis
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Ambulatory blood pressure and long-term risk for atrial fibrillation
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A comprehensive evaluation of flexible FDM/FFF 3D printing filament as a potential material in medical application
PublicationThe use of FDM/FFF in 3D printing for medical sciences is becoming common. This is due to the high availability and decent price of both 3D printers and filaments useful for FDM/FFF. Currently, researchers' attention is focused mainly on the study of medical filaments based on PLA, PCL or their modifications. This contributes to insufficient diversity of medical-grade filaments on the market. Moreover, due to the lack of specified...
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Biomedical engineering of polysaccharide-based tissue adhesives: Recent advances and future direction
PublicationTissue adhesives have been widely used for preventing wound leaks, sever bleeding, as well as for enhancing drug delivery and biosensing. However, only a few among suggested platforms cover the circumstances required for high-adhesion strength and biocompatibility, without toxicity. Antibacterial properties, controllable degradation, encapsulation capacity, detectability by image-guided procedures and affordable price are also...
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Antibacterial Porous Systems Based on Polylactide Loaded with Amikacin
PublicationThree porous matrices based on poly(lactic acid) are proposed herein for the controlled release of amikacin. The materials were fabricated by the method of spraying a surface liquid. Description is given as to the possibility of employing a modifier, such as a silica nanocarrier, for prolonging the release of amikacin, in addition to using chitosan to improve the properties of the materials, e.g., stability and sorption capacity....
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Molecular modelling of membrane sterols with the use of the GROMOS 96 forcefield
PublicationPodstawowym zadaniem tego projektu było udowodnienie zasadności stosowania pola siłowego GROMOS 96 do symulacji steroli błonowych metodą dynamiki molekularnej. Uzyskane wyniki jasno wskazują, że to pole siłowe bardzo dobrze nadaje się do symulacji silnie lipofilowych układów.
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Structural and dynamic insights on the EmrE protein with TPP+ and related substrates through molecular dynamics simulations
PublicationEmrE is a bacterial transporter protein that forms an anti-parallel homodimer with four transmembrane helices in each monomer. EmrE transports positively charged aromatic compounds, such as TPP+ and its derivatives. We performed molecular dynamics (MD) simulations of EmrE in complex with TPP+, MeTPP+, and MBTPP+ embedded in a membrane. The detailed molecular properties and interactions were analysed for all EmrE-ligand complexes....
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Scale-consistent approach to the derivation of coarse-grained force fields for simulating structure, dynamics, and thermodynamics of biopolymers
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Design and synthesis of new substrates of HtrA2 protease
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Oxylipin profiling for clinical research: Current status and future perspectives
PublicationOxylipins are potent lipid mediators with increasing interest in clinical research. They are usually measured in systemic circulation and can provide a wealth of information regarding key biological processes such as inflammation, vascular tone, or blood coagulation. Although procedures still require harmonization to generate comparable oxylipin datasets, performing comprehensive profiling of circulating oxylipins in large studies...
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Modeling the Structure, Dynamics, and Transformations of Proteins with the UNRES Force Field
PublicationThe physics-based united-residue (UNRES) model of proteins ( www.unres.pl ) has been designed to carry out large-scale simulations of protein folding. The force field has been derived and parameterized based on the principles of statistical-mechanics, which makes it independent of structural databases and applicable to treat nonstandard situations such as, proteins that contain D-amino-acid residues. Powered by Langevin dynamics...
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Methodology of Selecting the Optimal Receptor to Create an Electrochemical Immunosensor for Equine Arteritis Virus Protein Detection
PublicationThe study reports a methodology of selecting the optimal receptor to create an electrochemical immunosensor for equine arteritis virus (EAV) protein detection. The detection was based on antigen recognition by antibodies immobilized on gold electrodes. Modification steps were controlled by electrochemical impedance spectroscopy and cyclic voltammetry measurements. In order to obtain the impedance immunosensor with the best parameters,...
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Analysis of the Link between the Redox State and Enzymatic Activity of the HtrA (DegP) Protein from Escherichia coli
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Eco-friendly modification of bitumen: The effects of rubber wastes and castor oil on the microstructure, processability and properties
PublicationThe bitumen industry in the European Union is facing several difficulties, including rising demand, unstable oil supply, rising prices for synthetic polymer modifiers, and a focus on lowering carbon footprint. Bitumen modification with crumb rubber (CR) is one of the most promising solution to these challenges. However, CR-modified bitumen have poor processability and low storage stability. To overcome these flaws we are introducing...
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Katedra Technologii Koloidów i Lipidów
Research TeamsAktywność badawcza Katedry Technologii Koloidów i Lipidów obejmuje szeroki zakres tematyczny z obszaru nauk o koloidach, lipidach i zjawiskach międzyfazowych. Badania prowadzone są w celu charakteryzowania fundamentalnych oddziaływań różnych układów koloidalnych z organizmem ludzkim oraz potencjalnego wykorzystania wyników pracy eksperymentalnej w projektowaniu nowych struktur koloidalnych o zwiększonej funkcjonalności w określonych...
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Mechatronics and mechanism theory
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Extension of the Unres Package for Physics-Based Coarse-Grained Simulations of Proteins and Protein Complexes to Very Large Systems
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Mechanika ciała stałego i płynów I , W/C, IM, sem.03, zimowy 22/23 (PG_00039790)
e-Learning CoursesZaprezentowane zostaną treści obejmujące statykę i kinematykę punktu, bryły, układów punktów i układów brył
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Mechanika ciała stałego i płynów II, W, Inż. Materiałowa, sem4, lato 21/22 (PG_00039796)
e-Learning CoursesZapoznanie studentów z podstawowymi prawami kinematyki i dynamiki ciała stałego i mechaniki płynóworaz ukształtowanie umiejętności rozwiązywania zadań praktycznych, w zakresie zagadnień dynamiki ciałastałego i mechaniki płynów
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Kinematyka i dynamika maszyn, Wykład, Mechatronika, Inżynierskie, sem3, zima 22/23 (PG_00055405)
e-Learning CoursesZapoznanie studenta z najważniejszymi pojęciami teorii mechanizmów i maszyn. Przeglądu rodzajów mechanizmów. Wprowadzenie pojęć analizy strukturalnej. Prezentacja wybranych metod wyznaczania położeń, prędkości i przyspieszeń. Prezentacja metod dynamiki mechanizmów. Wprowadzenie do zagadnień drgań swobodnych i wymuszonych układów dyskretnych.
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Mechanika ciała stałego i płynów II W, Inż. Materiałowa, sem4, lato 22/23 (PG_00039796)
e-Learning CoursesPrzedmiot służy zapoznaniu studentów z podstawowymi prawami kinematyki i dynamiki ciała stałego i mechaniki płynów oraz kształci umiejętności rozwiązywania zadań praktycznych, w zakresie zagadnień dynamiki ciała stałego i mechaniki płynów
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Adiponectin is unrelated to kidney function or injury markers in renal transplant recipients: A one-year follow-up study
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Biomateriały polimerowe
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Biomateriały polimerowe
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Performance of protein-structure predictions with the physics-based UNRES force field in CASP11
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Improved Consensus-Fragment Selection in Template-Assisted Prediction of Protein Structures with the UNRES Force Field in CASP13
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Evaluation of the scale-consistent UNRES force field in template-free prediction of protein structures in the CASP13 experiment
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Selection of Effective HTRA3 Activators Using Combinatorial Chemistry
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Multibo_2017 Project-based software environment for scientists in multibody dynamics
ProjectsProject realized in Department of Mechanics and Mechatronics
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Fruit seeds oils as a cosmetic emulsions component
PublicationThe fruit seeds are known to have a considerable amount of oil and their potential specialty as nutraceutical oil was suggested based on high level of unsaturated triacyglycerols (major fatty acids are linoleic, linolenic, oleic) and a high content of tocols (tocopherols and tocotrienols). In this study the possibility of application fruit seeds oils in W/O and O/W emulsion systems was investigated to find the influence of the...
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The possibility of use by-products for synthesis of emulsifiers
PublicationIn the last years the interest in use of materials originated from natural sources, e.g. vegetables to produce attractive products still grows. According to that, also the synthesis of these products should be adequate to the green chemistry requirements. The typical example observed in recent years focuses on utlization of bioglycerol - the by - product of global biodiesel manufacturing. The still growing production of biodiesel...
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Virgin rapeseed oils obtained from different rape varieties by cold pressed method - their characteristics, properties, and differences
PublicationCelem pracy było porównanie olejów uzyskanych z różnych odmian rzepaku. Oznaczono skład kwasów tłuszczowych, wartości liczb charakterystycznych (AcV, AnV, PV, TOTOX), zawartość karotenów, tokoferoli, chlorofili, polifenoli, metali (żelazo i miedź). Oznaczono stabilność oksydatywną olejów tłoczonych na zimno. Oznaczono skład frakcji lotnej i przeprowadzono analizy sensoryczne.
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Comparison of oil yield and quality obtained by different extraction procedures from salmon (Salmo salar) processing byproducts
PublicationThe content and composition of lipids in different byproducts (skins, heads, and backbones) from mechanically processed farmed Atlantic salmon were determined and compared with that obtained from wild salmon. Three different procedures were used to establish the optimal conditions of oil extraction (at high temperature −95°C, “cold” extraction at temperature not exceeding 15°C and enzyme assisted with Alcalase). “Cold” extraction...
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Influence of cabbage juices on oxidative changes of rapeseed oil and lard
PublicationCelem badań było określenie wpływu soków wyizolowanych z kapusty surowej i kiszonej na przemiany oksydatywne i termooksydatywne tłuszczów roślinnych (na przykładzie oleju rzepakowego podwójnie ulepszonego) i zwierzęcych (na przykładzie smalcu). Tłuszcze te ogrzewano w temperaturze 100 0C z sokami z kapusty w układzie modelowym przez 6 godzin, pobierając co 1,5 godz. próbki do badań.Po procesie ogrzewania tłuszczów w obecnosci soków...
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The influence of the UV irradiation on degradation of virgin rapeseed oils
PublicationThis paper presents research which is a continuation of the investigations described earlier. The aim of these studies was to determine the influence of UV irradiation on flavor and the oxidative stability of different rapeseed oils varieties. For the purpose of this study, oil samples underwent accelerated deterioration for 4.5 h under a UV light test. In the obtained sample, characteristic values (peroxide (PV, 1.23–1.62 meq...
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Photoinduced and thermal oxidation of rapeseed and sunflower oils
PublicationCelem prezentowanych badań było porównanie stabilności oksydatywnej olejów rzepakowych i słonecznikowych. Na etapie przyspieszania utleniania zastosowano promieniowanie UV. Po naświetlaniu lotne produkty utlenienia były izolowane z fazy nadpowierzchniowej przy pomocy mikroekstrakcji do fazy stacjonarnej HS-SPME(włókno DVB/CAR/PDMS) i oznaczane z zastosowaniem chromatografii gazowej z detektorem płomieniowo-jonizacyjnym (GC/FID)....
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Molecular Characterisation of Uterine Endometrial Proteins during Early Stages of Pregnancy in Pigs by MALDI TOF/TOF
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Highly selective impedimetric determination of Haemophilus influenzae protein D using maze-like boron-doped carbon nanowall electrodes
PublicationThis study reports a novel impedimetric immunosensor for protein D detection in purified and bacterial (Haemophilus influenzae, Hi) samples. The detection was based on antigen recognition by anti-protein D antibodies (apD) immobilised at the maze-like boron-doped carbon nanowall electrodes (B:CNW). The B:CNW electrodes were synthesised, and their surface was characterised by scanning electron microscopy (SEM) and X-ray photoelectron...
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Biopolymer-based composites for tissue engineering applications: A basis for future opportunities
PublicationBiomimetic scaffolds supporting tissue regeneration are complex materials with multifunctional characteristics. The unique biocompatibility and biodegradability of biopolymers make them excellent candidates for tissue engineering and regenerative medicine. Biopolymers, which have a wide range of properties, can be obtained from different natural sources. Depending on the target tissue, biopolymers can be engineered to meet a series...
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Modeling protein structures with the coarse-grained UNRES force field in the CASP14 experiment
PublicationThe UNited RESidue (UNRES) force field was tested in the 14th Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP14), in which larger oligomeric and multimeric targets were present compared to previous editions. Three prediction modes were tested (i) ab initio (the UNRES group), (ii) contact-assisted (the UNRES- contact group), and (iii) template-assisted (the UNRES-template...
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2018 Practice Guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension
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