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Search results for: psychosomatic medicine
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Automated Reasoning Based User Interface
PublicationMotivation: The ability to directly trace how requirements are implemented in a software system is crucial in domains that require a high level of trust (e.g. medicine, law, crisis management). This paper describes an approach that allows a high level of traceability to be achieved with model-driven engineering supported by automated reasoning. The paper gives an introduction to the novel, automated user interface synthesis in...
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Exploring the landscape of automatic cerebral microbleed detection: A comprehensive review of algorithms, current trends, and future challenges
PublicationThis paper provides the first review to date which gathers, describes, and assesses, to the best of our knowledge, all available publications on automating cerebral microbleed (CMB) detection. It provides insights into the current state of the art and highlights the challenges and opportunities in this topic. By incorporating the best practices identified in this review, we established guidelines for the development of CMB detection...
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Molecular Design Using Selected Concentration Effects in Optically Activated Fluorescent Matrices
PublicationMolecular physics plays a pivotal role in various fields, including medicine, pharmaceuticals, and broader industrial applications. This study aims to enhance the methods for producing specific optically active materials with distinct spectroscopic properties at the molecular level, which are crucial for these sectors, while prioritizing human safety in both production and application. Forensic science, a significant socio-economic...
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Bioreactor shoot cultures of Rhododendron tomentosum (Ledum palustre) for a large-scale production of bioactive volatile compounds
PublicationRhododendron tomentosum Harmaja (Ledum palustre), a peat bog plant from Ericaceae family, has been used in traditional medicine as the anti-arthritis agent. Although modern researches confirm its anti-inflammatory properties, it remains threatened by habitat degradation and possibilities to collect this endangered species from its natural environment for further biological activity studies are limited. Therefore, R. tomentosum...
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Polysaccharide-based Nanocomposites for Biomedical Applications: A Critical Review
PublicationPolysaccharides (PSA) are taking specific position among biomaterials for advanced applications in medicine. Nevertheless, poor mechanical properties is known as the main drawback of PSA, which highlights need for PSA modification. Nanocomposites PSA (NPSA) are a class of biomaterials widely used as biomedical platforms, but despite their importance and worldwide use have not been reviewed. Herein we critically reviewed application...
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Robust and Efficient Machine Learning Algorithms for Visual Recognition
PublicationIn visual recognition, the task is to identify and localize all objects of interest in the input image. With the ubiquitous presence of visual data in modern days, the role of object recognition algorithms is becoming more significant than ever and ranges from autonomous driving to computer-aided diagnosis in medicine. Current models for visual recognition are dominated by models based on Convolutional Neural Networks (CNNs), which...
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Chitosan-based inks for 3D printing and bioprinting
PublicationThe advent of 3D-printing/additive manufacturing in biomedical engineering field has introduced great potential for the preparation of 3D structures that can mimic native tissues. This technology has accelerated the progress in numerous areas of regenerative medicine, especially led to a big wave of biomimetic functional scaffold developments for tissue engineering demands. In recent years, the introduction of smart bio-inks has...
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Establishing the allosteric mechanism in CRISPR‐Cas9
PublicationAllostery is a fundamental property of proteins, which regulates biochemical information transfer between spatially distant sites. Here, we report on the critical role of molecular dynamics (MD) simulations in discovering the mechanism of allosteric communication within CRISPR‐Cas9, a leading genome editing machinery with enormous promises for medicine and biotechnology. MD revealed how allostery intervenes during at least three...
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Validation of Hydraulic Mechanism during Blowout Trauma of Human Orbit Depending on the Method of Load Application
PublicationThe more we know about mechanisms of the human orbital blowout type of trauma, the better we will be able to prevent them in the future. As long as the buckling mechanism’s veracity is not in doubt, the hydraulic mechanism is not based on equally strong premises. To investigate the correctness of the hydraulic mechanism’s theory, two different methods of implementation of the hydraulic load to the finite element method (FEM) model...
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Validated HPTLC method for determination of ledol and alloaromadendrene in the essential oil fractions of Rhododendron tomentosum plants and in vitro cultures and bioautography for their activity screening
PublicationRhododendron tomentosum (Ledum palustre) is a bog shrub used in traditional medicine for treatment of respiratory and rheumatic diseases. Due to the large variability of the chemical composition of its essential oil, depending on the habitat, the in vitro cultures were established as the alternative source of the volatile fraction. There is a need to monitor a quality of the field grown as well as in vitro plant material, especially...
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Modernisation of existing hospitals
PublicationProgress in medicine and development of medical technologies directly affect the evolution of methods for treating patients in hospitals. The main task of 19th-century hospitals was patient care and nursing, while the aim of hospitals today is to diagnose and treat patients effectively in the shortest time possible. The changes which are taking place in methods of treatment affect the functional-spatial layout of hospitals. This...
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Sustainable polymers targeted at the surgical and otolaryngological applications: Circularity and future
PublicationThe ongoing climate changes, high air and noise pollution have significant impact on humans’ health. This influence is especially visible in otolaryngology, which focuses on respiratory and hearing systems disfunctions. However, even though surgeries are done in response to diseases related to climate changes, they also have a negative impact on the environment, mostly connected with the inherence of single-use fossil fuel derived...
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Kobieta ciężarna i alkohol-toksyczny związek. Smółka noworodków jako materiał w diagnostyce spożywania alkoholu w czasie ciąży
PublicationKażda ilość alkoholu spożyta przez ciężarną kobietę może spowodować poronienie, przedwczesny poród, patologię łożyska, zahamowanie wzrostu wewnątrzmacicznego płodu i wystąpienie licznych wad wrodzonych wywołanych alkoholem, określanych wspólnie mianem spektrum płodowych zaburzeń alkoholowych - FASD. Mogą one objawiać się zaburzeniami psychicznymi i/lub fizycznymi. Współczesna diagnostyka u noworodków zespołu FASD opiera się najczęściej...
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A new OSS design based on parameter sensitivity tochanges in measurements
PublicationW wyniku istniejących silnych ograniczeń praktycznych i etycznych nałożonych na eksperymenty medyczne, procedura estymacji parametrów w diagnozie i terapii jest często zagadnieniem skomplikowanym. Jeśli dane pomiarowe pobierane są w postaci próbek krwi, liczba tych próbek, a także czas obserwacji powinny być zminimalizowane. Optymalizacja eksperymentu polega na optymalizacji odpowiedniego sformułowanego kryterium będącego funkcją...
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Recent breakthroughs in the stability testing of pharmaceutical compounds
PublicationPharmaceutical development is mostly focused on the research leading to approval of a new and viable active substance. However, there is a number of old generation compounds that are still being used in contemporary medicinal practice. So that new analytical developments should cover not only the safety of newly developed drug substances, which is obvious, but should also be directed into the search of individual stability issues...
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Laserowa modyfikacja treści i nanonieporozumienia drukowane w 3D
PublicationW obliczu wielkich wyzwań naukowych zapomina się czasem o drobnych niedopowiedzeniach, które mogą zaważyć na wyniku całego badania. Szeroka współpraca, zwłaszcza interdyscyplinarna, jest niezbędna do osiągnięcia sukcesu, ale bywa również przyczyną powstawania nieporozumień i formułowania błędnych założeń technicznych. Nadużywanie modnych słów kluczowych może doprowadzić do szeregu nieporozumień i wyciągania fałszywych wniosków...
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Metropolie ery cyfrowej- wpływ nowych technologii informacyjnych i komunikacyjnych na kształt współczesnego miasta = Digital metropolis - the impact of new information and communication technologies on contemporary city
PublicationDynamiczny rozwój technologii informacyjnych i cyfrowych zapoczątkowany w drugiej połowie XX wieku wpłynął na zmianę wizerunku współczesnego miasta. Coraz bardziej wyraźną rolę w jego tworzeniu zaczęły odgrywać fasady, powłoki budynków oraz fragmenty przestrzeni publicznych, w obrębie których zaczęto integrować pojawiające się innowacyjne technologie, potocznie zwane medialnymi. Powierzchnie architektoniczne wyposażone w nie...
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A nontargeted approach to determine the authenticity of Ginkgo biloba L. plant materials and dried leaf extracts by liquid chromatography-high-resolution mass spectrometry (LC-HRMS) and chemometrics
PublicationThe lack of stringent regulations regarding raw materials for herbal supplements used for medicinal purposes has been a constant challenge in the industry. Ginkgo biloba L. leaf extracts attract consumers because of the supposed positive effect on mental performance and memory. Supplements are produced using dried leaf materials and standardized leaf extracts such as EGb 761. Adulteration of Ginkgo biloba L. plants and extracts...
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Phosphoroorganic Metal Complexes in Therapeutics
PublicationThe present mini-review highlights recent developments on antitumor activity of metal-based therapeutics which have been a subject of researches for the last few decades. In 1965, Rosenberg found that during an electrolysis on platinum electrodes a complex of Pt is generated which inhibited to a great extent a binary fission in Escherichia coli bacteria. This discovery started a new chapter in medicinal chemistry and the interesting...
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Investigation of antifungal and antibacterial potential of green extracts of propolis
PublicationPropolis extracts have been used in traditional medicines since ages due to its advantageous complex chemical composition. However, the antibacterial and antifungal activity of poplar propolis extracts prepared in Natural Deep Eutectic Solvent (NADES) are seldom studied. This study investigates suitable alternate for ethanol as a solvent for extraction for Polish poplar propolis. It also attempts to identify suitable extraction...
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Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)
PublicationA healthy ageing process is important when it is considered that one-third of the population of Europe is already over 50 years old, although there are regional variations. This proportion is likely to increase in the future, and maintenance of vitality at an older age is not only an important measure of the quality of life but also key to participation and productivity. So, the binomial “nutrition and ageing” has different aspects...
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Evaluation of antimicrobial activities of powdered cuttlebone against Klebsiella oxytoca, Staphylococcus aureus, and Aspergillus flavus
PublicationBackground: The presence of medicines in the environment is considered as a serious threat to the human health. The entrance of these substances into the water sources causes soil pollution, which eventually leads to the environmental pollution and it creates some problems for the public health. Also, increasing antibiotic resistant bacteria has attracted the attention of researchers to the use of natural resources such as marine...
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Support for research biobanks among medical students in the Republic of Kazakhstan
PublicationBackground: Over the past few years, several biobanks have been organized in the Republic of Kazakhstan (RoK). As research biobanks are becoming an increasingly important tool for precision medicine, they require competent biobankers who will help disseminate the idea of biobanking throughout the society and support donation for research purposes. This study aimed to assess the support for research...
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Edible black ant Smith (Carebara vidua) as human food – A systematic review
PublicationMeeting food security is one of the major global challenges to ensure sufficient supply of food for current and future generations, considering increasing population growth and climate change issues. Consequently, the consumption of edible insects as an alternative food source has recently gained global attention for combating global food insecurity. The present review aims to provide information on the recent progress in consumption...
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Evaluation of the content of inorganic anions in tree saps
PublicationTree saps were once commonly used in the countries of Northern, Central and Eastern Europe. Although once almost forgotten, their popularity has been growing recently as part of an interest in organic food and traditional medicine. Tree saps, tapped mainly from birch and maple trees, are drunk both fresh and fermented or are used as raw material for the production of food products, e.g. syrups. The aim of this study was to determine...
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PSYCHOMETRIC PROPERTIES OF THE POLISH VERSION OF THE GENERALIZED ANXIETY DISORDER 7-ITEM SCALE (GAD-7) IN A NON-CLINICAL SAMPLE OF EMPLOYEES DURING PANDEMIC CRISIS
PublicationObjectives: The COVID-19 outbreak is an example of a crisis that triggered an increase in generalized anxiety disorder. The study aims to validate the Polish version of the Generalized Anxiety Disorder 7-item scale (GAD-7) by Spitzer et al. among a non-clinical sample of employees and examine the invariance depending on the gender and age of working adults. Material and Methods: For assessing factor structure of the Polish version...
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Essential Oils, Silver Nanoparticles and Propolis as Alternative Agents Against Fluconazole Resistant Candida albicans, Candida glabrata and Candida krusei Clinical Isolates
PublicationDevelopment of effective and safe therapeutic treatment of fungal infections remains one of the major challenge for modern medicine. The aim of presented investigation was to analyze the in vitro antifungal activity of selected essential oils, ethanolic extracts of propolis and silver nanoparticles dropped on TiO2 against azole-resistant C. albicans (n = 20), C. glabrata (n = 14) and C. krusei (n = 10) clinical isolates. Among...
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LC–MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes
PublicationGalanga (Alpinia officinarum Hance) is a pungent and aromatic rhizome, which is a member of the ginger family (Zingiberaceae). The rhizomes of this plant have been used as a traditional medicine in far east countries for relieving stomach ache, invigorating the circulatory system, treating colds, and reducing swelling. The aim of this study was to investigate antioxidant and anticholinergic properties of galanga. For this purpose,...
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Piezoelectric Transducer for Mechanical Assessment of Soft Tissues. Concept, Implementation and Analysis
PublicationThe main goal of this work was following: preparation of a new concept, implementation and analysis of the piezoelectric resonant sensor/actuator for measuring the aging process of human skin. The research work has been carried out in the framework of cooperation between the INP-ENSEEIHT-LAPLACE, Toulouse, France, and at the Gdansk University of Technology, Faculty of Electrical and Control Engineering, Research Group of...
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Bioactive polyurethanes applied as a surgical implants
PublicationSynthetic materials are applied in many branches of the industry, i.a. in medicine as a casing of apparatus, elements of artificial organs (hearts, blood vessels), catheters, wound healings, intra aortic balloons, mammary implants to mention but a few. Polymeric material used in such applications must be distinguished by a good biocompatybility. Since many years extensive research are employed to develop a new polymers that can...
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Influence of laser melting on surface layer properties of titanium alloy Ti6Al4V
PublicationIn time of rapid technology and medicine progress, implants are becoming more widely used in the human body, ranging from dental implants, stabilizing plates, screws, orthopaedic prostheses. For example, there are many types of hip prostheses used for hip replacement as well as various types of materials used for these orthopaedic prostheses. Properties of titanium alloys used in hip prostheses combined with good strength properties,...
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Influence of several biodegradable components added to pure and nanosilver-doped PMMA bone cements on its biological and mechanical properties
PublicationAcrylic bone cements (BC) are wildly used in medicine. Despite favorable mechanical properties, processability and inject capability, BC lack bioactivity. To overcome this, we investigated the effects of selected biodegradable additives to create a partially-degradable BC and also we evaluated its combination with nanosilver (AgNp). We hypothesized that using above strategies it would be possible to obtain bioactive BC. The Cemex...
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Właściwości fizykochemiczne i możliwości zastosowania preparatu biosurfaktantowego wytwarzanego przez Pseudomonas PS-17
PublicationPraca dotyczy właściwości fizykochemicznych nieoczyszczonego biosurfaktantu wytwarzanego przez szczep Pseudomonas PS-17 (biokompleksu ramnolipidowego RL53) oraz możliwości jego zastosowania w rafinacji olejów roślinnych. W części literaturowej przedstawiono zarys wiedzy na temat toksyczności i biodegradowalności biosurfaktantów, a także na temat wybranych właściwości fizykochemicznych tych związków, takich jak zdolność do micelizacji...
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Assessment of the physical fitness of road cyclists in the step and ramp protocols of the incremental test
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Interaction of selected drugs with food in the group of patients over 60 years of age
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Distribution of plantar pressure during jogging barefoot or in minimalistic shoes in people who used to run in cushioned shoes
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Ryzyko statystyczne a ryzyko rzeczywistego pacjenta = Statistical risk and risk of the real patient
PublicationDzięki wieloletnim obserwacjom populacji ludzkiej udało się zidentyfikować czynniki ryzyka choroby wieńcowej. Najważniejsze z nich to: wiek, płeć, obciążenie genetyczne, palenie papierosów, stężenie cholesterolu we krwi, ciśnienie tętnicze, brak aktywności fizycznej, nadwaga, obecność cukrzycy. Obserwacje prospektywne populacji dostarczyły danych do opracowania modeli, które określają relacje między wartościami czynników ryzyka...
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The impact of resistance exercise range of motion on the magnitude of upper-body post-activation performance enhancement
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Does caffeine ingestion affect the lower-body post-activation performance enhancement in female volleyball players?
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Antagonist activation exercises elicit similar post-activation performance enhancement as agonist activities on throwing performance
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Parasomnias and obstructive sleep apnea syndrome: in search for a parasomnia evaluating tool appropriate for OSAS screening
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Species differences in total mercury concentration in gulls from the Gulf of Gdansk (Southern Baltic)
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The analysis of the empathy factor in students of medical sciences
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Room temperature solvent extraction for simple and fast determination of total concentration of Ca, Cu, Fe, Mg, Mn, and Zn in bee pollen by FAAS along with assessment of the bioaccessible fraction of these elements using in vitro gastrointestinal digestion
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Badania przesiewowe w kierunku depresji w wybranej dorosłej poulacji wiejskiej - doniesienie wstępne = Screening for depression in adult rural population-preliminary study
PublicationZe względu na częste występowanie zaburzeń depresyjnychoraz ich współistnienie z chorobami somatycznymi i niekorzystny wpływ na przebieg leczenia podkreśla się wagę badań przesiewowych których głównym celem jest zarówno dokonanie szybkiej, wstępnej diagnozy, jak i ocena częstości występowania danego zaburzenia.
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Wrodzone zwężenie zastawki aortalnej - wyniki leczenia operacyjnego i interwencyjnego, z wykluczeniem krytycznej stenozy aortalnej noworodkowej = Congenitial aortic stenosis - outcomes after surgical treatment and baloon dilatation with exclusion of neonatal critical congenitial aortic stenosis
PublicationOdległe wyniki leczenia wrodzonego zwężenia zastawki aortalnej są ważnym problemem medycznym. Celem pracy była ocena wyników postępowania zabiegowego u dzieci z wrodzonym zwężeniem zastawki aortalnej.
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Znajomość własnego ciśnienia tętniczego i rozpowszechnienie nadciśnienia tętniczego w populacji wiejskiej - Program Kiełpino = The cognizance of patient's own blood pressure values and the hypertension prevalence among rural population - Kiełpino program
PublicationNadciśnienie tętnicze jest jedną z najczęstszych chorób przewlekłych występujących w Polsce. Nieleczone nadciśnienie tętnicze prowadzi do licznych powikłań, jest przyczyna przedwczesnej umieralności, wpływa na pogorszenie komfortu życia pacjenta i zwiększa koszty leczenia. Ocena znajomości własnego ciśnienia tętniczego krwi oraz rozpowszechnienia nadciśnienia tętniczego u pacjentów w wiejskiej praktyce lekarza rodzinnego - jest...
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Świadomość posiadania nadwagi pierwszym krokiem w zapobieganiu otyłości i jej powikłaniom = Awaraness of being overweight is the first step to avoid obesity and its complications
Publicationw ostatnim dwudziestoleciu obserwuje się niepokojący wzrost występowania nadwagi i otyłości na całym świecie. Istotnym elementem profilaktyki zapobiegajacej dalszemu nadmiernemu rozpowszechnieniu nadwagi i otyłości jest uświadomienie osobom najbardziej zagrożonym posiadania tych zaburzeń. Niniejsza praca ma na celu ocenę świadomości mieszkańców wsi na temat nadwagi
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Rodzinny katecholaminergiczny częstoskórcz komorowy = Familial catecholaminergic Polymorphic Ventricular Tachycardia
PublicationCelem pracy jest przedstawienie katecholaminergicznego wielokształtnego częstoskurczu komorowego. Wielokształtny rodzinny katecholaminozależny częstoskórcz komorowy jest sporadycznie występującą arytmią komorową. W rodzinnej postaci PVT wskazana jest implantacja kardiowertera-defibrylatora celem prewencji nagłej śmierci sercowej oraz rozszerzona diagnostyka genetyczna.
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Rozpowszechnienie nadwagi i otyłości w populacji wiejskiej - Program ''Kiełpino'' = Prevalence of overweight and obesity in village population - ''Kiełpino Trial''
PublicationNadwaga i otyłość stanowią poważny problem zdrowotny na całym świecie. Są czynnikiem ryzyka wielu chorób przewlekłych, zwłaszcza chorób sercowo-naczyniowych, metabolicznych, a także niektórych nowotworów. Praca ma na celu ocenę rozpowszechnienia nadwagi i otyłości w populacji wiejskiej.